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   <title>Rhythm Pharmaceuticals (RYTM) Reiterated at Market Outperform by Citizens </title>
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   <description>&lt;p&gt;Citizens analyst Jonathan Wolleben reiterated a Market Outperform rating and $155.00 price target on Rhythm Pharmaceuticals (NASDAQ: RYTM).&lt;/p&gt;&lt;p&gt;The analyst commented, &quot; We continue to like setmelanotide’s expansion into Prader-Willi Syndrome (PWS), supported by early evidence that MC4R agonism can deliver a differentiated clinical profile— most notably with meaningful BMI reductions, which has not been demonstrated with the only FDA-approved therapy, Vykat XR. While comparisons are limited by small sample size, open-label design, and cross-trial differences, the early hyperphagia signal appears at least comparable to Vykat XR, with the added benefit of weight loss. RYTM shares climbed to &gt;$115 when the</description>
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   <title>Form  DEFA14A    RHYTHM PHARMACEUTICALS,              </title>
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   <title>Rhythm Pharmaceuticals Announces Seven Abstracts Accepted for Presentation at ENDO 2026</title>
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   <description>&lt;p align=&quot;left&quot;&gt;BOSTON, May  29, 2026  (GLOBE NEWSWIRE) --  Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced that seven presentations, including four late-breaking abstracts, have been accepted for presentation at The Endocrine Society’s Annual Meeting (ENDO 2026) taking place June 13-16, 2026 in Chicago.&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;Jennifer Miller, M.D., Pediatric Endocrinology, University of Florida College of Medicine, will present results from an ongoing Phase 2 trial of setmelanotide in patients with Prader-Willi syndrome (PWS), evaluating higher doses and longer treatment duration. The</description>
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   <title>Rhythm Pharmaceuticals Announces Seven Abstracts Accepted for Presentation at ENDO 2026</title>
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   <description>&lt;p align=&quot;left&quot;&gt;BOSTON, May  29, 2026  (GLOBE NEWSWIRE) --  Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced that seven presentations, including four late-breaking abstracts, have been accepted for presentation at The Endocrine Society’s Annual Meeting (ENDO 2026) taking place June 13-16, 2026 in Chicago.&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;Jennifer Miller, M.D., Pediatric Endocrinology, University of Florida College of Medicine, will present results from an ongoing Phase 2 trial of setmelanotide in patients with Prader-Willi syndrome (PWS), evaluating higher doses and longer treatment duration. The</description>
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   <title>Rhythm Pharmaceuticals Announces Publication of New Bardet-Biedl Syndrome Diagnostic Algorithm in the American Journal of Medical Genetics</title>
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   <title>Rhythm Pharmaceuticals Announces Publication of New Bardet-Biedl Syndrome Diagnostic Algorithm in the American Journal of Medical Genetics</title>
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&lt;p align=&quot;left&quot;&gt;BOSTON, May  28, 2026  (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced the publication of a new, evidence-based consensus-driven diagnostic algorithm for Bardet-Biedl syndrome (BBS). “Streamlining Diagnosis of Bardet-Biedl Syndrome: New Diagnostic Algorithm with Updated Criteria,” was published in the peer-reviewed &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=IGVJHOyFHzGz4XDOjIx1OFAY8LepN5Jw2YKqvqtZDzIsBf56LQfNWkXVrwQvtD3Pi5t7XaYV0rwTNlALcisZeDOe7KT6lFSmhUCanWIi-pYToiIgQNJRYK51EsGuYJJCzeCAgpYw_0r0k2XuFiZUQgCg7DuiTXSUOvezDFDh5GY-KCfrZIGj3_qMe3yI4c2LYPa8xLxKjaBJh22XAHS3_w==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;&lt;em&gt;American Journal of Medical Genetics&lt;/em&gt;&lt;/a&gt;.&lt;/p&gt;  &lt;p align=&quot;left&quot;&gt;This simplified and practical diagnostic algorithm for healthcare practitioners is designed to reduce time to an informed diagnosis of BBS. A multidisciplinary group of international experts and</description>
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