Canaccord Genuity reiterates a 'Buy' on Aegerion Pharmaceuticals (AEGR); 78-Week Extension Data: Durable Lomitapide Efficacy, Safety

January 9, 2012 8:52 AM EST
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Canaccord Genuity reiterates a 'Buy' on Aegerion Pharmaceuticals (NASDAQ: AEGR) price target of $24.00.

Canaccord analyst, Ritu Baral, said, "Reiterate rating and price target on lomitapide potential as best-in-class HoFH drug. Lomitapide is AEGR’s Phase 3 drug for HoFH, a rare genetic disease that causes extremely high LDLs. We think lomitapide is the best-in-class HoFH drug in terms of tolerability and efficacy vs. ISIS/SNY’s Phase 3 mipomersen. AEGR will submit lomitapide’s NDA/MAA in Q1/12, and we expect FDA approval in Q3/12.x"

"Last Friday’s 78--week lomitapide pivotal extension data showed steady safety and efficacy in HoFH (Fig. 1). Mean LDL baseline reduction at week 78 was slightly lower at 38% (vs. 44% at week 56). Mean liver fat, lomitapide’s main safety concern, was slightly higher at 8.2% (vs. 7.3% at Tx week 56), but still lower than peak (9.0% at Tx week 26). We think this variation is minor with little clinical meaningfulness."

For an analyst ratings summary and ratings history on Aegerion Pharmaceuticals click here. For more ratings news on Aegerion Pharmaceuticals click here.

Shares of Aegerion Pharmaceuticals closed at $16.11 yesterday.


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