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   <title>XORTX Announces Director Resignation</title>
   <link>http://www.streetinsider.com/Press+Releases/XORTX+Announces+Director+Resignation/26851518.html</link>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  31, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that Anthony Giovinazzo is stepping down from the board of directors for personal reasons and to pursue other interests.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Dr. Allen Davidoff, co-CEO of XORTX, stated, “XORTX management and the board of directors extends our heartfelt appreciation for Mr. Giovinazzo’s efforts as chairman of the board during the past several years. Anthony’s contribution to</description>
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   <pubDate>Fri, 31 Jul 2026 17:00:00 -0400</pubDate>
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   <title>XORTX Announces Director Resignation</title>
   <link>http://www.streetinsider.com/Press+Releases/XORTX+Announces+Director+Resignation/26851518.html</link>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  31, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that Anthony Giovinazzo is stepping down from the board of directors for personal reasons and to pursue other interests.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Dr. Allen Davidoff, co-CEO of XORTX, stated, “XORTX management and the board of directors extends our heartfelt appreciation for Mr. Giovinazzo’s efforts as chairman of the board during the past several years. Anthony’s contribution to</description>
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   <pubDate>Fri, 31 Jul 2026 17:00:00 -0400</pubDate>
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   <title>XORTX Announces Director Resignation</title>
   <link>http://www.streetinsider.com/Press+Releases/XORTX+Announces+Director+Resignation/26851518.html</link>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  31, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that Anthony Giovinazzo is stepping down from the board of directors for personal reasons and to pursue other interests.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Dr. Allen Davidoff, co-CEO of XORTX, stated, “XORTX management and the board of directors extends our heartfelt appreciation for Mr. Giovinazzo’s efforts as chairman of the board during the past several years. Anthony’s contribution to</description>
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   <pubDate>Fri, 31 Jul 2026 17:00:00 -0400</pubDate>
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   <title>XORTX Announces Director Resignation</title>
   <link>http://www.streetinsider.com/Press+Releases/XORTX+Announces+Director+Resignation/26851518.html</link>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  31, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that Anthony Giovinazzo is stepping down from the board of directors for personal reasons and to pursue other interests.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Dr. Allen Davidoff, co-CEO of XORTX, stated, “XORTX management and the board of directors extends our heartfelt appreciation for Mr. Giovinazzo’s efforts as chairman of the board during the past several years. Anthony’s contribution to</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Press+Releases/XORTX+Announces+Director+Resignation/26851518.html</guid>
   <pubDate>Fri, 31 Jul 2026 17:00:00 -0400</pubDate>
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   <title>XORTX Announces Director Resignation</title>
   <link>http://www.streetinsider.com/Globe+Newswire/XORTX+Announces+Director+Resignation/26851518.html</link>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  31, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that Anthony Giovinazzo is stepping down from the board of directors for personal reasons and to pursue other interests.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Dr. Allen Davidoff, co-CEO of XORTX, stated, “XORTX management and the board of directors extends our heartfelt appreciation for Mr. Giovinazzo’s efforts as chairman of the board during the past several years. Anthony’s contribution to</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Globe+Newswire/XORTX+Announces+Director+Resignation/26851518.html</guid>
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   <title>XORTX Announces Director Resignation</title>
   <link>http://www.streetinsider.com/Globe+Newswire/XORTX+Announces+Director+Resignation/26851518.html</link>
   <description>
&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  31, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that Anthony Giovinazzo is stepping down from the board of directors for personal reasons and to pursue other interests.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Dr. Allen Davidoff, co-CEO of XORTX, stated, “XORTX management and the board of directors extends our heartfelt appreciation for Mr. Giovinazzo’s efforts as chairman of the board during the past several years. Anthony’s contribution to</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Globe+Newswire/XORTX+Announces+Director+Resignation/26851518.html</guid>
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   <title>XORTX Announces Director Resignation</title>
   <link>http://www.streetinsider.com/Globe+Newswire/XORTX+Announces+Director+Resignation/26851518.html</link>
   <description>
&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  31, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that Anthony Giovinazzo is stepping down from the board of directors for personal reasons and to pursue other interests.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Dr. Allen Davidoff, co-CEO of XORTX, stated, “XORTX management and the board of directors extends our heartfelt appreciation for Mr. Giovinazzo’s efforts as chairman of the board during the past several years. Anthony’s contribution to</description>
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   <title>XORTX Announces Director Resignation</title>
   <link>http://www.streetinsider.com/Globe+Newswire/XORTX+Announces+Director+Resignation/26851518.html</link>
   <description>
&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  31, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, announces that Anthony Giovinazzo is stepping down from the board of directors for personal reasons and to pursue other interests.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Dr. Allen Davidoff, co-CEO of XORTX, stated, “XORTX management and the board of directors extends our heartfelt appreciation for Mr. Giovinazzo’s efforts as chairman of the board during the past several years. Anthony’s contribution to</description>
   <guid isPermaLink="true">http://www.streetinsider.com/Globe+Newswire/XORTX+Announces+Director+Resignation/26851518.html</guid>
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   <title>XORTX Therapeutics adds Depesh Narotam to its board</title>
   <link>http://www.streetinsider.com/Board+Changes/XORTX+Therapeutics+adds+Depesh+Narotam+to+its+board/26830314.html</link>
   <description>

&lt;p&gt;XORTX Therapeutics Inc. (NASDAQ: XRTX | TSXV: XRTX) announced the appointment of Depesh Narotam to its board of directors as an independent director, effective July 27, 2026.&lt;/p&gt;

&lt;p&gt;Narotam, 43, has also been appointed to serve on the company's Compensation, Governance and Nominating Committee. The board determined that he qualifies as an independent director under applicable Nasdaq listing standards and Canadian securities laws.&lt;/p&gt;

&lt;p&gt;Narotam has worked in financial services for more than 20 years, with a focus on debt financing and mortgage lending. Since December 2020, he has served as a Mortgage Development Manager at Vancity, a British Columbia-based credit union. Prior to</description>
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   <title>XORTX Therapeutics adds Depesh Narotam to its board</title>
   <link>http://www.streetinsider.com/Board+Changes/XORTX+Therapeutics+adds+Depesh+Narotam+to+its+board/26830314.html</link>
   <description>

&lt;p&gt;XORTX Therapeutics Inc. (NASDAQ: XRTX | TSXV: XRTX) announced the appointment of Depesh Narotam to its board of directors as an independent director, effective July 27, 2026.&lt;/p&gt;

&lt;p&gt;Narotam, 43, has also been appointed to serve on the company's Compensation, Governance and Nominating Committee. The board determined that he qualifies as an independent director under applicable Nasdaq listing standards and Canadian securities laws.&lt;/p&gt;

&lt;p&gt;Narotam has worked in financial services for more than 20 years, with a focus on debt financing and mortgage lending. Since December 2020, he has served as a Mortgage Development Manager at Vancity, a British Columbia-based credit union. Prior to</description>
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   <title>XORTX Therapeutics adds Depesh Narotam to its board</title>
   <link>http://www.streetinsider.com/Board+Changes/XORTX+Therapeutics+adds+Depesh+Narotam+to+its+board/26830314.html</link>
   <description>

&lt;p&gt;XORTX Therapeutics Inc. (NASDAQ: XRTX | TSXV: XRTX) announced the appointment of Depesh Narotam to its board of directors as an independent director, effective July 27, 2026.&lt;/p&gt;

&lt;p&gt;Narotam, 43, has also been appointed to serve on the company's Compensation, Governance and Nominating Committee. The board determined that he qualifies as an independent director under applicable Nasdaq listing standards and Canadian securities laws.&lt;/p&gt;

&lt;p&gt;Narotam has worked in financial services for more than 20 years, with a focus on debt financing and mortgage lending. Since December 2020, he has served as a Mortgage Development Manager at Vancity, a British Columbia-based credit union. Prior to</description>
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   <title>XORTX Therapeutics adds Depesh Narotam to its board</title>
   <link>http://www.streetinsider.com/Board+Changes/XORTX+Therapeutics+adds+Depesh+Narotam+to+its+board/26830314.html</link>
   <description>

&lt;p&gt;XORTX Therapeutics Inc. (NASDAQ: XRTX | TSXV: XRTX) announced the appointment of Depesh Narotam to its board of directors as an independent director, effective July 27, 2026.&lt;/p&gt;

&lt;p&gt;Narotam, 43, has also been appointed to serve on the company's Compensation, Governance and Nominating Committee. The board determined that he qualifies as an independent director under applicable Nasdaq listing standards and Canadian securities laws.&lt;/p&gt;

&lt;p&gt;Narotam has worked in financial services for more than 20 years, with a focus on debt financing and mortgage lending. Since December 2020, he has served as a Mortgage Development Manager at Vancity, a British Columbia-based credit union. Prior to</description>
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   <title>XORTX Therapeutics adds Depesh Narotam to its board</title>
   <link>http://www.streetinsider.com/Board+Changes/XORTX+Therapeutics+adds+Depesh+Narotam+to+its+board/26830314.html</link>
   <description>

&lt;p&gt;XORTX Therapeutics Inc. (NASDAQ: XRTX | TSXV: XRTX) announced the appointment of Depesh Narotam to its board of directors as an independent director, effective July 27, 2026.&lt;/p&gt;

&lt;p&gt;Narotam, 43, has also been appointed to serve on the company's Compensation, Governance and Nominating Committee. The board determined that he qualifies as an independent director under applicable Nasdaq listing standards and Canadian securities laws.&lt;/p&gt;

&lt;p&gt;Narotam has worked in financial services for more than 20 years, with a focus on debt financing and mortgage lending. Since December 2020, he has served as a Mortgage Development Manager at Vancity, a British Columbia-based credit union. Prior to</description>
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   <title>XORTX Therapeutics adds Depesh Narotam to its board</title>
   <link>http://www.streetinsider.com/Board+Changes/XORTX+Therapeutics+adds+Depesh+Narotam+to+its+board/26830314.html</link>
   <description>

&lt;p&gt;XORTX Therapeutics Inc. (NASDAQ: XRTX | TSXV: XRTX) announced the appointment of Depesh Narotam to its board of directors as an independent director, effective July 27, 2026.&lt;/p&gt;

&lt;p&gt;Narotam, 43, has also been appointed to serve on the company's Compensation, Governance and Nominating Committee. The board determined that he qualifies as an independent director under applicable Nasdaq listing standards and Canadian securities laws.&lt;/p&gt;

&lt;p&gt;Narotam has worked in financial services for more than 20 years, with a focus on debt financing and mortgage lending. Since December 2020, he has served as a Mortgage Development Manager at Vancity, a British Columbia-based credit union. Prior to</description>
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   <title>XORTX Therapeutics adds Depesh Narotam to its board</title>
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&lt;p&gt;XORTX Therapeutics Inc. (NASDAQ: XRTX | TSXV: XRTX) announced the appointment of Depesh Narotam to its board of directors as an independent director, effective July 27, 2026.&lt;/p&gt;

&lt;p&gt;Narotam, 43, has also been appointed to serve on the company's Compensation, Governance and Nominating Committee. The board determined that he qualifies as an independent director under applicable Nasdaq listing standards and Canadian securities laws.&lt;/p&gt;

&lt;p&gt;Narotam has worked in financial services for more than 20 years, with a focus on debt financing and mortgage lending. Since December 2020, he has served as a Mortgage Development Manager at Vancity, a British Columbia-based credit union. Prior to</description>
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   <pubDate>Wed, 29 Jul 2026 07:00:29 -0400</pubDate>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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&lt;p align=&quot;justify&quot;&gt;CALGARY, Alberta, July  29, 2026  (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. (&amp;quot;&lt;strong&gt;XORTX&lt;/strong&gt;&amp;quot; or the “&lt;strong&gt;Company&lt;/strong&gt;”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.&lt;/p&gt;  &lt;p align=&quot;justify&quot;&gt;Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh</description>
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