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Form SCHEDULE 13D/A IRONWOOD PHARMACEUTICALS Filed by: Sarissa Capital Management LP

March 19, 2026 6:35 PM





If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).




schemaVersion:


SCHEDULE 13D




Comment for Type of Reporting Person:
Calculations of the percentage set forth in Row 13 are based upon the 163,058,316 Shares stated to be outstanding as of January 31, 2026 by the Issuer in the Issuer's Form 10-K filed with the Securities and Exchange Commission on February 26, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The amount set forth in each of Rows 7 and 9 represents shares acquired by Dr. Denner in his capacity as a director of the Issuer. Calculations of the percentage set forth in Row 13 are based upon the 163,058,316 Shares stated to be outstanding as of January 31, 2026 by the Issuer in the Issuer's Form 10-K filed with the Securities and Exchange Commission on February 26, 2026.


SCHEDULE 13D


Sarissa Capital Management LP
Signature:/s/Alexander J. Denner, Ph.D.
Name/Title:Alexander J. Denner, Ph.D., Chief Investment Officer
Date:03/19/2026
Alexander J. Denner
Signature:/s/Alexander J. Denner, Ph.D.
Name/Title:Alexander J. Denner, Ph.D., Chief Investment Officer
Date:03/19/2026

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