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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
   <link>http://www.streetinsider.com/Press+Releases/MilliporeSigma+Appoints+New+Heads+of+Discovery+Solutions+and+Strategy+%26amp%3B+Business+Development/26614490.html</link>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
   <link>http://www.streetinsider.com/Press+Releases/MilliporeSigma+Appoints+New+Heads+of+Discovery+Solutions+and+Strategy+%26amp%3B+Business+Development/26614490.html</link>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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   <title>MilliporeSigma Appoints New Heads of Discovery Solutions and Strategy &amp;amp; Business Development</title>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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&lt;p&gt;Burlington, Massachusetts, June  08, 2026  (GLOBE NEWSWIRE) --    &lt;/p&gt;  &lt;ul&gt;&lt;li&gt;Clara Sattler de Sousa e Brito appointed Head of Discovery Solutions, bringing extensive international leadership experience across healthcare, medtech and the chemical industry&lt;/li&gt;&lt;li&gt;Robert Machinek appointed Head of Strategy &amp;amp; Business Development, bringing deep expertise in life science strategy, M&amp;amp;A and digital transformation&lt;/li&gt;&lt;li&gt;Appointments strengthen the Life Science leadership team as the business advances its strategy and innovation agenda&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt; &lt;/p&gt;  &lt;p&gt;MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced the appointments of Clara</description>
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&lt;p&gt;Merck KGaA, Darmstadt, Germany, announced that the first patient has been dosed in a Phase 3 clinical trial for precemtabart tocentecan (Precem-TcT), an investigational antibody-drug conjugate for treating metastatic colorectal cancer.&lt;/p&gt;

&lt;p&gt;The PROCEADE-CRC-03 study will evaluate the efficacy and safety of Precem-TcT, administered alone or with bevacizumab, in patients with metastatic colorectal cancer who are intolerant to or have progressed after systemic therapies. The trial will be conducted at approximately 165 sites across 20 countries and aims to recruit about 1,020 patients.&lt;/p&gt;

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&lt;p&gt;Merck KGaA, Darmstadt, Germany, announced that the first patient has been dosed in a Phase 3 clinical trial for precemtabart tocentecan (Precem-TcT), an investigational antibody-drug conjugate for treating metastatic colorectal cancer.&lt;/p&gt;

&lt;p&gt;The PROCEADE-CRC-03 study will evaluate the efficacy and safety of Precem-TcT, administered alone or with bevacizumab, in patients with metastatic colorectal cancer who are intolerant to or have progressed after systemic therapies. The trial will be conducted at approximately 165 sites across 20 countries and aims to recruit about 1,020 patients.&lt;/p&gt;

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&lt;p&gt;Merck KGaA, Darmstadt, Germany, announced that the first patient has been dosed in a Phase 3 clinical trial for precemtabart tocentecan (Precem-TcT), an investigational antibody-drug conjugate for treating metastatic colorectal cancer.&lt;/p&gt;

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   <title>Merck KGaA begins phase 3 trial for colorectal cancer drug</title>
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&lt;p&gt;Merck KGaA, Darmstadt, Germany, announced that the first patient has been dosed in a Phase 3 clinical trial for precemtabart tocentecan (Precem-TcT), an investigational antibody-drug conjugate for treating metastatic colorectal cancer.&lt;/p&gt;

&lt;p&gt;The PROCEADE-CRC-03 study will evaluate the efficacy and safety of Precem-TcT, administered alone or with bevacizumab, in patients with metastatic colorectal cancer who are intolerant to or have progressed after systemic therapies. The trial will be conducted at approximately 165 sites across 20 countries and aims to recruit about 1,020 patients.&lt;/p&gt;

&lt;p&gt;Precem-TcT targets CEACAM5, a protein overexpressed in approximately 90% of colorectal tumors. The drug combines an antibody with exatecan, a</description>
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   <pubDate>Thu, 21 May 2026 08:01:16 -0400</pubDate>
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   <title>Merck KGaA begins phase 3 trial for colorectal cancer drug</title>
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   <description>

&lt;p&gt;Merck KGaA, Darmstadt, Germany, announced that the first patient has been dosed in a Phase 3 clinical trial for precemtabart tocentecan (Precem-TcT), an investigational antibody-drug conjugate for treating metastatic colorectal cancer.&lt;/p&gt;

&lt;p&gt;The PROCEADE-CRC-03 study will evaluate the efficacy and safety of Precem-TcT, administered alone or with bevacizumab, in patients with metastatic colorectal cancer who are intolerant to or have progressed after systemic therapies. The trial will be conducted at approximately 165 sites across 20 countries and aims to recruit about 1,020 patients.&lt;/p&gt;

&lt;p&gt;Precem-TcT targets CEACAM5, a protein overexpressed in approximately 90% of colorectal tumors. The drug combines an antibody with exatecan, a</description>
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   <title>Merck KGaA begins phase 3 trial for colorectal cancer drug</title>
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&lt;p&gt;Merck KGaA, Darmstadt, Germany, announced that the first patient has been dosed in a Phase 3 clinical trial for precemtabart tocentecan (Precem-TcT), an investigational antibody-drug conjugate for treating metastatic colorectal cancer.&lt;/p&gt;

&lt;p&gt;The PROCEADE-CRC-03 study will evaluate the efficacy and safety of Precem-TcT, administered alone or with bevacizumab, in patients with metastatic colorectal cancer who are intolerant to or have progressed after systemic therapies. The trial will be conducted at approximately 165 sites across 20 countries and aims to recruit about 1,020 patients.&lt;/p&gt;

&lt;p&gt;Precem-TcT targets CEACAM5, a protein overexpressed in approximately 90% of colorectal tumors. The drug combines an antibody with exatecan, a</description>
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   <title>Merck KGaA begins phase 3 trial for colorectal cancer drug</title>
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&lt;p&gt;Merck KGaA, Darmstadt, Germany, announced that the first patient has been dosed in a Phase 3 clinical trial for precemtabart tocentecan (Precem-TcT), an investigational antibody-drug conjugate for treating metastatic colorectal cancer.&lt;/p&gt;

&lt;p&gt;The PROCEADE-CRC-03 study will evaluate the efficacy and safety of Precem-TcT, administered alone or with bevacizumab, in patients with metastatic colorectal cancer who are intolerant to or have progressed after systemic therapies. The trial will be conducted at approximately 165 sites across 20 countries and aims to recruit about 1,020 patients.&lt;/p&gt;

&lt;p&gt;Precem-TcT targets CEACAM5, a protein overexpressed in approximately 90% of colorectal tumors. The drug combines an antibody with exatecan, a</description>
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