Regeneron (REGN) Reports Evkeeza Phase 3 Trial Demonstrated 48% LDL-C Reduction in Children with Ultra-rare Form of High Cholesterol
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Evkeeza® (evinacumab) Phase 3 Trial Demonstrates 48% LDL-C Reduction in Children with Ultra-rare Form of High Cholesterol
May 21, 2022 7:00 AM EDTTARRYTOWN, N.Y., May 21, 2022 /PRNewswire/ --
Children already on other lipid-lowering therapies entered the trial with dangerously high LDL-C (264 mg/dL on average), and 79% saw their LDL-C reduced by at least half at 24 weeks
FDA submission planned by end of 2022
Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced positive results from a Phase 3 trial evaluating Evkeeza® (evinacumab) in children aged 5 to 11 with homozygous familial hypercholesterolemia (HoFH). The trial met its primary endpoint, showing children who added investigational Evkeeza to other lipid-lowering therapies reduced... More