Investing.com -- Shares of Insmed rose about 7% after positive late-stage data for its lung disease drug Arikayce, with analysts pointing to a potential expansion in the drug’s addressable market.

Morgan Stanley said the Phase 3b ENCORE study met both primary and secondary endpoints, including improved respiratory symptom scores and higher rates of culture conversion.



The results support expanding Arikayce’s use beyond refractory patients, increasing the target population from about 30,000 to roughly 200000 patients across the U.S. and Japan.

The company plans to file for a label expansion in the second half of 2026. Morgan Stanley said the revenue impact is likely from 2027, adding that investor focus in the near term will remain on the launch of Insmed’s other drug, Brinsupri.

Wolfe Research also viewed the data positively, highlighting durable clinical benefits and a safety profile consistent with prior studies. It noted improvements in symptom scores continued through 15 months, alongside earlier and more sustained culture conversion.

Both firms flagged that Arikayce showed higher rates of adverse events than the control arm, but said these were in line with known side effects. Discontinuation rates were lower than in earlier trials, which analysts attributed to better patient and physician familiarity with the treatment.

Analysts said the expanded label could materially increase long-term growth potential, though near-term stock moves may hinge on other catalysts, including data from additional programs.

Wolfe said attention is likely to shift back to Brinsupri, where it forecasts revenue ahead of consensus and expects momentum to build in the second half of the year, supporting earnings growth and a potential move toward profitability.