Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
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Legend Biotech Announces Presentations at ASCO 2026

On May 21, 2026, Legend Biotech Corporation (“Legend Biotech”) issued a press release announcing that it will present new data at the 2026 American Society of Clinical Oncology (“ASCO”) Annual Meeting, including a rapid oral presentation highlighting preliminary Phase 1 data for LB2102, its investigational DLL3-targeted CAR-T therapy for relapsed or refractory small-cell lung cancer (SCLC) and large-cell neuroendocrine carcinoma (LCNEC), and will also present new data on CARVYKTI® (ciltacabtagene autoleucel; cilta-cel).

Legend Biotech also announced in the press release that during the 2026 ASCO Annual Meeting taking place in Chicago, IL, Legend Biotech will host a live webcast event for investors on Sunday, May 31, 2026, at 6:15 PM CT, where Ying Huang, Ph.D., Chief Executive Officer, will host expert clinicians as they review how CARVYKTI is transforming the multiple myeloma treatment landscape.

The press release is attached to this Form 6-K as Exhibit 99.1.

This report on Form 6-K is hereby incorporated herein by reference in the registration statements of Legend Biotech on Form F-3 (Nos. 333-278050, 333-272222, and 333-257625) and Form S-8 (No. 333-239478 and 333-283217), to the extent not superseded by documents or reports subsequently filed.

EXHIBIT INDEX

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

ATTACHMENTS / EXHIBITS

PRESS RELEASE