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   <title>MediciNova receives patent allowance for glioblastoma combination therapy</title>
   <link>http://www.streetinsider.com/Corporate+News/MediciNova+receives+patent+allowance+for+glioblastoma+combination+therapy/26614461.html</link>
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&lt;p&gt;MediciNova Inc. (NASDAQ: MNOV) received a Notice of Allowance from the U.S. Patent and Trademark Office for a patent application covering the use of ibudilast (MN-166) in combination with anti-PD-1 antibodies for treating glioblastoma, the company announced.&lt;/p&gt;

&lt;p&gt;The patent, expected to expire no earlier than September 2042, covers multiple treatment parameters including dosing regimen, route of administration, and duration of therapy. The allowed claims encompass combinations with multiple anti-PD-1 antibodies across various treatment conditions.&lt;/p&gt;

&lt;p&gt;&quot;This Notice of Allowance further strengthens our intellectual property estate for MN-166 in glioblastoma and supports continued evaluation of ibudilast-based combination strategies in this aggressive malignancy,&quot; said Dr.</description>
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   <pubDate>Mon, 08 Jun 2026 08:00:09 -0400</pubDate>
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   <title>MediciNova Receives Notice of Allowance for New Patent Covering Use of MN-166 in Combination with Anti-PD-1 Immune Checkpoint Inhibitor for Glioblastoma Treatment</title>
   <link>http://www.streetinsider.com/Press+Releases/MediciNova+Receives+Notice+of+Allowance+for+New+Patent+Covering+Use+of+MN-166+in+Combination+with+Anti-PD-1+Immune+Checkpoint+Inhibitor+for+Glioblastoma+Treatment/26614421.html</link>
   <description>&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., June  08, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ:MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for a pending patent application that covers the use of ibudilast (MN-166) in combination with an immune checkpoint inhibitor, specifically an anti-PD-1 antibody, for the treatment of glioblastoma. This patent allowance is expected to further strengthen the intellectual property position supporting the Company’s combination therapy development strategy.&lt;/p&gt;</description>
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   <pubDate>Mon, 08 Jun 2026 08:00:00 -0400</pubDate>
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   <title>MediciNova Receives Notice of Allowance for New Patent Covering Use of MN-166 in Combination with Anti-PD-1 Immune Checkpoint Inhibitor for Glioblastoma Treatment</title>
   <link>http://www.streetinsider.com/Globe+Newswire/MediciNova+Receives+Notice+of+Allowance+for+New+Patent+Covering+Use+of+MN-166+in+Combination+with+Anti-PD-1+Immune+Checkpoint+Inhibitor+for+Glioblastoma+Treatment/26614421.html</link>
   <description>&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., June  08, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ:MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for a pending patent application that covers the use of ibudilast (MN-166) in combination with an immune checkpoint inhibitor, specifically an anti-PD-1 antibody, for the treatment of glioblastoma. This patent allowance is expected to further strengthen the intellectual property position supporting the Company’s combination therapy development strategy.&lt;/p&gt;</description>
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   <title>MediciNova Announces Completion of Last Patient Last Visit in the MN-001-NATG-202 Clinical Trial of MN-001 (Tipelukast)</title>
   <link>http://www.streetinsider.com/Press+Releases/MediciNova+Announces+Completion+of+Last+Patient+Last+Visit+in+the+MN-001-NATG-202+Clinical+Trial+of+MN-001+%28Tipelukast%29/26551785.html</link>
   <description>&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., May  26, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced the completion of last patient last visit (LPLV) in its Phase 2 clinical trial, MN-001-NATG-202, evaluating MN-001 (tipelukast) for the treatment of hypertriglyceridemia and nonalcoholic fatty liver disease (NAFLD) associated with type 2 diabetes mellitus (T2DM).&lt;/p&gt;  &lt;p&gt;The MN-001-NATG-202 study is a multicenter, randomized, double-blind, placebo-controlled trial evaluating MN-001 (tipelukast). Patients were randomized 1:1 to receive either 500 mg/day of MN-001</description>
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   <pubDate>Tue, 26 May 2026 19:00:00 -0400</pubDate>
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   <title>MediciNova Announces Completion of Last Patient Last Visit in the MN-001-NATG-202 Clinical Trial of MN-001 (Tipelukast)</title>
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   <description>&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., May  26, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced the completion of last patient last visit (LPLV) in its Phase 2 clinical trial, MN-001-NATG-202, evaluating MN-001 (tipelukast) for the treatment of hypertriglyceridemia and nonalcoholic fatty liver disease (NAFLD) associated with type 2 diabetes mellitus (T2DM).&lt;/p&gt;  &lt;p&gt;The MN-001-NATG-202 study is a multicenter, randomized, double-blind, placebo-controlled trial evaluating MN-001 (tipelukast). Patients were randomized 1:1 to receive either 500 mg/day of MN-001</description>
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   <pubDate>Tue, 26 May 2026 19:00:00 -0400</pubDate>
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   <title>Form  10-Q       MEDICINOVA INC            For: Mar 31</title>
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   <pubDate>Thu, 14 May 2026 16:16:00 -0400</pubDate>
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   <title>Form  10-Q       MEDICINOVA INC            For: Mar 31</title>
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   <title>Form  ARS        MEDICINOVA INC            For: Dec 31</title>
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   <title>Form  ARS        MEDICINOVA INC            For: Dec 31</title>
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   <title>Form  DEFA14A    MEDICINOVA INC                       </title>
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   <title>Form  DEFA14A    MEDICINOVA INC                       </title>
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   <title>Form  DEF 14A    MEDICINOVA INC            For: Jun 23</title>
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   <title>Form  DEF 14A    MEDICINOVA INC            For: Jun 23</title>
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   <title>New Peer‑Reviewed Study Reveals Actionable Immune–Microenvironment Target in Brain Metastasis; Medicinova Advances Clinical Translation</title>
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&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., April  27, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced that a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) has identified macrophage migration inhibitory factor (MIF)–mediated reprogramming of CD74‑positive microglia and macrophages as a central vulnerability in brain metastasis. The research, recently published in the peer‑reviewed journal “&lt;em&gt;Cancer Research” &lt;/em&gt;(March 2026), demonstrates pharmacological modulation of this pathway using the brain‑penetrant small molecule ibudilast.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The</description>
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   <title>New Peer‑Reviewed Study Reveals Actionable Immune–Microenvironment Target in Brain Metastasis; Medicinova Advances Clinical Translation</title>
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&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., April  27, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced that a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) has identified macrophage migration inhibitory factor (MIF)–mediated reprogramming of CD74‑positive microglia and macrophages as a central vulnerability in brain metastasis. The research, recently published in the peer‑reviewed journal “&lt;em&gt;Cancer Research” &lt;/em&gt;(March 2026), demonstrates pharmacological modulation of this pathway using the brain‑penetrant small molecule ibudilast.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The</description>
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   <title>New Peer‑Reviewed Study Reveals Actionable Immune–Microenvironment Target in Brain Metastasis; Medicinova Advances Clinical Translation</title>
   <link>http://www.streetinsider.com/Press+Releases/New+Peer%E2%80%91Reviewed+Study+Reveals+Actionable+Immune%E2%80%93Microenvironment+Target+in+Brain+Metastasis%3B+Medicinova+Advances+Clinical+Translation/26376349.html</link>
   <description>
&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., April  27, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced that a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) has identified macrophage migration inhibitory factor (MIF)–mediated reprogramming of CD74‑positive microglia and macrophages as a central vulnerability in brain metastasis. The research, recently published in the peer‑reviewed journal “&lt;em&gt;Cancer Research” &lt;/em&gt;(March 2026), demonstrates pharmacological modulation of this pathway using the brain‑penetrant small molecule ibudilast.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The</description>
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   <title>New Peer‑Reviewed Study Reveals Actionable Immune–Microenvironment Target in Brain Metastasis; Medicinova Advances Clinical Translation</title>
   <link>http://www.streetinsider.com/Globe+Newswire/New+Peer%E2%80%91Reviewed+Study+Reveals+Actionable+Immune%E2%80%93Microenvironment+Target+in+Brain+Metastasis%3B+Medicinova+Advances+Clinical+Translation/26376349.html</link>
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&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., April  27, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced that a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) has identified macrophage migration inhibitory factor (MIF)–mediated reprogramming of CD74‑positive microglia and macrophages as a central vulnerability in brain metastasis. The research, recently published in the peer‑reviewed journal “&lt;em&gt;Cancer Research” &lt;/em&gt;(March 2026), demonstrates pharmacological modulation of this pathway using the brain‑penetrant small molecule ibudilast.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The</description>
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   <title>New Peer‑Reviewed Study Reveals Actionable Immune–Microenvironment Target in Brain Metastasis; Medicinova Advances Clinical Translation</title>
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&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., April  27, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced that a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) has identified macrophage migration inhibitory factor (MIF)–mediated reprogramming of CD74‑positive microglia and macrophages as a central vulnerability in brain metastasis. The research, recently published in the peer‑reviewed journal “&lt;em&gt;Cancer Research” &lt;/em&gt;(March 2026), demonstrates pharmacological modulation of this pathway using the brain‑penetrant small molecule ibudilast.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The</description>
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   <title>New Peer‑Reviewed Study Reveals Actionable Immune–Microenvironment Target in Brain Metastasis; Medicinova Advances Clinical Translation</title>
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&lt;p align=&quot;justify&quot;&gt;LA JOLLA, Calif., April  27, 2026  (GLOBE NEWSWIRE) -- MediciNova, Inc., a biopharmaceutical company traded on the NASDAQ Global Market (NASDAQ: MNOV) and the Standard Market of the Tokyo Stock Exchange (Code Number: 4875), today announced that a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) has identified macrophage migration inhibitory factor (MIF)–mediated reprogramming of CD74‑positive microglia and macrophages as a central vulnerability in brain metastasis. The research, recently published in the peer‑reviewed journal “&lt;em&gt;Cancer Research” &lt;/em&gt;(March 2026), demonstrates pharmacological modulation of this pathway using the brain‑penetrant small molecule ibudilast.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;The</description>
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   <pubDate>Mon, 27 Apr 2026 19:00:00 -0400</pubDate>
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   <title>Form  PRER14A    MEDICINOVA INC                       </title>
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   <pubDate>Mon, 20 Apr 2026 17:03:00 -0400</pubDate>
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   <title>Form  PRER14A    MEDICINOVA INC                       </title>
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   <pubDate>Mon, 20 Apr 2026 17:03:00 -0400</pubDate>
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   <title>Form  PRE 14A    MEDICINOVA INC            For: Jun 23</title>
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   <pubDate>Fri, 17 Apr 2026 16:57:00 -0400</pubDate>
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   <title>Form  PRE 14A    MEDICINOVA INC            For: Jun 23</title>
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   <pubDate>Fri, 17 Apr 2026 16:57:00 -0400</pubDate>
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   <title>Maxim Group Resumes MediciNova (MNOV) at Buy, PT $6</title>
   <link>http://www.streetinsider.com/New+Coverage/Maxim+Group+Resumes+MediciNova+%28MNOV%29+at+Buy%2C+PT+%246/26200487.html</link>
   <description>&lt;p&gt;Maxim Group analyst Jason McCarthy resumes coverage on MediciNova (NASDAQ: MNOV) with a Buy rating and a price target of $6.00.&lt;/p&gt;&lt;p&gt;For an analyst ratings summary and ratings history on MediciNova &lt;a href=&quot;http://www.streetinsider.com/rating_history.php?q=MNOV&quot;&gt;click here&lt;/a&gt;. For more ratings news on MediciNova &lt;a href=&quot;http://www.streetinsider.com/stock_lookup_news.php?q=MNOV&amp;amp;type=analyst&quot;&gt;click here&lt;/a&gt;.&lt;/p&gt;&lt;p&gt;Shares of MediciNova closed at $1.56 yesterday.&lt;/p&gt;</description>
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   <pubDate>Mon, 23 Mar 2026 07:27:13 -0400</pubDate>
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   <title>Maxim Group Resumes MediciNova (MNOV) at Buy, PT $6</title>
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   <description>&lt;p&gt;Maxim Group analyst Jason McCarthy resumes coverage on MediciNova (NASDAQ: MNOV) with a Buy rating and a price target of $6.00.&lt;/p&gt;&lt;p&gt;For an analyst ratings summary and ratings history on MediciNova &lt;a href=&quot;http://www.streetinsider.com/rating_history.php?q=MNOV&quot;&gt;click here&lt;/a&gt;. For more ratings news on MediciNova &lt;a href=&quot;http://www.streetinsider.com/stock_lookup_news.php?q=MNOV&amp;amp;type=analyst&quot;&gt;click here&lt;/a&gt;.&lt;/p&gt;&lt;p&gt;Shares of MediciNova closed at $1.56 yesterday.&lt;/p&gt;</description>
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   <pubDate>Mon, 23 Mar 2026 07:27:13 -0400</pubDate>
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