NVIDIA (NASDAQ: NVDA) announced the expansion of its open model families to power agentic, physical and healthcare AI applications during its GTC conference. The company introduced several new models across different domains, according to a press release statement.

The NVIDIA Nemotron 3 family includes three new omni-understanding models. Nemotron 3 Ultra delivers frontier-level intelligence with 5x throughput efficiency using the NVFP4 format on the NVIDIA Blackwell platform. Nemotron 3 Omni integrates audio, vision and language understanding for AI agents to extract insights from videos and documents. Nemotron 3 VoiceChat supports real-time conversations combining speech recognition, language processing and text-to-speech capabilities.

For physical AI applications, NVIDIA released Isaac GR00T N1.7, an open reasoning vision language action model for humanoids that is commercially viable for deployment. NVIDIA Alpamayo 1.5 provides reasoning capabilities for autonomous vehicles with navigation guidance and multi-camera support. The company also previewed Cosmos 3, described as the first world foundation model to unify synthetic world generation and physical AI reasoning.

In healthcare and life sciences, NVIDIA expanded its BioNeMo platform with the Proteina-Complexa model for protein binder design that accelerates drug discovery. The company collaborated with EMBL's European Bioinformatics Institute, Google DeepMind and Seoul National University to expand the AlphaFold Protein Structure Database with 30 million protein complex predictions and 1.7 million high-confidence predictions.

Companies adopting these models include CodeRabbit, CrowdStrike, Cursor, Factory, ServiceNow and Perplexity for agentic AI applications. LG Electronics and Milestone Systems are using the models for physical AI, while Novo Nordisk, Viva Biotech and Manifold Bio are implementing them for healthcare applications.

The models are available on GitHub, Hugging Face, cloud platforms and build.nvidia.com, with many offered as NVIDIA NIM microservices for deployment on NVIDIA-accelerated infrastructure.