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Merck's (MRK) Grazoprevir/Elbasvir HCV Regimen Receives Two FDA Breakthrough Therapy Designations

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Gilead (GILD), AbbVie (ABBV) Buy Ratings Maintained at Deutsche Bank Following Merck (MRK) HCV Data

April 8, 2015 9:15 AM EDT

Deutsche Bank maintained Buy rating on Gilead Sciences (NASDAQ: GILD) and AbbVie (NYSE: ABBV) following Merck (NYSE: MRK) phase 3 data HCV data. In the view of analyst Robyn Karnauskas, data... More

Advaxis (ADXS), Merck (MRK) Commence KEYNOTE-046 Enrollment

April 8, 2015 7:36 AM EDT

Advaxis (NASDAQ: ADXS) and Merck (NYSE: MRK) announced that enrollment has initiated in the Phase 1/2 clinical trial evaluating the combination of ADXS-PSA (ADXS31-142), an investigational Lm-LLO immunotherapy, and KEYTRUDA® (pembrolizumab), the first anti-PD-1 (programmed death receptor-1) therapy approved in the United States, in patients with previously treated, metastatic castration-resistant prostate cancer (mCRPC). The clinical trial, KEYNOTE-046, is the first-in-human study of Advaxis's lead Lm-LLO immunotherapy candidate for prostate cancer. It is the second study initiated to evaluate the use of KEYTRUDA in the treatment of... More