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   <title>Form  SCHEDULE 13D/A  Adagene Inc.                           Filed by: Luo Peter</title>
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   <title>Form  SCHEDULE 13D/A  Adagene Inc.                           Filed by: Luo Peter</title>
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   <title>Form  SCHEDULE 13G/A  Adagene Inc.                           Filed by: WuXi PharmaTech Healthcare Fund I L.P.</title>
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   <title>Form  SCHEDULE 13G/A  Adagene Inc.                           Filed by: WuXi PharmaTech Healthcare Fund I L.P.</title>
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   <title>Adagene to Participate in Two Upcoming Investor Conferences</title>
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&lt;p align=&quot;left&quot;&gt;SAN DIEGO and SUZHOU, China, May  12, 2026  (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene or the Company”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced that senior management will participate in one-on-one investor meetings and a fireside chat at the Stifel Annual Virtual Oncology Event on May 19-20, 2026 and one-on-one investor meetings at the Jefferies LLC Global Healthcare Conference being held June 2-4, 2026 in New York, NY.&lt;/p&gt;    &lt;p&gt;&lt;strong&gt;Stifel Annual Virtual Oncology Event &lt;/strong&gt;&lt;/p&gt;    &lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;strong&gt;Format:&lt;/strong&gt; Fireside Chat and 1x1 Meetings&lt;/li&gt;&lt;li&gt;&lt;strong&gt;Date/Time:&lt;/strong&gt; Tuesday, May 19, 2026, at 2:30</description>
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   <title>Adagene to Participate in Two Upcoming Investor Conferences</title>
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&lt;p align=&quot;left&quot;&gt;SAN DIEGO and SUZHOU, China, May  12, 2026  (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene or the Company”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced that senior management will participate in one-on-one investor meetings and a fireside chat at the Stifel Annual Virtual Oncology Event on May 19-20, 2026 and one-on-one investor meetings at the Jefferies LLC Global Healthcare Conference being held June 2-4, 2026 in New York, NY.&lt;/p&gt;    &lt;p&gt;&lt;strong&gt;Stifel Annual Virtual Oncology Event &lt;/strong&gt;&lt;/p&gt;    &lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;strong&gt;Format:&lt;/strong&gt; Fireside Chat and 1x1 Meetings&lt;/li&gt;&lt;li&gt;&lt;strong&gt;Date/Time:&lt;/strong&gt; Tuesday, May 19, 2026, at 2:30</description>
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   <title>Adagene to Participate in Two Upcoming Investor Conferences</title>
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&lt;p align=&quot;left&quot;&gt;SAN DIEGO and SUZHOU, China, May  12, 2026  (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene or the Company”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced that senior management will participate in one-on-one investor meetings and a fireside chat at the Stifel Annual Virtual Oncology Event on May 19-20, 2026 and one-on-one investor meetings at the Jefferies LLC Global Healthcare Conference being held June 2-4, 2026 in New York, NY.&lt;/p&gt;    &lt;p&gt;&lt;strong&gt;Stifel Annual Virtual Oncology Event &lt;/strong&gt;&lt;/p&gt;    &lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;strong&gt;Format:&lt;/strong&gt; Fireside Chat and 1x1 Meetings&lt;/li&gt;&lt;li&gt;&lt;strong&gt;Date/Time:&lt;/strong&gt; Tuesday, May 19, 2026, at 2:30</description>
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   <title>Adagene to Participate in Two Upcoming Investor Conferences</title>
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&lt;p align=&quot;left&quot;&gt;SAN DIEGO and SUZHOU, China, May  12, 2026  (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene or the Company”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced that senior management will participate in one-on-one investor meetings and a fireside chat at the Stifel Annual Virtual Oncology Event on May 19-20, 2026 and one-on-one investor meetings at the Jefferies LLC Global Healthcare Conference being held June 2-4, 2026 in New York, NY.&lt;/p&gt;    &lt;p&gt;&lt;strong&gt;Stifel Annual Virtual Oncology Event &lt;/strong&gt;&lt;/p&gt;    &lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;strong&gt;Format:&lt;/strong&gt; Fireside Chat and 1x1 Meetings&lt;/li&gt;&lt;li&gt;&lt;strong&gt;Date/Time:&lt;/strong&gt; Tuesday, May 19, 2026, at 2:30</description>
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   <title>Adagene to Participate in Two Upcoming Investor Conferences</title>
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&lt;p align=&quot;left&quot;&gt;SAN DIEGO and SUZHOU, China, May  12, 2026  (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene or the Company”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced that senior management will participate in one-on-one investor meetings and a fireside chat at the Stifel Annual Virtual Oncology Event on May 19-20, 2026 and one-on-one investor meetings at the Jefferies LLC Global Healthcare Conference being held June 2-4, 2026 in New York, NY.&lt;/p&gt;    &lt;p&gt;&lt;strong&gt;Stifel Annual Virtual Oncology Event &lt;/strong&gt;&lt;/p&gt;    &lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;strong&gt;Format:&lt;/strong&gt; Fireside Chat and 1x1 Meetings&lt;/li&gt;&lt;li&gt;&lt;strong&gt;Date/Time:&lt;/strong&gt; Tuesday, May 19, 2026, at 2:30</description>
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   <title>Adagene to Participate in Two Upcoming Investor Conferences</title>
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&lt;p align=&quot;left&quot;&gt;SAN DIEGO and SUZHOU, China, May  12, 2026  (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene or the Company”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced that senior management will participate in one-on-one investor meetings and a fireside chat at the Stifel Annual Virtual Oncology Event on May 19-20, 2026 and one-on-one investor meetings at the Jefferies LLC Global Healthcare Conference being held June 2-4, 2026 in New York, NY.&lt;/p&gt;    &lt;p&gt;&lt;strong&gt;Stifel Annual Virtual Oncology Event &lt;/strong&gt;&lt;/p&gt;    &lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;strong&gt;Format:&lt;/strong&gt; Fireside Chat and 1x1 Meetings&lt;/li&gt;&lt;li&gt;&lt;strong&gt;Date/Time:&lt;/strong&gt; Tuesday, May 19, 2026, at 2:30</description>
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   <title>Adagene to Participate in Two Upcoming Investor Conferences</title>
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&lt;p align=&quot;left&quot;&gt;SAN DIEGO and SUZHOU, China, May  12, 2026  (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene or the Company”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced that senior management will participate in one-on-one investor meetings and a fireside chat at the Stifel Annual Virtual Oncology Event on May 19-20, 2026 and one-on-one investor meetings at the Jefferies LLC Global Healthcare Conference being held June 2-4, 2026 in New York, NY.&lt;/p&gt;    &lt;p&gt;&lt;strong&gt;Stifel Annual Virtual Oncology Event &lt;/strong&gt;&lt;/p&gt;    &lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;strong&gt;Format:&lt;/strong&gt; Fireside Chat and 1x1 Meetings&lt;/li&gt;&lt;li&gt;&lt;strong&gt;Date/Time:&lt;/strong&gt; Tuesday, May 19, 2026, at 2:30</description>
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   <title>Adagene to Participate in Two Upcoming Investor Conferences</title>
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&lt;p align=&quot;left&quot;&gt;SAN DIEGO and SUZHOU, China, May  12, 2026  (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene or the Company”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced that senior management will participate in one-on-one investor meetings and a fireside chat at the Stifel Annual Virtual Oncology Event on May 19-20, 2026 and one-on-one investor meetings at the Jefferies LLC Global Healthcare Conference being held June 2-4, 2026 in New York, NY.&lt;/p&gt;    &lt;p&gt;&lt;strong&gt;Stifel Annual Virtual Oncology Event &lt;/strong&gt;&lt;/p&gt;    &lt;ul type=&quot;disc&quot;&gt;&lt;li&gt;&lt;strong&gt;Format:&lt;/strong&gt; Fireside Chat and 1x1 Meetings&lt;/li&gt;&lt;li&gt;&lt;strong&gt;Date/Time:&lt;/strong&gt; Tuesday, May 19, 2026, at 2:30</description>
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   <title>Form  SCHEDULE 13G  Adagene Inc.                           Filed by: JANUS HENDERSON GROUP PLC</title>
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   <pubDate>Thu, 07 May 2026 11:30:00 -0400</pubDate>
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   <title>Form  SCHEDULE 13G  Adagene Inc.                           Filed by: JANUS HENDERSON GROUP PLC</title>
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   <title>Adagene presents trial data showing muzastotug combination benefits</title>
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   <description>&lt;p&gt;Adagene Inc. (NASDAQ: ADAG) presented clinical trial data at the American Association for Cancer Research annual meeting showing its drug muzastotug demonstrated improved response rates when combined with existing cancer therapies.&lt;/p&gt;&lt;p&gt;In a Phase 1b/2 study for hepatocellular carcinoma, the triple combination of muzastotug, atezolizumab and bevacizumab showed a 66.7% overall response rate compared to 32.5% for the control arm receiving only atezolizumab and bevacizumab. The study included six patients in the triple combination arm and 40 patients in the control arm.&lt;/p&gt;&lt;p&gt;A separate Phase 1b/2 study evaluated muzastotug combined with pembrolizumab and fruquintinib in microsatellite stable colorectal cancer patients. Results showed</description>
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   <pubDate>Fri, 17 Apr 2026 16:01:44 -0400</pubDate>
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   <title>Adagene presents trial data showing muzastotug combination benefits</title>
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   <description>&lt;p&gt;Adagene Inc. (NASDAQ: ADAG) presented clinical trial data at the American Association for Cancer Research annual meeting showing its drug muzastotug demonstrated improved response rates when combined with existing cancer therapies.&lt;/p&gt;&lt;p&gt;In a Phase 1b/2 study for hepatocellular carcinoma, the triple combination of muzastotug, atezolizumab and bevacizumab showed a 66.7% overall response rate compared to 32.5% for the control arm receiving only atezolizumab and bevacizumab. The study included six patients in the triple combination arm and 40 patients in the control arm.&lt;/p&gt;&lt;p&gt;A separate Phase 1b/2 study evaluated muzastotug combined with pembrolizumab and fruquintinib in microsatellite stable colorectal cancer patients. Results showed</description>
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   <pubDate>Fri, 17 Apr 2026 16:01:44 -0400</pubDate>
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   <title>Adagene Presents Two Posters at AACR 2026 with New Data Highlighting Muzastotug’s Potential as a Backbone Combination Therapy for Multiple Tumor Types</title>
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   <description>&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Triple combination of muzastotug + atezolizumab + bevacizumab resulted in much higher overall response rates (ORR) compared to the atezolizumab + bevacizumab control arm (66.7% vs. 32.5%, respectively by Investigator per HCC-specific Modified RECIST v1.1) as 1L therapy in a Phase 1b/2 trial in locally advanced or metastatic and/or unresectable hepatocellular carcinoma (HCC) patients&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Triple combination of muzastotug + pembrolizumab + fruquintinib exhibited a dose-dependent response (25% and 40% ORR for 10 mg/kg and 15 mg/kg, respectively) in a Phase 1b/2 trial in late-line microsatellite stable colorectal cancer (MSS CRC) patients&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;New data are further</description>
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   <pubDate>Fri, 17 Apr 2026 16:01:00 -0400</pubDate>
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   <title>Adagene Presents Two Posters at AACR 2026 with New Data Highlighting Muzastotug’s Potential as a Backbone Combination Therapy for Multiple Tumor Types</title>
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   <description>&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Triple combination of muzastotug + atezolizumab + bevacizumab resulted in much higher overall response rates (ORR) compared to the atezolizumab + bevacizumab control arm (66.7% vs. 32.5%, respectively by Investigator per HCC-specific Modified RECIST v1.1) as 1L therapy in a Phase 1b/2 trial in locally advanced or metastatic and/or unresectable hepatocellular carcinoma (HCC) patients&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Triple combination of muzastotug + pembrolizumab + fruquintinib exhibited a dose-dependent response (25% and 40% ORR for 10 mg/kg and 15 mg/kg, respectively) in a Phase 1b/2 trial in late-line microsatellite stable colorectal cancer (MSS CRC) patients&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;New data are further</description>
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   <title>Adagene Presents Two Posters at AACR 2026 with New Data Highlighting Muzastotug’s Potential as a Backbone Combination Therapy for Multiple Tumor Types</title>
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   <description>&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Triple combination of muzastotug + atezolizumab + bevacizumab resulted in much higher overall response rates (ORR) compared to the atezolizumab + bevacizumab control arm (66.7% vs. 32.5%, respectively by Investigator per HCC-specific Modified RECIST v1.1) as 1L therapy in a Phase 1b/2 trial in locally advanced or metastatic and/or unresectable hepatocellular carcinoma (HCC) patients&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Triple combination of muzastotug + pembrolizumab + fruquintinib exhibited a dose-dependent response (25% and 40% ORR for 10 mg/kg and 15 mg/kg, respectively) in a Phase 1b/2 trial in late-line microsatellite stable colorectal cancer (MSS CRC) patients&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;New data are further</description>
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   <title>Adagene Presents Two Posters at AACR 2026 with New Data Highlighting Muzastotug’s Potential as a Backbone Combination Therapy for Multiple Tumor Types</title>
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   <description>&lt;p align=&quot;center&quot;&gt;&lt;em&gt;Triple combination of muzastotug + atezolizumab + bevacizumab resulted in much higher overall response rates (ORR) compared to the atezolizumab + bevacizumab control arm (66.7% vs. 32.5%, respectively by Investigator per HCC-specific Modified RECIST v1.1) as 1L therapy in a Phase 1b/2 trial in locally advanced or metastatic and/or unresectable hepatocellular carcinoma (HCC) patients&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;Triple combination of muzastotug + pembrolizumab + fruquintinib exhibited a dose-dependent response (25% and 40% ORR for 10 mg/kg and 15 mg/kg, respectively) in a Phase 1b/2 trial in late-line microsatellite stable colorectal cancer (MSS CRC) patients&lt;/em&gt;&lt;/p&gt;  &lt;p align=&quot;center&quot;&gt;&lt;em&gt;New data are further</description>
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   <title>Form  6-K        Adagene Inc.              For: Apr 17</title>
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   <title>Form  6-K        Adagene Inc.              For: Apr 17</title>
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   <title>Adagene adds Peter Lebowitz to scientific advisory board</title>
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&lt;p&gt;Adagene Inc. (NASDAQ: ADAG) announced the appointment of Peter Lebowitz, MD, Ph.D., to its Scientific and Strategic Advisory Board. The clinical-stage biotechnology company focuses on developing antibody-based cancer immunotherapies.&lt;/p&gt;

&lt;p&gt;Lebowitz currently serves as Chief Executive Officer of Third Arc Bio, a clinical-stage biotech company developing multifunctional antibodies for oncology and immunology applications. He previously held the position of Global Head of Oncology R&amp;D at Johnson &amp; Johnson for 13 years, where he led the development organization that delivered 13 new drugs to market with over 60 approvals.&lt;/p&gt;

&lt;p&gt;During his tenure at Johnson &amp; Johnson, Lebowitz's drug development approach resulted in 12 FDA</description>
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   <pubDate>Tue, 14 Apr 2026 07:01:04 -0400</pubDate>
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&lt;p&gt;Adagene Inc. (NASDAQ: ADAG) announced the appointment of Peter Lebowitz, MD, Ph.D., to its Scientific and Strategic Advisory Board. The clinical-stage biotechnology company focuses on developing antibody-based cancer immunotherapies.&lt;/p&gt;

&lt;p&gt;Lebowitz currently serves as Chief Executive Officer of Third Arc Bio, a clinical-stage biotech company developing multifunctional antibodies for oncology and immunology applications. He previously held the position of Global Head of Oncology R&amp;D at Johnson &amp; Johnson for 13 years, where he led the development organization that delivered 13 new drugs to market with over 60 approvals.&lt;/p&gt;

&lt;p&gt;During his tenure at Johnson &amp; Johnson, Lebowitz's drug development approach resulted in 12 FDA</description>
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   <title>Adagene adds Peter Lebowitz to scientific advisory board</title>
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&lt;p&gt;Adagene Inc. (NASDAQ: ADAG) announced the appointment of Peter Lebowitz, MD, Ph.D., to its Scientific and Strategic Advisory Board. The clinical-stage biotechnology company focuses on developing antibody-based cancer immunotherapies.&lt;/p&gt;

&lt;p&gt;Lebowitz currently serves as Chief Executive Officer of Third Arc Bio, a clinical-stage biotech company developing multifunctional antibodies for oncology and immunology applications. He previously held the position of Global Head of Oncology R&amp;D at Johnson &amp; Johnson for 13 years, where he led the development organization that delivered 13 new drugs to market with over 60 approvals.&lt;/p&gt;

&lt;p&gt;During his tenure at Johnson &amp; Johnson, Lebowitz's drug development approach resulted in 12 FDA</description>
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