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   <title>Form  4          AGIOS PHARMACEUTICALS,    For: Jul 08  Filed by: Backstrom Jay T.</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++AGIOS+PHARMACEUTICALS%2C++++For%3A+Jul+08++Filed+by%3A+Backstrom+Jay+T./26757538.html</link>
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   <pubDate>Fri, 10 Jul 2026 16:18:00 -0400</pubDate>
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   <title>Form  4          AGIOS PHARMACEUTICALS,    For: Jul 08  Filed by: Backstrom Jay T.</title>
   <link>http://www.streetinsider.com/SEC+Filings/Form++4++++++++++AGIOS+PHARMACEUTICALS%2C++++For%3A+Jul+08++Filed+by%3A+Backstrom+Jay+T./26757538.html</link>
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   <pubDate>Fri, 10 Jul 2026 16:18:00 -0400</pubDate>
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   <title>Agios Pharma (AGIO) PT Raised to $32 at RBC Capital</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Agios+Pharma+%28AGIO%29+PT+Raised+to+%2432+at+RBC+Capital/26738633.html</link>
   <description>RBC Capital analyst Luca Issi raised the price target on Agios Pharma (NASDAQ: AGIO) to $32.00  (from $28.00) while maintaining a Sector Perform rating.</description>
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   <pubDate>Tue, 07 Jul 2026 07:55:47 -0400</pubDate>
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   <title>Agios Pharma (AGIO) PT Raised to $41 at Truist Securities</title>
   <link>http://www.streetinsider.com/Analyst+PT+Change/Agios+Pharma+%28AGIO%29+PT+Raised+to+%2441+at+Truist+Securities/26738269.html</link>
   <description>Truist Securities analyst Greg Renza raised the price target on Agios Pharma (NASDAQ: AGIO) to $41.00  (from $36.00) while maintaining a Buy rating.</description>
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   <title>FDA grants priority review to Agios' mitapivat for sickle cell disease</title>
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&lt;p&gt;Agios Pharmaceuticals (Nasdaq: AGIO) announced that the U.S. Food and Drug Administration has accepted its supplemental New Drug Application (sNDA) for mitapivat in sickle cell disease, granting it Priority Review. The FDA's PDUFA goal date is November 1, 2026.&lt;/p&gt;

&lt;p&gt;The sNDA was submitted under the FDA's accelerated approval pathway. Priority Review designation shortens the standard review timeline from 10 months to six months and is granted to applications for medicines that may offer significant improvements in safety or efficacy for serious conditions.&lt;/p&gt;

&lt;p&gt;The application is based on data from the RISE UP Phase 2 and Phase 3 trials, which were global, randomized,</description>
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   <title>FDA grants priority review to Agios' mitapivat for sickle cell disease</title>
   <link>http://www.streetinsider.com/FDA/FDA+grants+priority+review+to+Agios%27+mitapivat+for+sickle+cell+disease/26738203.html</link>
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&lt;p&gt;Agios Pharmaceuticals (Nasdaq: AGIO) announced that the U.S. Food and Drug Administration has accepted its supplemental New Drug Application (sNDA) for mitapivat in sickle cell disease, granting it Priority Review. The FDA's PDUFA goal date is November 1, 2026.&lt;/p&gt;

&lt;p&gt;The sNDA was submitted under the FDA's accelerated approval pathway. Priority Review designation shortens the standard review timeline from 10 months to six months and is granted to applications for medicines that may offer significant improvements in safety or efficacy for serious conditions.&lt;/p&gt;

&lt;p&gt;The application is based on data from the RISE UP Phase 2 and Phase 3 trials, which were global, randomized,</description>
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   <title>FDA grants priority review to Agios' mitapivat for sickle cell disease</title>
   <link>http://www.streetinsider.com/FDA/FDA+grants+priority+review+to+Agios%27+mitapivat+for+sickle+cell+disease/26738203.html</link>
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&lt;p&gt;Agios Pharmaceuticals (Nasdaq: AGIO) announced that the U.S. Food and Drug Administration has accepted its supplemental New Drug Application (sNDA) for mitapivat in sickle cell disease, granting it Priority Review. The FDA's PDUFA goal date is November 1, 2026.&lt;/p&gt;

&lt;p&gt;The sNDA was submitted under the FDA's accelerated approval pathway. Priority Review designation shortens the standard review timeline from 10 months to six months and is granted to applications for medicines that may offer significant improvements in safety or efficacy for serious conditions.&lt;/p&gt;

&lt;p&gt;The application is based on data from the RISE UP Phase 2 and Phase 3 trials, which were global, randomized,</description>
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   <title>FDA grants priority review to Agios' mitapivat for sickle cell disease</title>
   <link>http://www.streetinsider.com/FDA/FDA+grants+priority+review+to+Agios%27+mitapivat+for+sickle+cell+disease/26738203.html</link>
   <description>

&lt;p&gt;Agios Pharmaceuticals (Nasdaq: AGIO) announced that the U.S. Food and Drug Administration has accepted its supplemental New Drug Application (sNDA) for mitapivat in sickle cell disease, granting it Priority Review. The FDA's PDUFA goal date is November 1, 2026.&lt;/p&gt;

&lt;p&gt;The sNDA was submitted under the FDA's accelerated approval pathway. Priority Review designation shortens the standard review timeline from 10 months to six months and is granted to applications for medicines that may offer significant improvements in safety or efficacy for serious conditions.&lt;/p&gt;

&lt;p&gt;The application is based on data from the RISE UP Phase 2 and Phase 3 trials, which were global, randomized,</description>
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   <title>U.S. FDA Grants Priority Review to Agios’ sNDA for Mitapivat in Sickle Cell Disease</title>
   <link>http://www.streetinsider.com/Press+Releases/U.S.+FDA+Grants+Priority+Review+to+Agios%E2%80%99+sNDA+for+Mitapivat+in+Sickle+Cell+Disease/26738195.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;FDA’s PDUFA goal date is November 1, 2026&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;li&gt;If approved, mitapivat is positioned to become the first oral PK activator for patients with sickle cell disease&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., July  07, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for mitapivat, an oral pyruvate kinase (PK) activator, in sickle cell disease with a Priority Review. The Prescription Drug User Fee Act (PDUFA) goal date for</description>
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   <title>U.S. FDA Grants Priority Review to Agios’ sNDA for Mitapivat in Sickle Cell Disease</title>
   <link>http://www.streetinsider.com/Press+Releases/U.S.+FDA+Grants+Priority+Review+to+Agios%E2%80%99+sNDA+for+Mitapivat+in+Sickle+Cell+Disease/26738195.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;FDA’s PDUFA goal date is November 1, 2026&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;li&gt;If approved, mitapivat is positioned to become the first oral PK activator for patients with sickle cell disease&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., July  07, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for mitapivat, an oral pyruvate kinase (PK) activator, in sickle cell disease with a Priority Review. The Prescription Drug User Fee Act (PDUFA) goal date for</description>
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   <title>U.S. FDA Grants Priority Review to Agios’ sNDA for Mitapivat in Sickle Cell Disease</title>
   <link>http://www.streetinsider.com/Press+Releases/U.S.+FDA+Grants+Priority+Review+to+Agios%E2%80%99+sNDA+for+Mitapivat+in+Sickle+Cell+Disease/26738195.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;FDA’s PDUFA goal date is November 1, 2026&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;li&gt;If approved, mitapivat is positioned to become the first oral PK activator for patients with sickle cell disease&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., July  07, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for mitapivat, an oral pyruvate kinase (PK) activator, in sickle cell disease with a Priority Review. The Prescription Drug User Fee Act (PDUFA) goal date for</description>
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   <title>U.S. FDA Grants Priority Review to Agios’ sNDA for Mitapivat in Sickle Cell Disease</title>
   <link>http://www.streetinsider.com/Press+Releases/U.S.+FDA+Grants+Priority+Review+to+Agios%E2%80%99+sNDA+for+Mitapivat+in+Sickle+Cell+Disease/26738195.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;FDA’s PDUFA goal date is November 1, 2026&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;li&gt;If approved, mitapivat is positioned to become the first oral PK activator for patients with sickle cell disease&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., July  07, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for mitapivat, an oral pyruvate kinase (PK) activator, in sickle cell disease with a Priority Review. The Prescription Drug User Fee Act (PDUFA) goal date for</description>
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   <title>U.S. FDA Grants Priority Review to Agios’ sNDA for Mitapivat in Sickle Cell Disease</title>
   <link>http://www.streetinsider.com/Globe+Newswire/U.S.+FDA+Grants+Priority+Review+to+Agios%E2%80%99+sNDA+for+Mitapivat+in+Sickle+Cell+Disease/26738195.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;FDA’s PDUFA goal date is November 1, 2026&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;li&gt;If approved, mitapivat is positioned to become the first oral PK activator for patients with sickle cell disease&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., July  07, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for mitapivat, an oral pyruvate kinase (PK) activator, in sickle cell disease with a Priority Review. The Prescription Drug User Fee Act (PDUFA) goal date for</description>
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   <title>U.S. FDA Grants Priority Review to Agios’ sNDA for Mitapivat in Sickle Cell Disease</title>
   <link>http://www.streetinsider.com/Globe+Newswire/U.S.+FDA+Grants+Priority+Review+to+Agios%E2%80%99+sNDA+for+Mitapivat+in+Sickle+Cell+Disease/26738195.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;FDA’s PDUFA goal date is November 1, 2026&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;li&gt;If approved, mitapivat is positioned to become the first oral PK activator for patients with sickle cell disease&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., July  07, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for mitapivat, an oral pyruvate kinase (PK) activator, in sickle cell disease with a Priority Review. The Prescription Drug User Fee Act (PDUFA) goal date for</description>
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   <title>U.S. FDA Grants Priority Review to Agios’ sNDA for Mitapivat in Sickle Cell Disease</title>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;FDA’s PDUFA goal date is November 1, 2026&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;li&gt;If approved, mitapivat is positioned to become the first oral PK activator for patients with sickle cell disease&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., July  07, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for mitapivat, an oral pyruvate kinase (PK) activator, in sickle cell disease with a Priority Review. The Prescription Drug User Fee Act (PDUFA) goal date for</description>
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   <title>U.S. FDA Grants Priority Review to Agios’ sNDA for Mitapivat in Sickle Cell Disease</title>
   <link>http://www.streetinsider.com/Globe+Newswire/U.S.+FDA+Grants+Priority+Review+to+Agios%E2%80%99+sNDA+for+Mitapivat+in+Sickle+Cell+Disease/26738195.html</link>
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&lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;FDA’s PDUFA goal date is November 1, 2026&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;li&gt;If approved, mitapivat is positioned to become the first oral PK activator for patients with sickle cell disease&lt;br/&gt;&lt;br/&gt;&lt;/li&gt;&lt;/ul&gt;  &lt;p&gt;CAMBRIDGE, Mass., July  07, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted its supplemental New Drug Application (sNDA) for mitapivat, an oral pyruvate kinase (PK) activator, in sickle cell disease with a Priority Review. The Prescription Drug User Fee Act (PDUFA) goal date for</description>
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   <pubDate>Tue, 07 Jul 2026 07:00:00 -0400</pubDate>
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   <title>Agios Pharma (AGIO) PT Raised to $46 at BofA Securities</title>
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   <description>BofA Securities analyst Alec W. Stranahan raised the price target on Agios Pharma (NASDAQ: AGIO) to $46.00  (from $40.00) while maintaining a Buy rating.</description>
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   <pubDate>Tue, 07 Jul 2026 05:16:26 -0400</pubDate>
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   <title>Form  SCHEDULE 13G  AGIOS PHARMACEUTICALS,                 Filed by: D. E. SHAW &amp;amp; CO, L.P.</title>
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   <title>Form  4          AGIOS PHARMACEUTICALS,    For: Jul 01  Filed by: Gheuens Sarah</title>
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   <title>Form  4          AGIOS PHARMACEUTICALS,    For: Jul 01  Filed by: Gheuens Sarah</title>
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   <pubDate>Thu, 02 Jul 2026 16:03:00 -0400</pubDate>
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   <title>Form  144        AGIOS PHARMACEUTICALS,                 Filed by: Gheuens Sarah</title>
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   <title>Form  144        AGIOS PHARMACEUTICALS,                 Filed by: Gheuens Sarah</title>
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   <title>Agios to Host Second Quarter 2026 Financial Results Conference Call and Webcast on July 30 at 8:00 a.m. ET</title>
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&lt;p&gt;CAMBRIDGE, Mass., June  29, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced the company will host a conference call and live webcast on Thursday, July 30, 2026, at 8:00 a.m. ET to report its second quarter 2026 financial results and business highlights.&lt;/p&gt;  &lt;p&gt;The live webcast will be accessible on the Investors section of the company’s website (&lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=iCmeZkB4CgCj9PhdRDBfePGSVOX6QVTdySeKBM--ebjy49GrrIkAGN3fap2yaupYWPoDsWOi21CIZUlUbjbNyw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;www.agios.com&lt;/a&gt;) under the “Events &amp;amp; Presentations” tab. A replay of the webcast will be available on the company’s website approximately</description>
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   <title>Agios to Host Second Quarter 2026 Financial Results Conference Call and Webcast on July 30 at 8:00 a.m. ET</title>
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&lt;p&gt;CAMBRIDGE, Mass., June  29, 2026  (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (Nasdaq: AGIO), a commercial-stage biopharmaceutical company focused on delivering innovative medicines for patients with rare diseases, today announced the company will host a conference call and live webcast on Thursday, July 30, 2026, at 8:00 a.m. ET to report its second quarter 2026 financial results and business highlights.&lt;/p&gt;  &lt;p&gt;The live webcast will be accessible on the Investors section of the company’s website (&lt;a target=&quot;_blank&quot; href=&quot;https://www.globenewswire.com/Tracker?data=iCmeZkB4CgCj9PhdRDBfePGSVOX6QVTdySeKBM--ebjy49GrrIkAGN3fap2yaupYWPoDsWOi21CIZUlUbjbNyw==&quot; rel=&quot;nofollow&quot; target=&quot;_blank&quot;&gt;www.agios.com&lt;/a&gt;) under the “Events &amp;amp; Presentations” tab. A replay of the webcast will be available on the company’s website approximately</description>
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