Pre-Open Stock Movers 01/06: (CNAT) (CCXI) (MBLY) Higher; (CMG) (VRX) (AAPL) Lower (more...)

January 6, 2016 9:28 AM EST
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Price: $0.56 --0%

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Conatus Pharmaceuticals (NASDAQ: CNAT) 24.6% HIGHER; three-month, double-blind, placebo-controlled stage of the company’s multicenter Phase 2 Liver Cirrhosis clinical trial showed a statistically significant reduction in caspase-cleaved cytokeratin 18 (cCK18) vs. placebo (p=0.04) in the overall patient population when adjusted for differences between treatment and placebo groups in baseline Model for End-stage Liver Disease (MELD)1 score and disease etiology as specified in the trial statistical analysis plan.

ChemoCentryx, Inc., (Nasdaq: CCXI) 23.9% HIGHER; announced positive top-line data from its Phase II CLEAR trial with CCX168 in patients with anti-neutrophil cytoplasmic antibody (ANCA) -associated vasculitis, or AAV. CCX168 is a potent orally-administered small molecule that is a selective inhibitor of the complement C5a receptor, or C5aR. CCX168 is the lead drug candidate in the Company's orphan and rare disease program.

Epizyme, Inc. (NASDAQ: EPZM) 10% LOWER; announced that it intends to offer and sell up to $120,000,000 of shares of its common stock in an underwritten public offering. Epizyme intends to grant the underwriters a 30-day option to purchase up to an additional $18,000,000 of shares of its common stock. All of the shares of common stock to be sold in the offering will be offered by Epizyme. Also, updates on Tazemetostat Phase 2; Plans Trial.

MannKind Corp. (NASDAQ: MNKD) 10% LOWER; continues lower after Sanofi opted to exit the Afrezza partnership. Piper Jaffray cuts price target to $0.05 on bankruptcy risk.

Cempra, Inc. (Nasdaq: CEMP) 7% LOWER; announced its intention to offer and sell shares of its common stock with an aggregate public offering price of approximately $175 million in an underwritten public offering pursuant to its existing shelf registration statement. The company also intends to grant to the underwriters a 30-day option to purchase up to an additional 15% of the shares of common stock sold in the public offering with an aggregate public offering price of $26.25 million.

Mobileye N.V. (NASDAQ: MBLY) 6% HIGHER; VW deal disclosed at CES. Evercore ISI sees it adding $10/share.

Iconix Brand (NASDAQ: ICON) 5.6% HIGHER; Sports Direct International disclosed a new 9%, or 4,339,933 share, stake in the company.

Otonomy, Inc. (NASDAQ: OTIC) 5.5% LOWER; commenced an underwritten public offering of approximately $100 million of its common stock. All shares of common stock to be sold in the offering will be offered by Otonomy. In addition, Otonomy expects to grant the underwriters a 30-day option to purchase up to an additional approximately $15 million of its common stock. The number of shares to be offered and the price for the proposed offering have not yet been determined.

Otonomy, Inc. (NASDAQ: OTIC) 5.5% LOWER; commenced an underwritten public offering of approximately $100 million of its common stock. All shares of common stock to be sold in the offering will be offered by Otonomy. In addition, Otonomy expects to grant the underwriters a 30-day option to purchase up to an additional approximately $15 million of its common stock. The number of shares to be offered and the price for the proposed offering have not yet been determined.

Idera Pharmaceuticals (NASDAQ: IDRA) 5% HIGHER; Wedbush initiates coverage with a Outperform rating and a price target of $6.00.

TASER International (NASDAQ: TASR) 5% HIGHER; JPMorgan assumed coverage on with an Overweight rating and a price target of $25.00

Qlik Technologies (NASDAQ: QLIK) 5% LOWER; Pacific Crest downgraded from Overweight to Sector Weight.

ACADIA Pharmaceuticals Inc. (NASDAQ: ACAD) 4.4% LOWER; intends to offer and sell, subject to market and other conditions, $300,000,000 of shares of its common stock in an underwritten public offering. There can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

TherapeuticsMD, Inc. (NYSE: TXMD) 4.2% LOWER; announced the launch of an underwritten public offering of $125 million of shares of its common stock. TherapeuticsMD also expects to grant the underwriters a 30-day option to purchase up to an additional 15% of the shares of common stock. All of the shares in the offering are to be sold by TherapeuticsMD. The offering is subject to market conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

Prothena Corporation plc (NASDAQ: PRTA) 3.4% LOWER; commenced an underwritten public offering of 2,250,000 of its ordinary shares. All of the ordinary shares in the offering will be sold by Prothena. In addition, Prothena has granted the underwriters a 30-day option to purchase up to an additional 337,500 of its ordinary shares.

Valeant Pharmaceuticals International, Inc. (NYSE: VRX) 3.2% LOWER; announced that Howard B. Schiller has been appointed interim chief executive officer of Valeant, effective immediately.

Sonic Corp (NASDAQ: SONC) 3% LOWER; reported Q1 EPS of $0.24, $0.01 better than the analyst estimate of $0.23. Revenue for the quarter came in at $145.8 million versus the consensus estimate of $144.28 million.

Chipotle Mexican Grill, Inc. (NYSE: CMG) 3% LOWER; Q4 Comparable restaurant sales were -14.6%; Restaurant level operating margins of approximately 20% to 21%; Diluted earnings per share in the range of $1.70 to $1.90;.

Apple Inc. (NASDAQ: AAPL) 2% LOWER; supplier Foxconn sought to layoff workers, downgraded at Rosenblatt

bluebird bio (NASDAQ: BLUE) 1.6% HIGHER; Janney Capital initiated coverage with a Buy rating and a price target of $91.00.

Acadia Healthcare Company, Inc. (NASDAQ: ACHC) 1% LOWER; announced a proposed underwritten public offering of 10,000,000 shares of its common stock.



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