Bristol-Myers (BMY), Astra Zeneca (AZN) Report Positive Data for Dapagliflozin in Type 2 Diabetes Trial

December 8, 2011 6:50 AM EST
Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) report results from a Phase 3 clinical study which showed that reductions in blood sugar levels (glycosylated hemoglobin levels, or HbA1c) seen at 24 weeks with the investigational compound dapagliflozin added to existing glimepiride (sulphonylurea) therapy, compared to placebo added to glimepiride, were maintained at 48 weeks in adults with type 2 diabetes.

In addition to maintaining reductions in blood sugar levels, the 48-week study reported that patients taking dapagliflozin added to glimepiride maintained reductions in fasting plasma glucose levels (FPG), post-prandial glucose (PPG) and total body weight.


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