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   <title>MBX Biosciences to Participate in Upcoming November Investor Conferences</title>
   <link>http://www.streetinsider.com/Press+Releases/MBX+Biosciences+to+Participate+in+Upcoming+November+Investor+Conferences/27177459.html</link>
   <description>
&lt;p&gt;CARMEL, Ind. and BURLINGTON, Mass., Oct.  13, 2026  (GLOBE NEWSWIRE) -- MBX Biosciences, Inc. (Nasdaq: MBX), a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies for the treatment of endocrine and metabolic disorders, today announced that Steve Hoerter, Chairman and Chief Executive Officer, and Sam Azoulay, M.D., Chief Medical Officer, will present at, and participate in, the following upcoming investor conferences:&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;Guggenheim 3rd Annual Healthcare Innovation Conference&lt;/strong&gt;&lt;br/&gt;Date: Tuesday, November 10, 2026&lt;br/&gt;Format: Fireside Chat and 1x1 meetings&lt;br/&gt;Time: 11:00 – 11:25 a.m. EST &lt;br/&gt;Location: Boston, MA&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;UBS Global Biopharma Conference&lt;/strong&gt;&lt;br/&gt;Date: Tuesday,</description>
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   <pubDate>Tue, 13 Oct 2026 08:00:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
   	  </item>
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   <title>MBX Biosciences to Participate in Upcoming November Investor Conferences</title>
   <link>http://www.streetinsider.com/Globe+Newswire/MBX+Biosciences+to+Participate+in+Upcoming+November+Investor+Conferences/27177459.html</link>
   <description>
&lt;p&gt;CARMEL, Ind. and BURLINGTON, Mass., Oct.  13, 2026  (GLOBE NEWSWIRE) -- MBX Biosciences, Inc. (Nasdaq: MBX), a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies for the treatment of endocrine and metabolic disorders, today announced that Steve Hoerter, Chairman and Chief Executive Officer, and Sam Azoulay, M.D., Chief Medical Officer, will present at, and participate in, the following upcoming investor conferences:&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;Guggenheim 3rd Annual Healthcare Innovation Conference&lt;/strong&gt;&lt;br/&gt;Date: Tuesday, November 10, 2026&lt;br/&gt;Format: Fireside Chat and 1x1 meetings&lt;br/&gt;Time: 11:00 – 11:25 a.m. EST &lt;br/&gt;Location: Boston, MA&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;UBS Global Biopharma Conference&lt;/strong&gt;&lt;br/&gt;Date: Tuesday,</description>
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   <pubDate>Tue, 13 Oct 2026 08:00:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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  <item>
   <title>MBX Biosciences Inc (MBX) PT Raised to $84 at Stifel</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/MBX+Biosciences+Inc+%28MBX%29+PT+Raised+to+%2484+at+Stifel/27173405.html</link>
   <description>&lt;p&gt;Stifel analyst Annabel Samimy raised the price target on MBX Biosciences Inc (NASDAQ: MBX) to $84.00 (from $70.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;We reiterate our Buy rating on MBX, raising our TP to $84. MBX is approaching its Part-C readout from the Ph.1 trial of MBX-4291 (monthly GLP-1/GIP) in obesity, following already strong indications from the Part-B portion that showed the intended characteristics of its smooth PK profile—high tolerability with a long half-life that allows for monthly dosing. Part C will be the first unblinded look following a unique, self-titrating regimen that reached -7% blinded weight loss/WL,</description>
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   <pubDate>Mon, 12 Oct 2026 05:15:30 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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  <item>
   <title>MBX Biosciences Inc (MBX) PT Raised to $84 at Stifel</title>
   <link>http://www.streetinsider.com/Analyst+Comments/MBX+Biosciences+Inc+%28MBX%29+PT+Raised+to+%2484+at+Stifel/27173405.html</link>
   <description>&lt;p&gt;Stifel analyst Annabel Samimy raised the price target on MBX Biosciences Inc (NASDAQ: MBX) to $84.00 (from $70.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst comments &quot;We reiterate our Buy rating on MBX, raising our TP to $84. MBX is approaching its Part-C readout from the Ph.1 trial of MBX-4291 (monthly GLP-1/GIP) in obesity, following already strong indications from the Part-B portion that showed the intended characteristics of its smooth PK profile—high tolerability with a long half-life that allows for monthly dosing. Part C will be the first unblinded look following a unique, self-titrating regimen that reached -7% blinded weight loss/WL,</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Analyst+Comments/MBX+Biosciences+Inc+%28MBX%29+PT+Raised+to+%2484+at+Stifel/27173405.html</guid>
   <pubDate>Mon, 12 Oct 2026 05:15:30 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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   <title>Microbix Making Keynote Presentation at Masters Summit 2026</title>
   <link>http://www.streetinsider.com/Press+Releases/Microbix+Making+Keynote+Presentation+at+Masters+Summit+2026/27163448.html</link>
   <description>
      &lt;p&gt;&lt;strong id=&quot;dateline&quot;&gt;MISSISSAUGA, ON / &lt;a href='https://www.accessnewswire.com/'&gt;ACCESS Newswire&lt;/a&gt; / October 8, 2026 / &lt;/strong&gt;Microbix Biosystems Inc. &lt;strong&gt;(TSX:MBX)(OTCQX:MBXBF), Microbix®&lt;/strong&gt;), a life sciences innovator, manufacturer, and exporter, announces that it will be presenting to its life sciences clients and peers at the &lt;i&gt;Masters Summit 2026&lt;/i&gt;, organized by leading eQMS provider MasterControl, Inc. and being hosted at the Hyatt Regency in Salt Lake City, Utah on October 12-15, 2026.&lt;/p&gt;&lt;p&gt;Microbix's Manager of IT, Dmytro Panchenko, and QC Project Lead Semiramida (Nina) Markosyan, will present to 600+ specialist attendees at the &lt;i&gt;Masters Summit 2026&lt;/i&gt; about the Company's successful onboarding and</description>
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   <pubDate>Thu, 08 Oct 2026 07:00:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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   <title>Microbix Making Keynote Presentation at Masters Summit 2026</title>
   <link>http://www.streetinsider.com/ACCESS+Newswire/Microbix+Making+Keynote+Presentation+at+Masters+Summit+2026/27163448.html</link>
   <description>
      &lt;p&gt;&lt;strong id=&quot;dateline&quot;&gt;MISSISSAUGA, ON / &lt;a href='https://www.accessnewswire.com/'&gt;ACCESS Newswire&lt;/a&gt; / October 8, 2026 / &lt;/strong&gt;Microbix Biosystems Inc. &lt;strong&gt;(TSX:MBX)(OTCQX:MBXBF), Microbix®&lt;/strong&gt;), a life sciences innovator, manufacturer, and exporter, announces that it will be presenting to its life sciences clients and peers at the &lt;i&gt;Masters Summit 2026&lt;/i&gt;, organized by leading eQMS provider MasterControl, Inc. and being hosted at the Hyatt Regency in Salt Lake City, Utah on October 12-15, 2026.&lt;/p&gt;&lt;p&gt;Microbix's Manager of IT, Dmytro Panchenko, and QC Project Lead Semiramida (Nina) Markosyan, will present to 600+ specialist attendees at the &lt;i&gt;Masters Summit 2026&lt;/i&gt; about the Company's successful onboarding and</description>
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   <pubDate>Thu, 08 Oct 2026 07:00:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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   <title>MBX Biosciences Inc (MBX) PT Raised to $150 at Guggenheim</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/MBX+Biosciences+Inc+%28MBX%29+PT+Raised+to+%24150+at+Guggenheim/27138706.html</link>
   <description>(Updated - October 2, 2026 6:49 AM EDT)

&lt;p&gt;Guggenheim analyst Seamus Fernandez raised the price target on MBX Biosciences Inc (NASDAQ: MBX) to $150.00 (from $88.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst commented: &quot;We are raising our PT to $150 (from $88 prior) driven by our updated estimates for MBX 4291, potential once monthly GLP/GIP for obesity, following our proprietary obesity survey and our comps analysis ahead of 12-wk obesity data in 4Q26. Our survey of high-volume obesity-treating physicians (n=30; see HERE indicated: (1) the market will continue to expand; (2) GI tolerability is a leading cause of discontinuation and a</description>
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   <pubDate>Fri, 02 Oct 2026 06:49:03 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
   	  </item>
  <item>
   <title>MBX Biosciences Inc (MBX) PT Raised to $150 at Guggenheim</title>
   <link>http://www.streetinsider.com/Analyst+Comments/MBX+Biosciences+Inc+%28MBX%29+PT+Raised+to+%24150+at+Guggenheim/27138706.html</link>
   <description>(Updated - October 2, 2026 6:49 AM EDT)

&lt;p&gt;Guggenheim analyst Seamus Fernandez raised the price target on MBX Biosciences Inc (NASDAQ: MBX) to $150.00 (from $88.00) while maintaining a Buy rating.&lt;/p&gt;&lt;p&gt;The analyst commented: &quot;We are raising our PT to $150 (from $88 prior) driven by our updated estimates for MBX 4291, potential once monthly GLP/GIP for obesity, following our proprietary obesity survey and our comps analysis ahead of 12-wk obesity data in 4Q26. Our survey of high-volume obesity-treating physicians (n=30; see HERE indicated: (1) the market will continue to expand; (2) GI tolerability is a leading cause of discontinuation and a</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Analyst+Comments/MBX+Biosciences+Inc+%28MBX%29+PT+Raised+to+%24150+at+Guggenheim/27138706.html</guid>
   <pubDate>Fri, 02 Oct 2026 06:49:03 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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   <title>UBS Reiterates Buy Rating on MBX Biosciences Inc (MBX), Says Stock Remains Undervalued</title>
   <link>http://www.streetinsider.com/Analyst+Comments/UBS+Reiterates+Buy+Rating+on+MBX+Biosciences+Inc+%28MBX%29%2C+Says+Stock+Remains+Undervalued/27111153.html</link>
   <description>&lt;p&gt;UBS analyst Michael Yee reiterated a Buy rating and $90.00 price target on MBX Biosciences Inc (NASDAQ: MBX).&lt;/p&gt;&lt;p&gt;The analyst commented, &quot;We hosted MBX’s new mgmt team on the road last week and came away more bullish on the stock. The key focus for the stock remains the 12-week obesity readout for the lead long-acting GLP1/GIPR program in Q4. We like the program and believe it could present a compelling profile with competitive weight loss (6-9% at week 12), a potentially cleaner GI tolerability profile, and oncemonthly dosing. Overall, we like the stock, with the weekly PTH program already in Phase</description>
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   <pubDate>Mon, 28 Sep 2026 09:41:47 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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   <title>Microbix Presenting at Muskoka Capital Event </title>
   <link>http://www.streetinsider.com/Press+Releases/Microbix+Presenting+at+Muskoka+Capital+Event+/27093183.html</link>
   <description>
      &lt;p&gt;&lt;strong id=&quot;dateline&quot;&gt;MISSISSAUGA, ON / &lt;a href='https://www.accessnewswire.com/'&gt;ACCESS Newswire&lt;/a&gt; / September 23, 2026 / &lt;/strong&gt;Microbix Biosystems Inc. (&lt;strong&gt;TSX:MBX)(OTCQX:MBXBF)(Microbix&lt;sup&gt;®&lt;/sup&gt;&lt;/strong&gt;), a life sciences innovator, manufacturer, and exporter, announces that it will be presenting to investors at the &lt;i&gt;Muskoka Capital Event&lt;/i&gt;, organized by Capital Event Management Ltd. and being hosted at the JW Marriott Rosseau Muskoka, in Minett, Ontario, September 25 to 27, 2025.&lt;/p&gt;&lt;p&gt;Microbix's CEO, Cameron Groome, and Director of Product Management, Pavel Zhelev, will undertake a series of 18 one-on-one meetings with growth company investors during the formal portion of the event. The presentation slides to which they</description>
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   <pubDate>Wed, 23 Sep 2026 07:00:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
   	  </item>
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   <title>Microbix Presenting at Muskoka Capital Event </title>
   <link>http://www.streetinsider.com/ACCESS+Newswire/Microbix+Presenting+at+Muskoka+Capital+Event+/27093183.html</link>
   <description>
      &lt;p&gt;&lt;strong id=&quot;dateline&quot;&gt;MISSISSAUGA, ON / &lt;a href='https://www.accessnewswire.com/'&gt;ACCESS Newswire&lt;/a&gt; / September 23, 2026 / &lt;/strong&gt;Microbix Biosystems Inc. (&lt;strong&gt;TSX:MBX)(OTCQX:MBXBF)(Microbix&lt;sup&gt;®&lt;/sup&gt;&lt;/strong&gt;), a life sciences innovator, manufacturer, and exporter, announces that it will be presenting to investors at the &lt;i&gt;Muskoka Capital Event&lt;/i&gt;, organized by Capital Event Management Ltd. and being hosted at the JW Marriott Rosseau Muskoka, in Minett, Ontario, September 25 to 27, 2025.&lt;/p&gt;&lt;p&gt;Microbix's CEO, Cameron Groome, and Director of Product Management, Pavel Zhelev, will undertake a series of 18 one-on-one meetings with growth company investors during the formal portion of the event. The presentation slides to which they</description>
   <guid isPermaLink="true">http://www.streetinsider.com/ACCESS+Newswire/Microbix+Presenting+at+Muskoka+Capital+Event+/27093183.html</guid>
   <pubDate>Wed, 23 Sep 2026 07:00:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
   	  </item>
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   <title>Microbix Qualifies as Supplier for Five Major Dx Test-Makers Product Lines for Support of Leading IVD Manufacturers</title>
   <link>http://www.streetinsider.com/Press+Releases/Microbix+Qualifies+as+Supplier+for+Five+Major+Dx+Test-Makers+Product+Lines+for+Support+of+Leading+IVD+Manufacturers/27039123.html</link>
   <description>
      &lt;p&gt;&lt;strong id=&quot;dateline&quot;&gt;MISSISSAUGA, ON / &lt;a href='https://www.accessnewswire.com/'&gt;ACCESS Newswire&lt;/a&gt; / September 9, 2026 / &lt;/strong&gt;Microbix Biosystems Inc. (&lt;strong&gt;TSX:MBX)(OTCQX:MBXBF)(Microbix®&lt;/strong&gt;), a life sciences innovator, manufacturer, and exporter, announces that it has completed formal qualification to become a supplier for five &lt;i&gt;in-vitro&lt;/i&gt; diagnostics (IVD) manufacturers (&quot;&lt;strong&gt;Dx Test-Makers&lt;/strong&gt;&quot;). Each of these five Dx Test-Makers are considered to be one of the ten largest such companies by revenues, and Microbix is pleased to have successfully completed their supplier audit &amp; quality review processes.&lt;/p&gt;&lt;p&gt;Clearing these detailed and multifaceted supplier qualification processes permits Microbix to supply critical products to these Dx Test-makers, across</description>
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   <pubDate>Wed, 09 Sep 2026 07:00:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
   	  </item>
  <item>
   <title>Microbix Qualifies as Supplier for Five Major Dx Test-Makers Product Lines for Support of Leading IVD Manufacturers</title>
   <link>http://www.streetinsider.com/ACCESS+Newswire/Microbix+Qualifies+as+Supplier+for+Five+Major+Dx+Test-Makers+Product+Lines+for+Support+of+Leading+IVD+Manufacturers/27039123.html</link>
   <description>
      &lt;p&gt;&lt;strong id=&quot;dateline&quot;&gt;MISSISSAUGA, ON / &lt;a href='https://www.accessnewswire.com/'&gt;ACCESS Newswire&lt;/a&gt; / September 9, 2026 / &lt;/strong&gt;Microbix Biosystems Inc. (&lt;strong&gt;TSX:MBX)(OTCQX:MBXBF)(Microbix®&lt;/strong&gt;), a life sciences innovator, manufacturer, and exporter, announces that it has completed formal qualification to become a supplier for five &lt;i&gt;in-vitro&lt;/i&gt; diagnostics (IVD) manufacturers (&quot;&lt;strong&gt;Dx Test-Makers&lt;/strong&gt;&quot;). Each of these five Dx Test-Makers are considered to be one of the ten largest such companies by revenues, and Microbix is pleased to have successfully completed their supplier audit &amp; quality review processes.&lt;/p&gt;&lt;p&gt;Clearing these detailed and multifaceted supplier qualification processes permits Microbix to supply critical products to these Dx Test-makers, across</description>
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   <pubDate>Wed, 09 Sep 2026 07:00:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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   <title>Form  8-K        MBX Biosciences, Inc.     For: Aug 27</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++MBX+Biosciences%2C+Inc.+++++For%3A+Aug+27/26985528.html</link>
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   <pubDate>Thu, 27 Aug 2026 08:34:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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   <title>Form  8-K        MBX Biosciences, Inc.     For: Aug 27</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++8-K++++++++MBX+Biosciences%2C+Inc.+++++For%3A+Aug+27/26985528.html</link>
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   <pubDate>Thu, 27 Aug 2026 08:34:00 -0400</pubDate>
      	<category domain="http://rss.financialcontent.com/stocksymbol">MBX</category>
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   <title>MBX Biosciences doses first patient in Phase 3 hypoparathyroidism trial</title>
   <link>http://www.streetinsider.com/FDA/MBX+Biosciences+doses+first+patient+in+Phase+3+hypoparathyroidism+trial/26985091.html</link>
   <description>

&lt;p&gt;MBX Biosciences, Inc. (Nasdaq: MBX) announced that the first patient has been dosed in its pivotal Phase 3 oPTimize clinical trial evaluating once-weekly canvuparatide for the treatment of chronic hypoparathyroidism, according to a company statement dated Aug. 27, 2026.&lt;/p&gt;

&lt;p&gt;The trial (NCT07699471) is a global, multicenter, randomized, double-blind, placebo-controlled study. Approximately 160 adults with chronic hypoparathyroidism will be enrolled and randomized 3:1 to receive canvuparatide or placebo during a 26-week double-blind treatment period, followed by a 78-week open-label extension.&lt;/p&gt;

&lt;p&gt;The 26-week treatment period includes a four-week fixed-dose period at 600 micrograms once weekly, an 18-week individualized dose-titration period of up to 1,600</description>
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   <pubDate>Thu, 27 Aug 2026 08:01:41 -0400</pubDate>
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   <title>MBX Biosciences doses first patient in Phase 3 hypoparathyroidism trial</title>
   <link>http://www.streetinsider.com/FDA/MBX+Biosciences+doses+first+patient+in+Phase+3+hypoparathyroidism+trial/26985091.html</link>
   <description>

&lt;p&gt;MBX Biosciences, Inc. (Nasdaq: MBX) announced that the first patient has been dosed in its pivotal Phase 3 oPTimize clinical trial evaluating once-weekly canvuparatide for the treatment of chronic hypoparathyroidism, according to a company statement dated Aug. 27, 2026.&lt;/p&gt;

&lt;p&gt;The trial (NCT07699471) is a global, multicenter, randomized, double-blind, placebo-controlled study. Approximately 160 adults with chronic hypoparathyroidism will be enrolled and randomized 3:1 to receive canvuparatide or placebo during a 26-week double-blind treatment period, followed by a 78-week open-label extension.&lt;/p&gt;

&lt;p&gt;The 26-week treatment period includes a four-week fixed-dose period at 600 micrograms once weekly, an 18-week individualized dose-titration period of up to 1,600</description>
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   <pubDate>Thu, 27 Aug 2026 08:01:41 -0400</pubDate>
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&lt;p&gt;MBX Biosciences, Inc. (Nasdaq: MBX) announced that the first patient has been dosed in its pivotal Phase 3 oPTimize clinical trial evaluating once-weekly canvuparatide for the treatment of chronic hypoparathyroidism, according to a company statement dated Aug. 27, 2026.&lt;/p&gt;

&lt;p&gt;The trial (NCT07699471) is a global, multicenter, randomized, double-blind, placebo-controlled study. Approximately 160 adults with chronic hypoparathyroidism will be enrolled and randomized 3:1 to receive canvuparatide or placebo during a 26-week double-blind treatment period, followed by a 78-week open-label extension.&lt;/p&gt;

&lt;p&gt;The 26-week treatment period includes a four-week fixed-dose period at 600 micrograms once weekly, an 18-week individualized dose-titration period of up to 1,600</description>
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   <title>MBX Biosciences doses first patient in Phase 3 hypoparathyroidism trial</title>
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&lt;p&gt;MBX Biosciences, Inc. (Nasdaq: MBX) announced that the first patient has been dosed in its pivotal Phase 3 oPTimize clinical trial evaluating once-weekly canvuparatide for the treatment of chronic hypoparathyroidism, according to a company statement dated Aug. 27, 2026.&lt;/p&gt;

&lt;p&gt;The trial (NCT07699471) is a global, multicenter, randomized, double-blind, placebo-controlled study. Approximately 160 adults with chronic hypoparathyroidism will be enrolled and randomized 3:1 to receive canvuparatide or placebo during a 26-week double-blind treatment period, followed by a 78-week open-label extension.&lt;/p&gt;

&lt;p&gt;The 26-week treatment period includes a four-week fixed-dose period at 600 micrograms once weekly, an 18-week individualized dose-titration period of up to 1,600</description>
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   <title>MBX Biosciences doses first patient in Phase 3 hypoparathyroidism trial</title>
   <link>http://www.streetinsider.com/FDA/MBX+Biosciences+doses+first+patient+in+Phase+3+hypoparathyroidism+trial/26985091.html</link>
   <description>

&lt;p&gt;MBX Biosciences, Inc. (Nasdaq: MBX) announced that the first patient has been dosed in its pivotal Phase 3 oPTimize clinical trial evaluating once-weekly canvuparatide for the treatment of chronic hypoparathyroidism, according to a company statement dated Aug. 27, 2026.&lt;/p&gt;

&lt;p&gt;The trial (NCT07699471) is a global, multicenter, randomized, double-blind, placebo-controlled study. Approximately 160 adults with chronic hypoparathyroidism will be enrolled and randomized 3:1 to receive canvuparatide or placebo during a 26-week double-blind treatment period, followed by a 78-week open-label extension.&lt;/p&gt;

&lt;p&gt;The 26-week treatment period includes a four-week fixed-dose period at 600 micrograms once weekly, an 18-week individualized dose-titration period of up to 1,600</description>
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   <title>MBX Biosciences doses first patient in Phase 3 hypoparathyroidism trial</title>
   <link>http://www.streetinsider.com/FDA/MBX+Biosciences+doses+first+patient+in+Phase+3+hypoparathyroidism+trial/26985091.html</link>
   <description>

&lt;p&gt;MBX Biosciences, Inc. (Nasdaq: MBX) announced that the first patient has been dosed in its pivotal Phase 3 oPTimize clinical trial evaluating once-weekly canvuparatide for the treatment of chronic hypoparathyroidism, according to a company statement dated Aug. 27, 2026.&lt;/p&gt;

&lt;p&gt;The trial (NCT07699471) is a global, multicenter, randomized, double-blind, placebo-controlled study. Approximately 160 adults with chronic hypoparathyroidism will be enrolled and randomized 3:1 to receive canvuparatide or placebo during a 26-week double-blind treatment period, followed by a 78-week open-label extension.&lt;/p&gt;

&lt;p&gt;The 26-week treatment period includes a four-week fixed-dose period at 600 micrograms once weekly, an 18-week individualized dose-titration period of up to 1,600</description>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Pivotal Phase 3 oPTimize trial design builds on positive Phase 2 Avail™ results and durable &lt;br/&gt;one-year clinical benefit&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Global registrational trial to enroll approximately 160 adults with HP to support once-weekly &lt;br/&gt;canvuparatide’s potential as a best-in-class PTH replacement therapy&lt;/em&gt;&lt;/p&gt;  &lt;p&gt;CARMEL, Ind., and BURLINGTON, Mass., Aug.  27, 2026  (GLOBE NEWSWIRE) -- MBX Biosciences, Inc. (Nasdaq: MBX), a clinical-stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders, today announced that the first patient has been dosed in its pivotal Phase 3 oPTimize clinical</description>
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   <title>MBX Biosciences Announces First Patient Dosed in Pivotal Phase 3 oPTimize Trial of Once-Weekly Canvuparatide in Adults with Hypoparathyroidism</title>
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&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Pivotal Phase 3 oPTimize trial design builds on positive Phase 2 Avail™ results and durable &lt;br/&gt;one-year clinical benefit&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Global registrational trial to enroll approximately 160 adults with HP to support once-weekly &lt;br/&gt;canvuparatide’s potential as a best-in-class PTH replacement therapy&lt;/em&gt;&lt;/p&gt;  &lt;p&gt;CARMEL, Ind., and BURLINGTON, Mass., Aug.  27, 2026  (GLOBE NEWSWIRE) -- MBX Biosciences, Inc. (Nasdaq: MBX), a clinical-stage biopharmaceutical company focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders, today announced that the first patient has been dosed in its pivotal Phase 3 oPTimize clinical</description>
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   <title>MBX Biosciences Announces First Patient Dosed in Pivotal Phase 3 oPTimize Trial of Once-Weekly Canvuparatide in Adults with Hypoparathyroidism</title>
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