Form 10-Q REXAHN PHARMACEUTICALS, For: Mar 31

May 6, 2016 4:31 PM EDT

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-Q
   
   (Mark One)  
 
QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
 
 
For the quarterly period ended March 31, 2016

OR

TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from             to            

Commission File No.:001-34079
Rexahn Pharmaceuticals, Inc.
(Exact name of registrant as specified in its charter)

Delaware
 
11-3516358
(State or Other Jurisdiction of Incorporation or Organization)
 
(I.R.S. Employer Identification No.)

15245 Shady Grove Road, Suite 455
Rockville, MD 20850
(Address of Principal Executive Offices, Including Zip Code)

Telephone: (240) 268-5300
(Registrant’s Telephone Number, Including Area Code)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes   No

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes No

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or a smaller reporting company. See definition of “accelerated filer,” “large accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

Large Accelerated Filer
Accelerated Filer
Non-Accelerated Filer
Smaller reporting company
(Do not check if a smaller reporting company)

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act) Yes   No

Indicate the number of shares outstanding of each of the issuer’s classes of common stock, as of the latest practicable date: 213,173,785 shares as of May 6, 2016
 


REXAHN PHARMACEUTICALS, INC.
TABLE OF CONTENTS
 
 
Page
 
 
PART I
FINANCIAL INFORMATION
1
Item 1
1
 
1
 
2
 
3
 
4
 
5
Item 2
25
Item 3
33
Item 4
33
     
PART II
OTHER INFORMATION
34
Item 1A
34
Item 2
34
Item 6
34
 
 
35
 
PART I. Financial Information
Item 1.
Financial Statements

REXAHN PHARMACEUTICALS, INC.
Condensed Balance Sheet
(Unaudited)
 
   
March 31, 2016
   
December 31, 2015
 
ASSETS
 
Current Assets:
           
Cash and cash equivalents
 
$
10,463,654
   
$
10,199,440
 
Marketable securities
   
14,005,173
     
13,240,086
 
Prepaid expenses and other current assets
   
946,061
     
1,221,818
 
Total Current Assets
   
25,414,888
     
24,661,344
 
Security Deposits
   
30,785
     
30,785
 
Equipment, Net
   
111,335
     
112,900
 
Total Assets
 
$
25,557,008
   
$
24,805,029
 
LIABILITIES AND STOCKHOLDERS’ EQUITY
 
Current Liabilities:
               
Accounts payable and accrued expenses
 
$
3,284,267
   
$
2,661,298
 
                 
Deferred Research and Development Arrangement
   
506,250
     
525,000
 
                 
Other Liabilities
   
98,308
     
104,020
 
                 
Warrant Liabilities
   
4,459,068
     
2,739,163
 
                 
Total Liabilities
   
8,347,893
     
6,029,481
 
Commitments and Contingencies (note 14)
               
Stockholders’ Equity:
               
Preferred stock, par value $0.0001, 100,000,000 authorized shares, none issued and outstanding
   
-
     
-
 
Common stock, par value $0.0001, 500,000,000 authorized shares, 213,173,785 and 197,413,785 issued and outstanding
   
21,317
     
19,741
 
Additional paid-in capital
   
127,055,110
     
124,490,712
 
Accumulated other comprehensive loss
   
(1,406
)
   
(18,041
)
Accumulated deficit
   
(109,865,906
)
   
(105,716,864
)
                 
Total Stockholders’ Equity
   
17,209,115
     
18,775,548
 
                 
Total Liabilities and Stockholders’ Equity
 
$
25,557,008
   
$
24,805,029
 
 
(See accompanying notes to the condensed financial statements)
 
REXAHN PHARMACEUTICALS, INC.
Condensed Statement of Operations
(Unaudited)

   
For the Three Months Ended March 31,
 
   
2016
   
2015
 
Revenues:
 
$
-
   
$
-
 
                 
Expenses:
               
General and administrative
   
1,395,406
     
1,524,700
 
Research and development
   
3,468,575
     
2,893,008
 
                 
Total Expenses
   
4,863,981
     
4,417,708
 
                 
Loss from Operations
   
(4,863,981
)
   
(4,417,708
)
                 
Other Income (Expense)
               
Interest income
   
28,871
     
30,582
 
Unrealized gain on fair value of warrants
   
855,955
     
115,415
 
Financing expense
   
(169,887
)
   
-
 
Total Other Income (Expense)
   
714,939
     
145,997
 
                 
Net Loss Before Provision for Income Taxes
   
(4,149,042
)
   
(4,271,711
)
Provision for income taxes
   
-
     
-
 
Net Loss
 
$
(4,149,042
)
 
$
(4,271,711
)
                 
Net loss per share, basic and diluted
 
$
(0.02
)
 
$
(0.02
)
                 
Weighted average number of shares outstanding, basic and diluted
   
202,586,807
     
179,097,897
 
 
(See accompanying notes to the condensed financial statements)
 
REXAHN PHARMACEUTICALS, INC.
Condensed Statement of Comprehensive Loss
(Unaudited)

   
For the Three Months Ended March 31,
 
   
2016
   
2015
 
             
Net Loss
 
$
(4,149,042
)
 
$
(4,271,711
)
                 
Unrealized gain on available-for-sale securities
   
16,635
     
34,723
 
                 
Comprehensive Loss
 
$
(4,132,407
)
 
$
(4,236,988
)
 
(See accompanying notes to the condensed financial statements)
 
REXAHN PHARMACEUTICALS, INC.
Condensed Statement of Cash Flows
(Unaudited)

   
For the Three Months Ended March 31,
 
   
2016
   
2015
 
Cash Flows from Operating Activities:
           
Net loss
 
$
(4,149,042
)
 
$
(4,271,711
)
Adjustments to reconcile net loss to net cash used in operating activities:
               
Compensatory stock
   
48,749
     
56,250
 
Depreciation and amortization
   
6,161
     
6,165
 
Amortization of premiums and discounts on marketable securities, net
   
13,308
     
6,778
 
Stock-based compensation
   
343,011
     
272,386
 
Amortization of deferred research and development arrangements
   
(18,750
)
   
(18,750
)
Unrealized gain on fair value of warrants
   
(855,955
)
   
(115,415
)
Financing expense
   
169,887
     
-
 
Amortization of deferred lease incentive
   
(3,111
)
   
(3,111
)
Deferred lease expenses
   
(2,601
)
   
(1,645
)
Changes in assets and liabilities:
               
Prepaid expenses and other assets
   
275,757
     
(260,040
)
Accounts payable and accrued expenses
   
622,969
     
290,276
 
Net Cash Used in Operating Activities
   
(3,549,617
)
   
(4,038,817
)
Cash Flows from Investing Activities:
               
Purchase of equipment
   
(4,596
)
   
(7,935
)
Purchase of marketable securities
   
(1,721,760
)
   
(740,825
)
Redemption of marketable securities
   
960,000
     
4,985,000
 
Net Cash (Used In) Provided by Investing Activities
   
(766,356
)
   
4,236,240
 
Cash Flows from Financing Activities:
               
Issuance of common stock and units, net of issuance costs
   
4,580,187
     
-
 
Proceeds from exercise of stock options
   
-
     
705,542
 
Net Cash Provided by Financing Activities
   
4,580,187
     
705,542
 
Net Increase in Cash and Cash Equivalents
   
264,214
     
902,965
 
Cash and Cash Equivalents – beginning of period
   
10,199,440
     
9,826,245
 
Cash and Cash Equivalents - end of period
 
$
10,463,654
   
$
10,729,210
 
Supplemental Cash Flow Information
               
Non-cash financing and investing activities:
               
Warrants issued
 
$
2,575,860
   
$
-
 
 
(See accompanying notes to the condensed financial statements)
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)
 
1.
Operations and Organization

Operations
Rexahn Pharmaceuticals, Inc. (the “Company,”), a Delaware corporation, is a biopharmaceutical company whose principal operations are the discovery, development and commercialization of innovative treatments for cancer.  The Company had an accumulated deficit of $109,865,906 at March 31, 2016 and anticipates incurring losses through fiscal year 2016 and beyond.  The Company has not yet generated commercial revenues and has funded its operating losses to date through the sale of shares of its common stock and warrants to purchase shares of its common stock, convertible debt, financings, interest income from cash, cash equivalents and marketable securities, and proceeds from reimbursed research and development costs.  The Company believes that its cash, cash equivalents, and marketable securities, will be sufficient to cover its cash flow requirements for its current activities for at least the next 12 months.  Management believes it has the capability of managing the Company’s operations within existing cash available by focusing on select research and development activities, selecting projects in conjunction with potential financings and milestones, and efficiently managing its general and administrative affairs.

Basis of Presentation
The accompanying unaudited condensed financial statements of the Company have been prepared pursuant to the rules and regulations of the U.S. Securities and Exchange Commission for interim financial information.  Accordingly, they do not include all of the information and footnotes required by accounting principles generally accepted in the United States (“U.S. GAAP”) for complete financial statements.  In the opinion of the Company’s management, all adjustments (consisting of only normal recurring accruals) considered necessary for a fair presentation of the Company’s financial position as of March 31, 2016 and December 31, 2015 and of the results of operations, comprehensive loss and cash flows for the three months ended March 31, 2016 and 2015 have been included.  Operating results for the three months ended March 31, 2016 are not necessarily indicative of results that may be expected for any other interim period or the full fiscal year ending December 31, 2016. The accompanying unaudited condensed financial statements should be read in conjunction with the audited financial statements and notes thereto included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2015 (the “2015 Form 10-K”).  Information included in the condensed balance sheet as of December 31, 2015 has been derived from the Company’s audited financial statements for the year ended December 31, 2015 included in the 2015 Form 10-K.

Use of Estimates
The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period.  These estimates are based on management’s best knowledge of current events and actions the Company may undertake in the future.  Actual results may ultimately differ from these estimates.  These estimates are reviewed periodically, and as adjustments become necessary, they are reported in earnings in the period in which they become available.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

2. Recent Accounting Pronouncements Affecting the Company

Revenue from Contracts with Customers

In May 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) 2014-09, “Revenue from Contracts with Customers,” a comprehensive new revenue recognition standard that will supersede nearly all existing revenue recognition guidance under U.S. GAAP. The standard’s core principle is that a company should recognize revenue when it transfers goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for those goods and services, and provides a revenue recognition framework in accordance with this principle.  On August 12, 2015, the FASB issued ASU 2015-14, which defers the effective date of ASU 2014-09 by one year to December 15, 2017 for annual reporting periods beginning after that date and interim periods therein.  Early adoption of the standard is permitted, but not before the original effective date of December 15, 2016.  The Company is currently evaluating the impact that the adoption of this guidance will have on its financial statements and future operating results.

Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern

In August 2014, the FASB issued ASU 2014-15, “Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern,” which requires management to perform interim and annual assessments as to the entity’s ability to continue as a going concern and provides related disclosure guidance.  ASU 2014-15 will be effective for reporting periods beginning after December 15, 2016, with early adoption permitted. The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.

Leases

In February 2016, the FASB issued ASU 2016-02, “Leases,” which requires an entity to recognize assets and liabilities arising from leases on the balance sheet and to provide additional disclosures about leasing arrangements.  ASU 2016-02 will be effective for reporting periods beginning after December 15, 2018, with early adoption permitted. The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.

Compensation-Stock Compensation

In March 2016, the FASB issued ASU 2016-09, “Compensation-Stock Compensation: Improvements to Employee Share Based Payment Accounting,” which includes multiple provisions intended to simplify various aspects of accounting for share-based payments.  The guidance is effective for reporting periods beginning after December 15, 2016, with early adoption permitted.  The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

3. Marketable Securities

Marketable securities are considered “available-for-sale” in accordance with FASB Accounting Standard Codification (“ASC”) 320, “Debt and Equity Securities,” and thus are reported at fair value in the Company’s accompanying balance sheet, with unrealized gains and losses excluded from earnings and reported as a separate component of stockholders’ equity.  Amounts reclassified out of accumulated other comprehensive income (loss) into realized gains and losses are accounted for on the basis of specific identification and are included in other income or expense in the statement of operations.  The Company classifies such investments as current on the balance sheet as the investments are readily marketable and available for use in current operations.

The following table shows the Company’s marketable securities’ adjusted cost, gross unrealized gains and losses, and fair value by significant investment category as of March 31, 2016 and December 31, 2015:
 
   
March 31, 2016
 
   
Cost
Basis
   
Gross
Unrealized
Gains
   
Gross
Unrealized
Losses
   
Fair
Value
 
Certificates of Deposit
 
$
6,000,000
   
$
2,227
   
$
(804
)
 
$
6,001,423
 
Commercial Paper
   
2,986,944
     
-
     
(2,124
)
   
2,984,820
 
Corporate Bonds
   
5,019,635
     
138
     
(843
)
   
5,018,930
 
Total Marketable Securities
 
$
14,006,579
   
$
2,365
   
$
(3,771
)
 
$
14,005,173
 

   
December 31, 2015
 
   
Cost
Basis
   
Gross
Unrealized
Gains
   
Gross
Unrealized
Losses
   
Fair
Value
 
Certificates of Deposit
 
$
6,240,000
   
$
571
   
$
(5,575
)
 
$
6,234,996
 
Commercial Paper
   
2,981,307
     
-
     
(3,737
)
   
2,977,570
 
Corporate Bonds
   
4,036,820
     
-
     
(9,300
)
   
4,027,520
 
Total Marketable Securities
 
$
13,258,127
   
$
571
   
$
(18,612
)
 
$
13,240,086
 

The Company typically invests in highly-rated securities, with the primary objective of minimizing the potential risk of principal loss.  As of March 31, 2016, the Company had 11 certificates of deposit with a fair value of $2,639,196 and unrealized losses of $804, three commercial papers with an aggregate fair value of $2,984,820 and unrealized losses of $2,124, and three corporate bonds with an aggregate fair value of $3,014,440 and unrealized losses of $656, all of which have been unrealized losses for less than 12 months.  The Company has one corporate bond with a fair value of $1,001,890 and unrealized losses of $187 which has been an unrealized loss for greater than 12 months.  The Company does not intend to sell its marketable securities in an unrealized loss position.  Based upon these securities’ fair value relative to the cost, high ratings, and volatility of fair value, the Company considers the declines in market value of its marketable securities to be temporary in nature and does not consider any of its investments other-than-temporarily impaired, and anticipates that it will recover the entire amortized cost basis.

As of March 31 2016, all of the Company’s marketable securities are expected to mature in less than one year.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

4. Prepaid Expenses and Other Current Assets

    
March 31,
2016
   
December 31,
2015
 
             
Deposits on contracts
 
$
316,743
   
$
501,170
 
Prepaid expenses and other current assets
   
629,318
     
720,648
 
                 
   
$
946,061
   
$
1,221,818
 

Deposits on contracts consist of deposits on research and development contracts for services that had not been incurred as of the balance sheet date.  Prepaid expenses and other assets include prepaid general and administrative expenses, such as insurance, rent, investor relations fees and compensatory stock issued for services not yet incurred as of the balance sheet date.

5.
Equipment, Net

   
March 31,
2016
   
December 31,
2015
 
             
Furniture and fixtures
 
$
78,794
   
$
78,794
 
Office and computer equipment
   
109,862
     
105,266
 
Lab equipment
   
431,650
     
431,650
 
Leasehold improvements
   
133,762
     
133,762
 
                 
Total equipment
   
754,068
     
749,472
 
Less: Accumulated depreciation and amortization
   
(642,733
)
   
(636,572
)
                 
Net carrying amount
 
$
111,335
   
$
112,900
 

6.
Accounts Payable and Accrued Expenses

   
March 31,
2016
   
December 31,
2015
 
             
Trade payables
 
$
1,132,858
   
$
774,543
 
Accrued expenses
   
125,725
     
92,752
 
Accrued research and development contract costs
   
1,884,445
     
1,515,151
 
Payroll liabilities
   
141,239
     
278,852
 
                 
   
$
3,284,267
   
$
2,661,298
 
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

7.
Deferred Research and Development Arrangements

Rexgene Biotech Co., Ltd.
 
In 2003, the Company entered into a collaborative research agreement with Rexgene Biotech Co., Ltd. (“Rexgene”), a shareholder.  Rexgene is engaged in the development of pharmaceutical products in Asia and has agreed to assist the Company with the research, development and clinical trials necessary for registration of the Company’s drug candidate Archexin in Asia.  This agreement provides Rexgene with exclusive rights to license, sublicense, make, have made, use, sell and import Archexin in Asia.  In accordance with the agreement, Rexgene paid the Company a one-time fee of $1,500,000 in 2003.  The agreement terminates at the later of 20 years or the term of the patent.  The amortization reduces research and development expenses for the periods presented.

The Company is using 20 years as its basis for recognition and accordingly research and development expenses were reduced by $18,750 for the three months ended March 31, 2016 and 2015.  The remaining $506,250 and $525,000 to be amortized at March 31, 2016 and December 31, 2015, respectively, is reflected as a deferred research and development arrangement on the balance sheet.  The payment from Rexgene is being used in the cooperative funding of the costs of development of Archexin. Royalties of 3% of net sales of licensed products will become payable by Rexgene to the Company on a quarterly basis once commercial sales of Archexin begin in Asia.  The product is still under development and commercial sales in Asia are not expected to begin until at least 2017.  Under the terms of the agreement, Rexgene does not receive royalties on the Company’s net sales outside of Asia.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

8. Other Liabilities

Deferred Lease Incentive

In accordance with the Company’s office lease agreement, as amended and further discussed in Note 14, the Company has been granted leasehold improvement allowances from the lessor to be used for the construction cost of improvements to the leased property, which included architectural and engineering fees, government agency plan check, permit and other fees, sales and use taxes, testing and inspection costs and telephone and data cabling and wiring in the premises.  The Company accounted for the benefit of the leasehold improvement allowance as a reduction of rental expense over the term of the office lease.
 
The following table sets forth the cumulative deferred lease incentive:

   
March 31,
2016
   
December 31,
2015
 
             
Deferred lease incentive
 
$
154,660
   
$
154,660
 
Less accumulated amortization
   
(114,219
)
   
(111,108
)
                 
Balance
 
$
40,441
   
$
43,552
 

Deferred Office Lease Expense

The lease agreement, as amended, provided for an initial annual base rent with annual increases over the lease term.  The Company recognizes rental expense on a straight-line basis over the term of the lease, which resulted in a deferred rent liability of $57,867 and $60,468 as of March 31, 2016 and December 31, 2015, respectively.

9.
Net Loss per Common Share

Basic loss per common share is computed by dividing net loss by the weighted average number of shares of common stock outstanding for the period.  Diluted loss per common share is computed by dividing net loss by the weighted average number of shares of common stock outstanding, plus the number of common share equivalents that would be dilutive.  As of March 31, 2016 and December 31, 2015, there were stock options and warrants to acquire, in the aggregate, 54,919,976 and 39,082,886 shares of the Company’s common stock, respectively, that are potentially dilutive. However, diluted loss per share for all periods presented is the same as basic loss per share because the inclusion of common share equivalents would be anti-dilutive.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)
 
10.
Common Stock

The following transactions occurred since December 31, 2015:

Public Offering

On March 2, 2016 the Company closed on a registered direct public offering to issue and sell 15,625,000 shares of common stock and warrants to purchase up to 11,718,750 shares of common stock.  The common stock and warrants were sold in units, consisting of common stock and a warrant to purchase 0.75 shares of common stock, at a price of $0.32 per unit, and the warrants have an exercise price of $0.42 per share.  The total gross proceeds of the offering were $5,000,000.  The warrants issued are exercisable beginning six months after the closing date until the five-year anniversary of the initial exercise date and were recorded as liabilities at fair value.

A summary of the allocation of the proceeds of the offering is shown below:

Gross Proceeds:
 
$
5,000,000
 
         
Allocated to warrant liabilities:
   
2,419,922
 
Allocated to common stock and additional paid-in capital
   
2,580,078
 
         
Total allocated gross proceeds:
 
$
5,000,000
 

The closing costs of $575,751 included 781,250 warrants valued at $155,938 and $419,813 for placement agent and other fees.  Based upon the estimated fair value of the stock and warrants in the units, the Company allocated $169,887 to financing expense and $405,864 as stock issuance costs.

Compensatory Shares
 
During the three months ended March 31, 2016, the Company issued 135,000 shares to vendors in exchange for investor relations services.  The aggregate market value of the stock issued was $48,749.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

11.
Stock-Based Compensation

As of March 31, 2016, the Company had 15,928,072 options to purchase common stock outstanding.

At the Company’s Annual Meeting of the Stockholders held on June 10, 2013, the Company’s stockholders voted to approve the Rexahn Pharmaceuticals, Inc. 2013 Stock Option Plan (the “2013 Plan”).  Under the 2013 Plan, the Company grants stock options to key employees, directors and consultants of the Company.  A total of 17,000,000 shares of common stock have been reserved for issuance pursuant to the 2013 Plan.  As of March 31 2016, there were 10,129,572 options outstanding under the 2013 Plan, and 6,862,928 shares were available for issuance.

On August 5, 2003, the Company established a stock option plan (the “2003 Plan”).  Under the 2003 Plan, the Company granted stock options to key employees, directors and consultants of the Company.  With the adoption of the 2013 Plan, no new stock options may be issued under the 2003 Plan, but previously issued options under the 2003 Plan remain outstanding until their expiration.  As of March 31, 2016, there were 5,678,500 outstanding options under the 2003 Plan.

In March 2016, the Company granted to a third party an option to purchase up to 120,000 shares of the Company’s common stock.  Of the Company’s outstanding options as of March 31, 2016, these were the only options that were not issued pursuant to the 2013 Plan or the 2003 Plan.

For the majority of the grants to employees, the vesting period is either (i) 30%, 30% and 40% on the first, second and third anniversaries, of the grant date, respectively, or (ii) 25% each on the first four anniversaries.  With the exception of the options granted in March 2016, which have a three-year term, options expire between five and ten years from the date of grant. For the majority of grants to non-employee consultants of the Company, the vesting period is between one and three years, subject to the fulfillment of certain conditions in the individual stock agreements, or 100% upon the occurrence of certain events specified in the individual stock agreements.

Accounting for Awards

Stock option compensation expense is the estimated fair value of options granted amortized on a straight-line basis over the requisite vesting service period for the entire portion of the award. Total stock-based compensation recognized by the Company for the three months ended March 31, 2016 and 2015 is as follows:

   
For the Three Months Ended
March 31,
 
   
2016
   
2015
 
Statement of operations line item:
           
General and administrative
 
$
215,327
   
$
190,039
 
Research and development
   
127,684
     
82,347
 
                 
Total
 
$
343,011
   
$
272,386
 

No income tax benefit has been recognized in the statement of operations for stock-based compensation arrangements as the Company has provided for a 100% valuation allowance on its deferred tax assets.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

Summary of Stock Option Transactions

There were 3,337,090 stock options granted at exercise prices ranging from $0.35 to $0.37 with an aggregate fair value of $732,042 during the three months ended March 31, 2016.  There were 3,426,316 stock options granted at exercise prices ranging from $0.71 to $0.89 with an aggregate fair value of $1,698,737 during the three months ended March 31, 2015.

The fair value of options at the date of grant was estimated using the Black-Scholes option pricing model.  The Company took into consideration guidance under ASC 718, “Compensation-Stock Compensation” and Staff Accounting Bulletin No. 107 (“SAB 107”) when reviewing and updating assumptions.  The expected volatility is based upon historical volatility of the Company’s stock.  The expected term is based upon the simplified method as allowed under SAB 107.

The assumptions made in calculating the fair values of options are as follows:

   
Three Months Ended March 31,
 
   
2016
   
2015
 
Black-Scholes assumptions
           
Expected dividend yield
   
0
%
   
0
%
Expected volatility
   
32-75
%
   
79-80
%
Risk free interest rate
   
0.7-1.4
%
   
1.3-1.6
%
Expected term (in years)
 
2-6 years
   
6 years
 

The following table summarizes share-based transactions:

   
Number of
Options
   
Weighted
Average
 Exercise
 Price
 
Weighted Average Remaining
Contractual Term
 
Aggregate
 Intrinsic
Value
 
Outstanding, January 1, 2016
   
12,590,982
   
$
0.83
 
6.8 years
 
$
26,500
 
Granted
   
3,337,090
     
0.35
           
Exercised
   
-
     
-
           
Expired
   
-
     
-
           
Cancelled
   
-
     
-
           
                           
Outstanding, March 31, 2016
   
15,928,072
   
$
0.73
 
7.2 years
 
$
10,600
 
Exercisable, March 31, 2016
   
8,040,304
   
$
0.88
 
5.3 years
 
$
10,600
 

The total intrinsic value of the options exercised was $98,051 for the three months ended March 31, 2015.  There were no stock options exercised during the three months ended March 31, 2016.  The weighted average fair value of the options granted was $0.22 and $0.49 for the three months ended March 31, 2016 and 2015 respectively.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

A summary of the Company’s unvested options as of March 31, 2016 and changes during the three months ended March 31, 2016 is presented below:

   
2016
 
   
Number of Options
 
Weighted Average Fair
Value at Grant Date
 
Unvested at January 1, 2016
   
5,888,432
   
$
0.51
 
Granted
   
3,337,090
   
$
0.22
 
Vested
   
(1,337,754
)
 
$
0.50
 
Cancelled
   
-
   
$
-
 
                 
Unvested at March 31, 2016
   
7,887,768
   
$
0.39
 

As of March 31, 2016 there was $2,618,945 of total unrecognized compensation cost related to unvested stock options, which is expected to be recognized over a weighted average vesting period of 2.6 years.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

12.
Warrants

As of March 31, 2016, warrants to purchase 38,991,904 shares were outstanding, having exercise prices ranging from $0.40 to $1.50 and expiration dates ranging from July 5, 2016 to September 2, 2021.

   
2016
   
2015
 
   
Number of
warrants
 
Weighted
average exercise
price
   
Number of
warrants
 
Weighted average
 exercise price
 
Balance, January 1
   
26,491,904
   
$
0.80
     
13,205,871
   
$
1.07
 
Issued during the period
   
12,500,000
   
$
0.42
     
-
   
$
-
 
Exercised during the period
   
-
   
$
-
     
-
   
$
-
 
Expired during the period
   
-
   
$
-
     
-
   
$
-
 
                                 
Balance, March 31
   
38,991,904
   
$
0.68
     
13,205,871
   
$
1.07
 

At March 31, 2016 the weighted average remaining contractual life of the outstanding warrants was 4.1 years.

The warrants issued to investors in the March 2011, December 2012, November 2015 and March 2016 offerings contain a provision for net cash settlement in the event that there is a fundamental transaction (contractually defined as a merger, sale of substantially all assets, tender offer or share exchange).  If a fundamental transaction occurs in which the consideration issued consists principally of cash or stock in a non-public company, then the warrant holder has the option to receive cash, equal to the fair value of the remaining unexercised portion of the warrant.  Due to this contingent redemption provision, the warrants require liability classification in accordance with ASC 480 and are recorded at fair value.  The warrants issued to investors in the July 2013, October 2013 and January 2014 offerings contain a fundamental transaction provision, but the warrant holders only have an option as to the type of consideration received if the holders of common stock receive an option as to their consideration.  In addition, the warrants issued in the March 2011, December 2012, July 2013, October 2013, January 2014, November 2015 and March 2016 contain a cashless exercise provision that is exercisable only in the event that a registration statement is not effective. That provision may not be operative if an effective registration statement is not available because an exemption under the U.S. securities laws may not be available to issue unregistered shares.  As a result, net cash settlement may be required, and the warrants require liability classification.

ASC 820 provides requirements for disclosure of liabilities that are measured at fair value on a recurring basis in periods subsequent to the initial recognition.  Fair values for warrants were determined using the Binomial Lattice (“Lattice”) valuation technique. The Lattice model provides for dynamic assumptions regarding volatility and risk-free interest rates within the total period to maturity. Accordingly, within the contractual term, the Company provided multiple date intervals over which multiple volatilities and risk free interest rates were used. These intervals allow the Lattice model to project outcomes along specific paths that consider volatilities and risk free rates that would be more likely in an early exercise scenario.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

Significant assumptions are determined as follows:
Trading market values—Published trading market values;
Exercise price—Stated exercise price;
Term—Remaining contractual term of the warrant;
Volatility—Historical trading volatility for periods consistent with the remaining terms; and
Risk-free rate—Yields on zero coupon government securities with remaining terms consistent with the remaining terms of the warrants.

Due to the fundamental transaction provision, which could provide for early redemption of the warrants, the model also considered the probability the Company would enter into a fundamental transaction during the remaining term of the warrant. Because the Company is not yet achieving positive cash flow, management believes the probability of a fundamental transaction occurring over the term of the warrant is unlikely and therefore estimates the probability of entering into a fundamental transaction to be 5%.  For valuation purposes, the Company also assumed that if such a transaction did occur, it was more likely to occur towards the end of the term of the warrants.

The significant unobservable inputs used in the fair value measurement of the warrants include management’s estimate of the probability that a fundamental transaction may occur in the future.  Significant increases (decreases) in the probability of occurrence would result in a significantly higher (lower) fair value measurement.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

The following table summarizes the fair value of the warrants as of the respective balance sheet dates:

   
Fair Value as of:
 
Warrant Issuance:
 
March 31, 2016
   
December 31, 2015
 
March 31, 2011 financing:
           
Warrants to institutional investors
 
$
33
   
$
30
 
December 4, 2012 financing:
               
Warrants to institutional investors
   
8,451
     
9,818
 
Warrants to placement agent
   
529
     
1,206
 
July 26, 2013 financing:
               
Warrants to institutional investors
   
90,766
     
121,420
 
Warrants to placement agent
   
64
     
384
 
October 16, 2013 financing:
               
Warrants to institutional investors
   
142,908
     
169,349
 
Warrants to placement agent
   
145
     
970
 
January 21, 2014 financing:
               
Warrants to institutional investors
   
106,190
     
131,476
 
November 12, 2015 financing:
               
Warrants to institutional investors
   
1,840,663
     
2,169,375
 
Warrants to placement agent
   
113,251
     
135,135
 
March 2, 2016 financing:
               
Warrants to institutional investors
   
2,027,777
     
-
 
Warrants to placement agent
   
128,291
     
-
 
Total:
 
$
4,459,068
   
$
2,739,163
 
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

The following table summarizes the number of shares indexed to the warrants as of the respective balance sheet dates:

   
Number of Shares indexed as of:
 
Warrant Issuance
 
March 31, 2016
   
December 31, 2015
 
March 31, 2011 financing:
           
Warrants to institutional investors
   
3,333,333
     
3,333,333
 
December 4, 2012 financing:
               
Warrants to institutional investors
   
174,300
     
174,300
 
Warrants to placement agent
   
40,000
     
40,000
 
July 26, 2013 financing:
               
Warrants to institutional investors
   
2,000,000
     
2,000,000
 
Warrants to placement agent
   
124,032
     
124,032
 
October 16, 2013 financing:
               
Warrants to institutional investors
   
2,317,309
     
2,317,309
 
Warrants to placement agent
   
407,692
     
407,692
 
January 21, 2014 financing:
               
Warrants to institutional investors
   
4,761,905
     
4,761,905
 
November 12, 2015 financing:
               
Warrants to institutional investors
   
12,500,000
     
12,500,000
 
Warrants to placement agent
   
833,333
     
833,333
 
March 2, 2016 financing:
               
Warrants to institutional investors
   
11,718,750
     
-
 
Warrants to placement agent
   
781,250
     
-
 
Total:
   
38,991,904
     
26,491,904
 

The assumptions used in calculating the fair values of the warrants are as follows:

   
March 31, 2016
   
December 31, 2015
 
Trading market prices
 
$
0.33
   
$
0.36
 
Estimated future volatility
   
105
%
   
105
%
Dividend
   
-
     
-
 
Estimated future risk-free rate
   
0.23-1.70
%
   
0.82-2.38
%
Equivalent volatility
   
51-66
%
   
44-65
%
Equivalent risk-free rate
   
0.16-0.79
%
   
0.22-1.11
%
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

Changes in the fair value of the warrant liabilities, carried at fair value, as reported as “unrealized gain on fair value of warrants” in the statement of operations:

   
Three Months Ended March 31,
 
   
2016
   
2015
 
March 31, 2011 financing:
           
Warrants to institutional investors
   
(3
)
   
102,077
 
December 4, 2012 financing:
               
Warrants to institutional investors
   
1,368
     
(2,897
)
Warrants to placement agent
   
677
     
143
 
July 26, 2013 financing:
               
Warrants to institutional investors
   
30,654
     
(24,786
)
Warrants to placement agent
   
321
     
4,345
 
October 16, 2013 financing:
               
Warrants to institutional investors
   
26,440
     
(17,760
)
Warrants to placement agent
   
826
     
15,179
 
January 21, 2014 financing:
               
Warrants to institutional investors
   
25,286
     
39,114
 
November 12, 2015 financing:
               
Warrants to institutional investors
   
328,713
     
-
 
Warrants to placement agent
   
21,882
     
-
 
March 2, 2016 financing:
               
Warrants to institutional investors
   
392,145
     
-
 
Warrants to placement agent
   
27,646
     
-
 
Total:
 
$
855,955
   
$
115,415
 
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

13.
Income Taxes

No provision for federal and state income taxes was required for the three months ended March 31, 2016 and 2015 due to the Company’s operating losses and increased deferred tax asset valuation allowance.  At March 31, 2016 and December 31, 2015, the Company had unused net operating loss carry-forwards of approximately $103,588,000 and $98,954,000, respectively, which expire at various dates through 2036.  Some of this amount may be subject to annual limitations under certain provisions of the Internal Revenue Code related to “changes in ownership.”

As of March 31, 2016 and December 31, 2015, the deferred tax assets related to the aforementioned carry-forwards have been fully offset by valuation allowances, because significant utilization of such amounts is not presently expected in the foreseeable future.

Deferred tax assets and valuation allowances consist of:

    
March 31,
2016
   
December 31,
2015
 
             
Net Operating Loss Carryforwards
 
$
40,399,000
   
$
38,592,000
 
Stock Compensation Expense
   
2,020,000
     
1,891,000
 
Book tax differences on assets and liabilities
   
324,000
     
380,000
 
Valuation Allowance
   
(42,743,000
)
   
(40,863,000
)
                 
Net Deferred Tax Assets
 
$
-
   
$
-
 

The Company files income tax returns in the U.S. federal and Maryland state jurisdictions.  Tax years for fiscal 2012 through 2015 are open and potentially subject to examination by the federal and Maryland state taxing authorities.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

14.
Commitments and Contingencies

 
a)
The Company has contracted with various vendors for research and development services, the terms which require payments over the terms of the agreements, usually ranging from two to 36 months. The costs to be incurred are estimated and are subject to revision. As of March 31, 2016, the total estimated cost to complete these agreements was approximately $8,370,000.    All of these agreements may be terminated by either party upon appropriate notice as stipulated in the respective agreements.

 
b)
On June 22, 2009, the Company entered into a License Agreement with Korea Research Institute of Chemical Technology (“KRICT”) to acquire the rights to all intellectual property related to quinoxaline-piperazine derivatives that were synthesized under a Joint Research Agreement.  The initial license fee was $100,000, all of which was paid as of December 31, 2009.  The agreement with KRICT calls for a one-time milestone payment of $1,000,000 within 30 days after the first achievement of marketing approval of the first commercial product arising out of or in connection with the use of KRICT’s intellectual properties.  As of March 31, 2016, the milestone has not occurred.

 
c)
Office Space Lease

On June 7, 2013, the Company signed the first amendment to its commercial lease agreement for 5,466 square feet of office space in Rockville, Maryland.  The amendment extends the lease term until June 30, 2019.  Under the lease agreement, the Company pays its allocable portion of real estate taxes and common area operating charges.

On July 26, 2014 the Company entered into the second amendment to the lease agreement.  According to the terms of this amendment, the Company leased an additional 1,637 square feet of office space, beginning on September 1, 2014 and ending on August 31, 2015.  On May 6, 2015, the Company renewed the lease for this space for an additional year, beginning on September 1, 2015 and ending on August 31, 2016.

Rent paid under the Company’s lease during the three months ended March 31, 2016 and 2015 was $51,301 and $50,058, respectively.

Prior Laboratory Lease

On August 26, 2014, the Company signed a one-year renewal to use laboratory space commencing on July 1, 2014 and ending on June 30, 2015.  The lease required monthly rental payments of $4,554.  Rent paid under the Company’s lease during the three months ended March 31, 2015 was $13,662.

Current Laboratory Lease

On April 20, 2015, the Company signed a five-year lease agreement for 2,552 square feet of laboratory space commencing on July 1, 2015 and ending on June 30, 2020.  Under the lease agreement, the Company pays its allocable portion of real estate taxes and common area operating charges. Rent paid under this lease during the three months ended March 31, 2016 was $15,312.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

Future rental payments over the next five years for all leases are as follows:

For the remaining nine months ending December 31:
2016
   
203,120
 
For the year ending December 31:
2017
   
260,217
 
 
2018     
233,923
 
2019 
   
152,955
 
2020 
   
34,468
 
           
Total  
$
884,683
 

d) The Company has established a 401(k) plan for its employees.  The Company has elected to match 100% of the first 3% of an employee’s compensation plus 50% of an additional 2% of the employee’s deferral. Expense related to this matching contribution aggregated to $31,503 and $29,359 for the three months ended March 31, 2016 and 2015, respectively.

e) In July 2013, the Company entered into an exclusive license agreement with the University of Maryland, Baltimore for a novel drug delivery platform, Nano-Polymer Drug Conjugate Systems.  RX-21101 is the Company’s first drug candidate utilizing this platform.  The agreement requires the Company to make payments to the University of Maryland if RX-21101 or any products from the licensed delivery platform achieve development milestones.  As of March 31, 2016, no development milestones have occurred.

f) In October 2013, the Company signed an exclusive license agreement with the Ohio State Innovation Foundation, for a novel oligonucleotide drug delivery platform, Lipid-Coated Albumin Nanoparticle.  The agreement requires the Company to make payments to the Ohio State Innovation Foundation or any products from the licensed delivery platform achieve development milestones.  As of March 31, 2016, no development milestones have occurred.
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)
 
15.
Fair Value Measurements

ASC 820 defines fair value as the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date, not adjusted for transaction costs.  ASC 820 also establishes a fair value hierarchy that prioritizes the inputs to valuation techniques used to measure fair value into three broad levels giving the highest priority to quoted prices in active markets for identical assets or liabilities (Level 1) and the lowest priority to unobservable inputs (Level 3).

The three levels are described below:

Level 1 Inputs
Unadjusted quoted prices in active markets for identical assets or liabilities that are accessible by the Company;
     
Level 2 Inputs
Quoted prices in markets that are not active or financial instruments for which all significant inputs are observable, either directly or indirectly; and
     
Level 3 Inputs
Unobservable inputs for the asset or liability including significant assumptions of the Company and other market participants.

The following tables present assets and liabilities that are measured at fair value on a recurring basis and are categorized using the fair value hierarchy.  There have been no changes in the methodologies used at March 31, 2016 and December 31, 2015.
 
 
Fair Value Measurements at March 31, 2016
 
   
Total
   
Level 1
   
Level 2
   
Level 3
 
Assets:
                       
Certificates of Deposit
 
$
6,001,423
   
$
-
   
$
6,001,423
   
$
-
 
Commercial Paper
   
2,984,820
     
-
     
2,984,820
     
-
 
Corporate Bonds
   
5,018,930
     
-
     
5,018,930
     
-
 
Total Assets:
 
$
14,005,173
   
$
-
   
$
14,005,173
   
$
-
 
                                 
Liabilities:
                               
Warrant Liabilities
 
$
4,459,068
     
-
     
-
   
$
4,459,068
 


   
Fair Value Measurements at December 31, 2015
 
   
Total
   
Level 1
   
Level 2
   
Level 3
 
Assets:
                       
Certificates of Deposit
 
$
6,234,996
   
$
-
   
$
6,234,996
   
$
-
 
Commercial Paper
   
2,977,570
     
-
     
2,977,570
     
-
 
Corporate Bonds
   
4,027,520
     
-
     
4,027,520
     
-
 
Total Assets:
 
$
13,240,086
   
$
-
   
$
13,240,086
   
$
-
 
                                 
Liabilities:
                               
Warrant Liabilities
 
$
2,739,163
     
-
     
-
   
$
2,739,163
 
 
REXAHN PHARMACEUTICALS, INC.
Notes to Condensed Financial Statements
(Unaudited)

The fair value of the Company’s Level 2 marketable securities is determined by using quoted prices from independent pricing services that use market data for comparable securities in active or inactive markets.  A variety of data inputs, including benchmark yields, interest rates, known historical trades and broker dealer quotes are used with pricing models to determine the quoted prices.

The fair value methodology for the warrant liabilities is disclosed in Note 12.

The carrying amounts reported in the financial statements for cash and cash equivalents (Level 1), prepaid expenses, and other assets and accounts payable and accrued expenses approximate fair value because of the short term maturity of these financial instruments.

The following table sets forth a reconciliation of changes in the three months ended March 31, 2016 and 2015 in the fair value of the liabilities classified as Level 3 in the fair value hierarchy:

   
Warrant Liabilities
 
Balance at January 1, 2016
 
$
2,739,163
 
Additions
   
2,575,860
 
Unrealized gains, net
   
(855,955
)
Transfers out of level 3
   
-
 
Balance at March 31, 2016
 
$
4,459,068
 

   
Warrant Liabilities
 
Balance at January 1, 2015
 
$
3,768,351
 
Additions
   
-
 
Unrealized gains, net
   
(115,415
)
Transfers out of level 3
   
-
 
Balance at March 31, 2015
 
$
3,652,936
 

Additions consist of the fair value of warrant liabilities upon issuance.  Transfers out of Level 3 for warrant liabilities consist of warrant exercises, where the liability is converted to additional paid-in capital upon exercise.  The Company’s policy is to recognize transfers in and transfers out as of the actual date of the event or change in circumstance that caused the transfer. 
 
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.

OVERVIEW

The following discussion should be read in conjunction with the unaudited condensed financial statements and notes thereto set forth in Item 1 of this Quarterly Report on Form 10-Q and the audited financial statements and notes thereto included in our Annual Report on Form 10-K for the year ended December 31, 2015.

Except for the historical information contained herein, the matters discussed in this Quarterly Report on Form 10-Q may be deemed to be forward-looking statements that involve risks and uncertainties.  We make such forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and other federal securities laws.  In this Quarterly Report on Form 10-Q, words such as “believe,” “estimate,” “expect,” “anticipate,” “will,” “may,” “intend” and other similar expressions, are intended to identify forward-looking statements.  We caution that forward-looking statements are based largely on our expectations and are subject to a number of known and unknown risks and uncertainties that are subject to change based on factors that are, in many instances, beyond our control.  Actual results, performance or achievements may differ materially from those contemplated, expressed or implied by the forward-looking statements.

Although we believe that the expectations reflected in our forward-looking statements are reasonable as of the date we make them, actual results could differ materially from those currently anticipated due to a number of factors, including risks relating to:

· our understandings and beliefs regarding the role of certain biological mechanisms and processes in cancer;

· our drug candidates being in early stages of development, including in pre-clinical development;

· our ability to initially develop drug candidates for orphan indications to reduce the time-to-market and take advantage of certain incentives provided by the U.S. Food and Drug Administration;

· our ability to transition from our initial focus on developing drug candidates for orphan indications to candidates for more highly prevalent indications;

· our ability to successfully and timely complete clinical trials for our drug candidates in clinical development;

· uncertainties related to the timing, results and analyses related to our drug candidates in pre-clinical development;

· our ability to obtain the necessary U.S. and international regulatory approvals for our drug candidates;

· our reliance on third-party contract research organizations and other investigators and collaborators for certain research and development services;

· our ability to maintain or engage third-party manufacturers to manufacture, supply, store and distribute supplies of our drug candidates for our clinical trials;
 
· our ability to form strategic alliances and partnerships with pharmaceutical companies and other partners for sales and marketing of certain of our product candidates;

· demand for and market acceptance of our drug candidates;

· the scope and validity of our intellectual property protection for our drug candidates and our ability to develop our candidates without infringing the intellectual property rights of others;

· our lack of profitability and the need for additional capital to operate our business; and

· other risks and uncertainties, including those set forth herein and in our Annual Report on Form 10-K under the caption “Risk Factors” and those detailed from time to time in our filings with the Securities and Exchange Commission.

These forward-looking statements are made only as of the date hereof, and we undertake no obligation to update or revise the forward-looking statements, whether as a result of new information, future events or otherwise.

We are a clinical stage biopharmaceutical company dedicated to the discovery, development and commercialization of innovative treatments for cancer. Our mission is to improve the lives of cancer patients by developing next-generation cancer therapies that are designed to maximize efficacy while minimizing the toxicity and side effects traditionally associated with cancer treatment. Our clinical pipeline features one product candidate in Phase II clinical development, one product candidate in Phase Ib/IIa clinical development, one product candidate in Phase I clinical development and additional compounds in pre-clinical development. Our strategy is to continue building a significant pipeline of innovative oncology product candidates that we will commercialize alone or with partners. Our three clinical stage drug candidates in active development are Archexin®, RX-3117 and SupinoxinTM (RX-5902).

· Archexin is a potential best-in-class, potent inhibitor of the protein kinase Akt-1, which we believe plays a critical role in cancer cell proliferation, survival, angiogenesis, metastasis and drug resistance. Archexin has received “orphan drug” designation from the U.S. Food and Drug Administration (the “FDA”) for renal cell carcinoma (“RCC”), glioblastoma, ovarian cancer, stomach cancer and pancreatic cancer. Orphan drug designation provides tax incentives for clinical research and a waiver from user fees under certain circumstances. In addition, an orphan drug receives seven years of exclusivity after approval, during which the FDA generally cannot approve another product with the same active moiety for the same indication. We have completed a pilot Phase IIa clinical trial of Archexin for the treatment of pancreatic cancer. We are currently conducting a Phase IIa proof-of-concept clinical trial of Archexin in patients with metastatic renal cell carcinoma to evaluate its safety and efficacy.

· RX-3117 is a small molecule nucleoside compound with an anti-metabolite mechanism of action, and we believe it has therapeutic potential in a broad range of cancers, including pancreatic, bladder, colon, and lung cancer. We completed an exploratory Phase I clinical study of RX-3117 that showed a level of oral bioavailability of RX-3117 in humans with no adverse effects reported.  We recently identified the maximum tolerated dose (“MTD”) of RX-3117, which we are now evaluating in a Phase Ib/IIa proof-of-concept clinical trial in patients with relapsed and refractory pancreatic cancer and advanced bladder cancer.
 
· Supinoxin, or RX-5902, is a potential first-in-class small molecule inhibitor of phosphorylated-p68, a protein that we believe plays a key role in cancer cell growth, progression and metastasis. We are currently conducting a Phase I clinical trial of Supinoxin to evaluate its safety and efficacy in patients with solid tumors.

Since our inception, our efforts and resources have been focused primarily on developing our pharmaceutical technologies, raising capital and recruiting personnel.  We have no product sales to date, and we will not generate any product sales until we receive approval from the FDA or equivalent foreign regulatory bodies to begin selling our pharmaceutical candidates.  Our major sources of working capital have been proceeds from various private and public financings, and licensing and collaboration agreements with our strategic investors and partners.

Recently Issued Accounting Standards

See Note 2, “Recent Accounting Pronouncements Affecting the Company”, in the Notes to Condensed Financial Statements for a discussion of recent accounting pronouncements.

Results of Operations

Comparison of the Three Months Ended March 31, 2016 and March 31, 2015

Total Revenues

We had no revenues for the three months ended March 31, 2016 or 2015.

General and Administrative Expenses

General and administrative expenses consist primarily of salaries and related expenses for executive, finance and other administrative personnel, recruitment expenses, professional fees and other corporate expenses, including business development, investor relations, and general legal activities.

General and administrative expenses decreased $129,294, or 8.5%, to $1,395,406 for the three months ended March 31, 2016 from $1,524,700 for the three months ended March 31, 2015.  The decrease is primarily attributable to higher personnel and recruiting costs in 2015.

Research and Development Expenses

Research and development expenses increased $575,567, or 19.9%, to $3,468,575 for the three months ended March 31, 2016, from $2,893,008 for the three months ended March 31, 2015.  The increase is primarily attributable to the advancement of our drug candidates, as we incurred additional clinical trial and drug manufacturing costs related to our clinical trials for Archexin and Supinoxin, which were partially offset by a decrease in drug manufacturing costs for RX-3117.  The increase is also partially attributable to an increase in personnel expenses.
 
The table below summarizes the approximate amounts incurred on each of our research and development projects for the three months ended March 31, 2016 and 2015:

   
For the Three Months Ended March 31,
 
   
2016
   
2015
 
Clinical Candidates:
           
Archexin
 
$
857,600
   
$
502,400
 
RX-3117
   
947,200
     
1,169,700
 
Supinoxin
   
736,100
     
386,600
 
                 
Preclinical, Personnel and Overhead
   
927,675
     
834,308
 
                 
Total Research and Development Expenses
 
$
3,468,575
   
$
2,893,008
 

Interest Income

Interest income decreased $1,711 or 5.6% to $28,871 for the three months ended March 31, 2016 from $30,582 for the three months ended March 31, 2015.  The decrease is primarily attributable to lower aggregate balances of cash, cash equivalents, and marketable securities for the three months ended March 31, 2016 compared to the three months ended March 31, 2015.

Unrealized Gain on Fair Value of Warrants

Our warrants are recorded as liabilities at fair value, and the warrants are valued using a lattice model.  Changes in the fair value of warrants are recorded as an unrealized gain or loss in our statement of operations.  During the three months ended March 31, 2016 and 2015, we recorded unrealized gains  on the fair value of our warrants of $855,955 and $115,415 respectively.  Estimating fair values of warrants requires the development of significant and subjective estimates that may, and are likely to, change over the duration of the warrants due to related changes to external market factors. The unrealized gains for the three months ended March 31, 2016 primarily resulted from a decreased price of the underlying common stock at March 31, 2016 and an increase in the number of outstanding warrants.

Financing Expense

We incurred $169,887 of financing expenses during the three months ended March 31, 2016 related to our registered direct offering in March 2016.

Net Loss

As a result of the above, net loss for the three months ended March 31, 2016 and 2015 was $4,149,042 and $4,271,711 or $0.02 per share for each period.
 
Research and Development Projects

Research and development costs are expensed as incurred.  These costs consist primarily of salaries and related personnel costs, costs to acquire pharmaceutical products and product rights for development and amounts paid to contract research organizations, hospitals and laboratories for the provision of services and materials for drug development and clinical trials.  Costs incurred in obtaining the license rights to technology in the research and development stage that have no alternative future uses are expensed as incurred.  Our research and development programs are related to our oncology clinical stage drug candidates, Archexin, RX-3117 and Supinoxin, and our pre-clinical stage drug candidate, RX-21101.  As we expand our clinical studies, we expect to enter into additional development agreements.  Significant additional expenditures will be required if we complete our clinical trials, start new trials, apply for regulatory approvals, continue development of our technologies, expand our operations and bring our products to market.  The eventual total cost of each clinical trial is dependent on a number of uncertainties such as trial design, the length of the trial, the number of clinical sites and the number of patients.  The process of obtaining and maintaining regulatory approvals for new therapeutic products is lengthy, expensive and uncertain.  Because the successful development of our most advanced drug candidates, Archexin, RX-3117 and Supinoxin, is uncertain, and because RX-21101 is in early-stage development, we are unable to estimate the costs of completing our research and development programs, the timing of bringing such programs to market and, therefore, when material cash inflows could commence from the sale of these drug candidates, if any.  If these projects are not completed as planned, our results of operations and financial condition would be negatively affected.

Archexin

Archexin is a potential best-in-class, potent inhibitor of the protein kinase Akt-1, which we believe plays a critical role in cancer cell proliferation, survival, angiogenesis, metastasis and drug resistance.  We are currently conducting a Phase IIa proof-of-concept clinical trial of Archexin in patients with metastatic RCC to evaluate its safety and efficacy.  The trial is being conducted in two stages.  Stage 1, which we completed in January 2016, was a dose ranging study, with up to three dose groups with three RCC patients each, to determine Archexin’s MTD in combination with everolimus.  Stage 2, which commenced in January 2016, is a randomized, open-label, two-arm dose expansion study of everolimus versus Archexin in combination with everolimus to determine safety and efficacy of the combination.  Stage 2 is anticipated to enroll up to 30 RCC patients who will be randomized to receive either Archexin in combination with everolimus, or everolimus alone, in a ratio of 2:1 The MTD of 250 mg/m2/day of Archexin, which was identified in Stage 1, will be administered in Stage 2 along with 10 mg of everolimus compared to 10 mg everolimus alone.

Expenses related to Archexin increased during the three months ended March 31, 2016 compared to the three months ended March 31, 2015 due to patient enrollment and drug manufacturing costs. We expect that expenses related to Archexin will continue to increase for the remainder of 2016 compared to 2015 as we continue Stage 2 of the ongoing Archexin clinical trial.

RX-3117

 RX-3117 is a novel, investigational oral small molecule nucleoside compound.  We believe RX-3117 has therapeutic potential in a broad range of cancers including pancreatic, bladder, cervical, non-small cell lung cancer and colon cancer.  During the quarter ended March 31, 2016, we identified the MTD of RX-3117, which we are now evaluating in a Phase Ib/IIa proof-of-concept clinical trial in patients with relapsed and refractory pancreatic cancer and advanced bladder cancer.
 
Expenses related to RX-3117 decreased during the three months ended March 31, 2016 compared to the same period in 2015 as we incurred greater drug manufacturing costs during the three months ended March 31, 2015 for our Phase I and Phase Ib/IIa trials.  However, we expect expenses will increase in the remainder of 2016 compared to 2015 due to patient enrollment costs.

Supinoxin (RX-5902)

Supinoxin is a potential first-in-class small molecule inhibitor of phosphorylated p68, a protein that we believe plays a key role in cancer growth, progression and metastasis. Phosphorylated p68 results in up-regulation of cancer-related genes and a subsequent proliferation of cancer cells and tumor growth.  Supinoxin is currently being evaluated in a Phase I dose-escalation clinical trial in cancer patients with solid tumors designed to evaluate its safety, tolerability, dose-limiting toxicities and MTD. Secondary endpoints include pharmacokinetic analyses and an evaluation of the preliminary anti-tumor effects of Supinoxin.   We plan to commence a Phase Ib/IIa clinical study to evaluate the safety and efficacy of Supinoxin in patients with triple negative breast cancer and relapsed/refractory ovarian cancer.

Expenses related to Supinoxin increased during the three months ended March 31, 2016 compared to the three months ended March 31, 2015 due to patient enrollment and drug manufacturing costs.  We expect that expenses related to Supinoxin will continue to increase in the remainder of 2016 compared to 2015 as we expect to reach the MTD/recommended Phase Ib/IIa dose in mid-2016 and expect to continue development with our planned Phase Ib/IIa study.

Pre-clinical Pipeline

Expenses related to our pre-clinical candidates remained flat for the three months ended March 31, 2016 compared to the same period in 2015.  We expect that expenses related to our pre-clinical pipeline, including RX-21101, will continue to remain flat in 2016 compared to 2015 as we continue testing and development.

Research and Development Process

We have engaged third-party contract research organizations and other investigators and collaborators, such as universities and medical institutions, to conduct our pre-clinical studies, toxicology studies and clinical trials.  Engaging third-party contract research organizations is typical practice in our industry. However, relying on such organizations means that the clinical trials and other studies described above are being conducted at external locations and that the completion of these trials and studies is not within our direct control. Trials and studies may be delayed due to circumstances outside our control, and such delays may result in additional expenses for us.

Liquidity and Capital Resources

Cash Flows

Cash used in operating activities was $3,549,617 for the three months ended March 31, 2016.  The operating cash flows during the three months ended March 31, 2016 reflect our net loss of $4,149,042 and a net increase of cash components of working capital and non-cash charges totaling $599,425.  Cash used in operating activities was $4,038,817 for the three months ended March 31, 2015.  The operating cash flows during the three months ended March 31, 2015 reflect our net loss of $4,271,711, and a net increase of cash components of working capital and other non-cash charges totaling $232,894.
 
Cash used in investing activities was $766,356 for the three months ended March 31, 2016, which consisted of $1,721,960 and $4,596 for the purchases of marketable securities and equipment, respectively, offset by $960,000 from the redemption of marketable securities. Cash provided by investing activities was $4,236,240 for the three months ended March 31, 2015, which consisted of $4,985,000 from the redemption of marketable securities, offset by $740,825 and $7,935 for the purchases of marketable securities and equipment, respectively.

Cash provided by financing activities was $4,580,187 for the three months ended March 31, 2016, which consisted of net proceeds from our registered direct public offering in March, 2016.  Cash provided by financing activities was $705,542 for the three months ended March 31, 2015, which consisted of proceeds from the exercise of stock options.

At Market Issuance Sales Agreement

On March 16, 2015, we entered into an at market issuance sales agreement (the “Sales Agreement”) with MLV & Co. LLC (“MLV”), pursuant to which we may issue and sell shares of our common stock having an aggregate offering price of up to $40 million from time to time, at our option, through MLV as our sales agent, subject to certain terms and conditions. During the quarter ended March 31, 2016, we did not sell any shares of common stock pursuant to the Sales Agreement. Pursuant to the securities purchase agreement entered into in connection with our registered direct offering in March 2016, we are prohibited from selling shares under the Sales Agreement and from entering into an agreement to effect any issuance involving a variable rate transaction until March 2, 2017. Variable rate transactions generally include issuances of securities whose conversion or exercise prices may vary with the trading price of our common stock, securities with conversion or exercise prices that have reset mechanisms, and agreements whereby we may issue securities at a future determined price.

Contractual Obligations

We have a variety of contractual obligations, as more fully described in our 2015 Form 10-K.  These obligations include, but are not limited to, contractual obligations in connection with license agreements (including related milestone payments), lease payments, employee compensation and incentive program expenses, and contracts with various vendors for research and development services.  As of March 31, 2016, the total estimated cost to complete our contracts with vendors for research and development services was approximately $8,370,000 under the terms of the applicable agreements.  All of these agreements may be terminated by either party upon appropriate notice as stipulated in the respective agreements.

Current and Future Financing Needs

We have incurred negative cash flow from operations since we started our business.  We have spent, and expect to continue to spend, substantial amounts in connection with implementing our business strategy, including our planned product development efforts, our clinical trials and our research and development efforts.  We will need to raise additional capital through public or private equity or debt offerings or through arrangements with strategic partners or other sources in order to continue to develop our drug candidates.  There can be no assurance that additional capital will be available when needed or on terms satisfactory to us, if at all.  If we are not able to raise sufficient additional capital, we will have to reduce our research and development activities. We believe our cash, cash equivalents, and marketable securities will be sufficient to cover our cash flow requirements for our current activities for at least the next 12 months.
 
The actual amount of funds we will need to operate is subject to many factors, some of which are beyond our control.  These factors include the following:

· the progress of our product development activities;

· the number and scope of our product development programs;

· the progress of our pre-clinical and clinical trial activities;

· the progress of the development efforts of parties with whom we have entered into collaboration agreements;

· our ability to maintain current collaboration programs and to establish new collaboration arrangements;

· the costs involved in prosecuting and enforcing patent claims and other intellectual property rights; and

· the costs and timing of regulatory approvals.

Off-Balance Sheet Arrangements

We do not have any off-balance sheet arrangements or holdings in variable interest entities.
 
Item 3. Quantitative and Qualitative Disclosures About Market Risk.

For quantitative and qualitative disclosures about market risk, refer to “Quantitative and Qualitative Disclosures About Market Risk” in our 2015 Form 10-K.  Our exposures to market risk have not changed materially since December 31, 2015.

Item 4. Controls and Procedures.

Disclosure Controls and Procedures

Under the supervision and with the participation of our management, including our Chief Executive Officer (“CEO”) and Chief Financial Officer (“CFO”), we evaluated the effectiveness of the design and operation of our disclosure controls and procedures (as defined in Rule 13a-15(e) under the Exchange Act) as of the end of the period covered by this report. Based upon that evaluation, our CEO and CFO concluded that our disclosure controls and procedures as of the end of the period covered by this report were effective such that the information required to be disclosed by us in reports filed under the Exchange Act is (i) recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms and (ii) accumulated and communicated to our management, including our CEO and CFO, as appropriate to allow timely decisions regarding disclosure. A controls system cannot provide absolute assurance, however, that the objectives of the controls system are met, and no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within a company have been detected.

Changes in Internal Control Over Financial Reporting

There has been no change in our internal control over financial reporting (as such term is defined in Rule 13a-15(f) under the Exchange Act) during the quarter ended March 31, 2016 that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.
 
PART II. Other Information

Item 1A. Risk Factors.

Investing in our stock involves a high degree of risk.  In addition to the other information set forth in this report, you should carefully consider the factors set forth in the Risk Factors section of our 2015 Form 10-K, as well as other information contained in the 2015 Form 10-K and in other reports we file with the SEC. We do not believe that there have been any material changes to the risk factors disclosed in our 2015 Form 10-K.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds.

Pursuant to consulting agreements, we issued 135,000 shares of common stock during the three months ended March 31, 2016 to two privately held investor relations firms in consideration for investor relations services.  The shares of common stock were not registered under the Securities Act of 1933, as amended (the “Securities Act”) pursuant to the exemption from registration requirements provided by Section 4(a)(2) of the Securities Act, as transactions not involving a public offering.

On March 1, 2016, we entered into an agreement with a third investor relations firm pursuant to which we agreed to grant the investor relations firm options to purchase up to 120,000 shares of our common stock in consideration for investor relations services. The options granted pursuant to the agreement will have a three year term and will vest and become exercisable, subject to the continued service of the investor relations firm, 25% on the grant date, 25% on the three-month anniversary of the grant date, 25% on the six-month anniversary of the grant date and 25% on the nine-month anniversary of the grant date. The options and the underlying shares of common stock were not registered under the Securities Act pursuant to the exemption from registration requirements provided by Section 4(a)(2) thereof, as a transaction not involving a public offering.

Item 6. Exhibits.

The exhibits filed as part of this Quarterly Report on Form 10-Q are set forth on the Exhibit Index, which is incorporated herein by reference.
 
SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

   
REXAHN PHARMACEUTICALS, INC.
   
(Registrant)
     
 
By:
/s/ Peter D. Suzdak
Date: May 6, 2016
 
Peter D. Suzdak
   
Chief Executive Officer
   
(principal executive officer)
     
 
By:
/s/ Tae Heum Jeong
Date: May 6, 2016
 
Tae Heum Jeong
   
Chief Financial Officer and Secretary
   
(principal financial and accounting officer)
 
EXHIBIT INDEX
 
Exhibit No.
Description
 
 
4.1
Form of Warrant for Company’s Common Stock Purchase Warrants, filed as Exhibit 4.1 to the Company’s Current Report on Form 8-K filed on February 26, 2016, is incorporated herein by reference.
 
 
10.1
Form of Securities Purchase Agreement, dated as of February 26, 2016, by and between Rexahn Pharmaceuticals, Inc. and the purchasers identified on the signature pages thereto, filed as Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on February 26, 2016, is incorporated herein by reference.
 
 
Certification of Chief Executive Officer pursuant to Rules 13a-14(a) / 15d-14(a)
 
 
Certification of Chief Financial Officer pursuant to Rules 13a-14(a) / 15d-14(a)
 
 
Certification of Chief Executive Officer pursuant to 18 U.S.C. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
   
Certification of Chief Financial Officer pursuant to 18 U.S.C. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
   
101
The following materials from Rexahn Pharmaceuticals, Inc.’s Quarterly Report on Form 10-Q, formatted in Extensible Business Reporting Language (“XBRL”): (i) Condensed Balance Sheet; (ii) Condensed Statement of Operations; (iii) Condensed Statement of Comprehensive Loss; (iv) Condensed Statement of Cash Flows; and (v) Notes to the Financial Statements.

 


Exhibit 31.1
 
CERTIFICATION PURSUANT TO RULES 13A-14(D)
AND 15D-14(D)

I,     Peter D. Suzdak, certify that:

1.
I have reviewed this Quarterly Report on Form 10-Q of Rexahn Pharmaceuticals, Inc.;
2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;
3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;
4. The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
a. Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;
b. Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;
c. Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and
d. Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
5. The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):
a. All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and
b. Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Dated:  May 6, 2016
 
/s/ Peter D. Suzdak
 
Peter D. Suzdak
 
Chief Executive Officer
 
 



Exhibit 31.2

CERTIFICATION PURSUANT TO RULES 13A-14(D)
AND 15D-14(D)

I,     Tae Heum Jeong, certify that:

1.
I have reviewed this Quarterly Report on Form 10-Q of Rexahn Pharmaceuticals, Inc.;
2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;
3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;
4. The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
a. Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;
b. Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;
c. Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and
d. Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
5. The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):
a. All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and
b. Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Dated:  May 6, 2016
/s/ Tae Heum Jeong
Tae Heum Jeong
Chief Financial Officer
 
 


Exhibit 32.1

CERTIFICATION OF
CHIEF EXECUTIVE OFFICER
PURSUANT TO
18 U.S.C. SECTION 1350

SECTION 1350 CERTIFICATION*

In connection with the Quarterly Report of Rexahn Pharmaceuticals, Inc. (the “Company”) on Form 10-Q for the quarter ended March 31, 2016 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Peter D. Suzdak, Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that, to the best of my knowledge:

  (1) The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

  (2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Dated: May 6, 2016
By:
/s/ Peter D. Suzdak
 
   
Peter D. Suzdak,
 
   
Chief Executive Officer
 

*
This Certification is being furnished as required by Rule 13a-14(b) under the Securities Exchange Act of 1934 (the “Exchange Act”) and Section 1350 of Chapter 63 of Title 18 of the United States Code, and shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liability of that section. This Certification shall not be deemed to be incorporated by reference into any filing under the Securities Act of 1933 or the Exchange Act, except as otherwise stated in such filing.

A signed original of this written statement required by 18 U.S.C. § 1350 has been provided to the Company and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.
 



Exhibit 32.2

CERTIFICATION OF
CHIEF FINANCIAL OFFICER
PURSUANT TO
18 U.S.C. SECTION 1350

SECTION 1350 CERTIFICATION*

In connection with the Quarterly Report of Rexahn Pharmaceuticals, Inc. (the “Company”) on Form 10-Q for the quarter ended March 31, 2016 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Tae Heum Jeong, Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that, to the best of my knowledge:

  (1) The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

  (2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Dated: May 6, 2016
By:
/s/ Tae Heum Jeong
 
   
Tae Heum Jeong,
 
   
Chief Financial Officer
 

*
This Certification is being furnished as required by Rule 13a-14(b) under the Securities Exchange Act of 1934 (the “Exchange Act”) and Section 1350 of Chapter 63 of Title 18 of the United States Code, and shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liability of that section. This Certification shall not be deemed to be incorporated by reference into any filing under the Securities Act of 1933 or the Exchange Act, except as otherwise stated in such filing.

A signed original of this written statement required by 18 U.S.C. § 1350 has been provided to the Company and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.
 
 

v3.4.0.3
Document and Entity Information - shares
3 Months Ended
Mar. 31, 2016
May. 06, 2016
Document And Entity Information [Abstract]    
Document Type 10-Q  
Amendment Flag false  
Document Period End Date Mar. 31, 2016  
Entity Registrant Name REXAHN PHARMACEUTICALS, INC.  
Entity Central Index Key 0001228627  
Current Fiscal Year End Date --12-31  
Entity Filer Category Accelerated Filer  
Document Fiscal Year Focus 2016  
Document Fiscal Period Focus Q1  
Trading Symbol rnn  
Entity Common Stock, Shares Outstanding   213,173,785
v3.4.0.3
Condensed Balance Sheet - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Current Assets:    
Cash and cash equivalents $ 10,463,654 $ 10,199,440
Marketable securities 14,005,173 13,240,086
Prepaid expenses and other current assets 946,061 1,221,818
Total Current Assets 25,414,888 24,661,344
Security Deposits 30,785 30,785
Equipment, Net 111,335 112,900
Total Assets 25,557,008 24,805,029
Current Liabilities:    
Accounts payable and accrued expenses 3,284,267 2,661,298
Deferred Research and Development Arrangement 506,250 525,000
Other Liabilities 98,308 104,020
Warrant Liabilities 4,459,068 2,739,163
Total Liabilities $ 8,347,893 $ 6,029,481
Commitments and Contingencies (note 14)
Stockholders' Equity:    
Preferred stock, par value $0.0001, 100,000,000 authorized shares, none issued and outstanding
Common stock, par value $0.0001, 500,000,000 authorized shares, 213,173,785 and 197,413,785 issued and outstanding $ 21,317 $ 19,741
Additional paid-in capital 127,055,110 124,490,712
Accumulated other comprehensive loss (1,406) (18,041)
Accumulated deficit (109,865,906) (105,716,864)
Total Stockholders' Equity 17,209,115 18,775,548
Total Liabilities and Stockholders' Equity $ 25,557,008 $ 24,805,029
v3.4.0.3
Condensed Balance Sheet (Parenthetical) - $ / shares
Mar. 31, 2016
Dec. 31, 2015
Condensed Balance Sheet [Abstract]    
Preferred Stock, Par or Stated Value Per Share $ 0.0001 $ 0.0001
Preferred Stock, Shares Authorized 100,000,000 100,000,000
Preferred Stock, Shares Issued 0 0
Preferred Stock, Shares Outstanding 0 0
Common Stock, Par or Stated Value Per Share $ 0.0001 $ 0.0001
Common Stock, Shares Authorized 500,000,000 500,000,000
Common Stock, Shares, Issued 213,173,785 197,413,785
Common Stock, Shares, Outstanding 213,173,785 197,413,785
v3.4.0.3
Condensed Statement Of Operations - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Condensed Statement Of Operations    
Revenues
Expenses:    
General and administrative $ 1,395,406 $ 1,524,700
Research and development 3,468,575 2,893,008
Total Expenses 4,863,981 4,417,708
Loss from Operations (4,863,981) (4,417,708)
Other Income (Expense)    
Interest income 28,871 30,582
Unrealized gain on fair value of warrants 855,955 115,415
Financing expense (169,887)  
Total Other Income (Expense) 714,939 145,997
Net Loss Before Provision for Income Taxes $ (4,149,042) $ (4,271,711)
Provision for income taxes
Net Loss $ (4,149,042) $ (4,271,711)
Net loss per share, basic and diluted $ (0.02) $ (0.02)
Weighted average number of shares outstanding, basic and diluted 202,586,807 179,097,897
v3.4.0.3
Condensed Statement Of Comprehensive Loss - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Condensed Statement Of Comprehensive Loss [Abstract]    
Net Loss $ (4,149,042) $ (4,271,711)
Unrealized gain on available-for-sale securities 16,635 34,723
Comprehensive Loss $ (4,132,407) $ (4,236,988)
v3.4.0.3
Condensed Statement Of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Cash Flows from Operating Activities:    
Net Loss $ (4,149,042) $ (4,271,711)
Adjustments to reconcile net loss to net cash used in operating activities:    
Compensatory stock 48,749 56,250
Depreciation and amortization 6,161 6,165
Amortization of premiums and discounts on marketable securities, net 13,308 6,778
Stock-based compensation 343,011 272,386
Amortization of deferred research and development arrangements (18,750) (18,750)
Unrealized (gain) loss on fair value of warrants (855,955) (115,415)
Financing expense 169,887  
Amortization of deferred lease incentive (3,111) (3,111)
Deferred lease expenses (2,601) (1,645)
Changes in assets and liabilities:    
Prepaid expenses and other assets 275,757 (260,040)
Accounts payable and accrued expenses 622,969 290,276
Net Cash Used in Operating Activities (3,549,617) (4,038,817)
Cash Flows from Investing Activities:    
Purchase of equipment (4,596) (7,935)
Purchase of marketable securities (1,721,760) (740,825)
Redemption of marketable securities 960,000 4,985,000
Net Cash (Used In) Provided by Investing Activities (766,356) 4,236,240
Cash Flows from Financing Activities:    
Issuance of common stock and units, net of issuance costs 4,580,187  
Proceeds from exercise of stock options   705,542
Net Cash Provided by Financing Activities 4,580,187 705,542
Net Increase in Cash and Cash Equivalents 264,214 902,965
Cash and Cash Equivalents - beginning of period 10,199,440 9,826,245
Cash and Cash Equivalents - end of period 10,463,654 $ 10,729,210
Non-cash financing and investing activties:    
Warrants issued $ 2,575,860  
v3.4.0.3
Operations And Organization
3 Months Ended
Mar. 31, 2016
Operations And Organization [Abstract]  
Operations And Organization

1.Operations and Organization

Operations

Rexahn Pharmaceuticals, Inc. (the “Company,”), a Delaware corporation, is a biopharmaceutical company whose principal operations are the discovery, development and commercialization of innovative treatments for cancer.  The Company had an accumulated deficit of $109,865,906 at March 31, 2016 and anticipates incurring losses through fiscal year 2016 and beyond.  The Company has not yet generated commercial revenues and has funded its operating losses to date through the sale of shares of its common stock and warrants to purchase shares of its common stock, convertible debt, financings, interest income from cash, cash equivalents and marketable securities, and proceeds from reimbursed research and development costs.  The Company believes that its cash, cash equivalents, and marketable securities, will be sufficient to cover its cash flow requirements for its current activities for at least the next 12 months.  Management believes it has the capability of managing the Company’s operations within existing cash available by focusing on select research and development activities, selecting projects in conjunction with potential financings and milestones, and efficiently managing its general and administrative affairs.



Basis of Presentation

The accompanying unaudited condensed financial statements of the Company have been prepared pursuant to the rules and regulations of the U.S. Securities and Exchange Commission for interim financial information.  Accordingly, they do not include all of the information and footnotes required by accounting principles generally accepted in the United States (“U.S. GAAP”) for complete financial statements.  In the opinion of the Company’s management, all adjustments (consisting of only normal recurring accruals) considered necessary for a fair presentation of the Company’s financial position as of March 31, 2016 and December 31, 2015 and of the results of operations, comprehensive loss and cash flows for the three months ended March 31, 2016 and 2015 have been included.  Operating results for the three months ended March 31, 2016 are not necessarily indicative of results that may be expected for any other interim period or the full fiscal year ending December 31, 2016. The accompanying unaudited condensed financial statements should be read in conjunction with the audited financial statements and notes thereto included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2015 (the “2015 Form 10-K”).  Information included in the condensed balance sheet as of December 31, 2015 has been derived from the Company’s audited financial statements for the year ended December 31, 2015 included in the 2015 Form 10-K.



Use of Estimates

The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period.  These estimates are based on management’s best knowledge of current events and actions the Company may undertake in the future.  Actual results may ultimately differ from these estimates.  These estimates are reviewed periodically, and as adjustments become necessary, they are reported in earnings in the period in which they become available.



.  



v3.4.0.3
Recent Accounting Pronouncements Affecting The Company
3 Months Ended
Mar. 31, 2016
Recent Accounting Pronouncements Affecting The Company [Abstract]  
Recent Accounting Pronouncements Affecting The Company

2. Recent Accounting Pronouncements Affecting the Company

 

Revenue from Contracts with Customers



In May 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) 2014-09, “Revenue from Contracts with Customers,” a comprehensive new revenue recognition standard that will supersede nearly all existing revenue recognition guidance under U.S. GAAP. The standard’s core principle is that a company should recognize revenue when it transfers goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for those goods and services, and provides a revenue recognition framework in accordance with this principle.  On August 12, 2015, the FASB issued ASU 2015-14, which defers the effective date of ASU 2014-09 by one year to December 15, 2017 for annual reporting periods beginning after that date and interim periods therein.  Early adoption of the standard is permitted, but not before the original effective date of December 15, 2016.  The Company is currently evaluating the impact that the adoption of this guidance will have on its financial statements and future operating results.



Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern



In August 2014, the FASB issued ASU 2014-15, “Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern,” which requires management to perform interim and annual assessments as to the entity’s ability to continue as a going concern and provides related disclosure guidance.  ASU 2014-15 will be effective for reporting periods beginning after December 15, 2016, with early adoption permitted. The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.



Leases



In February 2016, the FASB issued ASU 2016-02, “Leases,” which requires an entity to recognize assets and liabilities arising from leases on the balance sheet and to provide additional disclosures about leasing arrangements.  ASU 2016-02 will be effective for reporting periods beginning after December 15, 2018, with early adoption permitted. The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.



Compensation-Stock Compensation



In March 2016, the FASB issued ASU 2016-09, “Compensation-Stock Compensation: Improvements to Employee Share Based Payment Accounting,” which includes multiple provisions intended to simplify various aspects of accounting for share-based payments.  The guidance is effective for reporting periods beginning after December 15, 2016, with early adoption permitted.  The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.





v3.4.0.3
Marketable Securities
3 Months Ended
Mar. 31, 2016
Marketable Securities [Abstract]  
Marketable Securities



3Marketable Securities



Marketable securities are considered “available-for-sale” in accordance with FASB Accounting Standard Codification (“ASC”) 320, “Debt and Equity Securities,” and thus are reported at fair value in the Company’s accompanying balance sheet, with unrealized gains and losses excluded from earnings and reported as a separate component of stockholders’ equity.  Amounts reclassified out of accumulated other comprehensive income (loss) into realized gains and losses are accounted for on the basis of specific identification and are included in other income or expense in the statement of operations.  The Company classifies such investments as current on the balance sheet as the investments are readily marketable and available for use in current operations. 



The following table shows the Company’s marketable securities’ adjusted cost, gross unrealized gains and losses, and fair value by significant investment category as of March 31, 2016 and December 31, 2015:





 

 

 

 

 

 

 

 

 



 

 

March 31, 2016



 

 

Cost

 

Gross
Unrealized

 

Gross
Unrealized

 

Fair



 

 

Basis

 

Gains

 

Losses

 

Value

Certificates of Deposit

 

$

6,000,000 

$

2,227 

$

(804)

$

6,001,423 

Commercial Paper

 

 

2,986,944 

 

 -

 

(2,124)

 

2,984,820 

Corporate Bonds

 

 

5,019,635 

 

138 

 

(843)

 

5,018,930 

Total Marketable Securities

 

$

14,006,579 

$

2,365 

$

(3,771)

$

14,005,173 



 

 

 

 

 

 

 

 

 



 

 

December 31, 2015



 

 

Cost

 

Gross
Unrealized

 

Gross
Unrealized

 

Fair



 

 

Basis

 

Gains

 

Losses

 

Value

Certificates of Deposit

 

$

6,240,000 

$

571 

$

(5,575)

$

6,234,996 

Commercial Paper

 

 

2,981,307 

 

 -

 

(3,737)

 

2,977,570 

Corporate Bonds

 

 

4,036,820 

 

 -

 

(9,300)

 

4,027,520 

Total Marketable Securities

 

$

13,258,127 

$

571 

$

(18,612)

$

13,240,086 



The Company typically invests in highly-rated securities, with the primary objective of minimizing the potential risk of principal loss.  As of March 31, 2016, the Company had 11 certificates of deposit with a fair value of $2,639,196 and unrealized losses of $804,  three commercial papers with an aggregate fair value of $2,984,820 and unrealized losses of $2,124, and three corporate bonds with an aggregate fair value of $3,014,440 and unrealized losses of $656, all of which have been unrealized losses for less than 12 months.  The Company has one corporate bond with a fair value of $1,001,890 and unrealized losses of $187 which has been an unrealized loss for greater than 12 months.  The Company does not intend to sell its marketable securities in an unrealized loss position.  Based upon these securities’ fair value relative to the cost, high ratings, and volatility of fair value, the Company considers the declines in market value of its marketable securities to be temporary in nature and does not consider any of its investments other-than-temporarily impaired, and anticipates that it will recover the entire amortized cost basis.



As of March 31 2016, all of the Company’s marketable securities are expected to mature in less than one year.

v3.4.0.3
Prepaid Expenses And Other Current Assets
3 Months Ended
Mar. 31, 2016
Prepaid Expenses and Other Current Assets [Abstract]  
Prepaid Expenses and Other Current Assets

4.  Prepaid Expenses and Other Current Assets





 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Deposits on contracts

 

$

316,743 

$

501,170 

Prepaid expenses and other current assets

 

 

629,318 

 

720,648 



 

 

 

 

 



 

$

946,061 

$

1,221,818 

 

Deposits on contracts consist of deposits on research and development contracts for services that had not been incurred as of the balance sheet date.  Prepaid expenses and other assets include prepaid general and administrative expenses, such as insurance, rent, investor relations fees and compensatory stock issued for services not yet incurred as of the balance sheet date. 

v3.4.0.3
Equipment, Net
3 Months Ended
Mar. 31, 2016
Equipment, Net [Abstract]  
Equipment, Net

5.  Equipment, Net





 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Furniture and fixtures

 

$

78,794 

$

78,794 

Office and computer equipment

 

 

109,862 

 

105,266 

Lab equipment

 

 

431,650 

 

431,650 

Leasehold improvements

 

 

133,762 

 

133,762 



 

 

 

 

 

Total equipment

 

 

754,068 

 

749,472 

Less: Accumulated depreciation and amortization

 

 

(642,733)

 

(636,572)



 

 

 

 

 

Net carrying amount

 

$

111,335 

$

112,900 

 

 

v3.4.0.3
Accounts Payable And Accrued Expenses
3 Months Ended
Mar. 31, 2016
Accounts Payable And Accrued Expenses [Abstract]  
Accounts Payable And Accrued Expenses

6.Accounts Payable and Accrued Expenses







 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Trade payables

 

$

1,132,858 

$

774,543 

Accrued expenses

 

 

125,725 

 

92,752 

Accrued research and development contract costs

 

 

1,884,445 

 

1,515,151 

Payroll liabilities

 

 

141,239 

 

278,852 



 

 

 

 

 



 

$

3,284,267 

$

2,661,298 



v3.4.0.3
Deferred Research And Development Arrangements
3 Months Ended
Mar. 31, 2016
Deferred Research And Development Arrangements [Abstract]  
Deferred Research And Development Arrangements

7.  Deferred Research and Development Arrangements

Rexgene Biotech Co., Ltd.

In 2003, the Company entered into a collaborative research agreement with Rexgene Biotech Co., Ltd. (“Rexgene”), a shareholder.  Rexgene is engaged in the development of pharmaceutical products in Asia and has agreed to assist the Company with the research, development and clinical trials necessary for registration of the Company’s drug candidate Archexin in Asia.  This agreement provides Rexgene with exclusive rights to license, sublicense, make, have made, use, sell and import Archexin in Asia.  In accordance with the agreement, Rexgene paid the Company a one-time fee of $1,500,000 in 2003.  The agreement terminates at the later of 20 years or the term of the patent.  The amortization reduces research and development expenses for the periods presented. 
 

The Company is using 20 years as its basis for recognition and accordingly research and development expenses were reduced by $18,750 for the three months ended March 31, 2016 and 2015.  The remaining $506,250 and $525,000 to be amortized at March 31, 2016 and December 31, 2015, respectively, is reflected as a deferred research and development arrangement on the balance sheet.  The payment from Rexgene is being used in the cooperative funding of the costs of development of Archexin. Royalties of 3% of net sales of licensed products will become payable by Rexgene to the Company on a quarterly basis once commercial sales of Archexin begin in Asia.  The product is still under development and commercial sales in Asia are not expected to begin until at least 2017.  Under the terms of the agreement, Rexgene does not receive royalties on the Company’s net sales outside of Asia.



v3.4.0.3
Other Liabilities
3 Months Ended
Mar. 31, 2016
Other Liabilities [Abstract]  
Other Liabilities

8. Other Liabilities



Deferred Lease Incentive



In accordance with the Company’s office lease agreement, as amended and further discussed in Note 14, the Company has been granted leasehold improvement allowances from the lessor to be used for the construction cost of improvements to the leased property, which included architectural and engineering fees, government agency plan check, permit and other fees, sales and use taxes, testing and inspection costs and telephone and data cabling and wiring in the premises.  The Company accounted for the benefit of the leasehold improvement allowance as a reduction of rental expense over the term of the office lease.

The following table sets forth the cumulative deferred lease incentive:





 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Deferred lease incentive

 

$

154,660 

$

154,660 

Less accumulated amortization

 

 

(114,219)

 

(111,108)



 

 

 

 

 

Balance

 

$

40,441 

$

43,552 

 

Deferred Office Lease Expense

 

The lease agreement, as amended, provided for an initial annual base rent with annual increases over the lease term.  The Company recognizes rental expense on a straight-line basis over the term of the lease, which resulted in a deferred rent liability of $57,867 and $60,468 as of March 31, 2016 and December 31, 2015, respectively.

 

v3.4.0.3
Net Loss Per Common Share
3 Months Ended
Mar. 31, 2016
Net Loss Per Common Share [Abstract]  
Net Loss Per Common Share

9.Net Loss per Common Share

Basic loss per common share is computed by dividing net loss by the weighted average number of shares of common stock outstanding for the period.  Diluted loss per common share is computed by dividing net loss by the weighted average number of shares of common stock outstanding, plus the number of common share equivalents that would be dilutive.  As of March 31, 2016 and December 31, 2015, there were stock options and warrants to acquire, in the aggregate, 54,919,976 and 39,082,886 shares of the Company’s common stock, respectively, that are potentially dilutive. However, diluted loss per share for all periods presented is the same as basic loss per share because the inclusion of common share equivalents would be anti-dilutive. 

v3.4.0.3
Common Stock
3 Months Ended
Mar. 31, 2016
Common Stock [Abstract]  
Common Stock

10.Common Stock

The following transactions occurred since December 31, 2015:

Public Offering

On March 2, 2016 the Company closed on a registered direct public offering to issue and sell 15,625,000 shares of common stock and warrants to purchase up to 11,718,750 shares of common stock.  The common stock and warrants were sold in units, consisting of common stock and a warrant to purchase 0.75 shares of common stock, at a price of $0.32 per unit, and the warrants have an exercise price of $0.42 per share.  The total gross proceeds of the offering were $5,000,000.  The warrants issued are exercisable beginning six months after the closing date until the five-year anniversary of the initial exercise date and were recorded as liabilities at fair value. 

A summary of the allocation of the proceeds of the offering is shown below:





 

 

 



 

 

 

Gross Proceeds:

 

$

5,000,000 



 

 

 

Allocated to warrant liabilities:

 

 

2,419,922 

Allocated to common stock and additional paid-in capital

 

 

2,580,078 



 

 

 

Total allocated gross proceeds:

 

$

5,000,000 





The closing costs of $575,751 included 781,250 warrants valued at $155,938 and $419,813 for placement agent and other fees.  Based upon the estimated fair value of the stock and warrants in the units, the Company allocated $169,887 to financing expense and $405,864 as stock issuance costs.



Compensatory Shares

During the three months ended March 31, 2016, the Company issued 135,000 shares to vendors in exchange for investor relations services.  The aggregate market value of the stock issued was $48,749.





v3.4.0.3
Stock-Based Compensation
3 Months Ended
Mar. 31, 2016
Stock-Based Compensation [Abstract]  
Stock-Based Compensation

11. Stock-Based Compensation

As of March 31, 2016, the Company had 15,928,072 options to purchase common stock outstanding.

At the Company’s Annual Meeting of the Stockholders held on June 10, 2013, the Company’s stockholders voted to approve the Rexahn Pharmaceuticals, Inc. 2013 Stock Option Plan (the “2013 Plan”).  Under the 2013 Plan, the Company grants stock options to key employees, directors and consultants of the Company.  A total of 17,000,000 shares of common stock have been reserved for issuance pursuant to the 2013 Plan.  As of March 31 2016, there were 10,129,572 options outstanding under the 2013 Plan, and 6,862,928 shares were available for issuance.

On August 5, 2003, the Company established a stock option plan (the “2003 Plan”).  Under the 2003 Plan, the Company granted stock options to key employees, directors and consultants of the Company.  With the adoption of the 2013 Plan, no new stock options may be issued under the 2003 Plan, but previously issued options under the 2003 Plan remain outstanding until their expiration.  As of March 31, 2016, there were 5,678,500 outstanding options under the 2003 Plan.    

In March 2016, the Company granted to a third party an option to purchase up to 120,000 shares of the Company’s common stock.  Of the Company’s outstanding options as of March 31, 2016, these were the only options that were not issued pursuant to the 2013 Plan or the 2003 Plan.

For the majority of the grants to employees, the vesting period is either (i) 30%,  30% and 40% on the first,  second and third anniversaries, of the grant date, respectively, or (ii) 25% each on the first four anniversaries.  With the exception of the options granted in March 2016, which have a three-year term, options expire between five and ten years from the date of grant. For the majority of grants to non-employee consultants of the Company, the vesting period is between one and three years, subject to the fulfillment of certain conditions in the individual stock agreements, or 100% upon the occurrence of certain events specified in the individual stock agreements.

Accounting for Awards

Stock option compensation expense is the estimated fair value of options granted amortized on a straight-line basis over the requisite vesting service period for the entire portion of the award. Total stock-based compensation recognized by the Company for the three months ended March 31, 2016 and 2015 is as follows:





 

 

 

 



 

 

 

 



 

 

 

 



For the Three Months Ended March 31,



2016

2015

Statement of operations line item:

 

 

 

 

General and administrative

$

215,327 

$

190,039 

Research and development

 

127,684 

 

82,347 



 

 

 

 

Total

$

343,011 

$

272,386 

No income tax benefit has been recognized in the statement of operations for stock-based compensation arrangements as the Company has provided for a 100% valuation allowance on its deferred tax assets.

Summary of Stock Option Transactions

There were 3,337,090 stock options granted at exercise prices ranging from $0.35 to $0.37 with an aggregate fair value of $732,042 during the three months ended March 31, 2016.  There were 3,426,316 stock options granted at exercise prices ranging from $0.71 to $0.89 with an aggregate fair value of $1,698,737 during the three months ended March 31, 2015. 

The fair value of options at the date of grant was estimated using the Black-Scholes option pricing model.  The Company took into consideration guidance under ASC 718, “Compensation-Stock Compensation” and Staff Accounting Bulletin No. 107 (“SAB 107”) when reviewing and updating assumptions.  The expected volatility is based upon historical volatility of the Company’s stock.  The expected term is based upon the simplified method as allowed under SAB 107.



The assumptions made in calculating the fair values of options are as follows:





 

 

 

 



 

 

 

 



Three Months Ended March 31,



2016

2015

Black-Scholes assumptions

 

 

 

 

Expected dividend yield

%

%

Expected volatility

32-75 

%

79-80 

%

Risk free interest rate

0.7-1.4

%

1.3-1.6

%

Expected term (in years)

2-6 years

 

6 years

 

   The following table summarizes share-based transactions:





 

 

 

 

 

 



 

 

 

 



Number of Options

 

Weighted Average Exercise Price

Weighted Average Remaining Contractual Term

 

Aggregate Intrinsic Value

Outstanding, January 1, 2016

12,590,982 

$

0.83 

6.8 years

$

26,500 

Granted

3,337,090 

 

0.35 

 

 

 

Exercised

 -

 

 -

 

 

 

Expired

 -

 

 -

 

 

 

Cancelled

 -

 

 -

 

 

 



 

 

 

 

 

 

Outstanding, March 31, 2016

15,928,072 

$

0.73 

7.2 years

$

10,600 

Exercisable, March 31, 2016

8,040,304 

$

0.88 

5.3 years

$

10,600 





The total intrinsic value of the options exercised was $98,051 for the three months ended March 31, 2015.  There were no stock options exercised during the three months ended March 31, 2016.  The weighted average fair value of the options granted was $0.22 and $0.49 for the three months ended March 31,  2016 and 2015 respectively.

A summary of the Company’s unvested options as of March 31, 2016 and changes during the three months ended March 31, 2016 is presented below:





 

 

 



 

 

 



2016



Number of  Options

Weighted Average Fair Value at Grant Date

Unvested at January 1, 2016

5,888,432 

$

0.51 

Granted

3,337,090 

$

0.22 

Vested

(1,337,754)

$

0.50 

Cancelled

 -

$

 -



 

 

 

Unvested at March 31, 2016

7,887,768 

$

0.39 

As of March 31, 2016 there was $2,618,945 of total unrecognized compensation cost related to unvested stock options, which is expected to be recognized over a weighted average vesting period of 2.6 years.

v3.4.0.3
Warrants
3 Months Ended
Mar. 31, 2016
Warrants [Abstract]  
Warrants

12. Warrants

As of March 31, 2016, warrants to purchase 38,991,904 shares were outstanding, having exercise prices ranging from $0.40 to $1.50 and expiration dates ranging from July 5, 2016 to September 2, 2021.  





 

 

 

 

 

 



 

 

 

 

 

 



2016

2015



Number of warrants

Weighted average exercise price

Number of warrants

Weighted average exercise price

Balance, January 1

26,491,904 

$

0.80  13,205,871 

$

1.07 

Issued during the period

12,500,000 

$

0.42 

 -

$

 -

Exercised during the period

 -

$

 -

 -

$

 -

Expired during the period

 -

$

 -

 -

$

 -



 

 

 

 

 

 

Balance, March 31

38,991,904 

$

0.68  13,205,871 

$

1.07 

At March 31, 2016 the weighted average remaining contractual life of the outstanding warrants was 4.1 years.  



The warrants issued to investors in the March 2011, December 2012, November 2015 and March 2016 offerings contain a provision for net cash settlement in the event that there is a fundamental transaction (contractually defined as a merger, sale of substantially all assets, tender offer or share exchange).  If a fundamental transaction occurs in which the consideration issued consists principally of cash or stock in a non-public company, then the warrant holder has the option to receive cash, equal to the fair value of the remaining unexercised portion of the warrant.  Due to this contingent redemption provision, the warrants require liability classification in accordance with ASC 480 and are recorded at fair value.  The warrants issued to investors in the July 2013, October 2013 and January 2014 offerings contain a fundamental transaction provision, but the warrant holders only have an option as to the type of consideration received if the holders of common stock receive an option as to their consideration.  In addition, the warrants issued in the March 2011, December 2012, July 2013, October 2013, January 2014, November 2015 and March 2016 contain a cashless exercise provision that is exercisable only in the event that a registration statement is not effective. That provision may not be operative if an effective registration statement is not available because an exemption under the U.S. securities laws may not be available to issue unregistered shares.  As a result, net cash settlement may be required, and the warrants require liability classification.



ASC 820 provides requirements for disclosure of liabilities that are measured at fair value on a recurring basis in periods subsequent to the initial recognition.  Fair values for warrants were determined using the Binomial Lattice (“Lattice”) valuation technique. The Lattice model provides for dynamic assumptions regarding volatility and risk-free interest rates within the total period to maturity. Accordingly, within the contractual term, the Company provided multiple date intervals over which multiple volatilities and risk free interest rates were used. These intervals allow the Lattice model to project outcomes along specific paths that consider volatilities and risk free rates that would be more likely in an early exercise scenario.



Significant assumptions are determined as follows:

Trading market values—Published trading market values;

Exercise price—Stated exercise price;

Term—Remaining contractual term of the warrant;

Volatility—Historical trading volatility for periods consistent with the remaining terms; and

Risk-free rate—Yields on zero coupon government securities with remaining terms consistent with the remaining terms of the warrants.



Due to the fundamental transaction provision, which could provide for early redemption of the warrants, the model also considered the probability the Company would enter into a fundamental transaction during the remaining term of the warrant. Because the Company is not yet achieving positive cash flow, management believes the probability of a fundamental transaction occurring over the term of the warrant is unlikely and therefore estimates the probability of entering into a fundamental transaction to be 5%.  For valuation purposes, the Company also assumed that if such a transaction did occur, it was more likely to occur towards the end of the term of the warrants.



The significant unobservable inputs used in the fair value measurement of the warrants include management’s estimate of the probability that a fundamental transaction may occur in the future.  Significant increases (decreases) in the probability of occurrence would result in a significantly higher (lower) fair value measurement.

The following table summarizes the fair value of the warrants as of the respective balance sheet dates:





 

 

 

 

 



 

 

 

 

 



 

Fair Value as of:

Warrant Issuance:

 

March 31, 2016

December 31, 2015

March 31, 2011 financing:

 

 

 

 

 

     Warrants to institutional investors

 

$

33 

$

30 

December 4, 2012 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

8,451 

 

9,818 

     Warrants to placement agent

 

 

529 

 

1,206 

July 26, 2013 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

90,766 

 

121,420 

     Warrants to placement agent

 

 

64 

 

384 

October 16, 2013 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

142,908 

 

169,349 

     Warrants to placement agent

 

 

145 

 

970 

January 21, 2014 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

106,190 

 

131,476 

November 12, 2015 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

1,840,663 

 

2,169,375 

     Warrants to placement agent

 

 

113,251 

 

135,135 

March 2, 2016 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

2,027,777 

 

 -

     Warrants to placement agent

 

 

128,291 

 

 -

Total:

 

$

4,459,068 

$

2,739,163 

The following table summarizes the number of shares indexed to the warrants as of the respective balance sheet dates:





 

 

 



 

 

 



 

Number of Shares indexed as of:

Warrant Issuance

 

March 31, 2016

December 31, 2015

March 31, 2011 financing:

 

 

 

     Warrants to institutional investors

 

3,333,333  3,333,333 

December 4, 2012 financing:

 

 

 

     Warrants to institutional investors

 

174,300  174,300 

     Warrants to placement agent

 

40,000  40,000 

July 26, 2013 financing:

 

 

 

     Warrants to institutional investors

 

2,000,000  2,000,000 

     Warrants to placement agent

 

124,032  124,032 

October 16, 2013 financing:

 

 

 

     Warrants to institutional investors

 

2,317,309  2,317,309 

     Warrants to placement agent

 

407,692  407,692 

January 21, 2014 financing:

 

 

 

     Warrants to institutional investors

 

4,761,905  4,761,905 

November 12, 2015 financing:

 

 

 

     Warrants to institutional investors

 

12,500,000  12,500,000 

     Warrants to placement agent

 

833,333  833,333 

March 2, 2016 financing:

 

 

 

     Warrants to institutional investors

 

11,718,750 

 -

     Warrants to placement agent

 

781,250 

 -

Total:

 

38,991,904  26,491,904 

The assumptions used in calculating the fair values of the warrants are as follows:





 

 

 

 

 

 

 



 

 

 

 

 

 

 



 

March 31, 2016

December 31, 2015

Trading market prices

 

$

0.33 

 

$

0.36 

 

Estimated future volatility

 

 

105 

%

 

105 

%

Dividend

 

 

-

 

 

-

 

Estimated future risk-free rate

 

 

0.23-1.70

%

 

0.82-2.38

%

Equivalent volatility

 

 

51-66 

%

 

44-65 

%

Equivalent risk-free rate

 

 

0.16-0.79

%

 

0.22-1.11

%



Changes in the fair value of the warrant liabilities, carried at fair value, as reported as “unrealized gain on fair value of warrants” in the statement of operations:









 

 

 

 



Three Months Ended March 31,



 

2016

 

2015

March 31, 2011 financing:

 

 

 

 

     Warrants to institutional investors

 

(3)

 

102,077 

December 4, 2012 financing:

 

 

 

 

     Warrants to institutional investors

 

1,368 

 

(2,897)

     Warrants to placement agent

 

677 

 

143 

July 26, 2013 financing:

 

 

 

 

     Warrants to institutional investors

 

30,654 

 

(24,786)

     Warrants to placement agent

 

321 

 

4,345 

October 16, 2013 financing:

 

 

 

 

     Warrants to institutional investors

 

26,440 

 

(17,760)

     Warrants to placement agent

 

826 

 

15,179 

January 21, 2014 financing:

 

 

 

 

     Warrants to institutional investors

 

25,286 

 

39,114 

November 12, 2015 financing:

 

 

 

 

     Warrants to institutional investors

 

328,713 

 

 -

     Warrants to placement agent

 

21,882 

 

 -

March 2, 2016 financing:

 

 

 

 

     Warrants to institutional investors

 

392,145 

 

 -

     Warrants to placement agent

 

27,646 

 

 -

Total:

$

855,955 

$

115,415 



v3.4.0.3
Income Taxes
3 Months Ended
Mar. 31, 2016
Income Taxes [Abstract]  
Income Taxes

13. Income Taxes

No provision for federal and state income taxes was required for the three months ended March 31,  2016 and 2015 due to the Company’s operating losses and increased deferred tax asset valuation allowance.  At March 31, 2016 and December 31, 2015, the Company had unused net operating loss carry-forwards of approximately $103,588,000 and $98,954,000, respectively, which expire at various dates through 2036.  Some of this amount may be subject to annual limitations under certain provisions of the Internal Revenue Code related to “changes in ownership.” 

As of March 31, 2016 and December 31, 2015, the deferred tax assets related to the aforementioned carry-forwards have been fully offset by valuation allowances, because significant utilization of such amounts is not presently expected in the foreseeable future. 

Deferred tax assets and valuation allowances consist of:





 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Net Operating Loss Carryforwards

 

$

40,399,000 

$

38,592,000 

Stock Compensation Expense

 

 

2,020,000 

 

1,891,000 

Book tax differences on assets and liabilities

 

 

324,000 

 

380,000 

Valuation Allowance

 

 

(42,743,000)

 

(40,863,000)



 

 

 

 

 

Net Deferred Tax Assets

 

$

 -

$

 -

 

The Company files income tax returns in the U.S. federal and Maryland state jurisdictions.  Tax years for fiscal 2012 through 2015 are open and potentially subject to examination by the federal and Maryland state taxing authorities.

v3.4.0.3
Commitments And Contingencies
3 Months Ended
Mar. 31, 2016
Commitments And Contingencies [Abstract]  
Commitments And Contingencies

14.Commitments and Contingencies

a)The Company has contracted with various vendors for research and development services, the  terms which require payments over the terms of the agreements, usually ranging from two to 36 months. The costs to be incurred are estimated and are subject to revision. As of March 31, 2016, the total estimated cost to complete these agreements was approximately $8,370,000.        All of these agreements may be terminated by either party upon appropriate notice as stipulated in the respective agreements.

b)On June 22, 2009, the Company entered into a License Agreement with Korea Research Institute of Chemical Technology (“KRICT”) to acquire the rights to all intellectual property related to quinoxaline-piperazine derivatives that were synthesized under a Joint Research Agreement.  The initial license fee was $100,000, all of which was paid as of December 31, 2009.  The agreement with KRICT calls for a one-time milestone payment of $1,000,000 within 30 days after the first achievement of marketing approval of the first commercial product arising out of or in connection with the use of KRICT’s intellectual properties.  As of March 31, 2016, the milestone has not occurred.

c)Office Space Lease

On June 7, 2013, the Company signed the first amendment to its commercial lease agreement for 5,466 square feet of office space in Rockville, Maryland.  The amendment extends the lease term until June 30, 2019.  Under the lease agreement, the Company pays its allocable portion of real estate taxes and common area operating charges.

On July 26, 2014 the Company entered into the second amendment to the lease agreement.  According to the terms of this amendment, the Company leased an additional 1,637 square feet of office space, beginning on September 1, 2014 and ending on August 31, 2015.  On May 6, 2015, the Company renewed the lease for this space for an additional year, beginning on September 1, 2015 and ending on August 31, 2016. 

Rent paid under the Company’s lease during the three months ended March 31, 2016 and 2015 was $51,301 and $50,058, respectively.

Prior Laboratory Lease

On August 26, 2014, the Company signed a one-year renewal to use laboratory space commencing on July 1, 2014 and ending on June 30, 2015.  The lease required monthly rental payments of $4,554.  Rent paid under the Company’s lease during the three months ended March 31, 2015 was $13,662. 

Current Laboratory Lease

On April 20, 2015, the Company signed a five-year lease agreement for 2,552 square feet of laboratory space commencing on July 1, 2015 and ending on June 30, 2020.  Under the lease agreement, the Company pays its allocable portion of real estate taxes and common area operating charges. Rent paid under this lease during the three months ended March 31, 2016 was $15,312.

Future rental payments over the next five years for all leases are as follows:



 

 

 



 

 

 

For the remaining nine months ending December 31:

2016

 

203,120 

For the year ending December 31:

2017

 

260,217 



2018

 

233,923 



2019

 

152,955 



2020

 

34,468 



 

 

 



Total

$

884,683 





d)The Company has established a 401(k) plan for its employees.  The Company has elected to match 100% of the first 3% of an employee’s compensation plus 50% of an additional 2% of the employee’s deferral. Expense related to this matching contribution aggregated to $31,503 and $29,359 for the three months ended March 31, 2016 and 2015, respectively.

e)In July 2013, the Company entered into an exclusive license agreement with the University of Maryland, Baltimore for a novel drug delivery platform, Nano-Polymer Drug Conjugate Systems.  RX-21101 is the Company’s first drug candidate utilizing this platform.  The agreement requires the Company to make payments to the University of Maryland if RX-21101 or any products from the licensed delivery platform achieve development milestones.  As of March 31, 2016, no development milestones have occurred.

f)  In October 2013, the Company signed an exclusive license agreement with the Ohio State Innovation Foundation, for a novel oligonucleotide drug delivery platform, Lipid-Coated Albumin Nanoparticle.  The agreement requires the Company to make payments to the Ohio State Innovation Foundation or any products from the licensed delivery platform achieve development milestones.  As of March 31, 2016, no development milestones have occurred.

v3.4.0.3
Fair Value Measurements
3 Months Ended
Mar. 31, 2016
Fair Value Measurements [Abstract]  
Fair Value Measurements

15.  Fair Value Measurements

ASC 820 defines fair value as the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date, not adjusted for transaction costs.  ASC 820 also establishes a fair value hierarchy that prioritizes the inputs to valuation techniques used to measure fair value into three broad levels giving the highest priority to quoted prices in active markets for identical assets or liabilities (Level 1) and the lowest priority to unobservable inputs (Level 3). 



The three levels are described below:



Level 1 Inputs

 

 

Unadjusted quoted prices in active markets for identical assets or liabilities that are accessible by the Company;

Level 2 Inputs

 

 

Quoted prices in markets that are not active or financial instruments for which all significant inputs are observable, either directly or indirectly; and

Level 3 Inputs

 

 

Unobservable inputs for the asset or liability including significant assumptions of the Company and other market participants.

The following tables present assets and liabilities that are measured at fair value on a recurring basis and are categorized using the fair value hierarchy.  There have been no changes in the methodologies used at March 31, 2016 and December 31, 2015. 

Dde



 

 

 

 

 

 

 

 



 

 

 

 

 

 

 

 

Fair Value Measurements at March 31, 2016



  Total  

Level 1

Level 2

Level 3

Assets:

 

 

 

 

 

 

 

 

     Certificates of Deposit

$

6,001,423 

$

 -

$

6,001,423 

$

 -

     Commercial Paper

 

2,984,820 

 

 -

 

2,984,820 

 

 -

     Corporate Bonds

 

5,018,930 

 

 -

 

5,018,930 

 

 -

Total Assets:

$

14,005,173 

$

 -

$

14,005,173 

$

 -



 

 

 

 

 

 

 

 

Liabilities: 

 

 

 

 

 

 

 

 

     Warrant Liabilities

$

4,459,068 

 

-

 

-

$

4,459,068 







 

 

 

 

 

 

 

 



Fair Value Measurements at December 31, 2015



  Total  

Level 1

Level 2

Level 3

Assets:

 

 

 

 

 

 

 

 

     Certificates of Deposit

$

6,234,996 

$

 -

$

6,234,996 

$

 -

     Commercial Paper

 

2,977,570 

 

 -

 

2,977,570 

 

 -

     Corporate Bonds

 

4,027,520 

 

 -

 

4,027,520 

 

 -

Total Assets:

$

13,240,086 

$

 -

$

13,240,086 

$

 -



 

 

 

 

 

 

 

 

Liabilities: 

 

 

 

 

 

 

 

 

     Warrant Liabilities

$

2,739,163 

 

-

 

-

$

2,739,163 



The fair value of the Company’s Level 2 marketable securities is determined by using quoted prices from independent pricing services that use market data for comparable securities in active or inactive markets.  A variety of data inputs, including benchmark yields, interest rates, known historical trades and broker dealer quotes are used with pricing models to determine the quoted prices.



The fair value methodology for the warrant liabilities is disclosed in Note 12.



The carrying amounts reported in the financial statements for cash and cash equivalents (Level 1), prepaid expenses, and other assets and accounts payable and accrued expenses approximate fair value because of the short term maturity of these financial instruments.



The following table sets forth a reconciliation of changes in the three months ended March 31, 2016 and 2015 in the fair value of the liabilities classified as Level 3 in the fair value hierarchy:







 

 

 



 

 

 



 

Warrant Liabilities

Balance at January 1, 2016

 

$

2,739,163 

Additions

 

 

2,575,860 

Unrealized gains, net

 

 

(855,955)

Transfers out of level 3

 

 

 -

Balance at March 31, 2016

 

$

4,459,068 

 





 

 

 



 

 

 



 

Warrant Liabilities

Balance at January 1, 2015

 

$

3,768,351 

Additions

 

 

 -

Unrealized gains, net

 

 

(115,415)

Transfers out of level 3

 

 

 -

Balance at March 31, 2015

 

$

3,652,936 

 

Additions consist of the fair value of warrant liabilities upon issuance.  Transfers out of Level 3 for warrant liabilities consist of warrant exercises, where the liability is converted to additional paid-in capital upon exercise.  The Company’s policy is to recognize transfers in and transfers out as of the actual date of the event or change in circumstance that caused the transfer.     

v3.4.0.3
Operations And Organization (Policies)
3 Months Ended
Mar. 31, 2016
Operations And Organization [Abstract]  
Operations

Operations

Rexahn Pharmaceuticals, Inc. (the “Company,”), a Delaware corporation, is a biopharmaceutical company whose principal operations are the discovery, development and commercialization of innovative treatments for cancer.  The Company had an accumulated deficit of $109,865,906 at March 31, 2016 and anticipates incurring losses through fiscal year 2016 and beyond.  The Company has not yet generated commercial revenues and has funded its operating losses to date through the sale of shares of its common stock and warrants to purchase shares of its common stock, convertible debt, financings, interest income from cash, cash equivalents and marketable securities, and proceeds from reimbursed research and development costs.  The Company believes that its cash, cash equivalents, and marketable securities, will be sufficient to cover its cash flow requirements for its current activities for at least the next 12 months.  Management believes it has the capability of managing the Company’s operations within existing cash available by focusing on select research and development activities, selecting projects in conjunction with potential financings and milestones, and efficiently managing its general and administrative affairs.

Basis Of Presentation

Basis of Presentation

The accompanying unaudited condensed financial statements of the Company have been prepared pursuant to the rules and regulations of the U.S. Securities and Exchange Commission for interim financial information.  Accordingly, they do not include all of the information and footnotes required by accounting principles generally accepted in the United States (“U.S. GAAP”) for complete financial statements.  In the opinion of the Company’s management, all adjustments (consisting of only normal recurring accruals) considered necessary for a fair presentation of the Company’s financial position as of March 31, 2016 and December 31, 2015 and of the results of operations, comprehensive loss and cash flows for the three months ended March 31, 2016 and 2015 have been included.  Operating results for the three months ended March 31, 2016 are not necessarily indicative of results that may be expected for any other interim period or the full fiscal year ending December 31, 2016. The accompanying unaudited condensed financial statements should be read in conjunction with the audited financial statements and notes thereto included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2015 (the “2015 Form 10-K”).  Information included in the condensed balance sheet as of December 31, 2015 has been derived from the Company’s audited financial statements for the year ended December 31, 2015 included in the 2015 Form 10-K.

Use of Estimates

Use of Estimates

The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period.  These estimates are based on management’s best knowledge of current events and actions the Company may undertake in the future.  Actual results may ultimately differ from these estimates.  These estimates are reviewed periodically, and as adjustments become necessary, they are reported in earnings in the period in which they become available.

v3.4.0.3
Recent Accounting Pronouncements Affecting The Company (Policies)
3 Months Ended
Mar. 31, 2016
Recent Accounting Pronouncements Affecting The Company [Abstract]  
Recent Accounting Pronouncements Affecting the Company

Revenue from Contracts with Customers



In May 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) 2014-09, “Revenue from Contracts with Customers,” a comprehensive new revenue recognition standard that will supersede nearly all existing revenue recognition guidance under U.S. GAAP. The standard’s core principle is that a company should recognize revenue when it transfers goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for those goods and services, and provides a revenue recognition framework in accordance with this principle.  On August 12, 2015, the FASB issued ASU 2015-14, which defers the effective date of ASU 2014-09 by one year to December 15, 2017 for annual reporting periods beginning after that date and interim periods therein.  Early adoption of the standard is permitted, but not before the original effective date of December 15, 2016.  The Company is currently evaluating the impact that the adoption of this guidance will have on its financial statements and future operating results.



Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern



In August 2014, the FASB issued ASU 2014-15, “Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern,” which requires management to perform interim and annual assessments as to the entity’s ability to continue as a going concern and provides related disclosure guidance.  ASU 2014-15 will be effective for reporting periods beginning after December 15, 2016, with early adoption permitted. The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.



Leases



In February 2016, the FASB issued ASU 2016-02, “Leases,” which requires an entity to recognize assets and liabilities arising from leases on the balance sheet and to provide additional disclosures about leasing arrangements.  ASU 2016-02 will be effective for reporting periods beginning after December 15, 2018, with early adoption permitted. The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.



Compensation-Stock Compensation



In March 2016, the FASB issued ASU 2016-09, “Compensation-Stock Compensation: Improvements to Employee Share Based Payment Accounting,” which includes multiple provisions intended to simplify various aspects of accounting for share-based payments.  The guidance is effective for reporting periods beginning after December 15, 2016, with early adoption permitted.  The Company is currently evaluating the impact the adoption of this guidance will have on its financial statements.

v3.4.0.3
Marketable Securities (Tables)
3 Months Ended
Mar. 31, 2016
Marketable Securities [Abstract]  
Schedule Of Cost And Fair Value Of Marketable Securities



 

 

 

 

 

 

 

 

 



 

 

March 31, 2016



 

 

Cost

 

Gross
Unrealized

 

Gross
Unrealized

 

Fair



 

 

Basis

 

Gains

 

Losses

 

Value

Certificates of Deposit

 

$

6,000,000 

$

2,227 

$

(804)

$

6,001,423 

Commercial Paper

 

 

2,986,944 

 

 -

 

(2,124)

 

2,984,820 

Corporate Bonds

 

 

5,019,635 

 

138 

 

(843)

 

5,018,930 

Total Marketable Securities

 

$

14,006,579 

$

2,365 

$

(3,771)

$

14,005,173 



 

 

 

 

 

 

 

 

 



 

 

December 31, 2015



 

 

Cost

 

Gross
Unrealized

 

Gross
Unrealized

 

Fair



 

 

Basis

 

Gains

 

Losses

 

Value

Certificates of Deposit

 

$

6,240,000 

$

571 

$

(5,575)

$

6,234,996 

Commercial Paper

 

 

2,981,307 

 

 -

 

(3,737)

 

2,977,570 

Corporate Bonds

 

 

4,036,820 

 

 -

 

(9,300)

 

4,027,520 

Total Marketable Securities

 

$

13,258,127 

$

571 

$

(18,612)

$

13,240,086 



v3.4.0.3
Prepaid Expenses And Other Current Assets (Tables)
3 Months Ended
Mar. 31, 2016
Prepaid Expenses and Other Current Assets [Abstract]  
Schedule Of Prepaid Expenses And Other Current Assets



 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Deposits on contracts

 

$

316,743 

$

501,170 

Prepaid expenses and other current assets

 

 

629,318 

 

720,648 



 

 

 

 

 



 

$

946,061 

$

1,221,818 



v3.4.0.3
Equipment, Net (Tables)
3 Months Ended
Mar. 31, 2016
Equipment, Net [Abstract]  
Schedule Of Equipment, Net



 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Furniture and fixtures

 

$

78,794 

$

78,794 

Office and computer equipment

 

 

109,862 

 

105,266 

Lab equipment

 

 

431,650 

 

431,650 

Leasehold improvements

 

 

133,762 

 

133,762 



 

 

 

 

 

Total equipment

 

 

754,068 

 

749,472 

Less: Accumulated depreciation and amortization

 

 

(642,733)

 

(636,572)



 

 

 

 

 

Net carrying amount

 

$

111,335 

$

112,900 



v3.4.0.3
Accounts Payable And Accrued Expenses (Tables)
3 Months Ended
Mar. 31, 2016
Accounts Payable And Accrued Expenses [Abstract]  
Schedule Of Accounts Payable And Accrued Expenses



 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Trade payables

 

$

1,132,858 

$

774,543 

Accrued expenses

 

 

125,725 

 

92,752 

Accrued research and development contract costs

 

 

1,884,445 

 

1,515,151 

Payroll liabilities

 

 

141,239 

 

278,852 



 

 

 

 

 



 

$

3,284,267 

$

2,661,298 



v3.4.0.3
Other Liabilities (Tables)
3 Months Ended
Mar. 31, 2016
Other Liabilities [Abstract]  
Schedule Of Deferred Lease Incentive



 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Deferred lease incentive

 

$

154,660 

$

154,660 

Less accumulated amortization

 

 

(114,219)

 

(111,108)



 

 

 

 

 

Balance

 

$

40,441 

$

43,552 



v3.4.0.3
Common Stock (Tables)
3 Months Ended
Mar. 31, 2016
Common Stock [Abstract]  
Summary Of Allocation Of Proceeds From Offering



 

 

 



 

 

 

Gross Proceeds:

 

$

5,000,000 



 

 

 

Allocated to warrant liabilities:

 

 

2,419,922 

Allocated to common stock and additional paid-in capital

 

 

2,580,078 



 

 

 

Total allocated gross proceeds:

 

$

5,000,000 



v3.4.0.3
Stock-Based Compensation (Tables)
3 Months Ended
Mar. 31, 2016
Stock-Based Compensation [Abstract]  
Summary Of Stock Compensation Expense



 

 

 

 



 

 

 

 



 

 

 

 



For the Three Months Ended March 31,



2016

2015

Statement of operations line item:

 

 

 

 

General and administrative

$

215,327 

$

190,039 

Research and development

 

127,684 

 

82,347 



 

 

 

 

Total

$

343,011 

$

272,386 



Schedule Of Assumptions Made In Calculating The Fair Value Of Options



 

 

 

 



 

 

 

 



Three Months Ended March 31,



2016

2015

Black-Scholes assumptions

 

 

 

 

Expected dividend yield

%

%

Expected volatility

32-75 

%

79-80 

%

Risk free interest rate

0.7-1.4

%

1.3-1.6

%

Expected term (in years)

2-6 years

 

6 years

 



Summary Of Employee And Non-Employee Transactions



 

 

 

 

 

 



 

 

 

 



Number of Options

 

Weighted Average Exercise Price

Weighted Average Remaining Contractual Term

 

Aggregate Intrinsic Value

Outstanding, January 1, 2016

12,590,982 

$

0.83 

6.8 years

$

26,500 

Granted

3,337,090 

 

0.35 

 

 

 

Exercised

 -

 

 -

 

 

 

Expired

 -

 

 -

 

 

 

Cancelled

 -

 

 -

 

 

 



 

 

 

 

 

 

Outstanding, March 31, 2016

15,928,072 

$

0.73 

7.2 years

$

10,600 

Exercisable, March 31, 2016

8,040,304 

$

0.88 

5.3 years

$

10,600 



Summary Of Unvested Shares



 

 

 



 

 

 



2016



Number of  Options

Weighted Average Fair Value at Grant Date

Unvested at January 1, 2016

5,888,432 

$

0.51 

Granted

3,337,090 

$

0.22 

Vested

(1,337,754)

$

0.50 

Cancelled

 -

$

 -



 

 

 

Unvested at March 31, 2016

7,887,768 

$

0.39 



v3.4.0.3
Warrants (Tables)
3 Months Ended
Mar. 31, 2016
Warrants [Abstract]  
Summary Of Changes In Warrants Outstanding During The Period



 

 

 

 

 

 



 

 

 

 

 

 



2016

2015



Number of warrants

Weighted average exercise price

Number of warrants

Weighted average exercise price

Balance, January 1

26,491,904 

$

0.80  13,205,871 

$

1.07 

Issued during the period

12,500,000 

$

0.42 

 -

$

 -

Exercised during the period

 -

$

 -

 -

$

 -

Expired during the period

 -

$

 -

 -

$

 -



 

 

 

 

 

 

Balance, March 31

38,991,904 

$

0.68  13,205,871 

$

1.07 



Schedule Of Fair Value Of Warrants Issued



 

 

 

 

 



 

 

 

 

 



 

Fair Value as of:

Warrant Issuance:

 

March 31, 2016

December 31, 2015

March 31, 2011 financing:

 

 

 

 

 

     Warrants to institutional investors

 

$

33 

$

30 

December 4, 2012 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

8,451 

 

9,818 

     Warrants to placement agent

 

 

529 

 

1,206 

July 26, 2013 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

90,766 

 

121,420 

     Warrants to placement agent

 

 

64 

 

384 

October 16, 2013 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

142,908 

 

169,349 

     Warrants to placement agent

 

 

145 

 

970 

January 21, 2014 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

106,190 

 

131,476 

November 12, 2015 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

1,840,663 

 

2,169,375 

     Warrants to placement agent

 

 

113,251 

 

135,135 

March 2, 2016 financing:

 

 

 

 

 

     Warrants to institutional investors

 

 

2,027,777 

 

 -

     Warrants to placement agent

 

 

128,291 

 

 -

Total:

 

$

4,459,068 

$

2,739,163 



Summary Of Shares Indexed To The Warrants



 

 

 



 

 

 



 

Number of Shares indexed as of:

Warrant Issuance

 

March 31, 2016

December 31, 2015

March 31, 2011 financing:

 

 

 

     Warrants to institutional investors

 

3,333,333  3,333,333 

December 4, 2012 financing:

 

 

 

     Warrants to institutional investors

 

174,300  174,300 

     Warrants to placement agent

 

40,000  40,000 

July 26, 2013 financing:

 

 

 

     Warrants to institutional investors

 

2,000,000  2,000,000 

     Warrants to placement agent

 

124,032  124,032 

October 16, 2013 financing:

 

 

 

     Warrants to institutional investors

 

2,317,309  2,317,309 

     Warrants to placement agent

 

407,692  407,692 

January 21, 2014 financing:

 

 

 

     Warrants to institutional investors

 

4,761,905  4,761,905 

November 12, 2015 financing:

 

 

 

     Warrants to institutional investors

 

12,500,000  12,500,000 

     Warrants to placement agent

 

833,333  833,333 

March 2, 2016 financing:

 

 

 

     Warrants to institutional investors

 

11,718,750 

 -

     Warrants to placement agent

 

781,250 

 -

Total:

 

38,991,904  26,491,904 



Schedule Of Assumptions Used In Calculating Fair Value Of Warrants



 

 

 

 

 

 

 



 

 

 

 

 

 

 



 

March 31, 2016

December 31, 2015

Trading market prices

 

$

0.33 

 

$

0.36 

 

Estimated future volatility

 

 

105 

%

 

105 

%

Dividend

 

 

-

 

 

-

 

Estimated future risk-free rate

 

 

0.23-1.70

%

 

0.82-2.38

%

Equivalent volatility

 

 

51-66 

%

 

44-65 

%

Equivalent risk-free rate

 

 

0.16-0.79

%

 

0.22-1.11

%



Schedule Of Unrealized Gain/(Loss) On Fair Value Of Warrants



 

 

 

 



Three Months Ended March 31,



 

2016

 

2015

March 31, 2011 financing:

 

 

 

 

     Warrants to institutional investors

 

(3)

 

102,077 

December 4, 2012 financing:

 

 

 

 

     Warrants to institutional investors

 

1,368 

 

(2,897)

     Warrants to placement agent

 

677 

 

143 

July 26, 2013 financing:

 

 

 

 

     Warrants to institutional investors

 

30,654 

 

(24,786)

     Warrants to placement agent

 

321 

 

4,345 

October 16, 2013 financing:

 

 

 

 

     Warrants to institutional investors

 

26,440 

 

(17,760)

     Warrants to placement agent

 

826 

 

15,179 

January 21, 2014 financing:

 

 

 

 

     Warrants to institutional investors

 

25,286 

 

39,114 

November 12, 2015 financing:

 

 

 

 

     Warrants to institutional investors

 

328,713 

 

 -

     Warrants to placement agent

 

21,882 

 

 -

March 2, 2016 financing:

 

 

 

 

     Warrants to institutional investors

 

392,145 

 

 -

     Warrants to placement agent

 

27,646 

 

 -

Total:

$

855,955 

$

115,415 



v3.4.0.3
Income Taxes (Tables)
3 Months Ended
Mar. 31, 2016
Income Taxes [Abstract]  
Schedule Of Deferred Tax Assets And Valuation Allowance



 

 

 

 

 



 

 

 

 

 



 

March 31,

December 31,



 

2016

2015



 

 

 

 

 

Net Operating Loss Carryforwards

 

$

40,399,000 

$

38,592,000 

Stock Compensation Expense

 

 

2,020,000 

 

1,891,000 

Book tax differences on assets and liabilities

 

 

324,000 

 

380,000 

Valuation Allowance

 

 

(42,743,000)

 

(40,863,000)



 

 

 

 

 

Net Deferred Tax Assets

 

$

 -

$

 -



v3.4.0.3
Commitments And Contingencies (Tables)
3 Months Ended
Mar. 31, 2016
Commitments And Contingencies [Abstract]  
Schedule Of Future Rental Payments



 

 

 



 

 

 

For the remaining nine months ending December 31:

2016

 

203,120 

For the year ending December 31:

2017

 

260,217 



2018

 

233,923 



2019

 

152,955 



2020

 

34,468 



 

 

 



Total

$

884,683 



v3.4.0.3
Fair Value Measurements (Tables)
3 Months Ended
Mar. 31, 2016
Fair Value Measurements [Abstract]  
Schedule Of Assets And Liabilities Measured At Fair Value On A Recurring Basis



 

 

 

 

 

 

 

 



 

 

 

 

 

 

 

 

Fair Value Measurements at March 31, 2016



  Total  

Level 1

Level 2

Level 3

Assets:

 

 

 

 

 

 

 

 

     Certificates of Deposit

$

6,001,423 

$

 -

$

6,001,423 

$

 -

     Commercial Paper

 

2,984,820 

 

 -

 

2,984,820 

 

 -

     Corporate Bonds

 

5,018,930 

 

 -

 

5,018,930 

 

 -

Total Assets:

$

14,005,173 

$

 -

$

14,005,173 

$

 -



 

 

 

 

 

 

 

 

Liabilities: 

 

 

 

 

 

 

 

 

     Warrant Liabilities

$

4,459,068 

 

-

 

-

$

4,459,068 







 

 

 

 

 

 

 

 



Fair Value Measurements at December 31, 2015



  Total  

Level 1

Level 2

Level 3

Assets:

 

 

 

 

 

 

 

 

     Certificates of Deposit

$

6,234,996 

$

 -

$

6,234,996 

$

 -

     Commercial Paper

 

2,977,570 

 

 -

 

2,977,570 

 

 -

     Corporate Bonds

 

4,027,520 

 

 -

 

4,027,520 

 

 -

Total Assets:

$

13,240,086 

$

 -

$

13,240,086 

$

 -



 

 

 

 

 

 

 

 

Liabilities: 

 

 

 

 

 

 

 

 

     Warrant Liabilities

$

2,739,163 

 

-

 

-

$

2,739,163 



Reconciliation Of Changes In The Fair Value Of Liabilities



 

 

 



 

 

 



 

Warrant Liabilities

Balance at January 1, 2016

 

$

2,739,163 

Additions

 

 

2,575,860 

Unrealized gains, net

 

 

(855,955)

Transfers out of level 3

 

 

 -

Balance at March 31, 2016

 

$

4,459,068 

 





 

 

 



 

 

 



 

Warrant Liabilities

Balance at January 1, 2015

 

$

3,768,351 

Additions

 

 

 -

Unrealized gains, net

 

 

(115,415)

Transfers out of level 3

 

 

 -

Balance at March 31, 2015

 

$

3,652,936 



v3.4.0.3
Operations And Organization (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Operations And Organization [Abstract]    
Accumulated deficit $ 109,865,906 $ 105,716,864
v3.4.0.3
Marketable Securities (Narrative) (Details)
Mar. 31, 2016
USD ($)
item
Dec. 31, 2015
USD ($)
Schedule of Available-for-sale Securities [Line Items]    
Fair value $ 14,005,173 $ 13,240,086
Unrealized losses $ 3,771 $ 18,612
11 Certificates Of Deposit With Unrealized Losses [Member]    
Schedule of Available-for-sale Securities [Line Items]    
Securities in a loss position, less than one year | item 11  
Fair value $ 2,639,196  
Unrealized losses $ 804  
3 Commercial Paper With Unrealized Losses [Member]    
Schedule of Available-for-sale Securities [Line Items]    
Securities in a loss position, less than one year | item 3  
Fair value $ 2,984,820  
Unrealized losses $ 2,124  
3 Corporate Bond Securities With Unrealized Losses [Member]    
Schedule of Available-for-sale Securities [Line Items]    
Securities in a loss position, less than one year | item 3  
Fair value $ 3,014,440  
Unrealized losses $ 656  
1 Corporate Bond Securities With Unrealized Losses [Member]    
Schedule of Available-for-sale Securities [Line Items]    
Securities in a loss position | item 1  
Fair value $ 1,001,890  
Unrealized losses $ 187  
v3.4.0.3
Marketable Securities (Schedule Of Cost And Fair Value Of Marketable Securities) (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Schedule of Available-for-sale Securities [Line Items]    
Cost Basis $ 14,006,579 $ 13,258,127
Gross Unrealized Gains 2,365 571
Gross Unrealized Losses (3,771) (18,612)
Fair value 14,005,173 13,240,086
Commercial Paper [Member]    
Schedule of Available-for-sale Securities [Line Items]    
Cost Basis 2,986,944 2,981,307
Gross Unrealized Losses (2,124) (3,737)
Fair value 2,984,820 2,977,570
Corporate Bonds [Member]    
Schedule of Available-for-sale Securities [Line Items]    
Cost Basis 5,019,635 4,036,820
Gross Unrealized Gains 138  
Gross Unrealized Losses (843) (9,300)
Fair value 5,018,930 4,027,520
Certificates of Deposit [Member]    
Schedule of Available-for-sale Securities [Line Items]    
Cost Basis 6,000,000 6,240,000
Gross Unrealized Gains 2,227 571
Gross Unrealized Losses (804) (5,575)
Fair value $ 6,001,423 $ 6,234,996
v3.4.0.3
Prepaid Expenses And Other Current Assets (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Prepaid Expenses and Other Current Assets [Abstract]    
Deposits on contracts $ 316,743 $ 501,170
Prepaid expenses and other current assets 629,318 720,648
Total prepaid expenses and other current assets $ 946,061 $ 1,221,818
v3.4.0.3
Equipment, Net (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Property, Plant and Equipment [Line Items]    
Total equipment $ 754,068 $ 749,472
Less: Accumulated depreciation and amortization (642,733) (636,572)
Net carrying amount 111,335 112,900
Furniture and Fixtures [Member]    
Property, Plant and Equipment [Line Items]    
Total equipment 78,794 78,794
Office and Computer Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Total equipment 109,862 105,266
Lab Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Total equipment 431,650 431,650
Leasehold Improvements [Member]    
Property, Plant and Equipment [Line Items]    
Total equipment $ 133,762 $ 133,762
v3.4.0.3
Accounts Payable And Accrued Expenses (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Accounts Payable And Accrued Expenses [Abstract]    
Trade payables $ 1,132,858 $ 774,543
Accrued expenses 125,725 92,752
Accrued research and development contract costs 1,884,445 1,515,151
Payroll liabilities 141,239 278,852
Total accounts payable and accrued expenses $ 3,284,267 $ 2,661,298
v3.4.0.3
Deferred Research And Development Arrangements (Details) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Dec. 31, 2003
Dec. 31, 2015
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Deferred Research and Development Arrangement $ 506,250     $ 525,000
Rexgene [Member]        
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Research and development arrangement, one-time fee     $ 1,500,000  
Reduction of research and development expenses $ 18,750 $ 18,750    
Research and development period 20 years      
Deferred Research and Development Arrangement $ 506,250     $ 525,000
Royalties paid, percentage of net sales 3.00%      
v3.4.0.3
Other Liabilities (Narrative) (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Other Liabilities [Abstract]    
Incentive from Lessor $ 154,660 $ 154,660
Accrued Rent $ 57,867 $ 60,468
v3.4.0.3
Other Liabilities (Schedule Of Deferred Lease Incentive) (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Other Liabilities [Abstract]    
Deferred lease incentive $ 154,660 $ 154,660
Less accumulated amortization (114,219) (111,108)
Balance $ 40,441 $ 43,552
v3.4.0.3
Net Loss Per Common Share (Details) - shares
3 Months Ended 12 Months Ended
Mar. 31, 2016
Dec. 31, 2015
Net Loss Per Common Share [Abstract]    
Potentially dilutive securities 54,919,976 39,082,886
v3.4.0.3
Common Stock (Narrative) (Details) - USD ($)
3 Months Ended
Mar. 02, 2016
Mar. 31, 2016
Mar. 31, 2015
Common Stock [Abstract]      
Shares issued 15,625,000    
Warrants issued 11,718,750 12,500,000
Share Price $ 0.32    
Proceeds from issuance $ 5,000,000    
Cash paid in exchange for closing costs 419,813    
Public offering closing costs 575,751    
Proceeds allocated to financing expense 169,887    
Issuance cost incurred $ 405,864    
Warrants issued per share of stock issued in unit offering 0.75    
Warrants issued included in closing costs 781,250    
Fair value of placement agent warrants $ 155,938    
Stock Warrants, Exercise Price $ 0.42    
Stock issued for services   135,000  
Aggregate market value stock issued for services   $ 48,749  
v3.4.0.3
Common Stock (Summary Of Allocation Of Proceeds From Offering) (Details)
Mar. 02, 2016
USD ($)
Common Stock [Abstract]  
Allocated to warrant liabilities $ 2,419,922
Allocated to Common stock and additional paid-in capital 2,580,078
Gross Proceeds: $ 5,000,000
v3.4.0.3
Stock-Based Compensation (Narrative) (Details) - USD ($)
1 Months Ended 3 Months Ended
Mar. 31, 2016
Mar. 31, 2016
Mar. 31, 2015
Dec. 31, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Percentage of Event Occurence to Vest   100.00%    
Number of options, Oustanding 15,928,072 15,928,072   12,590,982
Share-based compensation expense   $ 343,011 $ 272,386  
Income tax benefit from share-based compensation   $ 0    
Valuation allowance on deferred tax assets   100.00%    
Stock options granted   3,337,090    
Stock option exercise price   $ 0.35    
Intrinsic value of options exercised   $ 0 $ 98,051  
Weighted average fair value at grant date, Vested   $ 0.22 $ 0.49  
Unrecognized compensation cost $ 2,618,945 $ 2,618,945    
Weighted average vesting period, years   2 years 7 months 6 days    
March 2016 [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expiration of options from grant date, years   3 years    
The 2013 Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Options authorized for issuance 17,000,000 17,000,000    
Number of options, Oustanding 10,129,572 10,129,572    
Shares available for issuance 6,862,928 6,862,928    
The 2003 Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of options, Oustanding 5,678,500 5,678,500    
First Anniversary [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Vesting percentage   30.00%    
Second Anniversary [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Vesting percentage   30.00%    
Third Anniversary [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Vesting percentage   40.00%    
First Anniversary (B) [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Vesting percentage   25.00%    
Second Anniversary (B) [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Vesting percentage   25.00%    
Third Anniversary (B) [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Vesting percentage   25.00%    
Fourth Anniversary (B) [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Vesting percentage   25.00%    
Minimum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expiration of options from grant date, years   5 years    
Non-employee vesting period   1 year    
Maximum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expiration of options from grant date, years   10 years    
Non-employee vesting period   3 years    
Exercise Price Range $0.35 to $0.37 [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted   3,337,090    
Stock option grants fair value   $ 732,042    
Exercise Price Range $0.35 to $0.37 [Member] | Minimum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock option exercise price   $ 0.35    
Exercise Price Range $0.35 to $0.37 [Member] | Maximum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock option exercise price   $ 0.37    
Exercise Price Range $0.71 to $0.89 [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted     3,426,316  
Stock option grants fair value     $ 1,698,737  
Exercise Price Range $0.71 to $0.89 [Member] | Minimum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock option exercise price     $ 0.71  
Exercise Price Range $0.71 to $0.89 [Member] | Maximum [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock option exercise price     $ 0.89  
Third Party [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Stock options granted 120,000      
v3.4.0.3
Stock-Based Compensation (Summary Of Stock Compensation Expense) (Details) - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share Based Compensation $ 343,011 $ 272,386
General and administrative [Member]    
Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share Based Compensation 215,327 190,039
Research and development [Member]    
Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Share Based Compensation $ 127,684 $ 82,347
v3.4.0.3
Stock-Based Compensation (Schedule Of Assumptions Made In Calculating The Fair Value Of Options) (Details)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Expected dividend yield 0.00% 0.00%
Expected volatility, minimum 32.00% 79.00%
Expected volatility, maximum 75.00% 80.00%
Risk free interest rate, minimum 0.70% 1.30%
Risk free interest rate, maximum 1.40% 1.60%
Expected term (in years)   6 years
Minimum [Member]    
Expected term (in years) 2 years  
Maximum [Member]    
Expected term (in years) 6 years  
v3.4.0.3
Stock-Based Compensation (Summary Of Employee And Non-Employee Transactions) (Details)
3 Months Ended 12 Months Ended
Mar. 31, 2016
USD ($)
$ / shares
shares
Dec. 31, 2015
USD ($)
$ / shares
shares
Stock-Based Compensation [Abstract]    
Number of options, Oustanding | shares 12,590,982  
Number of options, Granted | shares 3,337,090  
Number of options, Oustanding | shares 15,928,072 12,590,982
Weighted average exercise price, Outstanding | $ / shares $ 0.83  
Weighted average exercise price, Granted | $ / shares 0.35  
Weighted average exercise price, Outstanding | $ / shares $ 0.73 $ 0.83
Weighted average remaining contractual term, Outstanding 7 years 2 months 12 days 6 years 9 months 18 days
Aggregate intrinsic value, Outstanding | $ $ 10,600 $ 26,500
Number of options, Exercisable | shares 8,040,304  
Weighted average exercise price, Exercisable | $ / shares $ 0.88  
Weighted average remaining contractual term, Exercisable 5 years 3 months 18 days  
Aggregate intrinsic value, Exercisable | $ $ 10,600  
v3.4.0.3
Stock-Based Compensation (Summary Of Unvested Shares) (Details) - $ / shares
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items]    
Weighted average fair value at grant date, Vested $ 0.22 $ 0.49
Nonvested Options [Member]    
Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items]    
Number of options, outstanding 5,888,432  
Number of options, Granted 3,337,090  
Number of options, Vested (1,337,754)  
Number of options, Cancelled  
Number of options, outstanding 7,887,768  
Weighted average fair value at grant date, Unvested $ 0.51  
Weighted average fair value at grant date, Granted 0.22  
Weighted average fair value at grant date, Vested $ 0.50  
Weighted average fair value at grant date, Cancelled  
Weighted average fair value at grant date, Unvested $ 0.39  
v3.4.0.3
Warrants (Narrative) (Details) - $ / shares
3 Months Ended
Mar. 31, 2016
Dec. 31, 2015
Mar. 31, 2015
Dec. 31, 2014
Class of Warrant or Right [Line Items]        
Number of warrants, Outstanding 38,991,904 26,491,904 13,205,871 13,205,871
Exercise price $ 0.68 $ 0.80 $ 1.07 $ 1.07
Warrant expiration date, start Jul. 05, 2016      
Warrant expiration date, end Sep. 02, 2021      
Average remaining contractual life of warrants outstanding 4 years 1 month 6 days      
Probability of entering into a fundamental transaction 5.00%      
Maximum [Member]        
Class of Warrant or Right [Line Items]        
Exercise price $ 1.50      
Minimum [Member]        
Class of Warrant or Right [Line Items]        
Exercise price $ 0.40      
v3.4.0.3
Warrants (Summary Of Changes In Warrants Outstanding During The Period) (Details) - $ / shares
3 Months Ended
Mar. 02, 2016
Mar. 31, 2016
Mar. 31, 2015
Warrants [Abstract]      
Number of warrants, Outstanding   26,491,904 13,205,871
Weigted average exercise price, Outstanding   $ 0.80 $ 1.07
Number of warrants, Issued 11,718,750 12,500,000
Weighted average exercise price, Issued   $ 0.42
Number of warrants, Exercised    
Weighted average exercise price, Exercised    
Number of warrants, Expired    
Weighted average exercise price, Expired    
Number of warrants, Outstanding   38,991,904 13,205,871
Weigted average exercise price, Outstanding   $ 0.68 $ 1.07
v3.4.0.3
Warrants (Schedule Of Fair Value Of Warrants Issued) (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Class of Warrant or Right [Line Items]    
Fair value $ 4,459,068 $ 2,739,163
March 31, 2011 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Fair value 33 30
December 4, 2012 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Fair value 8,451 9,818
December 4, 2012 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Fair value 529 1,206
July 26, 2013 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Fair value 90,766 121,420
July 26, 2013 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Fair value 64 384
October 16, 2013 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Fair value 142,908 169,349
October 16, 2013 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Fair value 145 970
January 21, 2014 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Fair value 106,190 131,476
November 12, 2015 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Fair value 1,840,663 2,169,375
November 12, 2015 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Fair value 113,251 $ 135,135
March 2, 2016 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Fair value 2,027,777  
March 2, 2016 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Fair value $ 128,291  
v3.4.0.3
Warrants (Summary Of Shares Indexed To The Warrants) (Details) - shares
Mar. 31, 2016
Dec. 31, 2015
Class of Warrant or Right [Line Items]    
Number of shares indexed 38,991,904 26,491,904
March 31, 2011 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 3,333,333 3,333,333
December 4, 2012 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 174,300 174,300
December 4, 2012 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 40,000 40,000
July 26, 2013 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 2,000,000 2,000,000
July 26, 2013 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 124,032 124,032
October 16, 2013 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 2,317,309 2,317,309
October 16, 2013 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 407,692 407,692
January 21, 2014 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 4,761,905 4,761,905
November 12, 2015 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 12,500,000 12,500,000
November 12, 2015 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 833,333 833,333
March 2, 2016 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 11,718,750  
March 2, 2016 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Number of shares indexed 781,250  
v3.4.0.3
Warrants (Schedule Of Assumptions Used In Calculating Fair Value Of Warrants) (Details) - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2016
Dec. 31, 2015
Warrants [Abstract]    
Trading market prices $ 0.33 $ 0.36
Estimated future volatility 105.00% 105.00%
Dividend
Estimated future risk-free rate, minimum 0.23% 0.82%
Estimated future risk-free rate, maximum 1.70% 2.38%
Equivalent volatility, minimum 51.00% 44.00%
Equivalent volatility, maximum 66.00% 65.00%
Equivalent risk-free rate, minimum 0.16% 0.22%
Equivalent risk-free rate, maximum 0.79% 1.11%
v3.4.0.3
Warrants (Schedule Of Unrealized Gain/(Loss) On Fair Value Of Warrants) (Details) - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants $ 855,955 $ 115,415
March 31, 2011 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants (3) 102,077
December 4, 2012 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 1,368 (2,897)
December 4, 2012 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 677 143
July 26, 2013 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 30,654 (24,786)
July 26, 2013 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 321 4,345
October 16, 2013 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 26,440 (17,760)
October 16, 2013 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 826 15,179
January 21, 2014 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 25,286 $ 39,114
November 12, 2015 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 328,713  
November 12, 2015 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 21,882  
March 2, 2016 Warrants To Institutional Investors [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants 392,145  
March 2, 2016 Warrants To Placement Agent [Member]    
Class of Warrant or Right [Line Items]    
Unrealized gain on fair value of warrants $ 27,646  
v3.4.0.3
Income Taxes (Narrative) (Details) - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Dec. 31, 2015
Operating Loss Carryforwards [Line Items]      
Provision for income taxes  
Operating loss carry-forward $ 103,588,000   $ 98,954,000
Net operating loss carry-forwards expiration Dec. 31, 2036    
Federal And State [Member]      
Operating Loss Carryforwards [Line Items]      
Provision for income taxes $ 0 $ 0  
v3.4.0.3
Income Taxes (Schedule Of Deferred Tax Assets And Valuation Allowance) (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Income Taxes [Abstract]    
Net Operating Loss Carryforwards $ 40,399,000 $ 38,592,000
Stock Compensation Expense 2,020,000 1,891,000
Book tax differences on assets and liabilities 324,000 380,000
Valuation Allowance $ (42,743,000) $ (40,863,000)
Net Deferred Tax Assets
v3.4.0.3
Commitments And Contingencies (Narrative) (Details)
3 Months Ended 12 Months Ended
Apr. 20, 2015
ft²
Jul. 26, 2014
ft²
Jun. 07, 2013
ft²
Jun. 22, 2009
USD ($)
Mar. 31, 2016
USD ($)
Mar. 31, 2015
USD ($)
Dec. 31, 2009
USD ($)
Commitments And Contingencies [Line Items]              
Estimated cost to complete contracts         $ 8,370,000    
Size of lease space | ft²     5,466        
Additional office space | ft²   1,637          
License Costs             $ 100,000
One-time milestone payment       $ 1,000,000      
Employer matching contribution         100.00%    
Maximum percentage of employee's gross pay         3.00%    
Employer matching contribution on deferral         50.00%    
Percentage of employee's gross pay         2.00%    
Expense related to matching contribution         $ 31,503 $ 29,359  
Maximum [Member]              
Commitments And Contingencies [Line Items]              
Contract term, months         36 months    
Minimum [Member]              
Commitments And Contingencies [Line Items]              
Contract term, months         2 months    
Prior Laboratory Lease [Member]              
Commitments And Contingencies [Line Items]              
Lease term         1 year    
Required monthly rental payments         $ 4,554    
Rent expense           13,662  
Current Laboratory Lease [Member]              
Commitments And Contingencies [Line Items]              
Lease term         5 years    
Size of lease space | ft² 2,552            
Rent expense         $ 15,312    
Office Space Rental [Member]              
Commitments And Contingencies [Line Items]              
Rent expense         $ 51,301 $ 50,058  
v3.4.0.3
Commitments and Contingencies (Schedule of Future Rental Payments) (Details)
Mar. 31, 2016
USD ($)
Commitments And Contingencies [Abstract]  
2016 $ 203,120
2017 260,217
2018 233,923
2019 152,955
2020 34,468
Total $ 884,683
v3.4.0.3
Fair Value Measurements (Schedule Of Assets And Liabilities Measured At Fair Value On A Recurring Basis) (Details) - USD ($)
Mar. 31, 2016
Dec. 31, 2015
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Total Assets: $ 14,005,173 $ 13,240,086
Warrant Liabilities 4,459,068 2,739,163
Corporate Bonds [Member]    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Total Assets: 5,018,930 4,027,520
Certificates of Deposit [Member]    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Total Assets: 6,001,423 6,234,996
Commercial Paper [Member]    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Total Assets: 2,984,820 2,977,570
Level 2 [Member]    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Total Assets: 14,005,173 13,240,086
Level 2 [Member] | Corporate Bonds [Member]    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Total Assets: 5,018,930 4,027,520
Level 2 [Member] | Certificates of Deposit [Member]    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Total Assets: 6,001,423 6,234,996
Level 2 [Member] | Commercial Paper [Member]    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Total Assets: 2,984,820 2,977,570
Level 3 [Member]    
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]    
Warrant Liabilities $ 4,459,068 $ 2,739,163
v3.4.0.3
Fair Value Measurements (Reconciliation Of Changes In The Fair Value Of Liabilities) (Details) - Warrant Liabilities [Member] - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]    
Balance $ 2,739,163 $ 3,768,351
Additions 2,575,860  
Unrealized gains, net (855,955) (115,415)
Balance $ 4,459,068 $ 3,652,936
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/**
 * Rivet Software Inc.
 *
 * @copyright Copyright (c) 2006-2011 Rivet Software, Inc. All rights reserved.
 * Version 2.4.0.3
 *
 */

var Show = {};
Show.LastAR = null,

Show.hideAR = function(){	
	Show.LastAR.style.display = 'none';
};

Show.showAR = function ( link, id, win ){
	if( Show.LastAR ){
		Show.hideAR();
	}
		
	var ref = link;
	do {
		ref = ref.nextSibling;
	} while (ref && ref.nodeName != 'TABLE');

	if (!ref || ref.nodeName != 'TABLE') {
		var tmp = win ?
			win.document.getElementById(id) :
			document.getElementById(id);

		if( tmp ){
			ref = tmp.cloneNode(true);
			ref.id = '';
			link.parentNode.appendChild(ref);
		}
	}

	if( ref ){
		ref.style.display = 'block';
		Show.LastAR = ref;
	}
};
	
Show.toggleNext = function( link ){
	var ref = link;
	
	do{
		ref = ref.nextSibling;	
	}while( ref.nodeName != 'DIV' );

	if( ref.style &&
		ref.style.display &&
		ref.style.display == 'none' ){
		ref.style.display = 'block';

		if( link.textContent ){
			link.textContent = link.textContent.replace( '+', '-' );
		}else{
			link.innerText = link.innerText.replace( '+', '-' );
		}
	}else{
		ref.style.display = 'none';
			
		if( link.textContent ){
			link.textContent = link.textContent.replace( '-', '+' );
		}else{
			link.innerText = link.innerText.replace( '-', '+' );
		}
	}
};

/* Updated 2009-11-04 */
/* v2.2.0.24 */

/* DefRef Styles */
.report table.authRefData{
	background-color: #def;
	border: 2px solid #2F4497;
	font-size: 1em; 
	position: absolute;
}

.report table.authRefData a {
	display: block;
	font-weight: bold;
}

.report table.authRefData p {
	margin-top: 0px;
}

.report table.authRefData .hide {
	background-color: #2F4497;
	padding: 1px 3px 0px 0px;
	text-align: right;
}

.report table.authRefData .hide a:hover {
	background-color: #2F4497;
}

.report table.authRefData .body {
	height: 150px;
	overflow: auto;
	width: 400px;
}

.report table.authRefData table{
	font-size: 1em;
}

/* Report Styles */
.pl a, .pl a:visited {
	color: black;
	text-decoration: none;
}

/* table */
.report {
	background-color: white;
	border: 2px solid #acf;
	clear: both;
	color: black;
	font: normal 8pt Helvetica, Arial, san-serif;
	margin-bottom: 2em;
}

.report hr {
	border: 1px solid #acf;
}

/* Top labels */
.report th {
	background-color: #acf;
	color: black;
	font-weight: bold;
	text-align: center;
}

.report th.void	{
	background-color: transparent;
	color: #000000;
	font: bold 10pt Helvetica, Arial, san-serif;
	text-align: left;
}

.report .pl {
	text-align: left;
	vertical-align: top;
	white-space: normal;
	width: 200px;
	white-space: normal; /* word-wrap: break-word; */
}

.report td.pl a.a {
	cursor: pointer;
	display: block;
	width: 200px;
	overflow: hidden;
}

.report td.pl div.a {
	width: 200px;
}

.report td.pl a:hover {
	background-color: #ffc;
}

/* Header rows... */
.report tr.rh {
	background-color: #acf;
	color: black;
	font-weight: bold;
}

/* Calendars... */
.report .rc {
	background-color: #f0f0f0;
}

/* Even rows... */
.report .re, .report .reu {
	background-color: #def;
}

.report .reu td {
	border-bottom: 1px solid black;
}

/* Odd rows... */
.report .ro, .report .rou {
	background-color: white;
}

.report .rou td {
	border-bottom: 1px solid black;
}

.report .rou table td, .report .reu table td {
	border-bottom: 0px solid black;
}

/* styles for footnote marker */
.report .fn {
	white-space: nowrap;
}

/* styles for numeric types */
.report .num, .report .nump {
	text-align: right;
	white-space: nowrap;
}

.report .nump {
	padding-left: 2em;
}

.report .nump {
	padding: 0px 0.4em 0px 2em;
}

/* styles for text types */
.report .text {
	text-align: left;
	white-space: normal;
}

.report .text .big {
	margin-bottom: 1em;
	width: 17em;
}

.report .text .more {
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