Disc Medicine (IRON) PT Raised to $100 at Leerink Partners, 'one of our Top Picks for 2025'

Leerink Partners analyst Thomas Smith raised the price target on Disc Medicine (NASDAQ: IRON) to $100.00 (from $85.00) while maintaining a Outperform rating.

The analyst comments "We see positive readthrough and derisking for IRON’s (OP) lead program bitopertin (bito, oral GlyT1 inhibitor) in EPP, following the receipt of FDA’s new Commissioner’s National Priority Voucher (CNPV) announced this afternoon. Importantly, we believe the CNPV reflects the FDA’s positive view of bitopertin's NDA submitted at the end of September (see our notes HERE and HERE), recognizing both the quality of the data generated to date and the substantial unmet medical need for a disease-modifying therapy for EPP patients. We see this CNPV as de-risking for the review, and potentially enabling an accelerated timeline to approval and launch – with FDA guidance suggesting a review may be condensed to just ~1-2 months following submission vs. standard 10-12 months. This expedited timeline could enable bito accelerated approval by YE25 – well-ahead of current mid-2026 expectations. Based on this encouraging development, we are increasing our probability of success (POS) for bito in EPP to 95% (from 70%) and raising our PT to $100 (from $85). We remain encouraged by IRON’s continued clinical and regulatory execution, as evidenced by bito’s streamlined regulatory path in EPP that we expect will accelerate time to commercialization while unlocking meaningful value for IRON shares. We look forward to the potential regulatory decision for bito in EPP in the coming months, as well as upcoming clinical data updates for DISC-0974 (anti-HJV antibody) in MF (likely ASH in December) and NDD-CKD (potentially ASN in Nov or ASH in Dec). IRON is one of our Top Picks for 2025; Reiterate OP."

You May Also Be Interested In

• Bullish (BLSH) PT Raised to $30 at Compass Point
• York Space Systems (YSS) PT Lowered to $18 at Needham
• Nu Holdings (Nubank) (NU) PT Raised to $19 at Needham