Arrowhead Research (ARWR) Acquuires RNA Assets from Roche (RHHBY)

October 24, 2011 6:28 AM EDT
Arrowhead Research Corporation (Nasdaq: ARWR), today announced that it has acquired RNA therapeutics assets from Roche (OTCBB: RHHBY) including the state-of-the-art research site in Madison, WI.

The Roche assets and IP acquired by Arrowhead include:
  • Roche Madison Inc. (formerly Mirus Bio Corporation,), providing an advanced proprietary RNAi delivery platform known as Dynamic PolyCunjugates™ (DPCs);

  • License from Tekmira Pharmaceuticals Corp. for proprietary SNALP RNAi delivery;

  • Proprietary Liposomal Nanoparticle (LNP) RNAi delivery system developed by Roche;
    License from Alnylam providing access to Alnylam’s RNAi IP and Canonical siRNA structures;

  • License from City of Hope providing access to Dicer substrate siRNA structures;

  • License from MDRNA (now Marina Biotech) providing access to Meroduplex siRNA structures; and

  • A team of over 40 leading scientists in the RNAi field and state-of-the-art facilities and infrastructure in Madison, WI.
As a result of the transaction, Arrowhead now has an array of additional delivery technologies that complement its existing delivery platforms, access to the three primary siRNA formats, and the infrastructure and team necessary to create new RNAi therapeutics and drive large industry partnerships.

Arrowhead also closed on $4 million of new funding in addition to the $6 million financing that was recently announced, providing approximately $10 million of capital. In addition, the Company entered into an agreement with Lincoln Park Capital (LPC) to provide up to $15 million to support the new operations. Under the LPC agreement, Arrowhead may, subject to customary conditions, draw all or part of the $15 million commitment at its sole discretion over a three-year period.


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