Today's Pre-Open Stock Movers:

Alpine Immune Sciences, Inc. (NASDAQ: ALPN) 240% HIGHER; The company and AbbVie Inc. (NYSE: ABBV), a research-based global biopharmaceutical company, today announced an exclusive worldwide option and license agreement for ALPN-101, a first-in-class dual CD28/ICOS costimulation antagonist.

Aethlon Medical, Inc. (Nasdaq: AEMD) 155% HIGHER; announced today that the U.S. Food and Drug Administration (FDA) has approved a supplement to the Company's existing Investigational Device Exemption (IDE) for the Company's Hemopurifier® in viral disease to allow for the testing of the Hemopurifier in patients with SARS-CoV-2/COVID-19 in a new feasibility study.

Eloxx Pharmaceuticals, Inc., (NASDAQ: ELOX) 57% HIGHER; announced that enrollment in its Phase 2 clinical trial for ELX-02 in cystic fibrosis has been resumed in Israel and Europe after being temporarily paused in response to the COVID-19 pandemic.

Orion Group Holdings, Inc. (NYSE: ORN) 21.3% HIGHER; announced contract awards totaling approximately $17 million.

Leap Therapeutics, Inc. (NASDAQ: LPTX) 15.9% LOWER; announced that it has commenced an underwritten public offering of its common stock and, in lieu of common stock, Leap intends to offer and sell to certain investors pre-funded warrants to purchase shares of its common stock

QuickLogic Corporation (NASDAQ: QUIK) 12.8% LOWER; announced that it intends to offer and sell shares of its common stock in an underwritten registered public offering.

Adamas Pharmaceuticals, Inc. (Nasdaq: ADMS) 12.2% LOWER; announced the completion of its evaluation of ADS-5102 in multiple sclerosis patients with walking impairment (MSW).

Selecta Biosciences, Inc. (NASDAQ: SELB) 11% HIGHER; Sarepta Therapeutics (NASDAQ: SRPT), the leader in precision genetic medicine for rare diseases, and Selecta Biosciences, Inc. (NASDAQ: SELB) today announced that they have entered into a Research License and Option agreement granting Sarepta an option to license the rights to develop and commercialize Selectas immune tolerance platform, ImmTOR, for use in Duchenne muscular dystrophy (DMD) and certain limb-girdle muscular dystrophies (LGMDs). In advance of exercising its option, Sarepta will conduct research and evaluate the utility of ImmTOR to minimize or prevent the formation of neutralizing antibodies (NAb) to adeno-associated virus (AAV) in connection with the administration of Sareptas DMD and LGMD gene therapy candidates.

Enphase Energy, Inc. (NASDAQ: ENPH) 10% HIGHER; defended by analysts after yesterday's short report.

Catalyst Biosciences, Inc. (NASDAQ: CBIO) 8.3% LOWER; announced that it is offering shares of its common stock in an underwritten public offering.

Dada Nexus (NASDAQ: DADA) 7.5% HIGHER; Walmart (NYSE: WMT) disclosed in a 13G filing that it owned 94,981,280 shares, or a 10.7% stake, in the company. DADA IPO'd on June 5 and Walmart was a pre-IPO investor of the company.

Biogen (NASDAQ: BIIB) 7.5% LOWER; Tecfidera Patent Invalidated in Mylan (NASDAQ: MYL) Dispute - Bloomberg

Kratos Defense & Security Solutions, Inc. (Nasdaq: KTOS) 7% LOWER; announced that it intends to offer for sale $200,000,000 of shares of its common stock in an underwritten offering pursuant to an effective shelf registration statement filed with the Securities and Exchange Commission.

IVERIC bio, Inc. (Nasdaq: ISEE) 6.8% LOWER; announced that it is commencing an underwritten public offering of $50.0 million of shares of its common stock (or pre-funded warrants to purchase its common stock in lieu thereof).

Carnival (NYSE: CCL) 5.9% LOWER; Reported Preliminary Q2 Adj-Loss of $3.30/Share, Revenues Fall from $4.8B to $700M

ABM Industries (NYSE: ABM) 5.8% HIGHER; reported Q2 EPS of $0.60, $0.31 better than the analyst estimate of $0.29. Revenue for the quarter came in at $1.5 billion versus the consensus estimate of $1.49 billion.

Spotify (NYSE: SPOT) 5% HIGHER; Kim Kardashian West for an exclusive podcast.

United States Steel Corporation (NYSE: X) 5% LOWER; announced that it has commenced an underwritten public offering of 50,000,000 shares of common stock. U. S. Steel intends to grant the underwriter a 30-day option to purchase up to 7,500,000 additional shares of common stock from the company.

Neoleukin Therapeutics (NASDAQ: NLTX) 3.3% HIGHER; Mizuho Securities initiates coverage on with a Buy rating and a price target of $21.00.

OrthoPediatrics Corp. (Nasdaq: KIDS) 3% LOWER; announced today that it is commencing an underwritten public offering of its common stock.

Fox Factory Holding Corp. (NASDAQ: FOXF) 2.5% LOWER; announced today that it has commenced an underwritten public offering of 2,000,000 shares

QEP Resources (NYSE: QEP) 1.9% HIGHER; MKM Partners initiates coverage on with a Buy rating and a price target of $3.00.

Shopify (NYSE: SHOP) 1.9% HIGHER; RBC Capital raised the price target to a 'Street High' $1,000.00 (from $825.00) while maintaining an Outperform rating.

Nikola (NASDAQ: NKLA) 1.8% HIGHER; CEO Trevor Milton said Bloomberg writer Ed Ludlow should be let go after the earlier negative article, which stated Milton exaggerated the capability of the company's truck.

Tesla (NASDAQ: TSLA) 1% HIGHER; Jefferies analyst Philippe Houchois raised the price target on Tesla (NASDAQ: TSLA) to a 'Street High' $1,200.00 (from $650.00) on the belief that Covid-19 is an accelerator of the transition to EVs and renewables, from both consumers and public policy