St. Jude (STJ) Updates on Important Quadripolar Pacing System Data at ACC 12

St. Jude Medical, Inc. (NYSE: STJ), announced key clinical findings that will be presented at ACC.12, the 61st Annual Scientific Session & Expo of the American College of Cardiology (ACC), taking place March 24 to March 27 in Chicago at the McCormick Place Convention Center.

The new data will be presented via three posters that will be on display at ACC.12. Two studies reveal that the St. Jude Medical quadripolar pacing system can improve hemodynamic function and reduce inefficiencies of the heart. A third poster showcases a registry that investigated factors associated with fluoroscopy and radiation time during cardiac resynchronization therapy (CRT) procedures.

• Benefits of Quadripolar PacingQuadripolar pacing technology, available exclusively from St. Jude Medical with the Quartet® lead, allows physicians the ability to use multisite left-ventricular (LV) pacing. The two posters below examined the role of multisite pacing in improving hemodynamics and reducing dyssynchrony (a lack of synchronization in the chambers of the heart that may lead to inefficient pumping) as compared to traditional bi-ventricular pacing.
  • Acute hemodynamic benefits of multisite left ventricular pacing in CRT recipients – This study found that in 13 patients receiving a CRT implant, all 13 patients demonstrated hemodynamic improvement as a result of multisite pacing configuration options.*
    
    
  • Multisite left ventricular pacing and acute mechanical dyssynchrony in heart failure patients – This study found that in 33 patients receiving a CRT implant, multisite pacing can reduce mechanical dyssynchrony beyond conventional bi-ventricular pacing, and may improve clinical response to CRT.
• Factors affecting radiation exposure during CRT implantation: results of the LAND-IT registry – The LAND-IT registry was a prospective, multicenter registry of patients undergoing CRT implants for standard indications. In the registry, fluoroscopy time was collected at implant, along with other relevant anatomical, demographic and procedural data. Analysis of this registry found that in real world practice, there are large variations in total fluoroscopy time for CRT implants. Increase in fluoroscopy time was not associated with baseline patient demographic characteristics, but rather the occurrence of a high capture threshold, phrenic nerve stimulation or complex cardiac anatomy. New CRT tools and strategies may help to reduce fluoroscopy time during CRT implants.

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