Form 497 Voya PARTNERS INC

VOYA PARTNERS, INC. Voya Global Insights Portfolio (the “Portfolio”)

Supplement dated December 5, 2025

to the Portfolio’s Adviser Class (“Class ADV”), Initial Class (“Class I”),

Service Class (“Class S”), and Service 2 Class (“Class S2”) Shares’

Summary Prospectus, Prospectus and Statement of Additional Information,

each dated May 1, 2025

On November 13, 2025, the Board of Trustees of the Portfolio approved a number of changes to the structure of the Portfolio that would permit the Portfolio to be sold directly to the public (the “Conversion”). Currently, the purchase and sale of shares of the Portfolio may be made only by separate accounts of insurance companies serving as investment options under variable contracts or by qualified pension or retirement plans, custodian accounts, and certain investment advisers and their affiliates, other investment companies, or permitted investors. Following the Conversion, the eligibility to invest in the Portfolio will be revised and the Portfolio will be offered directly to the public. It is expected that these changes will take effect on or about July 17, 2026 (the “Effective Date”).

No insurance company separate accounts will be invested in the Portfolio at the time of the Conversion. Please contact your insurance company for more information about how the Conversion will impact your variable contract and alternative investment options.

Qualified pension and retirement plans will remain eligible to invest in the Portfolio.

There will be no changes to the investment objective, investment strategy or investment risks of the Portfolio as a result of this Conversion.

To facilitate this Conversion, on or about the Effective Date the following changes will occur:

1.The Portfolio name will change from Voya Global Insights Portfolio to Voya Global Insights Fund.

2.Share classes will be renamed as follows:

3.The eligibility requirements for the Portfolio will change. Purchase and sales of the Portfolio will no longer be limited only to separate accounts of insurance companies serving as investment options under variable contractors or by qualified pension or retirement plans, custodian accounts, and certain investment advisers and their affiliates, other investment companies, or permitted investors. Instead, the Portfolio will be available for purchase by the general public and eligibility will vary by share class as follows:

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PLEASE RETAIN THIS SUPPLEMENT FOR FUTURE REFERENCE

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