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Oklo partners with NVIDIA and Los Alamos for nuclear fuel research

April 23, 2026 8:02 AM

Oklo Inc. (NYSE: OKLO) announced an agreement with NVIDIA and Los Alamos National Laboratory to advance nuclear infrastructure and AI-enabled research at Los Alamos. The collaboration aims to support the federal government's Genesis Mission through nuclear fuel validation work.

The partnership combines Oklo's sodium-fast-reactor technology, NVIDIA's AI infrastructure, and Los Alamos National Laboratory's materials science expertise. The collaboration will focus on developing physics and chemistry-based AI models for fuel validation, materials science research for plutonium-bearing fuels, and power generation studies for nuclear-powered AI facilities.

"This agreement brings together reactor deployment, high-performance compute, and world-class fuel and materials science expertise," said Oklo co-founder and CEO Jacob DeWitte. "We believe this will advance our plutonium-bearing fuel work on Oklo's Pluto reactor, which was selected under DOE's Reactor Pilot Program, and help bring resilient power in support of the Genesis Mission."

The initiative will include integrated solutions for nuclear-powered AI factories, AI model development for nuclear fuel research and development, grid stabilization studies, and materials science efforts focused on plutonium-bearing fuel. The parties also plan proof of concept work for developing a nuclear-powered AI factory.

Oklo previously received the first site use permit from the U.S. Department of Energy for a commercial advanced fission plant and submitted the first custom combined license application for an advanced reactor to the U.S. Nuclear Regulatory Commission. The company is developing fast fission power plants and nuclear fuel recycling technologies.

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