Cyclacel Pharma (NASDAQ: CYCC) reported Q4 EPS of ($0.62), versus ($1.95) reported last year. Revenue for the quarter came in at $150 thousand, versus $0 reported last year.

"We are executing on our targeted oncology strategy with the objective of delivering data readouts from multiple clinical programs,” said Spiro Rombotis, President and Chief Executive Officer. “At the heart of our business strategy is targeting patients with overexpression of cancer resistance proteins, including Mcl-1, MYC, cyclin E, and inherited mutations in DNA damage pathways, such as BRCA. We believe CYC065 is the first investigational drug to have consistently demonstrated durable suppression of Mcl-1 at tolerable dosing in patients. We have treated patients in two out of four studies under our MD Anderson collaboration, the Phase 1 study of a combination of CYC065 and venetoclax in relapsed/refractory CLL and the first-in-human, Phase 1 study of CYC140 in advanced leukemias. Protocols for the other two studies have been finalized and will be submitted to institutional review boards. The first two patients with BRCA mutant breast cancer were treated in the sapacitabine and olaparib IST. With estimated capital on hand until the end of 2020 we look forward to reporting data from our ongoing clinical studies and realizing shareholder value from our targeted drug pipeline.”

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