Lilly commits additional $4.5 billion in Indiana manufacturing sites

May 6 (Reuters) - Eli Lilly ‌said on Wednesday ​it ​would invest $4.5 billion more across two of its three manufacturing sites in Indiana, bringing the U.S. drugmaker's total capital expansion commitments ‌in the state since 2020 to more than $21 billion.

The additional ⁠investment aims to support planned production of Foundayo, Lilly's newly approved once-daily oral weight-loss ‌pill, and retatrutide, its next-generation ‌obesity candidate in late-stage development.

Since last year, global drugmakers have been ramping up U.S. manufacturing and stockpiling inventory as the Trump administration moves ​to impose 100% tariffs on branded drugs unless companies cut prices or make medicines domestically.

Lilly said the latest investment would incorporate new ⁠process designs and technologies at one of its future active pharmaceutical ingredient (API) sites and at its ​first dedicated genetic medicine manufacturing facility.

Its newly opened Lebanon Advanced Therapies facility will support both clinical and commercial production ​of genetic medicines from research-stage development through ‌large-scale commercial supply.

The site is the first of three planned on the Lebanon campus, which will also include ⁠Lilly Lebanon API and the Lilly Medicine Foundry.

"When our Lebanon API site opens in 2027, it will be the largest API production site in U.S. history, a ⁠commitment we chose to build here, at home," said CEO David Ricks.

Lilly's U.S. capital ​expansion commitments since 2020 total more than $50 billion. It plans to break ground on several of its recently announced U.S. manufacturing sites this year.

Separately, Bloomberg News reported ‌on Wednesday that Lilly is looking to sell about $8 billion of bonds as part of an effort to ‌fund its acquisition spree.

Lilly has spent more than $30 billion in deals this year, ⁠according to Dealogic data, as ‌large drugmakers look to ​diversify their portfolio and boost their pipelines ahead of upcoming patent losses.

(Reporting by Christy Santhosh in Bengaluru; Editing by ‌Shilpi Majumdar)

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