Cantor Fitzgerald Reiterates Neutral Rating on Alnylam Pharmaceuticals (ALNY)

March 21, 2025 6:47 AM EDT
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Price: $226.50 -0.27%

Rating Summary:
    29 Buy, 12 Hold, 1 Sell

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Today's Overall Ratings:
    Up: 13 | Down: 14 | New: 11
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Cantor Fitzgerald analyst Olivia Brayer reiterated a Neutral rating and $250.00 price target on Alnylam Pharmaceuticals (NASDAQ: ALNY).

The analyst commented, “An hour and a half later...and we finally have access to the updated label (but still no PR)! Amvuttra is now officially approved for ATTR-CM, and a few days before Sunday's PDUFA date (most were expecting it to hit tomorrow, not today [03/20]). The most important thing is that it's approved with a broad label: by this, we mean mortality language is in fact included on the front page.”

“This had become a bit of a debate, but most were expecting it (including us). Here's the exact language: "the cardiomyopathy of wild- type or hereditary transthyretin-mediated amyloidosis in adults to reduce cardiovascular mortality, cardiovascular hospitalizations and urgent heart failure visits".

“The "urgent heart failure visits" part is actually a differentiator vs. the other products on the market. Neither one has it in their respective labels: Attruby label, Vyndamax label. Nothing stands out to us in terms of the stats (Table 4) or All-Cause Mortality curves (Figure 5) - other than the fact that it's only out to 33 months, but that's not surprising given the PFE (NC)/BBIO (OW, covered by J. Schimmer) comps.”

For an analyst ratings summary and ratings history on Alnylam Pharmaceuticals click here. For more ratings news on Alnylam Pharmaceuticals click here.

Shares of Alnylam Pharmaceuticals closed at $253.55 yesterday.



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