Morning Movers 11/16: SPEX, NLST, XJT, NABI, KHD, IBKC, SPA Higher; PARD, CRXX, CAEI Lower Nov 16, 2009 10:11AM

Poniard Pharmaceuticals, Inc. (NASDAQ: PARD) 77% LOWER; today announced that its pivotal Phase 3 SPEAR (Study of Picoplatin Efficacy After Relapse) trial of picoplatin in the second-line treatment of small cell lung cancer did not meet its primary endpoint of overall survival. The analysis, based on 320 evaluable events (patient deaths), showed a hazard ratio of 0.82 with a p value of 0.089. The stock was also downgraded at Merriman Curhan Ford.

Spherix Incorporated (NASDAQ: SPEX) 72% HIGHER; today announced positive interim Phase 3 clinical results for the planned review of the NEET (Naturlose (D-tagatose) Efficacy Evaluation Trial) trial of D-tagatose in drug naive patients. Click here to see the full report.

CombinatoRx, Incorporated (NASDAQ: CRXX) 39.3% LOWER; CRXX and Neuromed Pharmaceuticals Inc. today announced that on November 13, 2009, representatives of Neuromed discussed the pending New Drug Application for the product candidate EXALGO^TM (hydromorphone HCl extended release) ...