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   <title>Spero Therapeutics to Participate in the Chardan 10th Annual Healthcare Conference</title>
   <link>http://www.streetinsider.com/Press+Releases/Spero+Therapeutics+to+Participate+in+the+Chardan+10th+Annual+Healthcare+Conference/27193335.html</link>
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&lt;p&gt;CAMBRIDGE, Mass., Oct.  15, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=w2sVKY3vfqRF20UQYV19NRe5plb1RuOkAMh-2_2YcSeKn5Zkydr5PRIvxb27YMDbW8lYk2bzYTvudMewjqoCXBytBEhbPwgowHGZtuzaNN8=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and inflammation, today announced that Esther Rajavelu, Spero&amp;apos;s President and Chief Executive Officer, will participate in a fireside chat at the Chardan 10th Annual Healthcare Conference to be held in New York City, on October 20th, 2026. Spero&amp;apos;s leadership team will also be available for one-on-one meetings at the conference.&lt;/p&gt; &lt;table style=&quot;border-collapse: collapse; width:100%; border-collapse:collapse ;&quot;&gt;&lt;tr&gt;&lt;td style=&quot;max-width:20%; width:20%; min-width:20%;;vertical-align: bottom ; &quot;&gt;&lt;strong&gt;Presentation Details&lt;/strong&gt;&lt;/td&gt;&lt;td style=&quot;max-width:80%; width:80%; min-width:80%;;vertical-align: bottom ; &quot;&gt; &lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style=&quot;vertical-align:</description>
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   <pubDate>Thu, 15 Oct 2026 16:05:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">SPRO</category>
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   <title>Spero Therapeutics to Participate in the Chardan 10th Annual Healthcare Conference</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Spero+Therapeutics+to+Participate+in+the+Chardan+10th+Annual+Healthcare+Conference/27193335.html</link>
   <description>
&lt;p&gt;CAMBRIDGE, Mass., Oct.  15, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=w2sVKY3vfqRF20UQYV19NRe5plb1RuOkAMh-2_2YcSeKn5Zkydr5PRIvxb27YMDbW8lYk2bzYTvudMewjqoCXBytBEhbPwgowHGZtuzaNN8=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and inflammation, today announced that Esther Rajavelu, Spero&amp;apos;s President and Chief Executive Officer, will participate in a fireside chat at the Chardan 10th Annual Healthcare Conference to be held in New York City, on October 20th, 2026. Spero&amp;apos;s leadership team will also be available for one-on-one meetings at the conference.&lt;/p&gt; &lt;table style=&quot;border-collapse: collapse; width:100%; border-collapse:collapse ;&quot;&gt;&lt;tr&gt;&lt;td style=&quot;max-width:20%; width:20%; min-width:20%;;vertical-align: bottom ; &quot;&gt;&lt;strong&gt;Presentation Details&lt;/strong&gt;&lt;/td&gt;&lt;td style=&quot;max-width:80%; width:80%; min-width:80%;;vertical-align: bottom ; &quot;&gt; &lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td style=&quot;vertical-align:</description>
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   <pubDate>Thu, 15 Oct 2026 16:05:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">SPRO</category>
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   <title>Spero Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)</title>
   <link>http://www.streetinsider.com/Press+Releases/Spero+Therapeutics+Announces+Inducement+Grants+Under+Nasdaq+Listing+Rule+5635%28c%29%284%29/27142078.html</link>
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&lt;p&gt;CAMBRIDGE, Mass., Oct.  02, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=1JCLLq_7GltKfODHgbYVJuBqtVC8EKM-bkO1xHKCXT5IhDcjNd0hnNyJEE7W_Oq1s0lF004Y_H0ixWigLYzBlh5JbG4FKOhTw-8KkSk2tsY=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and inflammation, today announced that the Compensation Committee of Spero’s Board of Directors approved grants, made on October 1, 2026, of an aggregate of 233,000 restricted stock unit awards (RSUs) and 323,000 stock options to new employees under the Spero Therapeutics, Inc. 2019 Inducement Equity Incentive Plan, as amended (2019 Inducement Plan). The stock options and RSUs are being granted as an inducement material to Spero’s new employees in accordance</description>
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   <pubDate>Fri, 02 Oct 2026 16:05:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">SPRO</category>
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   <title>Spero Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Spero+Therapeutics+Announces+Inducement+Grants+Under+Nasdaq+Listing+Rule+5635%28c%29%284%29/27142078.html</link>
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&lt;p&gt;CAMBRIDGE, Mass., Oct.  02, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=1JCLLq_7GltKfODHgbYVJuBqtVC8EKM-bkO1xHKCXT5IhDcjNd0hnNyJEE7W_Oq1s0lF004Y_H0ixWigLYzBlh5JbG4FKOhTw-8KkSk2tsY=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and inflammation, today announced that the Compensation Committee of Spero’s Board of Directors approved grants, made on October 1, 2026, of an aggregate of 233,000 restricted stock unit awards (RSUs) and 323,000 stock options to new employees under the Spero Therapeutics, Inc. 2019 Inducement Equity Incentive Plan, as amended (2019 Inducement Plan). The stock options and RSUs are being granted as an inducement material to Spero’s new employees in accordance</description>
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   <pubDate>Fri, 02 Oct 2026 16:05:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">SPRO</category>
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   <title>Spero Therapeutics (SPRO) PT Raised to $6 at H.C. Wainwright</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Spero+Therapeutics+%28SPRO%29+PT+Raised+to+%246+at+H.C.+Wainwright/27055119.html</link>
   <description>&lt;p&gt;H.C. Wainwright analyst Raghuam Selvaraju raised the price target on Spero Therapeutics (NASDAQ: SPRO) to $6.00 (from $5.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;Resetting around an in-licensed I&amp;I asset—raising price target. In mid-July 2026, Spero Therapeutics announced an exclusive license agreement on IBI355 (Spero R&amp;D code: SP001), a third-generation Fc-silent anti-CD40L antibody, from Innovent Biologics (1801.HK; not rated), a publicly-traded, China-based biotechnology company. Spero holds exclusive rights to develop, research, manufacture, and commercialize IBI355 worldwide, excluding Greater China, where Innovent retains rights. Currently, Spero expects to advance IBI355 into a Phase 2 study in IgG4-related disease (IgG4-RD) patients</description>
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   <pubDate>Mon, 14 Sep 2026 06:56:25 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">SPRO</category>
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   <title>Spero Therapeutics (SPRO) PT Raised to $6 at H.C. Wainwright</title>
   <link>http://www.streetinsider.com/Analyst+Comments/Spero+Therapeutics+%28SPRO%29+PT+Raised+to+%246+at+H.C.+Wainwright/27055119.html</link>
   <description>&lt;p&gt;H.C. Wainwright analyst Raghuam Selvaraju raised the price target on Spero Therapeutics (NASDAQ: SPRO) to $6.00 (from $5.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;Resetting around an in-licensed I&amp;I asset—raising price target. In mid-July 2026, Spero Therapeutics announced an exclusive license agreement on IBI355 (Spero R&amp;D code: SP001), a third-generation Fc-silent anti-CD40L antibody, from Innovent Biologics (1801.HK; not rated), a publicly-traded, China-based biotechnology company. Spero holds exclusive rights to develop, research, manufacture, and commercialize IBI355 worldwide, excluding Greater China, where Innovent retains rights. Currently, Spero expects to advance IBI355 into a Phase 2 study in IgG4-related disease (IgG4-RD) patients</description>
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   <pubDate>Mon, 14 Sep 2026 06:56:25 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">SPRO</category>
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   <title>Form  EFFECT     Spero Therapeutics, Inc.             </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++EFFECT+++++Spero+Therapeutics%2C+Inc.+++++++++++++/27050465.html</link>
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   <pubDate>Fri, 11 Sep 2026 06:03:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">SPRO</category>
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   <title>Form  8-K        Spero Therapeutics, Inc.  For: Aug 28</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Spero+Therapeutics%2C+Inc.++For%3A+Aug+28/26999170.html</link>
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   <pubDate>Fri, 28 Aug 2026 17:26:00 -0400</pubDate>
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   <title>Form  8-K        Spero Therapeutics, Inc.  For: Aug 28</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Spero+Therapeutics%2C+Inc.++For%3A+Aug+28/26999170.html</link>
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   <pubDate>Fri, 28 Aug 2026 17:26:00 -0400</pubDate>
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   <title>Form  S-3        Spero Therapeutics, Inc.             </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++S-3++++++++Spero+Therapeutics%2C+Inc.+++++++++++++/26998952.html</link>
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   <pubDate>Fri, 28 Aug 2026 17:04:00 -0400</pubDate>
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   <title>Form  S-3        Spero Therapeutics, Inc.             </title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++S-3++++++++Spero+Therapeutics%2C+Inc.+++++++++++++/26998952.html</link>
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   <pubDate>Fri, 28 Aug 2026 17:04:00 -0400</pubDate>
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   <title>SmartPros Ltd. (SPRO) Tops Q2 EPS by 1c</title>
   <link>http://www.streetinsider.com/Earnings/SmartPros+Ltd.+%28SPRO%29+Tops+Q2+EPS+by+1c/26913679.html</link>
   <description>&lt;p&gt;SmartPros Ltd. (NASDAQ: SPRO) reported Q2 EPS of ($0.16), $0.01 better than the analyst estimate of ($0.17).&lt;/p&gt;&lt;p&gt;For earnings history and earnings-related data on SmartPros Ltd. (SPRO) &lt;a href=&quot;http://www.streetinsider.com/ec_earnings.php?q=SPRO&quot;&gt;click here&lt;/a&gt;.&lt;/p&gt;</description>
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   <pubDate>Wed, 12 Aug 2026 16:41:03 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">SPRO</category>
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   <title>Form  8-K        Spero Therapeutics, Inc.  For: Aug 12</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Spero+Therapeutics%2C+Inc.++For%3A+Aug+12/26912899.html</link>
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   <pubDate>Wed, 12 Aug 2026 16:09:00 -0400</pubDate>
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   <title>Form  8-K        Spero Therapeutics, Inc.  For: Aug 12</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++Spero+Therapeutics%2C+Inc.++For%3A+Aug+12/26912899.html</link>
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   <pubDate>Wed, 12 Aug 2026 16:09:00 -0400</pubDate>
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   <title>Form  10-Q       Spero Therapeutics, Inc.  For: Jun 30</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++10-Q+++++++Spero+Therapeutics%2C+Inc.++For%3A+Jun+30/26912640.html</link>
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   <pubDate>Wed, 12 Aug 2026 16:03:00 -0400</pubDate>
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   <title>Form  10-Q       Spero Therapeutics, Inc.  For: Jun 30</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++10-Q+++++++Spero+Therapeutics%2C+Inc.++For%3A+Jun+30/26912640.html</link>
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   <pubDate>Wed, 12 Aug 2026 16:03:00 -0400</pubDate>
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   <title>Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update</title>
   <link>http://www.streetinsider.com/Press+Releases/Spero+Therapeutics+Announces+Second+Quarter+2026+Operating+Results+and+Provides+Business+Update/26912545.html</link>
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&lt;ul&gt;&lt;li&gt;&lt;em&gt;Entered an exclusive license agreement with Innovent Biologics for SP001, a Phase 2-ready, third-generation anti-CD40L antibody for immune-mediated diseases &lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;U.S. Food and Drug Administration approved Utebzi™ (tebipenem pivoxil), the first and only oral carbapenem antibiotic for adults with complicated urinary tract infections (cUTIs), including pyelonephritis&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Closed $105 million non-recourse, non-dilutive financing backed by a portion of future Utebzi milestones and royalties, extending cash runway into the second half of 2029&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Appointed Debra Zack, M.D., Ph.D., as Chief Medical Officer&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Conference call today at 5pm EDT&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., Aug.  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=W1DlfOHlVyo8YzCg2TmppyjFbxzTUt00MIsZjOFdaAuYC4nB9yYp-jy9dgkB7UrMbwTWJQzeC0qeCyueBFcZbZIoVOx7NYP9Oq8YAyoM4jE=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq:</description>
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   <pubDate>Wed, 12 Aug 2026 16:01:00 -0400</pubDate>
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   <title>Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update</title>
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&lt;ul&gt;&lt;li&gt;&lt;em&gt;Entered an exclusive license agreement with Innovent Biologics for SP001, a Phase 2-ready, third-generation anti-CD40L antibody for immune-mediated diseases &lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;U.S. Food and Drug Administration approved Utebzi™ (tebipenem pivoxil), the first and only oral carbapenem antibiotic for adults with complicated urinary tract infections (cUTIs), including pyelonephritis&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Closed $105 million non-recourse, non-dilutive financing backed by a portion of future Utebzi milestones and royalties, extending cash runway into the second half of 2029&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Appointed Debra Zack, M.D., Ph.D., as Chief Medical Officer&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Conference call today at 5pm EDT&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., Aug.  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=W1DlfOHlVyo8YzCg2TmppyjFbxzTUt00MIsZjOFdaAuYC4nB9yYp-jy9dgkB7UrMbwTWJQzeC0qeCyueBFcZbZIoVOx7NYP9Oq8YAyoM4jE=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq:</description>
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   <title>Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update</title>
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&lt;ul&gt;&lt;li&gt;&lt;em&gt;Entered an exclusive license agreement with Innovent Biologics for SP001, a Phase 2-ready, third-generation anti-CD40L antibody for immune-mediated diseases &lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;U.S. Food and Drug Administration approved Utebzi™ (tebipenem pivoxil), the first and only oral carbapenem antibiotic for adults with complicated urinary tract infections (cUTIs), including pyelonephritis&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Closed $105 million non-recourse, non-dilutive financing backed by a portion of future Utebzi milestones and royalties, extending cash runway into the second half of 2029&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Appointed Debra Zack, M.D., Ph.D., as Chief Medical Officer&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Conference call today at 5pm EDT&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., Aug.  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=W1DlfOHlVyo8YzCg2TmppyjFbxzTUt00MIsZjOFdaAuYC4nB9yYp-jy9dgkB7UrMbwTWJQzeC0qeCyueBFcZbZIoVOx7NYP9Oq8YAyoM4jE=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq:</description>
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   <pubDate>Wed, 12 Aug 2026 16:01:00 -0400</pubDate>
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   <title>Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update</title>
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&lt;ul&gt;&lt;li&gt;&lt;em&gt;Entered an exclusive license agreement with Innovent Biologics for SP001, a Phase 2-ready, third-generation anti-CD40L antibody for immune-mediated diseases &lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;U.S. Food and Drug Administration approved Utebzi™ (tebipenem pivoxil), the first and only oral carbapenem antibiotic for adults with complicated urinary tract infections (cUTIs), including pyelonephritis&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Closed $105 million non-recourse, non-dilutive financing backed by a portion of future Utebzi milestones and royalties, extending cash runway into the second half of 2029&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Appointed Debra Zack, M.D., Ph.D., as Chief Medical Officer&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Conference call today at 5pm EDT&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., Aug.  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=W1DlfOHlVyo8YzCg2TmppyjFbxzTUt00MIsZjOFdaAuYC4nB9yYp-jy9dgkB7UrMbwTWJQzeC0qeCyueBFcZbZIoVOx7NYP9Oq8YAyoM4jE=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq:</description>
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   <pubDate>Wed, 12 Aug 2026 16:01:00 -0400</pubDate>
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   <title>Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update</title>
   <link>http://www.streetinsider.com/Press+Releases/Spero+Therapeutics+Announces+Second+Quarter+2026+Operating+Results+and+Provides+Business+Update/26912545.html</link>
   <description>
&lt;ul&gt;&lt;li&gt;&lt;em&gt;Entered an exclusive license agreement with Innovent Biologics for SP001, a Phase 2-ready, third-generation anti-CD40L antibody for immune-mediated diseases &lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;U.S. Food and Drug Administration approved Utebzi™ (tebipenem pivoxil), the first and only oral carbapenem antibiotic for adults with complicated urinary tract infections (cUTIs), including pyelonephritis&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Closed $105 million non-recourse, non-dilutive financing backed by a portion of future Utebzi milestones and royalties, extending cash runway into the second half of 2029&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Appointed Debra Zack, M.D., Ph.D., as Chief Medical Officer&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Conference call today at 5pm EDT&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., Aug.  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=W1DlfOHlVyo8YzCg2TmppyjFbxzTUt00MIsZjOFdaAuYC4nB9yYp-jy9dgkB7UrMbwTWJQzeC0qeCyueBFcZbZIoVOx7NYP9Oq8YAyoM4jE=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq:</description>
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   <title>Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Spero+Therapeutics+Announces+Second+Quarter+2026+Operating+Results+and+Provides+Business+Update/26912545.html</link>
   <description>
&lt;ul&gt;&lt;li&gt;&lt;em&gt;Entered an exclusive license agreement with Innovent Biologics for SP001, a Phase 2-ready, third-generation anti-CD40L antibody for immune-mediated diseases &lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;U.S. Food and Drug Administration approved Utebzi™ (tebipenem pivoxil), the first and only oral carbapenem antibiotic for adults with complicated urinary tract infections (cUTIs), including pyelonephritis&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Closed $105 million non-recourse, non-dilutive financing backed by a portion of future Utebzi milestones and royalties, extending cash runway into the second half of 2029&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Appointed Debra Zack, M.D., Ph.D., as Chief Medical Officer&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Conference call today at 5pm EDT&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., Aug.  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=W1DlfOHlVyo8YzCg2TmppyjFbxzTUt00MIsZjOFdaAuYC4nB9yYp-jy9dgkB7UrMbwTWJQzeC0qeCyueBFcZbZIoVOx7NYP9Oq8YAyoM4jE=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq:</description>
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   <title>Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update</title>
   <link>http://www.streetinsider.com/Press+Releases/Spero+Therapeutics+Announces+Second+Quarter+2026+Operating+Results+and+Provides+Business+Update/26912545.html</link>
   <description>
&lt;ul&gt;&lt;li&gt;&lt;em&gt;Entered an exclusive license agreement with Innovent Biologics for SP001, a Phase 2-ready, third-generation anti-CD40L antibody for immune-mediated diseases &lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;U.S. Food and Drug Administration approved Utebzi™ (tebipenem pivoxil), the first and only oral carbapenem antibiotic for adults with complicated urinary tract infections (cUTIs), including pyelonephritis&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Closed $105 million non-recourse, non-dilutive financing backed by a portion of future Utebzi milestones and royalties, extending cash runway into the second half of 2029&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Appointed Debra Zack, M.D., Ph.D., as Chief Medical Officer&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Conference call today at 5pm EDT&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., Aug.  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=W1DlfOHlVyo8YzCg2TmppyjFbxzTUt00MIsZjOFdaAuYC4nB9yYp-jy9dgkB7UrMbwTWJQzeC0qeCyueBFcZbZIoVOx7NYP9Oq8YAyoM4jE=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq:</description>
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   <title>Spero Therapeutics Announces Second Quarter 2026 Operating Results and Provides Business Update</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Spero+Therapeutics+Announces+Second+Quarter+2026+Operating+Results+and+Provides+Business+Update/26912545.html</link>
   <description>
&lt;ul&gt;&lt;li&gt;&lt;em&gt;Entered an exclusive license agreement with Innovent Biologics for SP001, a Phase 2-ready, third-generation anti-CD40L antibody for immune-mediated diseases &lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;U.S. Food and Drug Administration approved Utebzi™ (tebipenem pivoxil), the first and only oral carbapenem antibiotic for adults with complicated urinary tract infections (cUTIs), including pyelonephritis&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Closed $105 million non-recourse, non-dilutive financing backed by a portion of future Utebzi milestones and royalties, extending cash runway into the second half of 2029&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Appointed Debra Zack, M.D., Ph.D., as Chief Medical Officer&lt;/em&gt;&lt;/li&gt;&lt;li&gt;&lt;em&gt;Conference call today at 5pm EDT&lt;/em&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., Aug.  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=W1DlfOHlVyo8YzCg2TmppyjFbxzTUt00MIsZjOFdaAuYC4nB9yYp-jy9dgkB7UrMbwTWJQzeC0qeCyueBFcZbZIoVOx7NYP9Oq8YAyoM4jE=&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Spero Therapeutics, Inc.&lt;/a&gt; (Nasdaq:</description>
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   <title>Form  3          Spero Therapeutics, Inc.  For: Aug 03  Filed by: Zack Debra</title>
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   <pubDate>Wed, 12 Aug 2026 11:03:00 -0400</pubDate>
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