First NDIN-Completed Akkermansia muciniphila for Muscle Health: BiomeNrich™ POST M005

CHICAGO, March 26, 2025 /PRNewswire/ -- CJ BIO's BiomeNrich™ POST M005 is the first Akkermansia muciniphila-based ingredient to receive New Dietary Ingredient Notification (NDIN) acknowledgment from the U.S. Food and Drug Administration (FDA). This milestone confirms its safety and expands its potential in nutritional and functional food applications.

Akkermansia muciniphila: A Microbe with Global Recognition

Akkermansia muciniphila is well-known for its role in gut and metabolic health, with research highlighting its benefits for weight management, inflammation reduction, and metabolic disease prevention. Until now, regulatory hurdles have limited its commercial use. The FDA's acknowledgment of BiomeNrich™ POST M005 through the NDIN process ensures its safety for dietary applications, paving the way for broader industry adoption.

BiomeNrich™ POST M005: A Stable and Effective Postbiotic

BiomeNrich™ POST M005 is a postbiotic- comprised of inactivated microbes through a pasteurization process- offering enhanced stability, safety and efficacy over traditional probiotics.

A randomized, double-blind, placebo-controlled clinical trial with 92 participants over 12 weeks assessed its efficacy in supporting muscle health. The study measured improvements in muscle strength and function, showing:

• 200% increase in leg strength vs. placebo
• 130% increase in follistatin, a key muscle-supporting protein

The full study is available here: Read more

Access the white paper: Download here

CJ BIO proudly introduces BiomeNrich™ POST M005, marking a significant breakthrough in functional nutrition. CJ BIO has an exclusive global license to market M005, reinforcing its leadership in delivering innovative and science-backed solutions. "We are pleased to contribute to the growth of the nutrition industry, especially in the areas of muscle health and healthy aging," said a CJ BIO representative. "With the completion of NDI, we believe this milestone will create more opportunities for CPG brands to deliver unique and innovative products to the market using BiomeNrich™ POST M005." With regulatory approval, proven efficacy, and cutting-edge expertise, CJ BIO continues to shape the future of functional ingredients.

About CJ BIO Taste & Nutrition Business

CJ BIO is a business unit of CJ CheilJedang, a subsidiary of CJ Group, an international company founded in South Korea in 1953. CJ Group operates in the fields of Food & Food Service, Bio & Pharma, Entertainment & Media, and Retail & Logistics.

CJ BIO is a leading global supplier of fermentation-based bio-products, including an extensive line of TasteNrich^®, FlavorNrich™, AMINATURE^®, and BiomeNrich™. CJ BIO has a global network of manufacturing facilities, specializing in microbial fermentation with the highest quality and control over their ingredients. With a strong foundation in fermentation, CJ BIO combines this expertise with its commitment to innovation, delivering cutting-edge solutions for the food and nutrition industries.

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SOURCE CJ BIO