Enzon Pharmaceuticals (ENZN) Announces Plans to Offer Clinical and Preclinical Data on mRNA Antagonists at 2011 AACR-NCI-EORTC Meeting
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Enzon Pharmaceuticals, Inc. (NASDAQ: ENZN) today announced the presentation of clinical and preclinical data from three messenger ribonucleic acid (mRNA) product candidates based on the Company's locked nucleic acid (LNA) technology platform at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics in San Francisco, CA.
Enzon's LNA oligonucleotides, which reach their mRNA target without a delivery mechanism, unlike most RNA approaches, target difficult-to-drug pathways with well-established links to cancer survival, proliferation and drug resistance. These unique targets include hypoxia inducible factor-1a (HIF-1a), survivin, androgen receptor, HER3 and �-catenin. "The current data further elucidate the strengths of our third-generation LNA platform, including its ability to safely and effectively target important pathways in oncology using antisense molecules," said Aby Buchbinder, M.D., Enzon's Vice President of Clinical Development.
Enzon's LNA oligonucleotides, which reach their mRNA target without a delivery mechanism, unlike most RNA approaches, target difficult-to-drug pathways with well-established links to cancer survival, proliferation and drug resistance. These unique targets include hypoxia inducible factor-1a (HIF-1a), survivin, androgen receptor, HER3 and �-catenin. "The current data further elucidate the strengths of our third-generation LNA platform, including its ability to safely and effectively target important pathways in oncology using antisense molecules," said Aby Buchbinder, M.D., Enzon's Vice President of Clinical Development.
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