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Form 3 Freenome, Inc. For: Jul 20 Filed by: EDELMAN JOSEPH

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July 22, 2026 8:51 PM EDT
FORM 3 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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OMB Number: 3235-0104
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hours per response: 0.5
1. Name and Address of Reporting Person *
PERCEPTIVE ADVISORS LLC
(Last) (First) (Middle)
51 ASTOR PLACE, 10TH FLOOR
(Street)
NEW YORK NY 10003
(City) (State) (Zip)
2. Date of Event Requiring Statement (Month/Day/Year)
07/20/2026 		3. Issuer Name and Ticker or Trading Symbol
Freenome, Inc. [ FRNM ]
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director X 10% Owner
Officer (give title below) Other (specify below)
5. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
X Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock 1,241,563 (1)
D (2)
 
Common Stock 1,711,065 (3)
D (2)
 
Common Stock 1,654,500 (4)
D (2)
 
Common Stock 764,719 (5)
D (2)
 
Table II - Derivative Securities Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4) 2. Date Exercisable and Expiration Date (Month/Day/Year) 3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 6. Nature of Indirect Beneficial Ownership (Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Explanation of Responses:
1. Represents shares of common stock of the Issuer corresponding to shares of Series B Preferred Stock of Freenome Holdings, Inc. held by the Reporting Persons, on an as-converted basis, in connection with the business combination between Freenome Holdings, Inc. and Perceptive Capital Solutions Corp. pursuant to the Business Combination Agreement, dated as of December 5, 2025 (the "Business Combination").
2. The securities are directly held by Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of the Master Fund. Joseph Edelman ("Mr. Edelman") serves as the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of their indirect pecuniary interest therein, and this report shall not be deemed an admission that the Advisor or Mr. Edelman is a beneficial owner of such securities for purposes of Section 16 or for any other purpose.
3. Represents shares of common stock of the Issuer corresponding to shares of Legacy Freenome Series C Preferred Stock held by the Reporting Persons, on an as-converted basis, in connection with the Business Combination.
4. Represents shares of common stock of the Issuer corresponding to shares of Legacy Freenome Series D Preferred Stock held by the Reporting Persons, on an as-converted basis, in connection with the Business Combination.
5. Represents shares of common stock of the Issuer corresponding to shares of Legacy Freenome Series F Preferred Stock held by the Reporting Persons, on an as-converted basis, in connection with the Business Combination.
/s/ Joseph Edelman - for Perceptive Advisors LLC, By: Joseph Edelman, its managing member 07/22/2026
** Signature of Reporting Person Date
/s/ Joseph Edelman - for Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager, By: Joseph Edelman, its managing member 07/22/2026
** Signature of Reporting Person Date
/s/ Joseph Edelman 07/22/2026
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

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