UPDATE - Canaccord Genuity Downgraded Tranzyme (TZYM) to Hold; Moving to Sidelines After First Uli Phase 3 Miss

March 13, 2012 8:32 AM EDT
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Price: $0.48 --0%

Rating Summary:
    3 Buy, 3 Hold, 0 Sell

Rating Trend: = Flat

Today's Overall Ratings:
    Up: 8 | Down: 6 | New: 26
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UPDATE - Canaccord Genuity downgraded Tranzyme (NASDAQ: TZYM) from Buy to Hold, price target cut from $7 to $3.

Analyst, Ritu Baral, said, "Lowering rating and price target after first ulimorelin Phase 3 ULISES trial misses its primary endpoint. We are lowering our rating based on negative data from the first pivotal trial of TZYM lead drug ulimorelin (uli) in POI, which we think augurs poorly for upcoming Q2/12 data from the second uli pivotal trial. Our valuation is now driven by the potential of Phase 2 candidate TZP-102."

"We are staying on the sidelines until next uli Phase 3 reads out, and more detail gives clarity into read--through to TZP--102. We expect the second uli phase 3 trial to also miss and await detailed data (e.g., nausea, vomiting), which may represent positive 102 read-through."

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