Form IRANNOTICE Banco Santander, S.A.

| 27 February 2026 | |||||
Securities and Exchange Commission
100 F Street N.E.
Washington, DC 20549
100 F Street N.E.
Washington, DC 20549
| Re: | Annual Report on Form 20-F for the Year Ended 31 December 2025; | ||||
| Notice of disclosure under Section 13(r) of the Securities Exchange Act of 1934 | |||||
Ladies and Gentlemen:
We give notice to the Commission that we have provided disclosure under Section 13(r) of the Securities Exchange Act of 1934 in our Annual Report on Form 20-F for the year ended 31 December 2025.
Very truly yours,
Banco Santander S.A.
| By: | /s/ David Hazell | |||||||
| David Hazell | ||||||||
| Chief Compliance Officer | ||||||||
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