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   <title>Rigel to present pralsetinib cancer data at ESMO Congress 2026</title>
   <link>http://www.streetinsider.com/Corporate+News/Rigel+to+present+pralsetinib+cancer+data+at+ESMO+Congress+2026/27201045.html</link>
   <description>&lt;p&gt;Rigel Pharmaceuticals (Nasdaq: RIGL) announced it will present clinical data on its drug GAVRETO (pralsetinib) at the European Society for Medical Oncology (ESMO) Congress in Madrid, Spain, running October 23 to October 27, 2026.&lt;/p&gt;&lt;p&gt;A pooled analysis of 49 patients with RET fusion-positive solid tumors from the ARROW and TAPISTRY clinical trials, excluding non-small cell lung cancer (NSCLC) and thyroid tumors, showed an overall response rate (ORR) of 53% and a median duration of response of 12.2 months. Patients with previously treated pancreatic tumors had an ORR of 88% (7 of 8 patients).&lt;/p&gt;&lt;p&gt;In the TAPISTRY trial cohort of 16 response-evaluable patients</description>
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   <pubDate>Mon, 19 Oct 2026 08:06:55 -0400</pubDate>
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   <title>Rigel Highlights New GAVRETO® (pralsetinib) Data Across RET Fusion-Positive Cancers in Oral and Poster Presentations at ESMO Congress 2026</title>
   <link>http://www.streetinsider.com/Press+Releases/Rigel+Highlights+New+GAVRETO%C2%AE+%28pralsetinib%29+Data+Across+RET+Fusion-Positive+Cancers+in+Oral+and+Poster+Presentations+at+ESMO+Congress+2026/27201032.html</link>
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                &lt;ul type=&quot;disc&quot;&gt;
                  &lt;li&gt;&lt;i&gt;Pooled ARROW and TAPISTRY analysis demonstrated a 53% overall response rate in patients with RET fusion-positive solid tumors&lt;/i&gt;&lt;/li&gt;
                  &lt;li&gt;&lt;i&gt;Additional analyses highlight first-line clinical outcomes and patient-reported quality of life in RET fusion-positive NSCLC and efficacy and safety in RET fusion-positive thyroid cancer&lt;/i&gt;&lt;/li&gt;
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   <pubDate>Mon, 19 Oct 2026 08:05:00 -0400</pubDate>
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   <title>Rigel Highlights New GAVRETO® (pralsetinib) Data Across RET Fusion-Positive Cancers in Oral and Poster Presentations at ESMO Congress 2026</title>
   <link>http://www.streetinsider.com/PRNewswire/Rigel+Highlights+New+GAVRETO%C2%AE+%28pralsetinib%29+Data+Across+RET+Fusion-Positive+Cancers+in+Oral+and+Poster+Presentations+at+ESMO+Congress+2026/27201032.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
                &lt;ul type=&quot;disc&quot;&gt;
                  &lt;li&gt;&lt;i&gt;Pooled ARROW and TAPISTRY analysis demonstrated a 53% overall response rate in patients with RET fusion-positive solid tumors&lt;/i&gt;&lt;/li&gt;
                  &lt;li&gt;&lt;i&gt;Additional analyses highlight first-line clinical outcomes and patient-reported quality of life in RET fusion-positive NSCLC and efficacy and safety in RET fusion-positive thyroid cancer&lt;/i&gt;&lt;/li&gt;
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   <pubDate>Mon, 19 Oct 2026 08:05:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RIGL</category>
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   <title>Rigel Pharmaceuticals, Inc. Announces Inducement Grants under NASDAQ Listing Rule 5635(c)(4)</title>
   <link>http://www.streetinsider.com/Press+Releases/Rigel+Pharmaceuticals%2C+Inc.+Announces+Inducement+Grants+under+NASDAQ+Listing+Rule+5635%28c%29%284%29/27139045.html</link>
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                &lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Oct. 2, 2026&lt;/chron&gt;&lt;/span&gt; /&lt;span&gt;PRNewswire&lt;/span&gt;/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals, Inc.&lt;/span&gt; (&quot;Rigel&quot;) (&lt;span&gt;Nasdaq&lt;/span&gt;: &lt;span&gt;RIGL&lt;/span&gt;) today announced that it has granted awards pursuant to the &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals, Inc.&lt;/span&gt; Inducement Plan, approved by the Compensation Committee of Rigel's Board of Directors and granted as an inducement material to employees entering into employment with Rigel, in accordance with &lt;span&gt;NASDAQ&lt;/span&gt; Listing Rule 5635(c)(4). Specifically, Rigel granted 35,275 restricted stock units to 18 non-executive employees vesting</description>
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   <pubDate>Fri, 02 Oct 2026 08:05:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RIGL</category>
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   <title>Rigel Pharmaceuticals, Inc. Announces Inducement Grants under NASDAQ Listing Rule 5635(c)(4)</title>
   <link>http://www.streetinsider.com/PRNewswire/Rigel+Pharmaceuticals%2C+Inc.+Announces+Inducement+Grants+under+NASDAQ+Listing+Rule+5635%28c%29%284%29/27139045.html</link>
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                &lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Oct. 2, 2026&lt;/chron&gt;&lt;/span&gt; /&lt;span&gt;PRNewswire&lt;/span&gt;/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals, Inc.&lt;/span&gt; (&quot;Rigel&quot;) (&lt;span&gt;Nasdaq&lt;/span&gt;: &lt;span&gt;RIGL&lt;/span&gt;) today announced that it has granted awards pursuant to the &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals, Inc.&lt;/span&gt; Inducement Plan, approved by the Compensation Committee of Rigel's Board of Directors and granted as an inducement material to employees entering into employment with Rigel, in accordance with &lt;span&gt;NASDAQ&lt;/span&gt; Listing Rule 5635(c)(4). Specifically, Rigel granted 35,275 restricted stock units to 18 non-executive employees vesting</description>
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   <pubDate>Fri, 02 Oct 2026 08:05:00 -0400</pubDate>
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   <title>Rigel Pharmaceuticals (RIGL) PT Raised to $49 at Piper Sandler</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Rigel+Pharmaceuticals+%28RIGL%29+PT+Raised+to+%2449+at+Piper+Sandler/26934911.html</link>
   <description>Piper Sandler analyst Allison Bratzel raised the price target on Rigel Pharmaceuticals (NASDAQ: RIGL) to $49.00  (from $40.00) while maintaining a Neutral rating.</description>
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   <pubDate>Mon, 17 Aug 2026 07:43:56 -0400</pubDate>
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   <title>Rigel Pharmaceuticals (RIGL) PT Raised to $85 at H.C. Wainwright</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Rigel+Pharmaceuticals+%28RIGL%29+PT+Raised+to+%2485+at+H.C.+Wainwright/26934555.html</link>
   <description>H.C. Wainwright analyst Joseph Pantginis raised the price target on Rigel Pharmaceuticals (NASDAQ: RIGL) to $85.00  (from $57.00) while maintaining a Buy rating.</description>
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   <pubDate>Mon, 17 Aug 2026 06:45:59 -0400</pubDate>
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   <title>Form  SCHEDULE 13G/A  RIGEL PHARMACEUTICALS                  Filed by: ARMISTICE CAPITAL, LLC</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++SCHEDULE+13GA++RIGEL+PHARMACEUTICALS++++++++++++++++++Filed+by%3A+ARMISTICE+CAPITAL%2C+LLC/26926375.html</link>
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   <pubDate>Fri, 14 Aug 2026 10:25:00 -0400</pubDate>
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   <title>Form  SCHEDULE 13G/A  RIGEL PHARMACEUTICALS                  Filed by: ARMISTICE CAPITAL, LLC</title>
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   <title>Form  SCHEDULE 13G/A  RIGEL PHARMACEUTICALS                  Filed by: Soleus Capital Master Fund, L.P.</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++SCHEDULE+13GA++RIGEL+PHARMACEUTICALS++++++++++++++++++Filed+by%3A+Soleus+Capital+Master+Fund%2C+L.P./26917416.html</link>
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   <pubDate>Thu, 13 Aug 2026 09:00:00 -0400</pubDate>
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   <title>Form  SCHEDULE 13G/A  RIGEL PHARMACEUTICALS                  Filed by: Soleus Capital Master Fund, L.P.</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++SCHEDULE+13GA++RIGEL+PHARMACEUTICALS++++++++++++++++++Filed+by%3A+Soleus+Capital+Master+Fund%2C+L.P./26917416.html</link>
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   <pubDate>Thu, 13 Aug 2026 09:00:00 -0400</pubDate>
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   <title>Rigel launches breast cancer drug Veppanu at $29,400 per month</title>
   <link>http://www.streetinsider.com/Corporate+News/Rigel+launches+breast+cancer+drug+Veppanu+at+%2429%2C400+per+month/26916900.html</link>
   <description>&lt;p&gt;Rigel Pharmaceuticals (NASDAQ: RIGL) announced that Veppanu (vepdegestrant) is now available by prescription in the United States for adults with estrogen receptor-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer whose disease progressed after at least one line of endocrine therapy.&lt;/p&gt;&lt;p&gt;The drug, priced at $29,400 per 30-day supply, is available through specialty distributors and specialty pharmacies in the United States and Puerto Rico. The recommended dose is 200 mg taken orally once daily.&lt;/p&gt;&lt;p&gt;The FDA approved Veppanu in May 2026. The agency describes it as the first approved drug in the PROTAC (PROteolysis TArgeting Chimera) class, which works by degrading disease-causing proteins</description>
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   <pubDate>Thu, 13 Aug 2026 08:05:40 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">RIGL</category>
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   <title>Rigel Announces Availability of VEPPANU™ (vepdegestrant) for Patients with ER+/HER2-, ESR1-Mutated Advanced or Metastatic Breast Cancer</title>
   <link>http://www.streetinsider.com/Press+Releases/Rigel+Announces+Availability+of+VEPPANU%E2%84%A2+%28vepdegestrant%29+for+Patients+with+ER%2BHER2-%2C+ESR1-Mutated+Advanced+or+Metastatic+Breast+Cancer/26916891.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;p class=&quot;prntac&quot;&gt;&lt;i&gt;VEPPANU is the first and only FDA-approved PROTAC and has the potential to become an important new treatment option for adult patients with 2L+ ER+/HER2-, &lt;/i&gt;&lt;i&gt;ESR1-mutated mBC&lt;/i&gt;&lt;/p&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Aug. 11, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals&lt;/span&gt;, Inc. (Nasdaq: RIGL), a commercial stage biotechnology company focused on hematologic disorders and cancer, today announced VEPPANU&lt;sup&gt;TM&lt;/sup&gt; (vepdegestrant) is now available by prescription in &lt;location value=&quot;LC/us&quot; idsrc=&quot;xmltag.org&quot; &gt;the United States&lt;/location&gt; for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (&lt;i&gt;ESR1&lt;/i&gt;)-mutated advanced or metastatic breast cancer (mBC), as detected</description>
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   <pubDate>Thu, 13 Aug 2026 08:05:00 -0400</pubDate>
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   <title>Rigel Announces Availability of VEPPANU™ (vepdegestrant) for Patients with ER+/HER2-, ESR1-Mutated Advanced or Metastatic Breast Cancer</title>
   <link>http://www.streetinsider.com/PRNewswire/Rigel+Announces+Availability+of+VEPPANU%E2%84%A2+%28vepdegestrant%29+for+Patients+with+ER%2BHER2-%2C+ESR1-Mutated+Advanced+or+Metastatic+Breast+Cancer/26916891.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;p class=&quot;prntac&quot;&gt;&lt;i&gt;VEPPANU is the first and only FDA-approved PROTAC and has the potential to become an important new treatment option for adult patients with 2L+ ER+/HER2-, &lt;/i&gt;&lt;i&gt;ESR1-mutated mBC&lt;/i&gt;&lt;/p&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Aug. 11, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals&lt;/span&gt;, Inc. (Nasdaq: RIGL), a commercial stage biotechnology company focused on hematologic disorders and cancer, today announced VEPPANU&lt;sup&gt;TM&lt;/sup&gt; (vepdegestrant) is now available by prescription in &lt;location value=&quot;LC/us&quot; idsrc=&quot;xmltag.org&quot; &gt;the United States&lt;/location&gt; for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (&lt;i&gt;ESR1&lt;/i&gt;)-mutated advanced or metastatic breast cancer (mBC), as detected</description>
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   <title>Rigel Announces Availability of VEPPANU™ (vepdegestrant) for Patients with ER+/HER2-, ESR1-Mutated Advanced or Metastatic Breast Cancer</title>
   <link>http://www.streetinsider.com/Press+Releases/Rigel+Announces+Availability+of+VEPPANU%E2%84%A2+%28vepdegestrant%29+for+Patients+with+ER%2BHER2-%2C+ESR1-Mutated+Advanced+or+Metastatic+Breast+Cancer/26916891.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;p class=&quot;prntac&quot;&gt;&lt;i&gt;VEPPANU is the first and only FDA-approved PROTAC and has the potential to become an important new treatment option for adult patients with 2L+ ER+/HER2-, &lt;/i&gt;&lt;i&gt;ESR1-mutated mBC&lt;/i&gt;&lt;/p&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Aug. 11, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals&lt;/span&gt;, Inc. (Nasdaq: RIGL), a commercial stage biotechnology company focused on hematologic disorders and cancer, today announced VEPPANU&lt;sup&gt;TM&lt;/sup&gt; (vepdegestrant) is now available by prescription in &lt;location value=&quot;LC/us&quot; idsrc=&quot;xmltag.org&quot; &gt;the United States&lt;/location&gt; for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (&lt;i&gt;ESR1&lt;/i&gt;)-mutated advanced or metastatic breast cancer (mBC), as detected</description>
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   <title>Rigel Announces Availability of VEPPANU™ (vepdegestrant) for Patients with ER+/HER2-, ESR1-Mutated Advanced or Metastatic Breast Cancer</title>
   <link>http://www.streetinsider.com/PRNewswire/Rigel+Announces+Availability+of+VEPPANU%E2%84%A2+%28vepdegestrant%29+for+Patients+with+ER%2BHER2-%2C+ESR1-Mutated+Advanced+or+Metastatic+Breast+Cancer/26916891.html</link>
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&lt;p class=&quot;prntac&quot;&gt;&lt;i&gt;VEPPANU is the first and only FDA-approved PROTAC and has the potential to become an important new treatment option for adult patients with 2L+ ER+/HER2-, &lt;/i&gt;&lt;i&gt;ESR1-mutated mBC&lt;/i&gt;&lt;/p&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Aug. 11, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals&lt;/span&gt;, Inc. (Nasdaq: RIGL), a commercial stage biotechnology company focused on hematologic disorders and cancer, today announced VEPPANU&lt;sup&gt;TM&lt;/sup&gt; (vepdegestrant) is now available by prescription in &lt;location value=&quot;LC/us&quot; idsrc=&quot;xmltag.org&quot; &gt;the United States&lt;/location&gt; for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (&lt;i&gt;ESR1&lt;/i&gt;)-mutated advanced or metastatic breast cancer (mBC), as detected</description>
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   <title>Rigel Announces Availability of VEPPANU™ (vepdegestrant) for Patients with ER+/HER2-, ESR1-Mutated Advanced or Metastatic Breast Cancer</title>
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&lt;p class=&quot;prntac&quot;&gt;&lt;i&gt;VEPPANU is the first and only FDA-approved PROTAC and has the potential to become an important new treatment option for adult patients with 2L+ ER+/HER2-, &lt;/i&gt;&lt;i&gt;ESR1-mutated mBC&lt;/i&gt;&lt;/p&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Aug. 11, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals&lt;/span&gt;, Inc. (Nasdaq: RIGL), a commercial stage biotechnology company focused on hematologic disorders and cancer, today announced VEPPANU&lt;sup&gt;TM&lt;/sup&gt; (vepdegestrant) is now available by prescription in &lt;location value=&quot;LC/us&quot; idsrc=&quot;xmltag.org&quot; &gt;the United States&lt;/location&gt; for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (&lt;i&gt;ESR1&lt;/i&gt;)-mutated advanced or metastatic breast cancer (mBC), as detected</description>
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   <title>Rigel Announces Availability of VEPPANU™ (vepdegestrant) for Patients with ER+/HER2-, ESR1-Mutated Advanced or Metastatic Breast Cancer</title>
   <link>http://www.streetinsider.com/PRNewswire/Rigel+Announces+Availability+of+VEPPANU%E2%84%A2+%28vepdegestrant%29+for+Patients+with+ER%2BHER2-%2C+ESR1-Mutated+Advanced+or+Metastatic+Breast+Cancer/26916891.html</link>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;p class=&quot;prntac&quot;&gt;&lt;i&gt;VEPPANU is the first and only FDA-approved PROTAC and has the potential to become an important new treatment option for adult patients with 2L+ ER+/HER2-, &lt;/i&gt;&lt;i&gt;ESR1-mutated mBC&lt;/i&gt;&lt;/p&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Aug. 11, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals&lt;/span&gt;, Inc. (Nasdaq: RIGL), a commercial stage biotechnology company focused on hematologic disorders and cancer, today announced VEPPANU&lt;sup&gt;TM&lt;/sup&gt; (vepdegestrant) is now available by prescription in &lt;location value=&quot;LC/us&quot; idsrc=&quot;xmltag.org&quot; &gt;the United States&lt;/location&gt; for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (&lt;i&gt;ESR1&lt;/i&gt;)-mutated advanced or metastatic breast cancer (mBC), as detected</description>
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   <title>Rigel Announces Availability of VEPPANU™ (vepdegestrant) for Patients with ER+/HER2-, ESR1-Mutated Advanced or Metastatic Breast Cancer</title>
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&lt;div class=&quot;xn-content&quot;&gt;
&lt;p class=&quot;prntac&quot;&gt;&lt;i&gt;VEPPANU is the first and only FDA-approved PROTAC and has the potential to become an important new treatment option for adult patients with 2L+ ER+/HER2-, &lt;/i&gt;&lt;i&gt;ESR1-mutated mBC&lt;/i&gt;&lt;/p&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Aug. 11, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals&lt;/span&gt;, Inc. (Nasdaq: RIGL), a commercial stage biotechnology company focused on hematologic disorders and cancer, today announced VEPPANU&lt;sup&gt;TM&lt;/sup&gt; (vepdegestrant) is now available by prescription in &lt;location value=&quot;LC/us&quot; idsrc=&quot;xmltag.org&quot; &gt;the United States&lt;/location&gt; for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (&lt;i&gt;ESR1&lt;/i&gt;)-mutated advanced or metastatic breast cancer (mBC), as detected</description>
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&lt;p class=&quot;prntac&quot;&gt;&lt;i&gt;VEPPANU is the first and only FDA-approved PROTAC and has the potential to become an important new treatment option for adult patients with 2L+ ER+/HER2-, &lt;/i&gt;&lt;i&gt;ESR1-mutated mBC&lt;/i&gt;&lt;/p&gt;&lt;p&gt;&lt;span class=&quot;legendSpanClass&quot;&gt;&lt;location value=&quot;LU/us.ca.sousco&quot; idsrc=&quot;xmltag.org&quot; &gt;SOUTH SAN FRANCISCO, Calif.&lt;/location&gt;&lt;/span&gt;, &lt;span class=&quot;legendSpanClass&quot;&gt;&lt;chron&gt;Aug. 11, 2026&lt;/chron&gt;&lt;/span&gt; /PRNewswire/ -- &lt;span value=&quot;NASDAQ-NMS:RIGL&quot; idsrc=&quot;xmltag.org&quot; &gt;Rigel Pharmaceuticals&lt;/span&gt;, Inc. (Nasdaq: RIGL), a commercial stage biotechnology company focused on hematologic disorders and cancer, today announced VEPPANU&lt;sup&gt;TM&lt;/sup&gt; (vepdegestrant) is now available by prescription in &lt;location value=&quot;LC/us&quot; idsrc=&quot;xmltag.org&quot; &gt;the United States&lt;/location&gt; for the treatment of adults with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-), estrogen receptor 1 (&lt;i&gt;ESR1&lt;/i&gt;)-mutated advanced or metastatic breast cancer (mBC), as detected</description>
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