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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: Swain Judith L</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: Swain Judith L</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: Sullivan Diane E.</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: Sullivan Diane E.</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: SOBECKI CHRISTOPHER J</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: SOBECKI CHRISTOPHER J</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: BARKER SAM L</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: Cheung Ivan</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: Amouyal Philippe</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: Amouyal Philippe</title>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: DEBBANE RAYMOND</title>
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   <pubDate>Thu, 04 Jun 2026 16:10:00 -0400</pubDate>
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   <title>Form  4          LEXICON PHARMACEUTICALS,  For: Jun 03  Filed by: DEBBANE RAYMOND</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++LEXICON+PHARMACEUTICALS%2C++For%3A+Jun+03++Filed+by%3A+DEBBANE+RAYMOND/26605739.html</link>
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   <title>Lexicon to Present Data at the American Diabetes Association (ADA) 2026 Scientific Sessions</title>
   <link>http://www.streetinsider.com/Press+Releases/Lexicon+to+Present+Data+at+the+American+Diabetes+Association+%28ADA%29+2026+Scientific+Sessions/26595531.html</link>
   <description>&lt;p&gt;&lt;strong&gt;Presentations highlight consistent A1c reductions with sotagliflozin in type 1 diabetes and pharmacokinetics of pilavapadin across renal function groups&lt;/strong&gt;&lt;/p&gt;&lt;p&gt;THE WOODLANDS, Texas, June  03, 2026  (GLOBE NEWSWIRE) -- &lt;a href=&quot;https://www.globenewswire.com/Tracker?data=ByDsgmuwUDsqkm7lyyWmKYGHd7wtKH5nBDEE-7IaJB3T0CqcuKdt_bL65AAuf70gHmwZtXe79zT4HTc83_DPXHKi6BRoAKXTR4dOdgdvuWAiZzpsC3fjoOAJQdXhzh00&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;&lt;u&gt;Lexicon Pharmaceuticals, Inc.&lt;/u&gt;&lt;/a&gt; (Nasdaq: LXRX) today announced that it will present data from clinical studies of sotagliflozin in Type 1 diabetes (T1D) and pilavapadin in diabetic peripheral neuropathic pain (DPNP) at the American Diabetes Association (ADA) 2026 Scientific Sessions, being held June 5-8 in New Orleans, Louisiana.&lt;/p&gt;  &lt;p&gt;“We look forward to engaging with the diabetes community at ADA 2026, as well as sharing additional data from clinical studies</description>
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   <pubDate>Wed, 03 Jun 2026 08:00:00 -0400</pubDate>
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   <title>Lexicon to Present Data at the American Diabetes Association (ADA) 2026 Scientific Sessions</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Lexicon+to+Present+Data+at+the+American+Diabetes+Association+%28ADA%29+2026+Scientific+Sessions/26595531.html</link>
   <description>&lt;p&gt;&lt;strong&gt;Presentations highlight consistent A1c reductions with sotagliflozin in type 1 diabetes and pharmacokinetics of pilavapadin across renal function groups&lt;/strong&gt;&lt;/p&gt;&lt;p&gt;THE WOODLANDS, Texas, June  03, 2026  (GLOBE NEWSWIRE) -- &lt;a href=&quot;https://www.globenewswire.com/Tracker?data=ByDsgmuwUDsqkm7lyyWmKYGHd7wtKH5nBDEE-7IaJB3T0CqcuKdt_bL65AAuf70gHmwZtXe79zT4HTc83_DPXHKi6BRoAKXTR4dOdgdvuWAiZzpsC3fjoOAJQdXhzh00&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;&lt;u&gt;Lexicon Pharmaceuticals, Inc.&lt;/u&gt;&lt;/a&gt; (Nasdaq: LXRX) today announced that it will present data from clinical studies of sotagliflozin in Type 1 diabetes (T1D) and pilavapadin in diabetic peripheral neuropathic pain (DPNP) at the American Diabetes Association (ADA) 2026 Scientific Sessions, being held June 5-8 in New Orleans, Louisiana.&lt;/p&gt;  &lt;p&gt;“We look forward to engaging with the diabetes community at ADA 2026, as well as sharing additional data from clinical studies</description>
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   <pubDate>Wed, 03 Jun 2026 08:00:00 -0400</pubDate>
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   <title>Lexicon Pharmaceuticals to Present at the 2026 Jefferies Global Healthcare Conference</title>
   <link>http://www.streetinsider.com/Press+Releases/Lexicon+Pharmaceuticals+to+Present+at+the+2026+Jefferies+Global+Healthcare+Conference/26561658.html</link>
   <description>&lt;p align=&quot;left&quot;&gt;THE WOODLANDS, Texas, May  28, 2026  (GLOBE NEWSWIRE) -- &lt;a href=&quot;https://www.globenewswire.com/Tracker?data=Jg-AJURJmAVl73VhxWU7Kgpw_WTIQdGtHGnYgKDyV_aIigVUkXhhNvBbTTV6QOfDm1VY_KoUJeAvJbhTP-amCi2FHQ0frXMP4ryLW4BogG3x_ywbXwSRNxpieF84UibZgkS82s1Zbpoz4bUwD7JJp4pN6kpTSKSM5clwftPi4jh3NjcCUF4JwtuTmPCV10VePDQn5UqQcjIYUoYTFtIrLOP6k_4XWEE5ELecdRWyjoDNBt2naEbuC0DkcUPTMpuXtP8HM4lYdy1oluXvbg5evj-7kkGzDg2BoOjdaNL9CLSWoiOk_vAR6vGcuUmi8wYu&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Lexicon Pharmaceuticals, Inc.&lt;/a&gt; (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 2026 Jefferies Global Healthcare Conference on June 4, 2026 at 2:00 p.m. ET in New York City.&lt;/p&gt;  &lt;p&gt;The live event and a replay of the presentation can be accessed via the Events page of the Company’s website at &lt;a href=&quot;https://www.globenewswire.com/Tracker?data=Gtck0BHXbtVNT6Lf248-Dk1INXsYkc3s-31FNxVFcSdnr2nsXQBBNb2ROhRVyTt1sUsBfXYYefSkpDmenp1035-d49m3Lrcc-27vCBbj4MNiLjgwriUHFO2K4xk0VACgRfnTpofEHx758NKPS2LobL6lnSwF-L-tGCZOJJKD3QBQk_evnAymJ-ThmkzP5LwD2Y_FEcYTuNuYvmfMst83jj61rwRsro6cRWFn2_R1RECAmBO4Fi4QTrF5cZ--Dh3FGfb-6Ig3lzTVk26jOcuBr0nFeVgIVi7eqCakvvQgpW70t3vkKIsYMXj3e3yvbfhM&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;https://investors.lexpharma.com/&lt;/a&gt;.&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;About Lexicon Pharmaceuticals    &lt;/strong&gt;&lt;br /&gt;Lexicon is a biopharmaceutical company with a mission of pioneering medicines that transform patients’ lives. Lexicon has a pipeline of drug candidates</description>
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   <pubDate>Thu, 28 May 2026 08:30:00 -0400</pubDate>
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   <title>Lexicon Pharmaceuticals to Present at the 2026 Jefferies Global Healthcare Conference</title>
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   <description>&lt;p align=&quot;left&quot;&gt;THE WOODLANDS, Texas, May  28, 2026  (GLOBE NEWSWIRE) -- &lt;a href=&quot;https://www.globenewswire.com/Tracker?data=Jg-AJURJmAVl73VhxWU7Kgpw_WTIQdGtHGnYgKDyV_aIigVUkXhhNvBbTTV6QOfDm1VY_KoUJeAvJbhTP-amCi2FHQ0frXMP4ryLW4BogG3x_ywbXwSRNxpieF84UibZgkS82s1Zbpoz4bUwD7JJp4pN6kpTSKSM5clwftPi4jh3NjcCUF4JwtuTmPCV10VePDQn5UqQcjIYUoYTFtIrLOP6k_4XWEE5ELecdRWyjoDNBt2naEbuC0DkcUPTMpuXtP8HM4lYdy1oluXvbg5evj-7kkGzDg2BoOjdaNL9CLSWoiOk_vAR6vGcuUmi8wYu&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Lexicon Pharmaceuticals, Inc.&lt;/a&gt; (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 2026 Jefferies Global Healthcare Conference on June 4, 2026 at 2:00 p.m. ET in New York City.&lt;/p&gt;  &lt;p&gt;The live event and a replay of the presentation can be accessed via the Events page of the Company’s website at &lt;a href=&quot;https://www.globenewswire.com/Tracker?data=Gtck0BHXbtVNT6Lf248-Dk1INXsYkc3s-31FNxVFcSdnr2nsXQBBNb2ROhRVyTt1sUsBfXYYefSkpDmenp1035-d49m3Lrcc-27vCBbj4MNiLjgwriUHFO2K4xk0VACgRfnTpofEHx758NKPS2LobL6lnSwF-L-tGCZOJJKD3QBQk_evnAymJ-ThmkzP5LwD2Y_FEcYTuNuYvmfMst83jj61rwRsro6cRWFn2_R1RECAmBO4Fi4QTrF5cZ--Dh3FGfb-6Ig3lzTVk26jOcuBr0nFeVgIVi7eqCakvvQgpW70t3vkKIsYMXj3e3yvbfhM&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;https://investors.lexpharma.com/&lt;/a&gt;.&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;About Lexicon Pharmaceuticals    &lt;/strong&gt;&lt;br /&gt;Lexicon is a biopharmaceutical company with a mission of pioneering medicines that transform patients’ lives. Lexicon has a pipeline of drug candidates</description>
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   <pubDate>Thu, 28 May 2026 08:30:00 -0400</pubDate>
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   <title>Lexicon Pharmaceuticals to Present at the 4th Annual H.C. Wainwright BioConnect Investor Conference</title>
   <link>http://www.streetinsider.com/Press+Releases/Lexicon+Pharmaceuticals+to+Present+at+the+4th+Annual+H.C.+Wainwright+BioConnect+Investor+Conference/26473667.html</link>
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&lt;p&gt;THE WOODLANDS, Texas, May  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=cRPo06ZRg7ltKf_ATlEwt_4mz-1tKPh-F5qlYGVpW65AvMpEsXseCy9haP_B0UsIE9ZWTVmUFiy_JL3ID6dawhastUyZK1sF5LOvbrMzOZQHiCBr1-2Zm-Ioy2ZSFgDJmZXLNsJSLJDu27kX7Mb931mRvx5Yxe4Z7GwBM94v9kPh0LpOiLWO48s_EDZFs7ROWTnJHGfTO9VebXj3eHCkdmi8lx1Bv0xpcYQUN0q6Fbe_nDEvARYCebiqOS0pxnFSguE2DhelqEJCOIpq3ZfPKZAkEt48kbAjYiy_aRBwmGhV4BWR7N8CiAbTggmcFPRa&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Lexicon Pharmaceuticals, Inc.&lt;/a&gt; (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 4th Annual H.C. Wainwright BioConnect Investor Conference, taking place at the Nasdaq World Headquarters in New York City, on May 19, 2026.&lt;/p&gt;  &lt;p&gt;The live event and a replay of the presentation can be accessed via the Events page of the Company’s website at &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=cFpjOT1CEe_02b0GKwd7plwoYxEZAACnjZraMgVt0dJDSBRqaOzPYOpC7RlnjfbI1cYgkUYbDN4NYNgjnZ_XcraVoxdm4nPeU96oBP5sNLqtuAZtm9crfRL65wTL1MQMjwlyvbwL-ET6aAOHtBBnxWULiWw7Ax6Vn8lTd9KM-fC5TBKD3-64mzyIhQ9M8pa9s4HN6wAOIgMEL5rU8_DAsW7YS0NvDVBqAy_37_ktc3AAGZxMYYokR_9qvgrH3MTM7O5HwMnVuy5jYyaXdzSK-pQAXeE6necfFJEz4klCAfh99ZCRukT9SUHBT8vsujU2&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;https://investors.lexpharma.com/&lt;/a&gt;.&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;About Lexicon Pharmaceuticals  &lt;/strong&gt; &lt;br/&gt;Lexicon is a biopharmaceutical company with a mission of pioneering medicines that transform patients’ lives. Lexicon has</description>
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   <pubDate>Tue, 12 May 2026 08:30:00 -0400</pubDate>
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   <title>Lexicon Pharmaceuticals to Present at the 4th Annual H.C. Wainwright BioConnect Investor Conference</title>
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&lt;p&gt;THE WOODLANDS, Texas, May  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=cRPo06ZRg7ltKf_ATlEwt_4mz-1tKPh-F5qlYGVpW65AvMpEsXseCy9haP_B0UsIE9ZWTVmUFiy_JL3ID6dawhastUyZK1sF5LOvbrMzOZQHiCBr1-2Zm-Ioy2ZSFgDJmZXLNsJSLJDu27kX7Mb931mRvx5Yxe4Z7GwBM94v9kPh0LpOiLWO48s_EDZFs7ROWTnJHGfTO9VebXj3eHCkdmi8lx1Bv0xpcYQUN0q6Fbe_nDEvARYCebiqOS0pxnFSguE2DhelqEJCOIpq3ZfPKZAkEt48kbAjYiy_aRBwmGhV4BWR7N8CiAbTggmcFPRa&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Lexicon Pharmaceuticals, Inc.&lt;/a&gt; (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 4th Annual H.C. Wainwright BioConnect Investor Conference, taking place at the Nasdaq World Headquarters in New York City, on May 19, 2026.&lt;/p&gt;  &lt;p&gt;The live event and a replay of the presentation can be accessed via the Events page of the Company’s website at &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=cFpjOT1CEe_02b0GKwd7plwoYxEZAACnjZraMgVt0dJDSBRqaOzPYOpC7RlnjfbI1cYgkUYbDN4NYNgjnZ_XcraVoxdm4nPeU96oBP5sNLqtuAZtm9crfRL65wTL1MQMjwlyvbwL-ET6aAOHtBBnxWULiWw7Ax6Vn8lTd9KM-fC5TBKD3-64mzyIhQ9M8pa9s4HN6wAOIgMEL5rU8_DAsW7YS0NvDVBqAy_37_ktc3AAGZxMYYokR_9qvgrH3MTM7O5HwMnVuy5jYyaXdzSK-pQAXeE6necfFJEz4klCAfh99ZCRukT9SUHBT8vsujU2&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;https://investors.lexpharma.com/&lt;/a&gt;.&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;About Lexicon Pharmaceuticals  &lt;/strong&gt; &lt;br/&gt;Lexicon is a biopharmaceutical company with a mission of pioneering medicines that transform patients’ lives. Lexicon has</description>
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   <pubDate>Tue, 12 May 2026 08:30:00 -0400</pubDate>
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   <title>Lexicon Pharmaceuticals to Present at the 4th Annual H.C. Wainwright BioConnect Investor Conference</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Lexicon+Pharmaceuticals+to+Present+at+the+4th+Annual+H.C.+Wainwright+BioConnect+Investor+Conference/26473667.html</link>
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&lt;p&gt;THE WOODLANDS, Texas, May  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=cRPo06ZRg7ltKf_ATlEwt_4mz-1tKPh-F5qlYGVpW65AvMpEsXseCy9haP_B0UsIE9ZWTVmUFiy_JL3ID6dawhastUyZK1sF5LOvbrMzOZQHiCBr1-2Zm-Ioy2ZSFgDJmZXLNsJSLJDu27kX7Mb931mRvx5Yxe4Z7GwBM94v9kPh0LpOiLWO48s_EDZFs7ROWTnJHGfTO9VebXj3eHCkdmi8lx1Bv0xpcYQUN0q6Fbe_nDEvARYCebiqOS0pxnFSguE2DhelqEJCOIpq3ZfPKZAkEt48kbAjYiy_aRBwmGhV4BWR7N8CiAbTggmcFPRa&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Lexicon Pharmaceuticals, Inc.&lt;/a&gt; (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 4th Annual H.C. Wainwright BioConnect Investor Conference, taking place at the Nasdaq World Headquarters in New York City, on May 19, 2026.&lt;/p&gt;  &lt;p&gt;The live event and a replay of the presentation can be accessed via the Events page of the Company’s website at &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=cFpjOT1CEe_02b0GKwd7plwoYxEZAACnjZraMgVt0dJDSBRqaOzPYOpC7RlnjfbI1cYgkUYbDN4NYNgjnZ_XcraVoxdm4nPeU96oBP5sNLqtuAZtm9crfRL65wTL1MQMjwlyvbwL-ET6aAOHtBBnxWULiWw7Ax6Vn8lTd9KM-fC5TBKD3-64mzyIhQ9M8pa9s4HN6wAOIgMEL5rU8_DAsW7YS0NvDVBqAy_37_ktc3AAGZxMYYokR_9qvgrH3MTM7O5HwMnVuy5jYyaXdzSK-pQAXeE6necfFJEz4klCAfh99ZCRukT9SUHBT8vsujU2&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;https://investors.lexpharma.com/&lt;/a&gt;.&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;About Lexicon Pharmaceuticals  &lt;/strong&gt; &lt;br/&gt;Lexicon is a biopharmaceutical company with a mission of pioneering medicines that transform patients’ lives. Lexicon has</description>
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   <pubDate>Tue, 12 May 2026 08:30:00 -0400</pubDate>
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   <title>Lexicon Pharmaceuticals to Present at the 4th Annual H.C. Wainwright BioConnect Investor Conference</title>
   <link>http://www.streetinsider.com/Globe+Newswire/Lexicon+Pharmaceuticals+to+Present+at+the+4th+Annual+H.C.+Wainwright+BioConnect+Investor+Conference/26473667.html</link>
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&lt;p&gt;THE WOODLANDS, Texas, May  12, 2026  (GLOBE NEWSWIRE) -- &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=cRPo06ZRg7ltKf_ATlEwt_4mz-1tKPh-F5qlYGVpW65AvMpEsXseCy9haP_B0UsIE9ZWTVmUFiy_JL3ID6dawhastUyZK1sF5LOvbrMzOZQHiCBr1-2Zm-Ioy2ZSFgDJmZXLNsJSLJDu27kX7Mb931mRvx5Yxe4Z7GwBM94v9kPh0LpOiLWO48s_EDZFs7ROWTnJHGfTO9VebXj3eHCkdmi8lx1Bv0xpcYQUN0q6Fbe_nDEvARYCebiqOS0pxnFSguE2DhelqEJCOIpq3ZfPKZAkEt48kbAjYiy_aRBwmGhV4BWR7N8CiAbTggmcFPRa&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;Lexicon Pharmaceuticals, Inc.&lt;/a&gt; (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 4th Annual H.C. Wainwright BioConnect Investor Conference, taking place at the Nasdaq World Headquarters in New York City, on May 19, 2026.&lt;/p&gt;  &lt;p&gt;The live event and a replay of the presentation can be accessed via the Events page of the Company’s website at &lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=cFpjOT1CEe_02b0GKwd7plwoYxEZAACnjZraMgVt0dJDSBRqaOzPYOpC7RlnjfbI1cYgkUYbDN4NYNgjnZ_XcraVoxdm4nPeU96oBP5sNLqtuAZtm9crfRL65wTL1MQMjwlyvbwL-ET6aAOHtBBnxWULiWw7Ax6Vn8lTd9KM-fC5TBKD3-64mzyIhQ9M8pa9s4HN6wAOIgMEL5rU8_DAsW7YS0NvDVBqAy_37_ktc3AAGZxMYYokR_9qvgrH3MTM7O5HwMnVuy5jYyaXdzSK-pQAXeE6necfFJEz4klCAfh99ZCRukT9SUHBT8vsujU2&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;https://investors.lexpharma.com/&lt;/a&gt;.&lt;/p&gt;  &lt;p&gt;&lt;strong&gt;About Lexicon Pharmaceuticals  &lt;/strong&gt; &lt;br/&gt;Lexicon is a biopharmaceutical company with a mission of pioneering medicines that transform patients’ lives. Lexicon has</description>
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   <pubDate>Tue, 12 May 2026 08:30:00 -0400</pubDate>
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   <title>Lexicon Pharmaceuticals (LXRX) PT Raised to $3.10 at Citi</title>
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   <description>Citi analyst Yigal Nochomovitz raised the price target on Lexicon Pharmaceuticals (NASDAQ: LXRX) to $3.10  (from $2.30) while maintaining a Neutral rating.</description>
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   <pubDate>Mon, 11 May 2026 04:35:46 -0400</pubDate>
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