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   <title>Beacon Therapeutics reports positive 12-month data for XLRP gene therapy</title>
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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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   <title>Beacon Therapeutics reports positive 12-month data for XLRP gene therapy</title>
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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

&lt;p&gt;Laru-zova was generally</description>
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   <title>Beacon Therapeutics reports positive 12-month data for XLRP gene therapy</title>
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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

&lt;p&gt;Laru-zova was generally</description>
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   <title>Beacon Therapeutics reports positive 12-month data for XLRP gene therapy</title>
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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

&lt;p&gt;Laru-zova was generally</description>
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   <title>Beacon Therapeutics reports positive 12-month data for XLRP gene therapy</title>
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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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   <title>Beacon Therapeutics reports positive 12-month data for XLRP gene therapy</title>
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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;p&gt;Beacon Therapeutics Holdings Limited announced 12-month safety and efficacy data from its Phase 2 DAWN trial of laruparetigene zovaparvovec (laru-zova) in patients with X-linked retinitis pigmentosa at the Association for Research in Vision and Ophthalmology Annual Meeting.&lt;/p&gt;

&lt;p&gt;The data showed sustained improvements in visual function measures, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry. Among participants who received a high dose, 50% achieved at least a 2-line improvement from baseline, while 25% achieved at least a 3-line improvement. For the low dose group, 67% of participants achieved at least a 2-line improvement from baseline.&lt;/p&gt;

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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;Data show promising and sustained improvements across key measures of visual function, including low luminance visual acuity and mean macular sensitivity as measured by microperimetry.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Laru-zova was generally well-tolerated through month 12, with data supporting ongoing clinical development for the treatment of patients with XLRP caused by mutations in the RPGR gene.&lt;/li&gt;&lt;li style=&quot;text-align:justify;&quot;&gt;Beacon remains on track to report topline data from the pivotal VISTA trial of laru-zova in the second half of 2026.&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p align=&quot;justify&quot;&gt;LONDON and CAMBRIDGE, Mass., May  07, 2026  (GLOBE NEWSWIRE) -- Beacon Therapeutics Holdings Limited (Beacon Therapeutics or the Company), a leading clinical-stage</description>
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