Orphazyme A/S (ORPH) falls as trial of arimoclomol for Inclusion Body Myositis fails to met Primary and Secondary Endpoints
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Orphazyme announces topline results from pivotal trial of arimoclomol for Inclusion Body Myositis (IBM)
March 29, 2021 1:00 AM EDTOrphazyme A/SCompany announcement                                            No. 12/2021Inside informationCompany Registration No. 32266355
Copenhagen March 29, 2021 Orphazyme A/S [ORPHA.CO (DK); ORPH (US)], a late-stage biopharmaceutical company pioneering the heat shock protein response for the treatment of neurodegenerative rare diseases, today announced its phase 2/3 trial evaluating arimoclomol for the treatment of inclusion body myositis (IBM), a progressively debilitating muscle-wasting disease, did not meet its primary and secondary endpoints. The primary goal was to evaluate the treatment effect on disease progression as measured by the inclusion body myositis functional rating scale (IBMFRS).
The randomized, placebo-controlled trial... More