Wedbush Upgrades Anthera Pharma (ANTH) to Outperform; PEARL-SC Interim Analysis Shows B-Cell Reduction

December 2, 2011 7:44 AM EST
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Price: $0.00 --0%

Rating Summary:
    8 Buy, 3 Hold, 1 Sell

Rating Trend: = Flat

Today's Overall Ratings:
    Up: 13 | Down: 14 | New: 11
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Wedbush upgraded Anthera Pharma (NASDAQ: ANTH) from Neutral to Outperform, price target raised $1 to $8.

Wedbush analyst says, "Anthera announced yesterday that interim data
showed a statistically significant B-cell reduction among systemic lupus
erythematosus (SLE) patients administered A-623 in the ongoing PEARL-SC study. Recall that PEARL-SC is a randomized double-blind Phase 2b study evaluating monthly and weekly subcutaneous A-623 for SLE with a primary endpoint of clinical improvement according to the SLE responder index at 24 weeks. Also recall that A-623 is an inhibitor of B-cell activating factor (BAFF), and B-cell proliferation is associated with SLE. While there is strong evidence to suggest that lowering B-cell activity is key to treating SLE (demonstrated by HGSI’s Benlysta), the lupus drug development space is littered with failed treatments that have reduced B-cells but did not demonstrate significant improvements in SLE disease activity (examples are Rituxan and Atacicept)."

For an analyst ratings summary and ratings history on Anthera Pharma click here. For more ratings news on Anthera Pharma click here.

Shares of Anthera Pharma closed at $5.79 yesterday.


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