Form 4 Alector, Inc. For: Oct 13 Filed by: Wong-Sarad Grace

October 15, 2026 4:05 PM

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person ^*

Wong-Sarad Grace

(Last)

(First)

(Middle)

C/O ALECTOR, INC.

131 OYSTER POINT BLVD, SUITE 600

(Street)

SOUTH SAN FRANCISCO

94080

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
Alector, Inc. [ ALEC ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
Principal Accounting Officer

3. Date of Earliest Transaction (Month/Day/Year)
10/13/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	10/14/2026		A		55,555 ⁽¹⁾	A	$ 0	161,570	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Employee Stock Option (right to buy)	$ 16.46	10/13/2026		D			20,000	⁽²⁾	08/31/2029	Common Stock	20,000	⁽³⁾ ⁽⁴⁾	0	D
Employee Stock Option (right to buy)	$ 1.87	10/13/2026		A		20,000		⁽²⁾	08/31/2029	Common Stock	20,000	⁽³⁾ ⁽⁴⁾	20,000	D
Employee Stock Option (right to buy)	$ 17.15	10/13/2026		D			13,842	⁽²⁾	11/05/2029	Common Stock	13,842	⁽³⁾ ⁽⁴⁾	0	D
Employee Stock Option (right to buy)	$ 1.87	10/13/2026		A		13,842		⁽²⁾	11/05/2029	Common Stock	13,842	⁽³⁾ ⁽⁴⁾	13,842	D
Employee Stock Option (right to buy)	$ 10.24	10/13/2026		D			20,454	⁽²⁾	09/30/2030	Common Stock	20,454	⁽³⁾ ⁽⁴⁾	0	D
Employee Stock Option (right to buy)	$ 1.87	10/13/2026		A		20,454		⁽²⁾	09/30/2030	Common Stock	20,454	⁽³⁾ ⁽⁴⁾	20,454	D
Employee Stock Option (right to buy)	$ 13.56	10/13/2026		D			10,228	⁽²⁾	11/30/2030	Common Stock	10,228	⁽³⁾ ⁽⁴⁾	0	D
Employee Stock Option (right to buy)	$ 1.87	10/13/2026		A		10,228		⁽²⁾	11/30/2030	Common Stock	10,228	⁽³⁾ ⁽⁴⁾	10,228	D
Employee Stock Option (right to buy)	$ 23.7	10/13/2026		D			11,552	⁽²⁾	09/30/2031	Common Stock	11,552	⁽³⁾ ⁽⁴⁾	0	D
Employee Stock Option (right to buy)	$ 1.87	10/13/2026		A		11,552		⁽²⁾	09/30/2031	Common Stock	11,552	⁽³⁾ ⁽⁴⁾	11,552	D
Employee Stock Option (right to buy)	$ 9.46	10/13/2026		D			11,309	⁽²⁾	09/30/2032	Common Stock	11,309	⁽³⁾ ⁽⁴⁾	0	D
Employee Stock Option (right to buy)	$ 1.87	10/13/2026		A		11,309		⁽²⁾	09/30/2032	Common Stock	11,309	⁽³⁾ ⁽⁴⁾	11,309	D
Employee Stock Option (right to buy)	$ 1.88	10/14/2026		A		83,435		⁽⁵⁾	10/13/2036	Common Stock	83,435	$ 0	83,435	D

Explanation of Responses:

1. The reported shares are represented by restricted stock units, or RSUs, which vest in 12 equal quarterly installments beginning on December 1, 2026.

2. The shares subject to the option are fully vested and immediately exercisable.

3. The transactions reported herein reflect a one-time stock option repricing (the "Option Repricing") effective on October 13, 2026 (the "Effective Date"). The Option Repricing applies to stock options with exercise prices greater than $1.87 per share held by all continuing employees of the Issuer as of the Effective Date.

4. Pursuant to the Option Repricing, the exercise price of the repriced options, including the reported option, has been amended to reduce the exercise price to $1.87 per share, the closing price of the Issuer's common stock on the Effective Date. However, if an employee exercises a repriced Eligible Option before the end of a "Retention Period" that begins on the Effective Date of the Option Repricing and ends on the earliest to occur of the following: (i) one year following the Effective Date; (ii) a Change in Control, as defined in the Issuer's 2019 Equity Incentive Plan, as amended (the "2019 Plan"); and (iii) the optionholder's death or Disability (as defined in the 2019 Plan), then the employee will be required to pay a premium exercise price that is equal to the original exercise price per share of such option. There was no change to the vesting schedules, expiration dates or number of shares underlying the repriced options.

5. Shares subject to the option vest in 48 equal monthly installments beginning on November 13, 2026.

	/s/ Grace Wong-Sarad	10/15/2026
	** Signature of Reporting Person	Date
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Form 4 Alector, Inc. For: Oct 13 Filed by: Wong-Sarad Grace

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