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Shire plc (SHPG) to Update on R&D Pipeline at Investor Day; Enters Collaboration with CFFT

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PTC Therapeutics (PTCT) Gains on Takeover Speculation

December 9, 2014 12:25 PM EST

PTC Therapeutics (NASDAQ: PTCT) gains on takeover speculation after DealReporter said Shire plc (NASDAQ: SHPG)
and Sanofi (NYSE: SNY) are potential suitors for the company.

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BofA/Merrill Lynch Downgrades Shire (SHPG) to Neutral

December 9, 2014 6:26 AM EST

BofA/Merrill Lynch downgraded Shire (NASDAQ: SHPG) from Buy to Neutral with a price target of $226.00 (from $220.00) on a more balanced risk/reward.

Analyst Graham Parry cited: "(1) we believe Shires growth potential is now widely recognised (most sellside Buys in sector... More

Sangamo Biosciences (SGMO) Issues Encouraging Update on IVPRP as LSD, Hemophilia Treatment

December 8, 2014 7:11 AM EST

Sangamo Biosciences (Nasdaq: SGMO) announced the presentation of new preclinical data from its proprietary programs for the treatment of lysosomal storage disorders (LSD) and Shire-partnered hemophilia program. These studies demonstrate the broad applicability of Sangamo's In Vivo Protein Replacement Platform (IVPRP) for the potentially curative treatment of such diseases, and were presented at the 56th Annual Meeting of the American Society of Hematology (ASH) held in San Francisco from December 5 to 9, 2014.

The data presented at ASH from Sangamo's proprietary IVPRP applications demonstrated the efficient production, secretion and tissue uptake of functional iduronate-2-sulfatase and... More