Investing.com - U.S. stock index futures edged higher on Friday, as a decline in oil prices helped soothe investor jitters after a surge in Treasury yields spooked Wall Street this week.

By 05:24 ET (09:24 GMT), the Dow futures contract had risen 137 points, or 0.3%, S&P 500 futures had gained 23 points, or 0.3%, and Nasdaq 100 futures had climbed 178 points, or 0.6%.

Here are some of the biggest premarket U.S. stock movers today:

Akamai Technologies surged 21.3% in premarket trading after the company announced a seven-year, $11.6 billion cloud services commitment from AI company Anthropic. The agreement is designed to support Anthropic’s growing CPU workload demands across Akamai Cloud’s distributed infrastructure.

The deal also includes provisions allowing the relationship to expand by up to an additional $9 billion, potentially taking the total commitment to about $20 billion. Akamai also disclosed a hardware supply agreement with Lenovo and authorized contract manufacturer Jabil to procure about $1.7 billion in memory components, adding to the scale of its planned infrastructure investment.

People Incorporated rose 6.5% in premarket trading after The Wall Street Journal reported that MGM Resorts International (NYSE: MGM) is weighing a potential takeover bid for Barry Diller’s media conglomerate, with an offer potentially coming within days.

The report comes just one day after People Incorporated withdrew its own $48.30-per-share cash proposal to acquire MGM’s remaining public shares, citing the complexity of the transaction and an inability to meet the necessary conditions.

Select Water Solutions rose 5,5% after announcing a definitive agreement to acquire Pilot Water Solutions for $700 million, plus up to $15 million in potential contingent consideration.

The transaction includes $600 million in cash and $100 million in Class A common stock. Select Water will acquire the private water midstream company, which primarily operates in the Delaware Basin, on a debt-free basis.

Prime Medicine climbed 11.7% in after-hours trading to $3.49 after the U.S. Food and Drug Administration cleared its Investigational New Drug application for PM647, an investigational in vivo Prime Editor designed to correct the E342K mutation in the SERPINA1 gene, the root cause of Alpha-1 Antitrypsin Deficiency.

The FDA clearance paves the way for a global first-in-human Phase 1/2 clinical trial. The initial study will enroll adults with lung-only manifestations of the disease, with a separate cohort for patients with significant liver involvement expected to be added after tolerability is established.

STAAR Surgical rose 2.2% in after-hours trading after its board authorized a $50 million share repurchase program. The company said the program will run for 12 months, although the board can extend or shorten the period, with the timing and amount of purchases left to management based on market conditions.

Comcast slipped 1.6% in premarket trading to $21.77 after KeyBanc downgraded the stock to Underweight from Sector Weight and set an $18 price target.

KeyBanc cited deteriorating broadband net additions, pressure on average revenue per user, worsening Connectivity & Platforms EBITDA and a steeper-than-expected decline in Theme Parks performance. The analysts also said they do not view the planned NBCUniversal spin-off as a meaningful near-term catalyst for the shares.

Twilio fell 3.7% in premarket trading after HSBC downgraded the stock to Reduce from Hold and assigned a $211 price target.

The bank argued that investors may have moved too quickly in viewing Twilio as a major beneficiary of Meta’s Muse AI agent, which launched on Sept. 8 and helped send Twilio shares roughly 30% higher in the weeks that followed.

Zscaler fell 3.6% after the cloud security company announced a change at the top of its revenue organization. Ross Tackett will become Chief Revenue Officer on Oct. 1, succeeding Mike Rich.

Tackett has led Zscaler’s worldwide sales function for the past three years and has more than three decades of technology sales experience, including stints at ServiceNow and Dell. The leadership change comes ahead of Zscaler’s Investor Day on Oct. 6, adding uncertainty around the company’s near-term go-to-market strategy and sales pipeline.

Scholastic tumbled 11% after the children’s publishing and education company reported fiscal first-quarter 2027 results that missed Wall Street expectations on both revenue and earnings.

Revenue fell 3.9% year over year to $216.8 million, roughly 3.5% below analyst estimates. Adjusted loss per share came in at $3.63, wider than the consensus forecast of about $3.40.

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