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Form 13F-HR DEERFIELD MANAGEMENT For: Dec 31

February 16, 2021 4:38 PM EST

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE

OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8

Report for the Calendar Year or Quarter Ended: 12-31-2020
Check here if Amendment   Amendment Number:
This Amendment (Check only one.):   is a restatement.
  adds new holdings entries.
Institutional Investment Manager Filing this Report:
Name: DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)
Address: 345 Park Avenue South, 12th Floor
New York , NY10010
Form 13F File Number: 028-05366

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report on Behalf of Reporting Manager:
Name: James E. Flynn
Title: Managing Member
Phone: 2125511600
Signature, Place, and Date of Signing:
/s/ James E. Flynn New York , NY 02-12-2021
[Signature] [City, State] [Date]
Report Type (Check only one.):
X 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.)
  13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).)
  13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)
Form 13F Summary Page
Report Summary:
Number of Other Included Managers: 1
Form 13F Information Table Entry Total: 129
Form 13F Information Table Value Total: 5,059,781
(thousands)
List of Other Managers Reporting for this Manager:
[If there are no entries in this list, omit this section.]
Form 13F File Number Name
028-11827 Flynn Management LLC

List of Other Included Managers:
Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]
No. Form 13F File Number Name
1 028-11827 Flynn Management LLC

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100 6,218 150,000 SH DFND 1 150,000 0 0
908 DEVICES INC COM 65443P102 4,271 75,000 SH DFND 1 75,000 0 0
ACCELERON PHARMA INC COM 00434H108 53,942 421,619 SH DFND 1 421,619 0 0
ACCOLADE INC COM 00437E102 27,753 638,001 SH DFND 1 638,001 0 0
ACUTUS MED INC COM 005111109 125,087 4,341,799 SH DFND 1 4,341,799 0 0
ADAPTHEALTH CORP COM CL A 00653Q102 67,846 1,806,332 SH DFND 1 1,806,332 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 26,064 2,404,439 SH DFND 1 2,404,439 0 0
AERIE PHARMACEUTICALS INC NOTE 1.500%10/0 00771VAB4 137,072 149,600,000 SH DFND 1 149,600,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 15,699 1,162,033 SH DFND 1 1,162,033 0 0
ALECTOR INC COM 014442107 15,965 1,055,192 SH DFND 1 1,055,192 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 90,502 579,248 PRN DFND 1 579,248 0 0
ALIGOS THERAPEUTICS INC COM 01626L105 16,590 600,000 SH DFND 1 600,000 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 29,040 2,000,000 SH DFND 1 2,000,000 0 0
AMERICAN WELL CORP CL A 03044L105 20,039 791,115 SH DFND 1 791,115 0 0
ANNEXON INC COM 03589W102 29,231 1,167,826 SH DFND 1 1,167,826 0 0
APELLIS PHARMACEUTICALS INC NOTE 3.500% 9/1 03753UAB2 92,483 54,825,000 SH DFND 1 54,825,000 0 0
ARDELYX INC COM 039697107 16,573 2,561,554 SH DFND 1 2,561,554 0 0
ARVINAS INC COM 04335A105 6,370 75,000 SH DFND 1 75,000 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 11,585 453,973 SH DFND 1 453,973 0 0
AVROBIO INC COM 05455M100 11,152 800,000 SH DFND 1 800,000 0 0
AXONICS MODULATION TECHNOLOG COM 05465P101 39,936 800,000 SH DFND 1 800,000 0 0
BENEFITFOCUS INC NOTE 1.250%12/1 08180DAB2 5,713 6,500,000 SH DFND 1 6,500,000 0 0
BIOATLA INC COM 09077B104 9,537 280,422 SH DFND 1 280,422 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 43,477 5,835,810 SH DFND 1 5,835,810 0 0
BIODELIVERY SCIENCES INTL IN COM 09060J106 40,026 9,530,000 SH DFND 1 9,530,000 0 0
BIOGEN INC COM 09062X103 109,697 448,000 SH DFND 1 448,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 14,293 163,000 SH DFND 1 163,000 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 25,720 802,511 SH DFND 1 802,511 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 45,464 405,386 PRN DFND 1 405,386 0 0
BOSTON SCIENTIFIC CORP COM 101137107 14,632 407,000 PRN DFND 1 407,000 0 0
BROOKDALE SR LIVING INC COM 112463104 48,834 11,023,465 SH DFND 1 11,023,465 0 0
CABALETTA BIO INC COM 12674W109 5,794 464,252 SH DFND 1 464,252 0 0
CENTENE CORP DEL COM 15135B101 145,873 2,430,000 SH DFND 1 2,430,000 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 6,384 385,043 SH DFND 1 385,043 0 0
CEREVEL THERAPEUTICS HLDNG I *W EXP 06/09/202 15678U102 942 166,666 SH DFND 1 166,666 0 0
CERTARA INC COM 15687V109 20,232 600,000 SH DFND 1 600,000 0 0
CLOVIS ONCOLOGY INC NOTE 2.500% 9/1 189464AB6 45,236 49,064,000 SH DFND 1 49,064,000 0 0
CODIAK BIOSCIENCES INC COM 192010106 14,535 450,000 SH DFND 1 450,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 11,230 1,000,000 SH DFND 1 1,000,000 0 0
CONSONANCE HFW ACQUISITION C UNIT 99/99/9999 G2445M129 5,235 500,000 SH DFND 1 500,000 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 42,018 1,458,957 SH DFND 1 1,458,957 0 0
CYTOKINETICS INC COM NEW 23282W605 51,140 2,461,000 SH DFND 1 2,461,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 30,166 528,585 SH DFND 1 528,585 0 0
DEERFIELD HEALTHCARE TECH AC UNIT 07/16/2025 244413209 50,400 3,360,000 SH DFND 1 3,360,000 0 0
DEERFIELD HEALTHCARE TECH AC COM CL A 244413100 53,333 3,418,750 SH DFND 1 3,418,750 0 0
DELCATH SYS INC COM NEW 24661P807 8,960 500,000 SH DFND 1 500,000 0 0
DFP HEALTHCARE ACQUISITNS CO UNIT 03/31/2025 23343Q209 56,051 5,000,000 SH DFND 1 5,000,000 0 0
DFP HEALTHCARE ACQUISITNS CO COM CL A 23343Q100 58,968 5,460,000 SH DFND 1 5,460,000 0 0
DYNE THERAPEUTICS INC COM 26818M108 11,970 570,000 SH DFND 1 570,000 0 0
EARGO INC COM 270087109 5,603 125,000 SH DFND 1 125,000 0 0
EDITAS MEDICINE INC COM 28106W103 37,770 538,721 SH DFND 1 538,721 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114 10,660 1,000,000 SH DFND 1 1,000,000 0 0
FATE THERAPEUTICS INC COM 31189P102 51,291 564,067 PRN DFND 1 564,067 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 1,908 162,378 SH DFND 1 162,378 0 0
GENERATION BIO CO COM 37148K100 27,250 961,215 SH DFND 1 961,215 0 0
GRAYBUG VISION INC COM SHS 38942Q103 153,275 5,281,713 SH DFND 1 5,281,713 0 0
HIGHCAPE CAP ACQUISITION COR UNIT 09/30/2027 42984L204 10,320 1,000,000 SH DFND 1 1,000,000 0 0
IMARA INC COM 45249V107 12,742 577,868 SH DFND 1 577,868 0 0
INOZYME PHARMA INC COM 45790W108 23,742 1,150,299 SH DFND 1 1,150,299 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 69,219 61,000,000 SH DFND 1 61,000,000 0 0
INSULET CORP NOTE 0.375% 9/0 45784PAK7 76,424 57,581,000 SH DFND 1 57,581,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.250% 7/0 45845PAA6 45,738 57,791,000 SH DFND 1 57,791,000 0 0
INTERSECT ENT INC COM 46071F103 5,850 255,456 SH DFND 1 255,456 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 15,765 793,803 SH DFND 1 793,803 0 0
IVERIC BIO INC COM 46583P102 39,853 5,767,409 SH DFND 1 5,767,409 0 0
KINNATE BIOPHARMA INC COM 49705R105 13,724 345,000 SH DFND 1 345,000 0 0
KODIAK SCIENCES INC COM 50015M109 29,735 202,406 SH DFND 1 202,406 0 0
LARIMAR THERAPEUTICS INC COM 517125100 110,145 5,144,539 SH DFND 1 5,144,539 0 0
LONGVIEW ACQUISITION CORP *W EXP 05/27/202 543195119 4,833 733,333 SH DFND 1 733,333 0 0
LUMOS PHARMA INC COM 55028X109 33,435 936,291 SH DFND 1 936,291 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 17,195 1,142,552 SH DFND 1 1,142,552 0 0
MEDTECH ACQUISITION CORP UNIT 12/18/2025 58507N204 10,500 1,000,000 SH DFND 1 1,000,000 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 40,389 2,161,000 SH DFND 1 2,161,000 0 0
METACRINE INC COM 59101E103 2,181 277,469 SH DFND 1 277,469 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 60,218 3,448,912 SH DFND 1 3,448,912 0 0
MOLINA HEALTHCARE INC COM 60855R100 26,585 125,000 SH DFND 1 125,000 0 0
MONTES ARCHIMEDES ACQUISITIO UNIT 09/30/2025 612657205 21,000 2,000,000 PRN DFND 1 2,000,000 0 0
NEOS THERAPEUTICS INC COM 64052L106 201 320,993 SH DFND 1 320,993 0 0
NEURONETICS INC COM 64131A105 10,210 919,000 SH DFND 1 919,000 0 0
NEVRO CORP NOTE 1.750% 6/0 64157FAA1 208,538 115,776,000 PRN DFND 1 115,776,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 21,915 12,000,000 PRN DFND 1 12,000,000 0 0
NKARTA INC COM 65487U108 87,280 1,419,872 SH DFND 1 1,419,872 0 0
NOVAVAX INC NOTE 3.750% 2/0 670002AB0 31,326 25,000,000 SH DFND 1 25,000,000 0 0
NUVASIVE INC NOTE 2.250% 3/1 670704AG0 201,278 200,000,000 SH DFND 1 200,000,000 0 0
NUVASIVE INC COM 670704105 31,826 565,000 SH DFND 1 565,000 0 0
INVITAE CORP NOTE 2.000% 9/0 46185LAB9 263,849 163,385,000 SH DFND 1 163,385,000 0 0
OAK STR HEALTH INC COM 67181A107 58,167 951,063 SH DFND 1 951,063 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106 33,473 696,191 SH DFND 1 696,191 0 0
ONCORUS INC COM 68236R103 92,107 2,848,977 SH DFND 1 2,848,977 0 0
ORASURE TECHNOLOGIES INC COM 68554V108 22,488 2,124,515 SH DFND 1 2,124,515 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 30,021 6,949,416 SH DFND 1 6,949,416 0 0
OUTSET MED INC COM 690145107 9,947 175,000 SH DFND 1 175,000 0 0
OWENS & MINOR INC NEW COM 690732102 29,647 1,096,000 SH DFND 1 1,096,000 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 18,321 1,049,035 SH DFND 1 1,049,035 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 14,916 575,000 SH DFND 1 575,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 62,811 1,049,647 SH DFND 1 1,049,647 0 0
PACIRA BIOSCIENCES INC NOTE 2.375% 4/0 695127AD2 22,719 20,000,000 SH DFND 1 20,000,000 0 0
PANACEA ACQUISITION CORP UNIT 99/99/9999 698102209 6,381 500,000 SH DFND 1 500,000 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 11,514 187,192 SH DFND 1 187,192 0 0
PRAXIS PRECISION MEDICINES I COM 74006W108 19,257 350,000 SH DFND 1 350,000 0 0
PROFOUND MED CORP COM NEW 74319B502 14,289 695,000 SH DFND 1 695,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 27,820 1,379,971 SH DFND 1 1,379,971 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 18,948 782,670 SH DFND 1 782,670 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 18,577 14,527,000 PRN DFND 1 14,527,000 0 0
PULMONX CORP COM 745848101 31,992 463,511 SH DFND 1 463,511 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 40,627 3,959,741 SH DFND 1 3,959,741 0 0
QUIDEL CORP COM 74838J101 39,523 220,000 SH DFND 1 220,000 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 39,558 320,000 SH DFND 1 320,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 55,283 1,396,383 SH DFND 1 1,396,383 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 80,901 2,721,203 SH DFND 1 2,721,203 0 0
SARISSA CAPITAL ACQUISITN CO UNIT 10/23/2027 G7823W128 10,650 1,000,000 SH DFND 1 1,000,000 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 14,019 288,876 SH DFND 1 288,876 0 0
SELECT MED HLDGS CORP COM 81619Q105 15,628 565,000 SH DFND 1 565,000 0 0
SENIOR CONNECT ACQUISITN COR UNIT 12/09/2023 81723H207 10,290 1,000,000 SH DFND 1 1,000,000 0 0
SHATTUCK LABS INC COM 82024L103 28,826 550,000 SH DFND 1 550,000 0 0
SIENTRA INC COM 82621J105 7,461 1,918,118 SH DFND 1 1,918,118 0 0
SILK RD MED INC COM 82710M100 7,117 113,000 SH DFND 1 113,000 0 0
SOTERA HEALTH CO COM 83601L102 30,486 1,111,000 SH DFND 1 1,111,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 104,644 1,442,970 SH DFND 1 1,442,970 0 0
STRYKER CORPORATION COM 863667101 14,457 59,000 SH DFND 1 59,000 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106 6,635 250,000 SH DFND 1 250,000 0 0
TURMERIC ACQUISITION CORP UNIT 10/08/2025 G9127T116 7,703 750,000 SH DFND 1 750,000 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 10,217 83,846 SH DFND 1 83,846 0 0
VAPOTHERM INC COM 922107107 16,237 604,520 SH DFND 1 604,520 0 0
VERICEL CORP COM 92346J108 2,006 64,946 SH DFND 1 64,946 0 0
VIATRIS INC COM 92556V106 294,668 15,724,000 SH DFND 1 15,724,000 0 0
WINDTREE THERAPEUTICS INC COM 97382D303 103 20,148 SH DFND 1 20,148 0 0
XERIS PHARMACEUTICALS INC NOTE 5.000% 7/1 98422LAA5 31,658 18,000,000 PRN DFND 1 18,000,000 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 14,639 95,000 SH DFND 1 95,000 0 0


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