Athersys (ATHX) Gets U.S. Patent for non-Embryonic Stem Cell Use in Reducing GvHD

April 4, 2012 7:03 AM EDT
Athersys, Inc. (Nasdaq: ATHX) has been granted U.S. patent 8,147,824 that covers the use of non-embryonic, multipotent stem cells for the reduction in severity or prevention of Graft-versus-Host Disease (GvHD), a serious condition associated with hematopoietic stem cell transplants (HSCTs) used to treat leukemia and related conditions. Athersys recently completed a successful clinical study evaluating the adjunctive administration of MultiStem for prevention of GvHD, an indication for which the company has already received orphan drug designation.

The issued patent covers the use of MultiStem, Athersys' proprietary cell product platform, for the suppression of GvHD when administered in conjunction with an HSCT. The patent covers the administration of non-embryonic, multipotent stem cells derived from bone marrow as well as other tissues sources and applies to single or repeat dosing over a broad dose range in the context of HSCT-based treatment.


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