WAVE Life Sciences (NASDAQ: WVE) reported Q4 EPS of ($0.59), $0.02 better than the analyst estimate of ($0.61). Revenue for the quarter came in at $9.44 million versus the consensus estimate of $9.75 million.

“Wave is entering 2021 with depth and diversity throughout our pipeline and platform, the result of focused and deliberate execution, and a steadfast commitment to leading a new era of RNA therapeutics. Despite headwinds from the COVID-19 pandemic, we advanced our pipeline, significantly evolved our platform, announced our first ADAR editing program and added considerable talent to our innovative and driven team,” said Paul Bolno, MD, MBA, President and Chief Executive Officer of Wave Life Sciences. “We are poised to bring five clinical programs forward in 2021, including three programs in Huntington’s disease, a fourth program for ALS and FTD and a fifth program for exon 53 skipping in DMD. We remain on track to announce data from the Phase 1b/2a PRECISION-HD1 and PRECISION-HD2 trials at the end of the first quarter of 2021 and are excited about adding our next set of clinical programs incorporating novel PN backbone chemistry modifications, which preclinically have been shown to increase potency, exposure and durability in our growing portfolio of investigational stereopure oligonucleotides. Finally, we strengthened our balance sheet in September 2020 to support our pipeline and discovery work, extending our cash runway into the second quarter of 2023 and ensuring Wave is well-positioned to unlock potential and growth well beyond 2021.”

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