Invezing.com - U.S. stock futures pointed lower on Monday, signaling a cautious start to the trading week as investors kept tabs on bond-market jitters and the outlook for Federal Reserve interest rates.

By 06:08 ET (10:08 GMT), the Dow futures contract had fallen 92 points, or 0.2%, S&P 500 futures had dropped 13 points, or 0.2%, and Nasdaq 100 futures had dipped 69 points, or 0.2%.

Here are some of the biggest premarket U.S. stock movers today:

Shares of Group 1 Automotive fell 2.1% after Morgan Stanley downgraded the stock to Underweight from Equalweight and cut its price target to $232 from $300.

Analyst Daniela Haigian pointed to an unfavorable combination of company-specific execution risks and broader industry headwinds, arguing that the company enters the third quarter with diminishing room for error and an earnings recovery that has already been pushed further out.

Morgan Stanley cut its Q3 earnings-per-share estimate by 11% and its fiscal 2027 EPS estimate by 6%, putting both forecasts meaningfully below Wall Street consensus. The bank highlighted disruption from the ongoing U.S. dealership rebranding effort, difficulties sourcing used vehicles and the complexity of absorbing the pending Hennessy dealership acquisition.

Morgan Stanley also pointed to AutoNation’s recent guidance reduction as a warning for the broader sector, with pressure on new-vehicle gross profit per unit and high-margin parts and service revenue. The downgrade follows a similar move by Citi in late September, when the bank lowered its price target on Group 1 Automotive, citing softer retail sales and rising borrowing costs.

Harley-Davidson stock surged 3.8% in premarket trading after Citi upgraded the shares to Buy from Neutral and raised its price target to $33 from $31. The upgrade marked a notable shift in the firm’s view of the motorcycle maker after maintaining a cautious stance through much of 2026.

Citi’s upgrade comes as several factors have improved beneath the surface. Multiple insiders have bought shares in recent months, with net insider buying exceeding $1.3 million. Harley-Davidson also beat Wall Street’s earnings expectations in the second quarter and raised its full-year guidance for motorcycle retail unit sales and operating income, providing further support for the bullish view.

Cerebras Systems shares rose as much as 6.1% in premarket trading after OpenAI CEO Sam Altman described the company as “a close partner” of OpenAI. Altman said the two companies have “a deep engagement pushing on the frontiers of speed,” addressing recent speculation about the relationship between the two firms.

Barclays analyst Tom O’Malley said OpenAI’s relationship with Cerebras “remains strong,” noting that while Nvidia is running OpenAI’s GPT-6.1 Ultrafast, Cerebras remains the preferred provider but is limited by supply. O’Malley said the recent selloff in Cerebras shares was “overdone,” pointing to Altman’s comments as a positive signal.

U.S.-listed shares of Brazilian companies surged in premarket trading after right-wing Senator Flavio Bolsonaro outperformed polls in the first round of Brazil’s presidential election, prompting expectations of a broad rally in Brazilian markets. Bolsonaro received 47% of the vote and will face President Luiz Inacio Lula da Silva, who received about 45%, in a runoff near the end of the month. Polls had expected Lula to finish first.

Petrobras ADRs jumped about 10% in U.S. premarket trading, while Banco Bradesco and Itau Unibanco each surged more than 9%. Nu Holdings soared 10.5%, Vale gained 8%, Ambev rose 7% and Embraer advanced more than 6%. Madrid-listed Telefonica and Santander also rose nearly 2% each.

Zentalis Pharmaceuticals stock rose 4.4% in premarket trading after Leerink Partners initiated coverage of the company with an Outperform rating and an $8 price target, sharply reversing its previous Market Perform stance and $4 target.

The move signals that the firm now sees greater potential for Zentalis’ lead oncology asset, azenosertib, an investigational WEE1 inhibitor, in platinum-resistant ovarian cancer.

Leslie’s stock plunged 23.1% in premarket trading to $0.112 as the pool and spa care retailer approached the final hours of its Nasdaq listing. Nasdaq is set to suspend trading in the shares at the opening of business on October 6, 2026.

Nasdaq notified Leslie’s on September 25 that its shares were subject to delisting after closing below the exchange’s $1.00 minimum bid-price requirement for 30 consecutive business days. The company has confirmed that it does not intend to appeal the decision and expects its shares to move to an over-the-counter venue, with no assurance of continued liquidity.

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