Form NSAR-B VANGUARD QUANTITATIVE For: Sep 30

      PAGE  1
000 B000000 09/30/2017
000 C000000 0000799127
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 VANGUARD QUANTITATIVE FUNDS
001 B000000 811-4526
001 C000000 6106691000
002 A000000 100 VANGUARD BOULEVARD
002 B000000 MALVERN
002 C000000 PA
002 D010000 19355
003  000000 N
004  000000 N
005  000000 N
006  000000 N
007 A000000 N
007 B000000  0
007 C010100  1
008 A000001 DELETE
008 A000002 THE VANGUARD GROUP, INC.
008 B000002 A
008 C000002 801-11953
008 D010002 MALVERN
008 D020002 PA
008 D030002 19355
008 A000003 D. E. SHAW INVESTMENT MANAGEMENT, L.L.C
008 B000003 A
008 C000003 801-64222
008 D010003 New York
008 D020003 NY
008 D030003 10036
008 A000004 L.A. CAPITAL MANAGEMENT&EQUITY RESEARCH, INC.
008 B000004 A
008 C000004 801-60934
008 D010004 LOS ANGELES
008 D020004 CA
008 D030004 90025
010 A000001 THE VANGUARD GROUP, INC.
010 B000001 801-11953
010 C010001 MALVERN
010 C020001 PA
010 C030001 19355
011 A000001 VANGUARD MARKETING CORP.
011 B000001 8-21570
011 C010001 MALVERN
011 C020001 PA
      PAGE  2
011 C030001 19355
012 A000001 THE VANGUARD GROUP, INC.
012 B000001 84-772
012 C010001 MALVERN
012 C020001 PA
012 C030001 19355
013 A000001 PRICEWATERHOUSECOOPERS LLP
013 B010001 PHILADELPHIA
013 B020001 PA
013 B030001 19103
014 A000001 VANGUARD MARKETING CORP.
014 B000001 8-21570
015 A000001 State Street Bank and Trust Company
015 B000001 C
015 C010001 Boston
015 C020001 MA
015 C030001 02111
015 E010001 X
018  000000 Y
019 A000000 Y
019 B000000  198
019 C000000 VANGUARDGR
020 A000001 JEFFERIES & COMPANY, INC.
020 B000001 95-2622900
020 C000001    108
020 A000002 PERSHING LLC
020 B000002 13-2741729
020 C000002     94
020 A000003 Bernstein (Sanford C.) & Co., Inc.
020 B000003 13-2625874
020 C000003     82
020 A000004 CREDIT SUISSE SECURITIES (USA) LLC
020 B000004 13-5659485
020 C000004     76
020 A000005 ITG, INC.
020 B000005 95-4339369
020 C000005     69
020 A000006 LIQUIDNET, INC.
020 B000006 13-4095933
020 C000006     64
020 A000007 J.P. MORGAN SECURITIES INC.
020 B000007 13-3224016
020 C000007     51
020 A000008 MERRILL LYNCH, PIERCE, FENNER & SMITH INC.
020 B000008 13-5674085
020 C000008     49
020 A000009 CITATION
020 C000009     44
020 A000010 MORGAN STANLEY
020 B000010 13-2655998
020 C000010     36
      PAGE  3
021  000000      778
022 A000001 VANGUARD MARKET LIQUIDITY FUND
022 B000001 20-0961056
022 C000001   1292101
022 D000001   1210824
022 A000002 DEUTSCHE BANK SECURITIES INC.
022 B000002 13-2730828
022 C000002    185019
022 D000002    184555
022 A000003 FMC Technologies
022 C000003         0
022 D000003     18254
022 A000004 TECHNIPFMC PLC
022 C000004     18254
022 D000004         0
022 A000005 Normura Securities
022 C000005      9859
022 D000005       200
022 A000006 GOLDMAN, SACHS & CO.
022 B000006 13-5108880
022 C000006      4995
022 D000006         0
022 A000007 CITIGROUP GLOBAL MARKETS, INC.
022 B000007 13-2919773
022 C000007      3990
022 D000007         0
022 A000008 MORGAN STANLEY
022 B000008 13-2655998
022 C000008      3987
022 D000008         0
022 A000009 VANGUARD MARKETING CORP.
022 C000009      2241
022 D000009      1420
022 A000010 BARCLAYS CAPITAL INC.
022 B000010 13-3410233
022 C000010      2345
022 D000010        30
023 C000000    1526642
023 D000000    1417925
024  000000 Y
025 A000001 J.P. MORGAN SECURITIES INC.
025 B000001 13-3224016
025 C000001 E
025 D000001  152588
025 A000002 CITIGROUP GLOBAL MARKETS, INC.
025 B000002 13-2919773
025 C000002 E
025 D000002   97343
025 A000003 MORGAN STANLEY
025 B000003 13-2655998
025 C000003 E
      PAGE  4
025 D000003   35186
025 A000004 FMC Technologies
025 C000004 E
025 D000004   12329
025 A000005 TECHNIPFMC PLC
025 C000005 E
025 D000005      34
025 A000006 GOLDMAN, SACHS & CO.
025 B000006 13-5108880
025 C000006 E
025 D000006   54225
025 A000007 Bank of America
025 B000007 56-2058405
025 C000007 E
025 D000007  121625
026 A000000 N
026 B000000 Y
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 Y
026 H000000 N
027  000000 Y
028 A010000     63090
028 A020000         0
028 A030000         0
028 A040000     68103
028 B010000     70787
028 B020000         0
028 B030000         0
028 B040000    119335
028 C010000     68129
028 C020000     56575
028 C030000         0
028 C040000     72197
028 D010000     57251
028 D020000         0
028 D030000         0
028 D040000     67750
028 E010000    204721
028 E020000         0
028 E030000         0
028 E040000    232254
028 F010000   2232121
028 F020000         0
028 F030000         0
028 F040000     79909
028 G010000   2696099
028 G020000     56575
      PAGE  5
028 G030000         0
028 G040000    639548
028 H000000         0
029  000000 N
030 A000000      0
030 B000000  0.00
030 C000000  0.00
031 A000000      0
031 B000000      0
032  000000      0
033  000000      0
034  000000 N
035  000000      0
036 B000000      0
037  000000 N
038  000000      0
039  000000 Y
040  000000 N
042 A000000   0
042 B000000   0
042 C000000   0
042 D000000   0
042 E000000   0
042 F000000   0
042 G000000   0
042 H000000   0
043  000000      0
044  000000      0
045  000000 Y
046  000000 Y
047  000000 N
048  000000  0.000
048 A010000        0
048 A020000 0.000
048 B010000        0
048 B020000 0.000
048 C010000        0
048 C020000 0.000
048 D010000        0
048 D020000 0.000
048 E010000        0
048 E020000 0.000
048 F010000        0
048 F020000 0.000
048 G010000        0
048 G020000 0.000
048 H010000        0
048 H020000 0.000
048 I010000        0
048 I020000 0.000
048 J010000        0
      PAGE  6
048 J020000 0.000
048 K010000        0
048 K020000 0.000
049  000000 N
050  000000 N
051  000000 Y
052  000000 N
053 A000000 N
054 A000000 N
054 B000000 N
054 C000000 N
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 N
054 H000000 N
054 I000000 N
054 J000000 N
054 K000000 N
054 L000000 N
054 M000000 N
054 N000000 N
054 O000000 N
055 A000000 N
055 B000000 N
056  000000 Y
057  000000 N
058 A000000 N
059  000000 Y
060 A000000 Y
060 B000000 Y
061  000000        0
062 A000000 N
062 B000000   0.0
062 C000000   0.0
062 D000000   0.0
062 E000000   0.0
062 F000000   0.0
062 G000000   0.0
062 H000000   0.0
062 I000000   0.0
062 J000000   0.0
062 K000000   0.0
062 L000000   0.0
062 M000000   0.0
062 N000000   0.0
062 O000000   0.0
062 P000000   0.0
062 Q000000   0.0
062 R000000   0.0
063 A000000   0
      PAGE  7
063 B000000  0.0
066 A000000 Y
066 B000000 N
066 C000000 N
066 D000000 N
066 E000000 Y
066 F000000 N
066 G000000 N
067  000000 N
068 A000000 N
068 B000000 N
069  000000 N
070 A010000 Y
070 A020000 N
070 B010000 Y
070 B020000 N
070 C010000 Y
070 C020000 N
070 D010000 Y
070 D020000 N
070 E010000 Y
070 E020000 N
070 F010000 Y
070 F020000 Y
070 G010000 Y
070 G020000 N
070 H010000 Y
070 H020000 N
070 I010000 Y
070 I020000 N
070 J010000 Y
070 J020000 N
070 K010000 Y
070 K020000 Y
070 L010000 Y
070 L020000 Y
070 M010000 Y
070 M020000 N
070 N010000 Y
070 N020000 Y
070 O010000 Y
070 O020000 N
070 P010000 Y
070 P020000 N
070 Q010000 Y
070 Q020000 N
070 R010000 Y
070 R020000 N
071 A000000   9133674
071 B000000   6883749
071 C000000   7196369
      PAGE  8
071 D000000   96
072 A000000 12
072 B000000     2266
072 C000000   154513
072 D000000        0
072 E000000      148
072 F000000     7652
072 G000000     6905
072 H000000        0
072 I000000     4137
072 J000000      227
072 K000000        0
072 L000000      347
072 M000000       17
072 N000000        0
072 O000000        0
072 P000000        0
072 Q000000        0
072 R000000       27
072 S000000        0
072 T000000      695
072 U000000        0
072 V000000        0
072 W000000        0
072 X000000    20007
072 Y000000        0
072 Z000000   136920
072AA000000   659043
072BB000000   210208
072CC010000   616233
072CC020000        0
072DD010000    53480
072DD020000    81075
072EE000000   316500
073 A010000   0.7990
073 A020000   1.3840
073 B000000   0.0000
073 C000000   0.0000
074 A000000       69
074 B000000        0
074 C000000    11284
074 D000000        0
074 E000000        0
074 F000000  9766349
074 G000000        0
074 H000000        0
074 I000000   234749
074 J000000    25962
074 K000000        0
074 L000000    11405
074 M000000        0
      PAGE  9
074 N000000 10049818
074 O000000    30638
074 P000000    13299
074 Q000000        0
074 R010000        0
074 R020000        0
074 R030000        0
074 R040000     9027
074 S000000        0
074 T000000  9996854
074 U010000    64123
074 U020000    92387
074 V010000    46.50
074 V020000    75.93
074 W000000   0.0000
074 X000000   154216
074 Y000000     8489
075 A000000        0
075 B000000  7419260
076  000000     0.00
077 A000000 Y
077 B000000 Y
077 C000000 N
077 D000000 N
077 E000000 N
077 F000000 N
077 G000000 N
077 H000000 N
077 I000000 N
077 J000000 N
077 K000000 N
077 L000000 N
077 M000000 N
077 N000000 N
077 O000000 N
077 P000000 N
077 Q010000 N
077 Q020000 N
077 Q030000 Y
078  000000 N
080 A000000 ICI Mutual Insurance Company
080 B000000 N/A
080 C000000   400000
081 A000000 Y
081 B000000 211
082 A000000 N
082 B000000        0
083 A000000 N
083 B000000        0
084 A000000 N
084 B000000        0
      PAGE  10
085 A000000 Y
085 B000000 N
086 A010000      0
086 A020000      0
086 B010000      0
086 B020000      0
086 C010000      0
086 C020000      0
086 D010000      0
086 D020000      0
086 E010000      0
086 E020000      0
086 F010000      0
086 F020000      0
SIGNATURE   RYAN GRAY
TITLE       MANAGER
 

Report of Independent Registered Public Accounting 
Firm

To the Board of Trustees of Vanguard Quantitative Funds and the 
Shareholders of
Vanguard Growth and Income Fund

In planning and performing our audits of the financial 
statements of Vanguard Growth and Income Fund (hereafter 
referred to as the ?Trust?) as of and for the year ended September 
30, 2017, in accordance with the standards of the Public 
Company Accounting Oversight Board (United States), we 
considered the Trust's internal control over financial reporting, 
including controls over safeguarding securities, as a basis for 
designing our auditing procedures for the purpose of expressing 
our opinion on the financial statements and to comply with the 
requirements of Form N-SAR, but not for the purpose of 
expressing an opinion on the effectiveness of the Trust's internal 
control over financial reporting.  Accordingly, we do not express 
an opinion on the effectiveness of the Trust's internal control 
over financial reporting.

The management of the Trust is responsible for establishing and 
maintaining effective internal control over financial reporting.  In 
fulfilling this responsibility, estimates and judgments by 
management are required to assess the expected benefits and 
related costs of controls.  A company?s internal control over 
financial reporting is a process designed to provide reasonable 
assurance regarding the reliability of financial reporting and the 
preparation of financial statements for external purposes in 
accordance with generally accepted accounting principles.  A 
company's internal control over financial reporting includes 
those policies and procedures that (1) pertain to the maintenance 
of records that, in reasonable detail, accurately and fairly reflect 
the transactions and dispositions of the assets of the company; 
(2) provide reasonable assurance that transactions are recorded 
as necessary to permit preparation of financial statements in 
accordance with generally accepted accounting principles, and 
that receipts and expenditures of the company are being made 
only in accordance with authorizations of management and 
trustees of the company; and (3) provide reasonable assurance 
regarding prevention or timely detection of unauthorized 
acquisition, use or disposition of a company?s assets that could 
have a material effect on the financial statements.

Because of its inherent limitations, internal control over financial 
reporting may not prevent or detect misstatements.  Also, 
projections of any evaluation of effectiveness to future periods 
are subject to the risk that controls may become inadequate 
because of changes in conditions, or that the degree of 
compliance with the policies or procedures may deteriorate.

A deficiency in internal control over financial reporting exists 
when the design or operation of a control does not allow 
management or employees, in the normal course of performing 
their assigned functions, to prevent or detect misstatements on a 
timely basis.  A material weakness is a deficiency, or a 
combination of deficiencies, in internal control over financial 
reporting, such that there is a reasonable possibility that a 
material misstatement of the Trust's annual or interim financial 
statements will not be prevented or detected on a timely basis.  

Our consideration of the Trust's internal control over financial 
reporting was for the limited purpose described in the first 
paragraph and would not necessarily disclose all deficiencies in 
internal control over financial reporting that might be material 
weaknesses under standards established by the Public Company 
Accounting Oversight Board (United States).  However, we noted 
no deficiencies in the Trust's internal control over financial 
reporting and its operation, including controls over safeguarding 
securities, that we consider to be material weaknesses as defined 
above as of September 30, 2017.

This report is intended solely for the information and use of 
management and the Board of Trustees of Vanguard Quantitative 
Funds and the Securities and Exchange Commission and is not 
intended to be and should not be used by anyone other than 
these specified parties.

/s/PricewaterhouseCoopers LLP
Philadelphia, Pennsylvania 
November 13, 2017

2

EXHIBIT 77Q3 TO FORM N-SAR

Registrant Name: Vanguard Quantitative Funds
File Number: 811-04526
Registrant CIK Number: 0000799127


Items 72, 73 and 74

     Because  the  electronic  format  for filing  Form  N-SAR does not  provide
adequate space for responding to Items 72 through 74 completely,  the Registrant
has set forth in their entirety the complete responses to the indicated Items or
Sub-Items  below,  in  accordance  with  verbal  instructions  provided  to  the
Registrant by the staff of the  Commission on September 20, 2002,  and September
23, 2002.

                                





Series 1 Identifier S000002913
Class 1 SEC Identifier C000007979
Class 2 SEC Identifier C000007980



Item 73

Distributions per share for which record date passed during the period:


B)      1. Distributions of capital gains 						  $1.999
								                                                                          
        2. Distributions of capital gains from a second class of open-end 
company shares  						                          $3.262

You May Also Be Interested In

• Adagene doses first patient in combo trial for colorectal cancer
• Palantir names Aplos Data to top tier of its partner network
• Workhorse signs first Canadian dealer deal with Tristan Fleet