Pharmacyclics (PCYC) Enrollment Level in RESONATE Triggers $50M Milestone

August 1, 2012 6:35 AM EDT
Pharmacyclics, Inc. (Nasdaq: PCYC) reports that the international Phase III randomized, multicenter, open-label clinical trial, RESONATEā„¢ (PCYC-1112), of ibrutinib versus ofatumumab for patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) initiated by Pharmacyclics has enrolled its fifth patient. The enrollment of the fifth patient has subsequently triggered a $50 million milestone payment obligation from Janssen Biotech, Inc. (Janssen), one of the Janssen Pharmaceutical Companies of Johnson & Johnson and the worldwide collaborator on ibrutinib in oncology.

As Pharmacyclics or Janssen initiate further Phase III trials in specific indications and enroll the 5th patient, additional milestone payments of $50 million may be triggered up to a total of $250 million.



The pharma said: "We anticipate an additional Phase III trial milestone payment during calendar 2013."


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