Purple Biotech Ltd. (PPBT) enters $2.3M ATM

Purple Biotech Ltd. (NASDAQ: PPBT):

We have entered into an At The Market Offering Agreement, dated September 19, 2025 (the “Sales Agreement”), with H.C. Wainwright & Co., LLC (“Wainwright”) relating to the offer and sale from time to time of American Depositary Shares (“ADSs”) offered by this prospectus supplement and the accompanying base prospectus. Each ADS represents two hundred (200) of our ordinary shares, no par value per share (“Ordinary Shares”). Under this prospectus supplement and the accompanying base prospectus, we may offer and sell ADSs having an aggregate offering price of up to $2,300,000 from time to time through or to Wainwright, acting as our agent or principal, in accordance with the Sales Agreement.

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