Routes Europe Opens Amidst Global Open Skies Debate

Go back to Routes Europe Opens Amidst Global Open Skies Debate

Shire's (SHPG) Phase 2 IMAGO Missed Primary, Secondary Endpoints

April 9, 2015 6:09 AM EDT

Shire plc (NASDAQ: SHPG) announced that the 13-week Phase 2 IMAGO trial of its investigational compound SHP625 (LUM001) did not meet the primary or secondary endpoints in the study of 20 pediatric patients with Alagille syndrome (ALGS), a rare, life-threatening genetic disorder that presents with chronic cholestasis (accumulation of bile acids in the liver) and severe pruritus (itching). The primary endpoint was the... More