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   <title>Form  SCHEDULE 13G/A  SCYNEXIS INC                           Filed by: FEDERATED HERMES, INC.</title>
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   <title>Form  SCHEDULE 13G/A  SCYNEXIS INC                           Filed by: FEDERATED HERMES, INC.</title>
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   <title>Form  4          SCYNEXIS INC              For: Jun 26  Filed by: Tinmouth Brian Philippe</title>
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   <title>Form  4          SCYNEXIS INC              For: Jun 26  Filed by: Tinmouth Brian Philippe</title>
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   <title>Form  4          SCYNEXIS INC              For: Jun 26  Filed by: Macdonald Guy</title>
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   <title>Form  4          SCYNEXIS INC              For: Jun 26  Filed by: ANIDO ARMANDO</title>
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   <title>Form  4          SCYNEXIS INC              For: Jun 26  Filed by: HASTINGS DAVID C</title>
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   <title>Form  4          SCYNEXIS INC              For: Jun 26  Filed by: HASTINGS DAVID C</title>
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   <title>Form  4          SCYNEXIS INC              For: Jun 26  Filed by: HANHAM ANN</title>
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   <title>Form  4          SCYNEXIS INC              For: Jun 26  Filed by: HANHAM ANN</title>
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   <title>Scynexis starts Phase 1 trial of SCY-770 for rare kidney disease</title>
   <link>http://www.streetinsider.com/FDA/Scynexis+starts+Phase+1+trial+of+SCY-770+for+rare+kidney+disease/26709946.html</link>
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&lt;p&gt;Scynexis (NASDAQ: SCYX) announced the initiation of a Phase 1 clinical study of SCY-770, an AMP-activated protein kinase (AMPK) activator being developed for Autosomal Dominant Polycystic Kidney Disease (ADPKD), according to a company press release.&lt;/p&gt;

&lt;p&gt;The study will enroll healthy participants in a sequential design. An initial cohort will receive a single 500 mg dose of SCY-770 under fed and fasted conditions to assess food effect and pharmacokinetics. Subsequent cohorts will evaluate SCY-770 at 750 mg once daily or 500 mg twice daily, compared with placebo, over seven days. Topline data are expected in the third quarter of 2026.&lt;/p&gt;

&lt;p&gt;Results from the</description>
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   <title>Scynexis starts Phase 1 trial of SCY-770 for rare kidney disease</title>
   <link>http://www.streetinsider.com/FDA/Scynexis+starts+Phase+1+trial+of+SCY-770+for+rare+kidney+disease/26709946.html</link>
   <description>

&lt;p&gt;Scynexis (NASDAQ: SCYX) announced the initiation of a Phase 1 clinical study of SCY-770, an AMP-activated protein kinase (AMPK) activator being developed for Autosomal Dominant Polycystic Kidney Disease (ADPKD), according to a company press release.&lt;/p&gt;

&lt;p&gt;The study will enroll healthy participants in a sequential design. An initial cohort will receive a single 500 mg dose of SCY-770 under fed and fasted conditions to assess food effect and pharmacokinetics. Subsequent cohorts will evaluate SCY-770 at 750 mg once daily or 500 mg twice daily, compared with placebo, over seven days. Topline data are expected in the third quarter of 2026.&lt;/p&gt;

&lt;p&gt;Results from the</description>
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   <title>Scynexis starts Phase 1 trial of SCY-770 for rare kidney disease</title>
   <link>http://www.streetinsider.com/FDA/Scynexis+starts+Phase+1+trial+of+SCY-770+for+rare+kidney+disease/26709946.html</link>
   <description>

&lt;p&gt;Scynexis (NASDAQ: SCYX) announced the initiation of a Phase 1 clinical study of SCY-770, an AMP-activated protein kinase (AMPK) activator being developed for Autosomal Dominant Polycystic Kidney Disease (ADPKD), according to a company press release.&lt;/p&gt;

&lt;p&gt;The study will enroll healthy participants in a sequential design. An initial cohort will receive a single 500 mg dose of SCY-770 under fed and fasted conditions to assess food effect and pharmacokinetics. Subsequent cohorts will evaluate SCY-770 at 750 mg once daily or 500 mg twice daily, compared with placebo, over seven days. Topline data are expected in the third quarter of 2026.&lt;/p&gt;

&lt;p&gt;Results from the</description>
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   <title>Scynexis starts Phase 1 trial of SCY-770 for rare kidney disease</title>
   <link>http://www.streetinsider.com/FDA/Scynexis+starts+Phase+1+trial+of+SCY-770+for+rare+kidney+disease/26709946.html</link>
   <description>

&lt;p&gt;Scynexis (NASDAQ: SCYX) announced the initiation of a Phase 1 clinical study of SCY-770, an AMP-activated protein kinase (AMPK) activator being developed for Autosomal Dominant Polycystic Kidney Disease (ADPKD), according to a company press release.&lt;/p&gt;

&lt;p&gt;The study will enroll healthy participants in a sequential design. An initial cohort will receive a single 500 mg dose of SCY-770 under fed and fasted conditions to assess food effect and pharmacokinetics. Subsequent cohorts will evaluate SCY-770 at 750 mg once daily or 500 mg twice daily, compared with placebo, over seven days. Topline data are expected in the third quarter of 2026.&lt;/p&gt;

&lt;p&gt;Results from the</description>
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   <title>SCYNEXIS Initiates Phase 1 Study of SCY-770, a Novel AMPK Activator for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)</title>
   <link>http://www.streetinsider.com/Press+Releases/SCYNEXIS+Initiates+Phase+1+Study+of+SCY-770%2C+a+Novel+AMPK+Activator+for+the+Treatment+of+Autosomal+Dominant+Polycystic+Kidney+Disease+%28ADPKD%29/26709867.html</link>
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&lt;p align=&quot;justify&quot;&gt;JERSEY CITY, N.J., June  30, 2026  (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IFK1nZRax3UOBdvSPkdzeq9fQDuV27jOI6ntMNsYneSy7xoURMvcLQ0_y9fxO3CKBE1Io1pdsmiodRs7gJcw0UR4C2X91_u13z8_F790ElYgpiBvwT8pYZB40CoqRKx4&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;SCYX&lt;/a&gt;), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator. The study will characterize the food-effect and define the pharmacokinetics of two dosing regimens for SCY-770 to support dose selection for the Phase 2 study in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), on track for Q4 2026.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;“Initiating this Phase 1 study of SCY-770 marks an</description>
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   <title>SCYNEXIS Initiates Phase 1 Study of SCY-770, a Novel AMPK Activator for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)</title>
   <link>http://www.streetinsider.com/Press+Releases/SCYNEXIS+Initiates+Phase+1+Study+of+SCY-770%2C+a+Novel+AMPK+Activator+for+the+Treatment+of+Autosomal+Dominant+Polycystic+Kidney+Disease+%28ADPKD%29/26709867.html</link>
   <description>
&lt;p align=&quot;justify&quot;&gt;JERSEY CITY, N.J., June  30, 2026  (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IFK1nZRax3UOBdvSPkdzeq9fQDuV27jOI6ntMNsYneSy7xoURMvcLQ0_y9fxO3CKBE1Io1pdsmiodRs7gJcw0UR4C2X91_u13z8_F790ElYgpiBvwT8pYZB40CoqRKx4&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;SCYX&lt;/a&gt;), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator. The study will characterize the food-effect and define the pharmacokinetics of two dosing regimens for SCY-770 to support dose selection for the Phase 2 study in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), on track for Q4 2026.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;“Initiating this Phase 1 study of SCY-770 marks an</description>
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   <title>SCYNEXIS Initiates Phase 1 Study of SCY-770, a Novel AMPK Activator for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)</title>
   <link>http://www.streetinsider.com/Press+Releases/SCYNEXIS+Initiates+Phase+1+Study+of+SCY-770%2C+a+Novel+AMPK+Activator+for+the+Treatment+of+Autosomal+Dominant+Polycystic+Kidney+Disease+%28ADPKD%29/26709867.html</link>
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&lt;p align=&quot;justify&quot;&gt;JERSEY CITY, N.J., June  30, 2026  (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IFK1nZRax3UOBdvSPkdzeq9fQDuV27jOI6ntMNsYneSy7xoURMvcLQ0_y9fxO3CKBE1Io1pdsmiodRs7gJcw0UR4C2X91_u13z8_F790ElYgpiBvwT8pYZB40CoqRKx4&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;SCYX&lt;/a&gt;), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator. The study will characterize the food-effect and define the pharmacokinetics of two dosing regimens for SCY-770 to support dose selection for the Phase 2 study in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), on track for Q4 2026.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;“Initiating this Phase 1 study of SCY-770 marks an</description>
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&lt;p align=&quot;justify&quot;&gt;JERSEY CITY, N.J., June  30, 2026  (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IFK1nZRax3UOBdvSPkdzeq9fQDuV27jOI6ntMNsYneSy7xoURMvcLQ0_y9fxO3CKBE1Io1pdsmiodRs7gJcw0UR4C2X91_u13z8_F790ElYgpiBvwT8pYZB40CoqRKx4&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;SCYX&lt;/a&gt;), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator. The study will characterize the food-effect and define the pharmacokinetics of two dosing regimens for SCY-770 to support dose selection for the Phase 2 study in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), on track for Q4 2026.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;“Initiating this Phase 1 study of SCY-770 marks an</description>
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   <title>SCYNEXIS Initiates Phase 1 Study of SCY-770, a Novel AMPK Activator for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)</title>
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&lt;p align=&quot;justify&quot;&gt;JERSEY CITY, N.J., June  30, 2026  (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IFK1nZRax3UOBdvSPkdzeq9fQDuV27jOI6ntMNsYneSy7xoURMvcLQ0_y9fxO3CKBE1Io1pdsmiodRs7gJcw0UR4C2X91_u13z8_F790ElYgpiBvwT8pYZB40CoqRKx4&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;SCYX&lt;/a&gt;), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator. The study will characterize the food-effect and define the pharmacokinetics of two dosing regimens for SCY-770 to support dose selection for the Phase 2 study in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), on track for Q4 2026.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;“Initiating this Phase 1 study of SCY-770 marks an</description>
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   <title>SCYNEXIS Initiates Phase 1 Study of SCY-770, a Novel AMPK Activator for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)</title>
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&lt;p align=&quot;justify&quot;&gt;JERSEY CITY, N.J., June  30, 2026  (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IFK1nZRax3UOBdvSPkdzeq9fQDuV27jOI6ntMNsYneSy7xoURMvcLQ0_y9fxO3CKBE1Io1pdsmiodRs7gJcw0UR4C2X91_u13z8_F790ElYgpiBvwT8pYZB40CoqRKx4&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;SCYX&lt;/a&gt;), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator. The study will characterize the food-effect and define the pharmacokinetics of two dosing regimens for SCY-770 to support dose selection for the Phase 2 study in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), on track for Q4 2026.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;“Initiating this Phase 1 study of SCY-770 marks an</description>
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   <title>SCYNEXIS Initiates Phase 1 Study of SCY-770, a Novel AMPK Activator for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)</title>
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&lt;p align=&quot;justify&quot;&gt;JERSEY CITY, N.J., June  30, 2026  (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IFK1nZRax3UOBdvSPkdzeq9fQDuV27jOI6ntMNsYneSy7xoURMvcLQ0_y9fxO3CKBE1Io1pdsmiodRs7gJcw0UR4C2X91_u13z8_F790ElYgpiBvwT8pYZB40CoqRKx4&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;SCYX&lt;/a&gt;), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator. The study will characterize the food-effect and define the pharmacokinetics of two dosing regimens for SCY-770 to support dose selection for the Phase 2 study in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), on track for Q4 2026.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;“Initiating this Phase 1 study of SCY-770 marks an</description>
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   <title>SCYNEXIS Initiates Phase 1 Study of SCY-770, a Novel AMPK Activator for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)</title>
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&lt;p align=&quot;justify&quot;&gt;JERSEY CITY, N.J., June  30, 2026  (GLOBE NEWSWIRE) -- SCYNEXIS, Inc. (NASDAQ: &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IFK1nZRax3UOBdvSPkdzeq9fQDuV27jOI6ntMNsYneSy7xoURMvcLQ0_y9fxO3CKBE1Io1pdsmiodRs7gJcw0UR4C2X91_u13z8_F790ElYgpiBvwT8pYZB40CoqRKx4&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;SCYX&lt;/a&gt;), a clinical-stage biotechnology company advancing novel therapies for severe rare diseases, today announced initiation of a Phase 1 study of SCY-770, a first-in-class, potent and direct AMP-activated protein kinase (AMPK) activator. The study will characterize the food-effect and define the pharmacokinetics of two dosing regimens for SCY-770 to support dose selection for the Phase 2 study in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), on track for Q4 2026.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;“Initiating this Phase 1 study of SCY-770 marks an</description>
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